Abstract:
:Children who are treated for congenital cataracts later exhibit impairments in configural face analysis. This has been explained in terms of a critical period for the acquisition of normal face processing. Here, we consider a more parsimonious account according to which deficits in configural analysis result from the abnormally high initial retinal acuity that children treated for cataracts experience, relative to typical newborns. According to this proposal, the initial period of low retinal acuity characteristic of normal visual development induces extended spatial processing in the cortex that is important for configural face judgments. As a computational test of this hypothesis, we examined the effects of training with high-resolution or blurred images, and staged combinations, on the receptive fields and performance of a convolutional neural network. The results show that commencing training with blurred images creates receptive fields that integrate information across larger image areas and leads to improved performance and better generalization across a range of resolutions. These findings offer an explanation for the observed face recognition impairments after late treatment of congenital blindness, suggest an adaptive function for the acuity trajectory in normal development, and provide a scheme for improving the performance of computational face recognition systems.
journal_name
Proc Natl Acad Sci U S Aauthors
Vogelsang L,Gilad-Gutnick S,Ehrenberg E,Yonas A,Diamond S,Held R,Sinha Pdoi
10.1073/pnas.1800901115subject
Has Abstractpub_date
2018-10-30 00:00:00pages
11333-11338issue
44eissn
0027-8424issn
1091-6490pii
1800901115journal_volume
115pub_type
杂志文章abstract::The regulation of major histocompatibility complex class II gene expression is directly involved in the control of normal and abnormal immune responses. In humans, HLA-DR, -DQ, and -DP class II heterodimers are encoded by a family of alpha- and beta-chain genes clustered in the major histocompatibility complex. Their ...
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