Bufonid herpesvirus 1 (BfHV1) associated dermatitis and mortality in free ranging common toads (Bufo bufo) in Switzerland.

Abstract:

:Here we report the discovery and partial characterization of a novel herpesvirus tentatively named Bufonid herpesvirus 1 (BfHV1) from severe dermatitis in free ranging common toads (Bufo bufo) in Switzerland. The disease has been observed in toads every year since 2014, in spring, during the mating season, at different and distant locations. The virus is found in the skin and occasionally in the brain of infected toads. The genome of the virus is at least 158 Kb long and contains at least 152 open reading frames with a minimal length of 270 nt. The genome of BfHV1 contains all the signature genes that are present in alloherpesviruses. Phylogenetic analysis based on the amino acid sequence of the DNA polymerase and terminase proteins positions the novel virus among the members of the genus Batrachovirus, family Alloherpesviridae. This is the first herpesvirus ever characterized in common toads.

journal_name

Sci Rep

journal_title

Scientific reports

authors

Origgi FC,Schmidt BR,Lohmann P,Otten P,Meier RK,Pisano SRR,Moore-Jones G,Tecilla M,Sattler U,Wahli T,Gaschen V,Stoffel MH

doi

10.1038/s41598-018-32841-0

subject

Has Abstract

pub_date

2018-10-03 00:00:00

pages

14737

issue

1

issn

2045-2322

pii

10.1038/s41598-018-32841-0

journal_volume

8

pub_type

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