Competency Based Approach to Community Health (COACH): The methods of a family-centered, community-based, individually adaptive obesity randomized trial for pre-school child-parent pairs.

abstract：:The prevalence of obesity is high resulting from chronic imbalances between energy intake and expenditure. On the expenditure side, regular exercise is associated with health benefits, including enhanced brain function. The benefits of exercise are not immediate and require persistence to be realized. Brain regions as...

journal_title：Contemporary clinical trials

authors： Herrmann SD,Martin LE,Breslin FJ,Honas JJ,Willis EA,Lepping RJ,Gibson CA,Befort CA,Lambourne K,Burns JM,Smith BK,Sullivan DK,Washburn RA,Yeh HW,Donnelly JE,Savage CR

更新日期：2014-01-01 00:00:00

abstract：:Interactive voice response (IVR) technology is a robust method of data collection that has been underutilized in behavioral medicine and clinical pharmacotherapy research. While it is clear that there is an increasing interest in this technology, published research in the medical field has not described its implementa...

journal_title：Contemporary clinical trials

authors： Abu-Hasaballah K,James A,Aseltine RH Jr

更新日期：2007-09-01 00:00:00

abstract：BACKGROUND:We evaluated the association of demographic and clinical characteristics with participation in an epidemiologic study of diabetes mellitus among youth. METHODS:SEARCH for Diabetes in Youth is a multicenter study of physician-diagnosed diabetes in youth under the age of 20 comprising a surveillance and a coh...

journal_title：Contemporary clinical trials

authors： Liese AD,Liu L,Davis C,Standiford D,Waitzfelder B,Dabelea D,Bell R,Williams D,Imperatore G,Lawrence JM

更新日期：2008-11-01 00:00:00

abstract：BACKGROUND:Suboptimal diet and inactive lifestyle are among the most prevalent preventable causes of premature death. Interventions that target multiple behaviors are potentially efficient; however the optimal way to initiate and maintain multiple health behavior changes is unknown. OBJECTIVE:The Make Better Choices 2...

journal_title：Contemporary clinical trials

authors： Pellegrini CA,Steglitz J,Johnston W,Warnick J,Adams T,McFadden HG,Siddique J,Hedeker D,Spring B

更新日期：2015-03-01 00:00:00

abstract：OBJECTIVE:To describe the study protocol of the Multimedia Self-Management (MSM) intervention to prepare patients and family caregivers (FCGs) for lung cancer surgery. DESIGN:The study is a five-year, single site, randomized controlled trial of 160 lung cancer surgery FCG and patient dyads (320 total participants), co...

journal_title：Contemporary clinical trials

authors： Sun V,Raz DJ,Erhunmwunsee L,Ruel N,Carranza J,Prieto R,Ferrell B,Krouse RS,McCorkle R,Kim JY

更新日期：2019-08-01 00:00:00

abstract：:Home-based telemedicine (HBT) is a validated method of evidence-based treatment delivery for posttraumatic stress disorder (PTSD), and justification for its use has centered on closing gaps related to provider availability and distance to treatment centers. However, another potential use of HBT may be to overcome barr...

journal_title：Contemporary clinical trials

authors： Gilmore AK,Davis MT,Grubaugh A,Resnick H,Birks A,Denier C,Muzzy W,Tuerk P,Acierno R

更新日期：2016-05-01 00:00:00

abstract：:Slow or insufficient enrollment in clinical research and a high demand for research participants raises questions about the need for and use of incentives to participate, including payment. Much of the available literature on payment to research participants focuses on ethical concerns, and rarely addresses guidelines...

journal_title：Contemporary clinical trials

authors： Dominguez D,Jawara M,Martino N,Sinaii N,Grady C

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:Although people who inject drugs (PWID) having the highest incidence and prevalence of hepatitis C virus (HCV) in the US, HCV treatment is rarely provided to PWID due to assumptions about poor adherence and reinfection risk. As direct-acting antiviral agents (DAAs) have achieved sustained virologic response ...

journal_title：Contemporary clinical trials

authors： Litwin AH,Jost J,Wagner K,Heo M,Karasz A,Feinberg J,Kim AY,Lum PJ,Mehta SH,Taylor LE,Tsui JI,Pericot-Valverde I,Page K,HERO Study Group.

更新日期：2019-12-01 00:00:00

abstract：:Ethically sound clinical research requires that prospective study participants provide voluntary informed consent before any study procedures begin. The original intent was to provide the participant with clear, accurate information about study specifics (e.g., risks/benefits) to aid in the decision to participate. Br...

journal_title：Contemporary clinical trials

authors： Lentz J,Kennett M,Perlmutter J,Forrest A

更新日期：2016-07-01 00:00:00

abstract：BACKGROUND:Obesity, a disorder associated with a myriad of comorbidities, is increasing at an alarming rate around the world. Given that pharmacotherapy has limited available options and that bariatric surgery is reserved for those who are morbidly obese or who have significant comorbidities, the most common approach t...

journal_title：Contemporary clinical trials

authors： Burke LE,Choo J,Music E,Warziski M,Styn MA,Kim Y,Sevick MA

更新日期：2006-02-01 00:00:00

abstract：BACKGROUND:Hypertension disproportionately affects African Americans compared to whites, and it is the single most common explanation for the disparity in mortality between African Americans and whites. Adherence with antihypertensive medications can help reduce risk of negative hypertension-related outcomes. Motivatio...

journal_title：Contemporary clinical trials

authors： Ogedegbe G,Schoenthaler A,Richardson T,Lewis L,Belue R,Espinosa E,Spencer J,Allegrante JP,Charlson ME

更新日期：2007-02-01 00:00:00

abstract：BACKGROUND:Currently, there is no consensus regarding the best treatment option in recurrent haemorrhoidal disease (HD), due to a lack of solid evidence. The Napoleon trial aims to provide high-level evidence on the comparative effectiveness and cost-effectiveness of repeat rubber band ligation (RBL) versus sutured muc...

journal_title：Contemporary clinical trials

authors： Kuiper SZ,Dirksen CD,Kimman ML,Van Kuijk SMJ,Van Tol RR,Muris JWM,Watson AJM,Maessen JMC,Melenhorst J,Breukink SO,Napoleon Trial Study Group.

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND:Current guidelines recommend behavioral intervention to achieve a modest weight loss (e.g., 3-5%) as a first-line obesity treatment. Online behavioral obesity treatment, delivered via the Rx Weight Loss (RxWL) program, produces clinically significant initial weight losses. However, the program's pragmatic ut...

journal_title：Contemporary clinical trials

authors： Espel-Huynh HM,Wing RR,Goldstein CM,Thomas JG

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND:Mindfulness-based relapse prevention (MBRP) is a method that combines cognitive behavioral relapse prevention with mindfulness practice. Research suggests that MBRP can effectively reduce withdrawal/craving in people with substance use disorder (SUD). An important part of MBRP is to practice mindfulness medi...

journal_title：Contemporary clinical trials

authors： Chen XJ,Wang DM,Zhou LD,Winkler M,Pauli P,Sui N,Li YH

更新日期：2018-07-01 00:00:00

abstract：:The Medication Adherence and BP Control Trial (ABC Trial) is a randomized, controlled, multi-site, medication adherence and blood pressure (BP) control trial in an economically disadvantaged and multi-cultural population of hypertensive patients followed in primary care practices. To date, no other such trial has been...

journal_title：Contemporary clinical trials

authors： Gerin W,Tobin JN,Schwartz JE,Chaplin W,Rieckmann N,Davidson KW,Goyal TM,Jhalani J,Cassells A,Feliz K,Khalida C,Diaz-Gloster M,Ogedegbe G

更新日期：2007-07-01 00:00:00

abstract：PURPOSE:By 2020, 70% of people living with HIV in the United States will be greater than 50 years of age. As many as 37% of sexually active older people living with HIV (OPLWH) engage in HIV transmission sexual behaviors. In spite of repeated calls for secondary prevention interventions to reduce condomless sex in OPLW...

journal_title：Contemporary clinical trials

authors： Kahler J,Heckman TG,Shen Y,Huckans MS,Feldstein Ewing SW,Parsons JT,Phelps A,Sutton M,Holloway J,Lovejoy TI

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:The addition of specialty palliative care to standard oncology care improves outcomes for patients with advanced cancer and their caregivers, but many lack access to specialty care services. Primary palliative care-meaning basic palliative care services provided by clinicians who are not palliative care spec...

journal_title：Contemporary clinical trials

authors： Becker CL,Arnold RM,Park SY,Rosenzweig M,Smith TJ,White DB,Smith KJ,Schenker Y

更新日期：2017-03-01 00:00:00

abstract：:Pediatric primary care is an important setting in which to address obesity prevention, yet relatively few interventions have been evaluated and even fewer have been shown to be effective. The development and evaluation of cost-effective approaches to obesity prevention that leverage opportunities of direct access to f...

journal_title：Contemporary clinical trials

authors： Sherwood NE,Levy RL,Langer SL,Senso MM,Crain AL,Hayes MG,Anderson JD,Seburg EM,Jeffery RW

更新日期：2013-09-01 00:00:00

abstract：BACKGROUND:Despite widespread use of learning collaboratives in health care, few randomized trials have evaluated their effectiveness. The primary aim of this cluster randomized implementation trial is to evaluate the effectiveness of a virtual learning collaborative (VLC) in the implementation of a lifestyle intervent...

journal_title：Contemporary clinical trials

authors： Aschbrenner KA,Pratt SI,Bond GR,Zubkoff L,Naslund JA,Jue K,Williams G,Kinney A,Cohen MJ,Godfrey MM,Bartels SJ

更新日期：2019-09-01 00:00:00

abstract：:Modified Zelen's approach is a randomization technique useful in multi-center trials where balance in treatment assignments within a center is desired. It has great balancing properties in a study with equal allocation to several treatment arms. This technique can also be used in studies with unequal allocation, where...

journal_title：Contemporary clinical trials

authors： Kuznetsova OM,Tymofyeyev Y

更新日期：2011-11-01 00:00:00

abstract：:We describe an emergency department (ED)-based, Latino patient focused, unblinded, randomized controlled trial to empirically test if automated bilingual computerized alcohol screening and brief intervention (AB-CASI), a digital health tool, is superior to standard care (SC) on measures of alcohol consumption, alcohol...

journal_title：Contemporary clinical trials

authors： Vaca FE,Dziura J,Abujarad F,Pantalon MV,Hsiao A,Field CA,D'Onofrio G

更新日期：2020-10-01 00:00:00

abstract：:Although progress has been made to elucidate the effects of exercise as a strategy for reducing obesity and related cardiometabolic risk factors, the specific exercise exposures required to achieve optimal benefit continue to be the source of considerable uncertainty and debate. Despite the inference of a dose-depende...

journal_title：Contemporary clinical trials

authors： Ross R,Hudson R,Day AG,Lam M

更新日期：2013-01-01 00:00:00

abstract：:Lumbar spinal stenosis is a common degenerative disorder of the spine in elderly patients that can be effectively treated with decompression surgery in some patients. Radiological findings in the diagnostic work-up of the patients do not always correlate well with clinical symptoms, and guidance about when to proceed ...

journal_title：Contemporary clinical trials

authors： Staub LP,Barz T,Melloh M,Lord SJ,Chatfield M,Bossuyt PM

更新日期：2011-05-01 00:00:00

abstract：:Knee osteoarthritis (OA) is a leading cause of late life pain and disability, and non-Hispanic black (NHB) adults experience greater OA-related pain and disability than non-Hispanic whites (NHWs). Recent evidence implicates psychosocial stress, cognitive-attentional processes, and altered central pain processing as co...

journal_title：Contemporary clinical trials

authors： Fillingim RB,Woods AJ,Ahn H,Wu SS,Redden DT,Lai S,Deshpande H,Deutsch G,Sibille KT,Staud R,Zeidan F,Goodin BR

更新日期：2020-11-01 00:00:00

abstract：:Transitional care programs have been widely used to reduce readmissions and improve the quality and safety of the handoff process between hospital and outpatient providers. Very little is known about effective transitional care interventions among patients who are uninsured or with Medicaid. This paper describes the d...

journal_title：Contemporary clinical trials

authors： Schaeffer C,Teter C,Finch EA,Hurt C,Keeter MK,Liss DT,Rogers A,Sheth A,Ackermann R

更新日期：2018-02-01 00:00:00

abstract：:Determining the quality of a randomized clinical trial (RCT) is necessary for decision-makers to determine the believability and applicability of the trial findings. Issues that are likely to affect the utility of RCT evidence include issues of bias, random error and applicability. In this article we focus primarily o...

journal_title：Contemporary clinical trials

authors： Mills EJ,Ayers D,Chou R,Thorlund K

更新日期：2015-11-01 00:00:00

abstract：BACKGROUND:Functional dyspepsia (FD) is a common problem affecting up to 10-25% of individuals. FD accounts for significant health care costs and affects quality of life but has no definitive treatment. OBJECTIVES:The Functional Dyspepsia Treatment Trial (FDTT) aims to test whether treatment with an antidepressant (am...

journal_title：Contemporary clinical trials

authors： Talley NJ,Locke GR 3rd,Herrick LM,Silvernail VM,Prather CM,Lacy BE,DiBaise JK,Howden CW,Brenner DM,Bouras EP,El-Serag HB,Abraham BP,Moayyedi P,Zinsmeister AR

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND:Anxiety and mood disorders involve a high disease burden and are associated with high economic costs. A stepped-care approach intervention and abbreviated diagnostic method are assumed to increase effectiveness and efficiency of the mental healthcare and are expected to reduce economic costs. METHODS:Presen...

journal_title：Contemporary clinical trials

authors： Meuldijk D,Carlier IV,van Vliet IM,van den Akker-Marle ME,Zitman FG

更新日期：2012-09-01 00:00:00

abstract：:We report here on the use of interactive telephone technology for collecting longitudinal data in a large randomized non-blinded parallel trial. Data were primarily collected via an automated interactive telephone system which enabled data to be downloaded by researchers periodically via a secure website. Alternative ...

journal_title：Contemporary clinical trials

authors： Russell C,Howel D,Ward-Platt MP,Ball HL

更新日期：2012-03-01 00:00:00

abstract：:An instrumental variable (IV) estimator has been widely used to estimate causal effects among compliers in randomized trials with noncompliance. The estimator of complier average treatment effect can be expressed as a ratio of two unbiased estimators but the ratio estimator is not unbiased. The bias of IV estimator ca...

journal_title：Contemporary clinical trials

authors： Chan KC

更新日期：2012-07-01 00:00:00