Abstract：
PURPOSE:We examined associations between substitution of red meat (total, processed and unprocessed, low fat and high fat) with poultry or fish and substitution of processed red meat with unprocessed red meat and the risk of type 2 diabetes. METHODS:A cohort of 53,163 participants from the Danish Diet, Cancer and Health study were followed for incident type 2 diabetes (6879 cases; median follow-up time 15.4 years). Diet was assessed by a validated 192-item food frequency questionnaire at baseline. Adjusted Cox proportional hazard models were used to calculate hazard ratios (HR) and 95% confidence intervals (CI) for type 2 diabetes associated with specified food substitutions of 150 g/week. RESULTS:Replacing total red meat with fish was associated with a lower risk of type 2 diabetes [HR 0.96 (95% CI 0.94, 0.99)] as was replacement of processed red meat with poultry or fish [HR poultry 0.96 (95% CI 0.93, 0.99)]; HR fish 0.94 [(95% CI 0.91, 0.97)]. Replacing low fat red meat or high fat red meat with fish was associated with a lower risk of type 2 diabetes whereas similar substitutions, with poultry, were not. Replacing processed red meat with unprocessed red meat was also associated with a lower risk of type 2 diabetes [HR 0.96 (95% CI 0.93, 0.99)]. CONCLUSIONS:Replacing processed red meat with poultry, replacing total or processed red meat with fish, and replacing processed red meat with unprocessed red meat were all associated with a lower risk of type 2 diabetes.
journal_name
Eur J Nutrjournal_title
European journal of nutritionauthors
Ibsen DB,Warberg CK,Würtz AML,Overvad K,Dahm CCdoi
10.1007/s00394-018-1820-0subject
Has Abstractpub_date
2019-10-01 00:00:00pages
2705-2712issue
7eissn
1436-6207issn
1436-6215pii
10.1007/s00394-018-1820-0journal_volume
58pub_type
杂志文章abstract：BACKGROUND:Rooibos tea (Aspalathus linearis) is commonly used for hyperactive gastrointestinal, respiratory and cardiovascular disorders. AIM OF STUDY:The aqueous extract of Rooibos tea (RT) was studied for the possible bronchodilator, antispasmodic and blood pressure lowering activities in an attempt to rationalize s...
journal_title：European journal of nutrition
pub_type： 杂志文章
doi：10.1007/s00394-006-0620-0
更新日期：2006-12-01 00:00:00
abstract：PURPOSE:To investigate whether the ingestion of olive oil having different phenolic contents influences the expression of blood pressure-related genes, involved in the renin-angiotensin-aldosterone system, in healthy humans. METHODS:A randomized, double-blind, crossover human trial with 18 healthy subjects, who ingest...
journal_title：European journal of nutrition
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00394-015-1110-z
更新日期：2017-03-01 00:00:00
abstract：BACKGROUND:Although research suggests that antioxidant supplementation can protect against exercise-induced muscle damage and oxidative stress, also delayed post-exercise muscle recovery and hindered adaptation to training were reported in the supplemented athletes. PURPOSE:The purpose of the study was to evaluate the...
journal_title：European journal of nutrition
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00394-014-0757-1
更新日期：2015-08-01 00:00:00
abstract：BACKGROUND:While naturally occurring inulin has anti-hyperlipidemic effects in animals and humans, health effects of synthetic inulin with different degrees of fructose polymerization remain poorly understood. AIM OF THE STUDY:Our study aimed at distinguishing health effects of synthetic inulin with different degrees ...
journal_title：European journal of nutrition
pub_type： 杂志文章
doi：10.1007/s00394-008-0713-z
更新日期：2008-06-01 00:00:00
abstract：INTRODUCTION:Breast cancer prevalence is growing worldwide. Many factors, such as diet and lifestyle could be determinants of the incidence of breast cancer. Coffee has been extensively studied in relation to several chronic diseases because of its multiple effects in health maintenance and its elevated consumption. We...
journal_title：European journal of nutrition
pub_type： 杂志文章
doi：10.1007/s00394-020-02180-w
更新日期：2020-12-01 00:00:00
abstract：PURPOSE:Current evidence accounts for the role of (poly)phenolic compounds in the prevention of non-communicable diseases. Detailed information on population-level intakes is required to translate these findings into recommendations. This work aimed to estimate (poly)phenol intake in the UK population using data from a...
journal_title：European journal of nutrition
pub_type： 杂志文章
doi：10.1007/s00394-018-1862-3
更新日期：2019-12-01 00:00:00
abstract：BACKGROUND:Experimentally imposed dietary restriction is known to extend the lifespan of rodents, perhaps by slowing the accumulation of oxidative damage that is thought to be one of the causes of aging. AIM OF THE STUDY:We examined the effects of restricted total food intake, and protein and calorie restriction, on D...
journal_title：European journal of nutrition
pub_type： 杂志文章
doi：10.1007/s00394-004-0520-0
更新日期：2005-08-01 00:00:00
abstract：PURPOSE:Osteoporosis is associated with both lower health-related quality of life and depression in older people. We examined the independent and combined effects of a multi-component exercise program and calcium-vitamin D3 fortified milk on health-related quality of life (HR-QoL) and depression in older men. METHODS:...
journal_title：European journal of nutrition
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00394-019-01969-8
更新日期：2020-04-01 00:00:00
abstract：INTRODUCTION:There is growing evidence that a diet low in fermentable oligosaccharides, disaccharides, monosaccharides, and polyols (FODMAP) improves symptoms in irritable bowel syndrome (IBS) patients. We aimed to retrospectively investigate the effects of this diet in Irish IBS cohort over a 12-month follow-up period...
journal_title：European journal of nutrition
pub_type： 杂志文章
doi：10.1007/s00394-019-02074-6
更新日期：2020-08-01 00:00:00
abstract：PURPOSE:Risks of dehydration and cognitive decline increase with advancing age, yet the relation between dehydration, water intake, and cognitive performance among older adults remains understudied. METHODS:Using data from the 2011-2014 cycles of the Nutrition and Health Examination Survey (NHANES), we tested if calcu...
journal_title：European journal of nutrition
pub_type： 杂志文章
doi：10.1007/s00394-019-02152-9
更新日期：2020-10-01 00:00:00
abstract：PURPOSE:Non-alcoholic fatty liver disease (NAFLD), known to be related to insulin resistance, has been the focus of intensive research efforts due to its increasing prevalence and clinical significance. Rapid eating behavior is another emerging health issue associated with insulin resistance. We aimed to clarify the co...
journal_title：European journal of nutrition
pub_type： 杂志文章
doi：10.1007/s00394-015-0851-z
更新日期：2016-02-01 00:00:00
abstract：PURPOSE:To analyze the presence of total IgA and anti-gliadin antibodies (AGA) in BM from CD mothers who follow a gluten-free diet (GFD) and from mothers on a normal gluten-containing diet (ND). METHODS:218 samples of mature milk were obtained at different months of lactation (1-6) from 83 mothers (2 or more samples p...
journal_title：European journal of nutrition
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00394-017-1476-1
更新日期：2018-08-01 00:00:00
abstract：OBJECTIVE:Epidemiologic evidence on the potential effects of dietary acid load on frailty is lacking. This cross-sectional study examined the association between dietary acid load and frailty. METHODS:This study was based on self-reported data obtained from 2176 Japanese women aged 65-94 years. Dietary acid load was c...
journal_title：European journal of nutrition
pub_type： 杂志文章
doi：10.1007/s00394-017-1449-4
更新日期：2018-06-01 00:00:00
abstract：PURPOSE:Animal and laboratory studies suggest that long-chain omega-3 (n-3) fatty acids, a type of polyunsaturated fat found in fatty fish, may protect against carcinogenesis, but human studies on dietary intake of polyunsaturated fats and fish with endometrial cancer risk show mixed results. METHODS:We evaluated the ...
journal_title：European journal of nutrition
pub_type： 杂志文章
doi：10.1007/s00394-012-0436-z
更新日期：2013-04-01 00:00:00
abstract：BACKGROUND:The association between inflammatory potential of diet and renal cancer risk has not been investigated. METHODS:In this study, we explored the association between the dietary inflammatory index (DII) and risk of renal cancer in the Iowa Women's Health Study. From 1986 to 2011, 33,817 women initially recruit...
journal_title：European journal of nutrition
pub_type： 杂志文章
doi：10.1007/s00394-017-1403-5
更新日期：2018-04-01 00:00:00
abstract：BACKGROUND:The antiatherogenic activity of pomegranate juice has been attributed to its antioxidant polyphenols. The most potent in vitro antioxidant polyphenol from this juice is the ellagitannin punicalagin. However, the bioavailability of ellagitannins, including punicalagin, has not been previously described in hum...
journal_title：European journal of nutrition
pub_type： 杂志文章
doi：10.1007/s00394-004-0461-7
更新日期：2004-08-01 00:00:00
abstract：BACKGROUND:Depression is a very common disorder in elderly, especially in those institutionalized. Nutrition could play an important role in the onset and/or progression of depression, since the intake of carbohydrates with a high glycaemic index (GI) or diets with a high glycaemic load (GL) may increase the insulin-in...
journal_title：European journal of nutrition
pub_type： 杂志文章
doi：10.1007/s00394-012-0412-7
更新日期：2013-04-01 00:00:00
abstract：BACKGROUND:DNA methylation is an important epigenetic process for transcriptional control of human genome including those genes involved in cancer initiation and progression. Clinical studies have suggested that biological explanation to the protective effect of some nutrients could be linked with the DNA methylation. ...
journal_title：European journal of nutrition
pub_type： 杂志文章
doi：10.1007/s00394-009-0010-5
更新日期：2009-08-01 00:00:00
abstract：BACKGROUND:Several factors can affect glycemic and insulinemic responses from cereal foods. Some suggested factors lowering the responses are; intact botanical structure, high amylose/high ss-glucan cereal varieties, organic acid produced during fermentation and food processes inducing retrogradation of starch. AIM OF...
journal_title：European journal of nutrition
pub_type： 杂志文章
doi：10.1007/s00394-008-0724-9
更新日期：2008-09-01 00:00:00
abstract：PURPOSE:Type 2 diabetes mellitus (T2DM) is characterized by both impaired pancreatic β-cell function (BCF) and insulin resistance. In the etiology of T2DM, BCF basically determines whether a person with a certain degree of insulin resistance develops T2DM, as β-cells are able to compensatorily increase insulin secretio...
journal_title：European journal of nutrition
pub_type： 杂志文章
doi：10.1007/s00394-018-1644-y
更新日期：2019-03-01 00:00:00
abstract：BACKGROUND:The prevalence of overweight/obesity and related manifestations such as metabolic syndrome (MetS) is increasing worldwide. High energy density diets, usually with low nutrient density, are among the main causes. Some high-quality dietary patterns like the Mediterranean diet (MedDiet) have been linked to the ...
journal_title：European journal of nutrition
pub_type： 杂志文章
doi：10.1007/s00394-019-02087-1
更新日期：2020-09-01 00:00:00
abstract：PURPOSE:Laboratory studies have suggested that vitamin D inadequacy may be implicated in development of hypertension. Evidence from epidemiologic studies remains limited. We aim to examine the prospective associations of circulating vitamin D metabolites, vitamin D receptor (VDR) gene polymorphisms, and their interacti...
journal_title：European journal of nutrition
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00394-012-0480-8
更新日期：2013-10-01 00:00:00
abstract：PURPOSE:To determine the influence of meal composition on the glycaemic impact of different carbohydrate staples, and the accuracy of "adjusted calculated meal GI" compared with "measured mixed-meal GI". METHODS:In a non-blind randomized crossover trial fasted healthy subjects consumed four dinner-type mixed meals of ...
journal_title：European journal of nutrition
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00394-018-1813-z
更新日期：2019-10-01 00:00:00
abstract：PURPOSE:Although there is good evidence showing that diets rich in medium chain fatty acids (MCFAs) have less marked obesogenic and diabetogenic effects than diets rich in long chain fatty acids (LCFAs), the role of the pro-inflammatory, medium chain fatty acid receptor (GPR84) in the aetiology of obesity and glucose i...
journal_title：European journal of nutrition
pub_type： 杂志文章
doi：10.1007/s00394-017-1456-5
更新日期：2018-08-01 00:00:00
abstract：PURPOSE:In vitro and in vivo studies suggested that flavonols, flavones, flavanones and flavan-3-ols have preventive effects on breast carcinogenesis. Epidemiological evidence about the associations between these flavonoid biomarkers and breast cancer risk is limited. This study aimed to investigate the association bet...
journal_title：European journal of nutrition
pub_type： 杂志文章
doi：10.1007/s00394-020-02331-z
更新日期：2020-07-18 00:00:00
abstract：BACKGROUND:In addition to regulating calcium homoeostasis and bone health, vitamin D influences vascular and metabolic processes including endothelial function (EF) and insulin signalling. This systematic review and meta-analysis of randomised clinical trials (RCTs) were conducted to investigate the effect of vitamin D...
journal_title：European journal of nutrition
pub_type： 杂志文章,meta分析,评审
doi：10.1007/s00394-016-1159-3
更新日期：2017-04-01 00:00:00
abstract：PURPOSE:Although several researches have demonstrated that rooibos extract has hypoglycemic effect, the role of aspalathin, a main polyphenol in the extract, remains unclear. Our aims were to find specific mechanisms for anti-diabetic action of aspalathin employing a rat skeletal muscle-derived cell line (L6 myocytes) ...
journal_title：European journal of nutrition
pub_type： 杂志文章
doi：10.1007/s00394-012-0466-6
更新日期：2013-09-01 00:00:00
abstract：BACKGROUND:Intraduodenal administration of peptone prepared from soybean beta-conglycinin (BconP) stimulates cholecystokinin (CCK) secretion from enteroendocrine cells, and suppresses food intake in rats. However, the sensing mechanism of BconP by CCK-producing cells is unknown. AIM OF THE STUDY:We investigated signal...
journal_title：European journal of nutrition
pub_type： 杂志文章
doi：10.1007/s00394-008-0764-1
更新日期：2009-03-01 00:00:00
abstract：PURPOSE:It was hypothesised that blackcurrant seed oil beneficially modulates metabolic disorders related to obesity and its complications. The study also aimed to investigate the potentially adverse effects of an unbalanced diet on the distal intestine. METHODS:Male Wistar rats were randomly assigned to four groups o...
journal_title：European journal of nutrition
pub_type： 杂志文章
doi：10.1007/s00394-014-0775-z
更新日期：2015-09-01 00:00:00
abstract：PURPOSE:Our recent study has reported that whole mung bean showed better beneficial effects on high-fat diet (HFD)-induced obesity and gut microbiota disorders when compared with the decorticated mung bean at the same intervention dose level, suggesting that the mung bean seed coat (MBC) may play a crucial role in its ...
journal_title：European journal of nutrition
pub_type： 杂志文章
doi：10.1007/s00394-020-02395-x
更新日期：2020-10-01 00:00:00
