Mindfulness-based relapse prevention combined with virtual reality cue exposure for methamphetamine use disorder: Study protocol for a randomized controlled trial.

abstract：BACKGROUND:Functional dyspepsia (FD) is a common problem affecting up to 10-25% of individuals. FD accounts for significant health care costs and affects quality of life but has no definitive treatment. OBJECTIVES:The Functional Dyspepsia Treatment Trial (FDTT) aims to test whether treatment with an antidepressant (am...

journal_title：Contemporary clinical trials

authors： Talley NJ,Locke GR 3rd,Herrick LM,Silvernail VM,Prather CM,Lacy BE,DiBaise JK,Howden CW,Brenner DM,Bouras EP,El-Serag HB,Abraham BP,Moayyedi P,Zinsmeister AR

更新日期：2012-05-01 00:00:00

abstract：:Researchers have long sought to find combinations of cancer drugs that might achieve synergy. However, while observed in some preclinical tumor models, synergistic effects are rarely seen in clinical trials. In fact, growing evidence in clinical trial data shows that the treatment effect of most approved combination t...

journal_title：Contemporary clinical trials

authors： Chen C,Liu F,Ren Y,Suttner L,Sun Z,Shentu Y,Schmidt EV

更新日期：2020-11-01 00:00:00

abstract：BACKGROUND:Intake of sugar-sweetened beverages is associated with overweight in observational studies. A possible explanation is that liquid sugars do not satiate and that their intake is not compensated by reduced caloric intake from other foods. However, evidence from intervention studies for this hypothesis is incon...

journal_title：Contemporary clinical trials

authors： de Ruyter JC,Olthof MR,Kuijper LD,Katan MB

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Many of the health behaviors known to contribute to cardiometabolic risk and disease (CMRD), including physical activity, diet, sleep, and screen time, begin during childhood. Given the population-wide burden of CMRD, novel ways of assessing risk and providing feedback to support behavior change are needed. ...

journal_title：Contemporary clinical trials

authors： Oreskovic NM,Fletcher R,Sharifi M,Knutsen JD,Chilingirian A,Taveras EM

更新日期：2016-07-01 00:00:00

abstract：BACKGROUND:Management of asthma involves adherence to medication regimens. Assessing adherence is difficult for health care providers and researchers. Self-reported medication use is subjective, so objective methods of data collection for medication use are frequently used in asthma research. The aim of this project is...

journal_title：Contemporary clinical trials

authors： Mudd KE,Bollinger ME,Hsu VD,Manning A,Tsoukleris MG,Butz AM

更新日期：2008-01-01 00:00:00

abstract：:Osteoarthritis (OA) is the most common chronic condition and principal cause of disability among older adults. The current obesity epidemic has contributed to this high prevalence rate. Fortunately both OA symptoms and obesity can be ameliorated through lifestyle modifications. Physical activity (PA) combined with wei...

journal_title：Contemporary clinical trials

authors： Smith-Ray RL,Fitzgibbon ML,Tussing-Humphreys L,Schiffer L,Shah A,Huber GM,Braunschweig C,Campbell RT,Hughes SL

更新日期：2014-03-01 00:00:00

abstract：INTRODUCTION:Focal ablation therapy is playing an increasing role in oncology and may reduce the toxicity of current surgical treatments while achieving adequate oncological benefit. Irreversible electroporation (IRE) has been proposed to be tissue-selective with potential advantages compared with current thermal-ablat...

journal_title：Contemporary clinical trials

authors： Wendler JJ,Porsch M,Nitschke S,Köllermann J,Siedentopf S,Pech M,Fischbach F,Ricke J,Schostak M,Liehr UB

更新日期：2015-07-01 00:00:00

abstract：:This paper proposes a method for balancing prognostic variables between treatment and control groups in design of clinical trials. It assumes that some of prognostic variables are continuous and others are categorical and that they are independently distributed. The proposed method uses the Kullback-Leibler divergence...

journal_title：Contemporary clinical trials

authors： Endo A,Nagatani F,Hamada C,Yoshimura I

更新日期：2006-10-01 00:00:00

abstract：BACKGROUND:Lower extremity peripheral arterial disease (PAD) is a public health problem and many patients with PAD experience claudication despite adequate medical and/or surgical management. Mobilization of endogenous progenitor cells using Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) is a novel therapeut...

journal_title：Contemporary clinical trials

authors： Mehta A,Mavromatis K,Ko YA,Rogers SC,Dhindsa DS,Goodwin C,Patel R,Martini MA,Prasad M,Mokhtari A,Hesaroieh IG,Frohwein SC,Kutner MH,Harzand A,Wells BJ,Duwayri Y,Alabi O,Rajani RR,Brewster LP,Waller EK,Quyyumi AA

更新日期：2020-04-01 00:00:00

abstract：:Although progress has been made to elucidate the effects of exercise as a strategy for reducing obesity and related cardiometabolic risk factors, the specific exercise exposures required to achieve optimal benefit continue to be the source of considerable uncertainty and debate. Despite the inference of a dose-depende...

journal_title：Contemporary clinical trials

authors： Ross R,Hudson R,Day AG,Lam M

更新日期：2013-01-01 00:00:00

abstract：PURPOSE:Black breast cancer survivors have high rates of obesity and low physical activity levels. Little is known about the acceptability and feasibility of interventions in this population. OBJECTIVE:A two-arm RCT was launched to assess the efficacy of a culturally targeted 12-week multimodal lifestyle intervention ...

journal_title：Contemporary clinical trials

authors： Sheppard VB,Hicks J,Makambi K,Hurtado-de-Mendoza A,Demark-Wahnefried W,Adams-Campbell L

更新日期：2016-01-01 00:00:00

abstract：:In order to evaluate strategies to reduce HIV transmission through breast milk and optimize both maternal and infant health among HIV-infected women and their infants, we designed and implemented a large, randomized clinical trial in Lilongwe, Malawi. The development of protocols for large, randomized clinical trials ...

journal_title：Contemporary clinical trials

authors： van der Horst C,Chasela C,Ahmed Y,Hoffman I,Hosseinipour M,Knight R,Fiscus S,Hudgens M,Kazembe P,Bentley M,Adair L,Piwoz E,Martinson F,Duerr A,Kourtis A,Loeliger AE,Tohill B,Ellington S,Jamieson D,Breastfeeding, Ant

更新日期：2009-01-01 00:00:00

abstract：:Competency-Based Approaches to Community Health (COACH) is a randomized controlled trial of a family-centered, community-based, and individually-tailored behavioral intervention for childhood obesity among Latino pre-school children. COACH focuses on improving personal agency for health behavior change by tailoring co...

journal_title：Contemporary clinical trials

authors： Heerman WJ,Burgess LE,Escarfuller J,Teeters L,Slesur L,Liu J,Qi A,Samuels LR,Singer-Gabella M

更新日期：2018-10-01 00:00:00

abstract：INTRODUCTION:Robotic assistance during laparoscopic surgery for pelvic organ prolapse rapidly disseminated across the United States without level I data to support its benefit over traditional open and laparoscopic approaches [1]. This manuscript describes design and methodology of the Abdominal Colpopexy: Comparison o...

journal_title：Contemporary clinical trials

authors： Mueller ER,Kenton K,Tarnay C,Brubaker L,Rosenman A,Smith B,Stroupe K,Bresee C,Pantuck A,Schulam P,Anger JT

更新日期：2012-09-01 00:00:00

abstract：:The fraction of patients who respond to treatment and the duration of response in the subset of responding patients are commonly evaluated in oncology trials of cytotoxic compounds. While formal, comparative analysis of the fraction of patients responding to treatment is straightforward in a randomised trial, analyses...

journal_title：Contemporary clinical trials

authors： Ellis S,Carroll KJ,Pemberton K

更新日期：2008-07-01 00:00:00

abstract：BACKGROUND:Low back pain (LBP) is one of the most common reasons for seeking medical care. Manipulative therapies are a common treatment for LBP. Few studies have compared the effectiveness of different types of manipulative therapies. Moreover, the physiologic mechanisms underlying these treatments are not fully under...

journal_title：Contemporary clinical trials

authors： Clark BC,Russ DW,Nakazawa M,France CR,Walkowski S,Law TD,Applegate M,Mahato N,Lietkam S,Odenthal J,Corcos D,Hain S,Sindelar B,Ploutz-Snyder RJ,Thomas JS

更新日期：2018-07-01 00:00:00

abstract：BACKGROUND:Medicaid recipients with serious mental illness die 25-30 years earlier than people in the general population due to health conditions that are modifiable through lifestyle changes. Cardiovascular diseases from excess weight, smoking, and sedentary lifestyle contribute substantially to this life expectancy d...

journal_title：Contemporary clinical trials

authors： Pratt SI,Brunette MF,Wolfe R,Scherer EA,Xie H,Bartels S,Ferron JC,Capuchino K

更新日期：2019-06-01 00:00:00

abstract：:Determining the quality of a randomized clinical trial (RCT) is necessary for decision-makers to determine the believability and applicability of the trial findings. Issues that are likely to affect the utility of RCT evidence include issues of bias, random error and applicability. In this article we focus primarily o...

journal_title：Contemporary clinical trials

authors： Mills EJ,Ayers D,Chou R,Thorlund K

更新日期：2015-11-01 00:00:00

abstract：BACKGROUND:Extended-release naltrexone (XR-NTX, Vivitrol; Alkermes Inc.) is an injectable monthly sustained-release mu opioid receptor antagonist. XR-NTX is a potentially effective intervention for opioid use disorders and as relapse prevention among criminal justice system (CJS) populations. METHODS:This 5-site open-...

journal_title：Contemporary clinical trials

authors： Lee JD,Friedmann PD,Boney TY,Hoskinson RA Jr,McDonald R,Gordon M,Fishman M,Chen DT,Bonnie RJ,Kinlock TW,Nunes EV,Cornish JW,O'Brien CP

更新日期：2015-03-01 00:00:00

abstract：INTRODUCTION:In promoting the health of chronically ill children, the hospital should help children cope both medically and psychosocially with their disease. The University Children's Hospital of Nancy proposes adapted physical activity for hospitalized children, but the practice during hospitalization is not well dev...

journal_title：Contemporary clinical trials

authors： Speyer E,Vuillemin A,Herbinet A,Chastagner P,Briançon S

更新日期：2010-03-01 00:00:00

abstract：BACKGROUND:This paper reports the protocol of a randomised, double-blind, placebo-controlled study to test the efficacy, safety, and tolerability of lubiprostone (LUB) vs. placebo on suppressing gut permeability in non-alcoholic fatty liver disease (NAFLD) patients with constipation. NAFLD, including non-alcoholic stea...

journal_title：Contemporary clinical trials

authors： Kessoku T,Imajo K,Kobayashi T,Honda Y,Kato T,Ogawa Y,Tomeno W,Kato S,Higurashi T,Yoneda M,Kirikoshi H,Kubota K,Taguri M,Yamanaka T,Usuda H,Wada K,Saito S,Nakajima A

更新日期：2018-06-01 00:00:00

abstract：:Although therapeutic treatments exist for substance use disorder (SUD), about half of individuals who enter treatment leave early and relapse to substance use. Early dropout from residential treatment places individuals at risk of relapse, and women in SUD residential treatment represent a vulnerable population. Evide...

journal_title：Contemporary clinical trials

authors： Amaro H,Black DS

更新日期：2017-11-01 00:00:00

abstract：INTRODUCTION:Excessive recreational screen time (i.e., screen use for entertainment) is a global public health issue associated with adverse mental and physical health outcomes. Considering the growing popularity of screen-based recreation in adolescents, there is a need to identify effective strategies for reducing sc...

journal_title：Contemporary clinical trials

authors： Babic MJ,Morgan PJ,Plotnikoff RC,Lonsdale C,Eather N,Skinner G,Baker AL,Pollock E,Lubans DR

更新日期：2015-01-01 00:00:00

abstract：OBJECTIVE:Pregnancy of unknown location (PUL) is not a diagnosis but a transient state used to classify a woman when she has a positive pregnancy test without definitive evidence of an intra-uterine or extra-uterine pregnancy on transvaginal ultrasonography. Management of a persisting PUL varies substantially, includin...

journal_title：Contemporary clinical trials

authors： Barnhart KT,Sammel MD,Stephenson M,Robins J,Hansen KR,Youssef WA,Santoro N,Eisenberg E,Zhang H,NICHD Cooperative Reproductive Medicine Network.

更新日期：2018-10-01 00:00:00

abstract：:In order to better characterize the safety profile of investigational new drugs (INDs) during clinical development, more interest and attention have been paid to ongoing safety monitoring and evaluation. The 2015 US FDA IND safety reporting draft guidance compels sponsors to periodically evaluate unblinded safety data...

journal_title：Contemporary clinical trials

authors： Lin LA,Zhan Y,Li H,Yuan SS,Ball G,Wang W

更新日期：2019-08-01 00:00:00

abstract：:Patients with Parkinson's disease and related disorders (PDRD) and their families have considerable unmet needs including non-motor symptom management, caregiver support, spiritual wellbeing, advance care planning, and end-of-life care. There is increasing interest in applying palliative care (PC) models to better mee...

journal_title：Contemporary clinical trials

authors： Kluger BM,Katz M,Galifianakis N,Pantilat SZ,Kutner JS,Sillau S,Gritz M,Jones J,Fairclough D,Sumrall M,Hall K,Miyasaki J

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND:Patients with progressive kidney disease experience increasing physiologic and psychosocial stressors and declining health-related quality of life (HRQOL). METHODS:We conducted a randomized, active-controlled, open-label trial to test whether a Mindfulness-based Stress Reduction (MBSR) program delivered in ...

journal_title：Contemporary clinical trials

authors： Gross CR,Reilly-Spong M,Park T,Zhao R,Gurvich OV,Ibrahim HN

更新日期：2017-06-01 00:00:00

abstract：:We developed a novel diagram to depict patient flow and outcomes in clinical trials. In contrast to flow diagrams such as the CONSORT chart, our diagram enables individual patient histories to be traced and depicts important patterns of treatment administration and outcomes, such as response and adverse events. Also, ...

journal_title：Contemporary clinical trials

authors： Schuller JC,Mayer M,Lanz D,Schmitz SF,Brauchli P,Leupin N

更新日期：2009-05-01 00:00:00

abstract：:Modified Zelen's approach is a randomization technique useful in multi-center trials where balance in treatment assignments within a center is desired. It has great balancing properties in a study with equal allocation to several treatment arms. This technique can also be used in studies with unequal allocation, where...

journal_title：Contemporary clinical trials

authors： Kuznetsova OM,Tymofyeyev Y

更新日期：2011-11-01 00:00:00

abstract：:Hepatitis C virus (HCV) is a leading cause of chronic liver disease. The natural history of HCV infection is heterogeneous, and a person infected with HCV can clear the virus or progress to a chronic infection. The chronic infection can remain asymptomatic for decades before the development of liver cirrhosis and/or c...

journal_title：Contemporary clinical trials

authors： Kang M,Nicolay U

更新日期：2008-09-01 00:00:00