Abstract:
INTRODUCTION:Breast cancer prevalence is growing worldwide. Many factors, such as diet and lifestyle could be determinants of the incidence of breast cancer. Coffee has been extensively studied in relation to several chronic diseases because of its multiple effects in health maintenance and its elevated consumption. We studied the relationship between coffee intake and breast cancer risk in the SUN (Seguimiento Universidad de Navarra) prospective cohort. MATERIALS AND METHODS:We evaluated 10,812 middle-aged, Spanish female university graduates from the SUN Project, initially free of breast cancer. Coffee consumption was assessed with a 136-item validated food-frequency questionnaire (FFQ). Incident breast cancer cases were confirmed by a trained oncologist using medical records and by consultation of the National Death Index. We fitted Cox regression models to assess the relationship between baseline categories of coffee consumption and the incidence of breast cancer during follow-up. We stratified the analysis by menopausal status. RESULTS:During 115,802 person-years of follow-up, 101 new cases of breast cancer were confirmed. Among postmenopausal women, more than 1 cup of coffee per day was associated with a lower incidence of breast cancer (HR 0.44; 95% confidence interval: 0.21, 0.92) in the fully adjusted model, compared to women who consumed one cup of coffee or less per day. We observed no significant differences in regard to premenopausal women. CONCLUSION:Even though the number of cases was low, slight indications of an inverse association between coffee consumption and breast cancer risk among postmenopausal women were observed. Further longitudinal studies are warranted to confirm this finding.
journal_name
Eur J Nutrjournal_title
European journal of nutritionauthors
Sánchez-Quesada C,Romanos-Nanclares A,Navarro AM,Gea A,Cervantes S,Martínez-González MÁ,Toledo Edoi
10.1007/s00394-020-02180-wsubject
Has Abstractpub_date
2020-12-01 00:00:00pages
3461-3471issue
8eissn
1436-6207issn
1436-6215pii
10.1007/s00394-020-02180-wjournal_volume
59pub_type
杂志文章abstract:BACKGROUND:Vegetables and fruits are rich sources of a variety of nutrients, including vitamins (E and C), trace minerals, and dietary fibers, and many other classes of biologically active compounds such as carotenoids and polyphenols, which are often assumed to protect against degenerative pathologies such as cardiova...
journal_title:European journal of nutrition
pub_type: 杂志文章
doi:10.1007/s00394-006-0594-y
更新日期:2006-08-01 00:00:00
abstract:PURPOSE:While the prevalence of children on vegetarian diets is assumed to be on the rise in industrialized countries, there are hardly any representative data available. In general, vegetarian diets are presumed to be healthy; nevertheless, there are concerns as to whether the dietary specifications required during in...
journal_title:European journal of nutrition
pub_type: 杂志文章,评审
doi:10.1007/s00394-017-1416-0
更新日期:2017-08-01 00:00:00
abstract:PURPOSE:We examined whether high doses of folic acid and iron supplementation in early-to-mid pregnancy affect the risk of preterm birth, low birth weight, and small for gestational age neonates, in the mother-child cohort in Crete, Greece (Rhea study). METHODS:We included 1,279 women with singleton pregnancies with c...
journal_title:European journal of nutrition
pub_type: 杂志文章
doi:10.1007/s00394-012-0339-z
更新日期:2013-02-01 00:00:00
abstract:BACKGROUND:Diet has an important role in host-microbiome interplay, which may result in intestinal permeability changes and physiopathological effects at a systemic level. Despite the importance of maternal microbiota as the main contributor to the initial microbial seeding, little is known about the effects of materna...
journal_title:European journal of nutrition
pub_type: 杂志文章
doi:10.1007/s00394-020-02337-7
更新日期:2020-07-29 00:00:00
abstract:INTRODUCTION:The objective of this paper was to evaluate the relationship between urinary concentrations of InsP6, bone mass loss and risk fracture in postmenopausal women. MATERIALS AND METHODS:A total of 157 postmenopausal women were included in the study: 70 had low (≤0.76 μM), 42 intermediate (0.76-1.42 μM) and 45...
journal_title:European journal of nutrition
pub_type: 临床试验,杂志文章
doi:10.1007/s00394-012-0377-6
更新日期:2013-03-01 00:00:00
abstract:PURPOSE:We examined associations between substitution of red meat (total, processed and unprocessed, low fat and high fat) with poultry or fish and substitution of processed red meat with unprocessed red meat and the risk of type 2 diabetes. METHODS:A cohort of 53,163 participants from the Danish Diet, Cancer and Heal...
journal_title:European journal of nutrition
pub_type: 杂志文章
doi:10.1007/s00394-018-1820-0
更新日期:2019-10-01 00:00:00
abstract:BACKGROUND:The study of vitamin D status at population level gained relevance since vitamin D deficiency was recently suggested to trigger chronic disease. AIM OF THE STUDY:We aimed to describe vitamin D status, its association with bone and mineral metabolism and risk factors for deficiency in adults over 40 years in...
journal_title:European journal of nutrition
pub_type: 杂志文章
doi:10.1007/s00394-008-0756-1
更新日期:2009-02-01 00:00:00
abstract:OBJECTIVE:Impaired insulin sensitivity (SI) and β-cell function are the two main causes of type 2 diabetes (T2D) and are related to low-grade inflammation status. Trivalent chromium has shown to improve SI in our previous study. This might be due to the ability of decreasing interleukin-6 (IL-6) and tumor necrosis fact...
journal_title:European journal of nutrition
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00394-013-0508-8
更新日期:2014-02-01 00:00:00
abstract:PURPOSE:The optimal health benefits of curcumin are limited by its low solubility in water and corresponding poor intestinal absorption. Cyclodextrins (CD) can form inclusion complexes on a molecular basis with lipophilic compounds, thereby improving aqueous solubility, dispersibility, and absorption. In this study, we...
journal_title:European journal of nutrition
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1007/s00394-016-1376-9
更新日期:2018-04-01 00:00:00
abstract:BACKGROUND:DNA methylation is an important epigenetic process for transcriptional control of human genome including those genes involved in cancer initiation and progression. Clinical studies have suggested that biological explanation to the protective effect of some nutrients could be linked with the DNA methylation. ...
journal_title:European journal of nutrition
pub_type: 杂志文章
doi:10.1007/s00394-009-0010-5
更新日期:2009-08-01 00:00:00
abstract:PURPOSE:To assess the effectiveness of a dietary intervention combined with fortified dairy products on bone metabolism and bone mass indices in postmenopausal women. METHODS:Forty postmenopausal women (55-65 years old) were equally randomized into a dietary group (DG), receiving daily and for 30 months, 1,200 mg of c...
journal_title:European journal of nutrition
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00394-010-0142-7
更新日期:2011-08-01 00:00:00
abstract:PURPOSE:Although there is good evidence showing that diets rich in medium chain fatty acids (MCFAs) have less marked obesogenic and diabetogenic effects than diets rich in long chain fatty acids (LCFAs), the role of the pro-inflammatory, medium chain fatty acid receptor (GPR84) in the aetiology of obesity and glucose i...
journal_title:European journal of nutrition
pub_type: 杂志文章
doi:10.1007/s00394-017-1456-5
更新日期:2018-08-01 00:00:00
abstract:AIM:To evaluate the preventive and therapeutic effects of Lactobacilluscasei Zhang on impaired glucose tolerance (IGT) by using fructose-induced hyperinsulinemia rats. METHODS:Rats were fed 25 % fructose solution for hyperinsulinemia with L.casei Zhang for prevention or therapy. Serum levels of insulin, glucagon-like ...
journal_title:European journal of nutrition
pub_type: 杂志文章
doi:10.1007/s00394-013-0519-5
更新日期:2014-02-01 00:00:00
abstract:PURPOSE:Pomegranate fruit, Punica granatum L. (Punicaceae), and its constituents have been shown to inhibit inflammation. In this study, we aimed to assess the effects of freeze-dried pomegranate (PWE) on PGE2 production in IL-1β-stimulated SK-N-SH cells. METHODS:An enzyme immunoassay (EIA) was used to measure prostag...
journal_title:European journal of nutrition
pub_type: 杂志文章
doi:10.1007/s00394-015-0984-0
更新日期:2016-06-01 00:00:00
abstract:BACKGROUND:Antioxidant defence has been reported to decrease, and oxidative stress to increase, after oral glucose loading in both normal and diabetic subjects. If confirmed in normal subjects, glucose-induced antioxidant depletion has important implications for health in relation to the modern, sugar-rich diet. AIM O...
journal_title:European journal of nutrition
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1007/s00394-004-0518-7
更新日期:2005-06-01 00:00:00
abstract:PURPOSE:Menopause disturbs energy, glucose, and lipid metabolisms and changes the composition of the gut microbiota, but dietary fibers without phytoestrogens may ameliorate menopausal metabolic disorders. The objective of the present study was to assess whether consuming the prebiotics chitosan and citrus pectin can i...
journal_title:European journal of nutrition
pub_type: 杂志文章
doi:10.1007/s00394-020-02382-2
更新日期:2020-09-10 00:00:00
abstract:PURPOSE:Chronic sugar-sweetened beverage (SSB) consumption is associated with obesity and type 2 diabetes mellitus (T2DM). Hyperglycaemia contributes to metabolic alterations observed in T2DM, such as reduced oxidative capacity and elevated glycolytic and lipogenic enzyme expressions in skeletal muscle tissue. We aimed...
journal_title:European journal of nutrition
pub_type: 临床试验,杂志文章
doi:10.1007/s00394-012-0401-x
更新日期:2013-04-01 00:00:00
abstract:PURPOSE:To estimate total sodium (Na) and potassium (K) intake using non-fasting morning urine specimens among Lebanese elementary (6-10 year old) schoolchildren. METHOD:A national cross-sectional study was conducted. A multistage cluster sampling procedure was used to select a representative sample of 1403 healthy ch...
journal_title:European journal of nutrition
pub_type: 杂志文章
doi:10.1007/s00394-016-1164-6
更新日期:2017-04-01 00:00:00
abstract:BACKGROUND:Intraduodenal administration of peptone prepared from soybean beta-conglycinin (BconP) stimulates cholecystokinin (CCK) secretion from enteroendocrine cells, and suppresses food intake in rats. However, the sensing mechanism of BconP by CCK-producing cells is unknown. AIM OF THE STUDY:We investigated signal...
journal_title:European journal of nutrition
pub_type: 杂志文章
doi:10.1007/s00394-008-0764-1
更新日期:2009-03-01 00:00:00
abstract:PURPOSE:The potential association between endometriosis and coffee/caffeine consumption has been analysed in several epidemiological studies. In order to establish whether caffeine influences the risk of endometriosis, we provide to summarize the evidence from published studies on this issue. METHODS:We performed a me...
journal_title:European journal of nutrition
pub_type: 杂志文章,meta分析
doi:10.1007/s00394-014-0662-7
更新日期:2014-10-01 00:00:00
abstract:PURPOSE:Osteoporosis is associated with both lower health-related quality of life and depression in older people. We examined the independent and combined effects of a multi-component exercise program and calcium-vitamin D3 fortified milk on health-related quality of life (HR-QoL) and depression in older men. METHODS:...
journal_title:European journal of nutrition
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00394-019-01969-8
更新日期:2020-04-01 00:00:00
abstract:BACKGROUND:Neurodevelopmental effects of omega-3 fatty acids and mercury from fish consumption have been characterized in children. In contrast, neurobehavioral outcomes associated with fish are not well studied in adults. OBJECTIVE:This study of avid seafood consumers on Long Island (NY, USA) sought to define associa...
journal_title:European journal of nutrition
pub_type: 杂志文章
doi:10.1007/s00394-015-0890-5
更新日期:2016-03-01 00:00:00
abstract:PURPOSE:A meal replacement may be an effective strategy in the management of obesity to increase antioxidant intake, attenuating oxidative stress and inflammation. In the present study, we investigated the efficacy of a new nutritional supplement to reduce metabolic risk parameters in obese women. METHODS:In a randomi...
journal_title:European journal of nutrition
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1007/s00394-013-0598-3
更新日期:2014-04-01 00:00:00
abstract:PURPOSE:To assess the effect of medium-chain fatty acid (MCFA)-rich mustard oil and polyunsaturated fatty acid (PUFA)-rich mustard oil on erythrocyte membrane composition and osmotic fragility in normal and hypercholesterolemic rats. METHOD:Membrane composition was analyzed using standard kits. Osmotic fragility was d...
journal_title:European journal of nutrition
pub_type: 杂志文章
doi:10.1007/s00394-010-0150-7
更新日期:2011-09-01 00:00:00
abstract:PURPOSE:Observational studies have suggested that polyunsaturated fatty acids (PUFAs) may decrease Alzheimer's disease (AD) risk. In the present study, we examined this hypothesis using a Mendelian randomization analysis. METHODS:We used summary statistics data for single-nucleotide polymorphisms associated with plasm...
journal_title:European journal of nutrition
pub_type: 杂志文章
doi:10.1007/s00394-019-02126-x
更新日期:2020-06-01 00:00:00
abstract:PURPOSE:Accumulating evidence suggests that inhibitors of aldose reductase (AR) may prevent hyperglycemia-induced long-term complications in diabetes mellitus. In the present study, we evaluated the AR inhibitory potential of ethanolic (EtOH) extracts from 22 seaweed species. METHODS:AR inhibitory activities of the se...
journal_title:European journal of nutrition
pub_type: 杂志文章
doi:10.1007/s00394-013-0521-y
更新日期:2014-02-01 00:00:00
abstract:PURPOSE:Dietary polyphenols have been studied for their potential effects on metabolic disorders, but studies on risk of hypertension are scarce. This study aimed to test the association between total and individual classes of dietary polyphenols and incidence of hypertension in the Polish arm of the Health, Alcohol an...
journal_title:European journal of nutrition
pub_type: 杂志文章
doi:10.1007/s00394-017-1438-7
更新日期:2018-06-01 00:00:00
abstract:PURPOSE:Diarrhea-predominant irritable bowel syndrome (IBS-D) is a common functional gastrointestinal disorder. Probiotics and synbiotics have been shown to improve symptoms of IBS, although mechanisms of action are currently not understood. METHODS:We investigated the effects of a 4-week oral synbiotic treatment (OMN...
journal_title:European journal of nutrition
pub_type: 杂志文章
doi:10.1007/s00394-018-1826-7
更新日期:2019-10-01 00:00:00
abstract:PURPOSE:Berries and mixed berry products exert acute effects on postprandial glycaemia and insulinemia, but very few berries have been studied, and primarily in normal weight subjects. Sea buckthorn and strawberry are compositionally widely different berries and may likely produce different responses. The effects of st...
journal_title:European journal of nutrition
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00394-017-1550-8
更新日期:2018-12-01 00:00:00
abstract:PURPOSE:Fruit and vegetable intake has been inversely associated with the risk of hypertension; however, there is inconsistent evidence on the long-term association. Given this gap in the literature, it is necessary to identify evidence from large prospective studies, especially in China, where insufficient evidence ex...
journal_title:European journal of nutrition
pub_type: 杂志文章
doi:10.1007/s00394-018-1687-0
更新日期:2018-10-01 00:00:00