Improving family caregiver and patient outcomes in lung cancer surgery: Study protocol for a randomized trial of the multimedia self-management (MSM) intervention.

abstract：BACKGROUND:Despite efforts by the U.S. Department of Defense to train behavioral health (BH) providers in evidence-based psychotherapies (EBPs) for posttraumatic stress disorder (PTSD), numerous barriers limit EBP implementation. A context-tailored implementation approach called TACTICS (Targeted Assessment and Context...

journal_title：Contemporary clinical trials

authors： Rosen CS,Davis CA,Riggs D,Cook J,Peterson AL,Young-McCaughan S,Comtois KA,Haddock CK,Borah EV,Dondanville KA,Finley EP,Jahnke SA,Poston WSC,Wiltsey-Stirman S,Neitzer A,Broussard CR,Brzuchalski MA,Clayton MSP,Conforte

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:This paper reports the protocol of a randomised, double-blind, placebo-controlled study to test the efficacy, safety, and tolerability of lubiprostone (LUB) vs. placebo on suppressing gut permeability in non-alcoholic fatty liver disease (NAFLD) patients with constipation. NAFLD, including non-alcoholic stea...

journal_title：Contemporary clinical trials

authors： Kessoku T,Imajo K,Kobayashi T,Honda Y,Kato T,Ogawa Y,Tomeno W,Kato S,Higurashi T,Yoneda M,Kirikoshi H,Kubota K,Taguri M,Yamanaka T,Usuda H,Wada K,Saito S,Nakajima A

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND:Functional dyspepsia (FD) is a common problem affecting up to 10-25% of individuals. FD accounts for significant health care costs and affects quality of life but has no definitive treatment. OBJECTIVES:The Functional Dyspepsia Treatment Trial (FDTT) aims to test whether treatment with an antidepressant (am...

journal_title：Contemporary clinical trials

authors： Talley NJ,Locke GR 3rd,Herrick LM,Silvernail VM,Prather CM,Lacy BE,DiBaise JK,Howden CW,Brenner DM,Bouras EP,El-Serag HB,Abraham BP,Moayyedi P,Zinsmeister AR

更新日期：2012-05-01 00:00:00

abstract：PURPOSE:To describe the strategies-based on the social triad concept of a partnership of researchers, school personnel and community-employed to recruit low-income, minority parent/caregivers of kindergarten children into a school-based tooth decay prevention trial in the United States. METHODS:The study site was an u...

journal_title：Contemporary clinical trials

authors： Nelson S,Milgrom P

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:The FEVER (Frail Elderly Vibration Exercise Response) study aims to address a paucity of research focusing on the use of Whole Body Vibration (WBV) by frail elderly who, with the highest levels of dependence and fall-related hospitalisation/mortality, potentially stand to benefit most from such accessible ex...

journal_title：Contemporary clinical trials

authors： Lark SD,Wadsworth DP

更新日期：2015-09-01 00:00:00

abstract：BACKGROUND:Children with sickle cell anemia (SCA) have an 11% risk of stroke by the age of 18. Chronic transfusion applied in patients detected to be at risk by transcranial Doppler allows a significant reduction of stroke risk. However, chronic transfusion exposes to several adverse events, including alloimmunization ...

journal_title：Contemporary clinical trials

authors： Chevret S,Verlhac S,Ducros-Miralles E,Dalle JH,de Latour RP,de Montalembert M,Benkerrou M,Pondarré C,Thuret I,Guitton C,Lesprit E,Etienne-Julan M,Elana G,Vannier JP,Lutz P,Neven B,Galambrun C,Paillard C,Runel C,Jube

更新日期：2017-11-01 00:00:00

abstract：BACKGROUND:Intake of sugar-sweetened beverages is associated with overweight in observational studies. A possible explanation is that liquid sugars do not satiate and that their intake is not compensated by reduced caloric intake from other foods. However, evidence from intervention studies for this hypothesis is incon...

journal_title：Contemporary clinical trials

authors： de Ruyter JC,Olthof MR,Kuijper LD,Katan MB

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Risk factors for cardiovascular disease (CVD) not only increase the risk for clinical CVD events, but also are associated with a cascade of neurophysiologic and neuroanatomic changes that increase the risk of cognitive impairment and dementia. Although epidemiological studies have shown that exercise and die...

journal_title：Contemporary clinical trials

authors： Blumenthal JA,Smith PJ,Welsh-Bohmer K,Babyak MA,Browndyke J,Lin PH,Doraiswamy PM,Burke J,Kraus W,Hinderliter A,Sherwood A

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:We evaluated the association of demographic and clinical characteristics with participation in an epidemiologic study of diabetes mellitus among youth. METHODS:SEARCH for Diabetes in Youth is a multicenter study of physician-diagnosed diabetes in youth under the age of 20 comprising a surveillance and a coh...

journal_title：Contemporary clinical trials

authors： Liese AD,Liu L,Davis C,Standiford D,Waitzfelder B,Dabelea D,Bell R,Williams D,Imperatore G,Lawrence JM

更新日期：2008-11-01 00:00:00

abstract：:Research indicates that exercise is an efficacious intervention for depression among adults; however, little is known regarding its efficacy for preventing postpartum depression. The Healthy Mom study was a randomized controlled trial examining the efficacy of an exercise intervention for the prevention of postpartum ...

journal_title：Contemporary clinical trials

authors： Lewis BA,Gjerdingen DK,Avery MD,Guo H,Sirard JR,Bonikowske AR,Marcus BH

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:The Covid-19 pandemic has caused fear and panic worldwide, forcing healthcare systems to disregard conventional practices and adopt innovation to contain the infection and death. Globally, there has been a rapid proliferation of research studies and clinical trials assessing risks, infectivity and treatment....

journal_title：Contemporary clinical trials

authors： Ibrahim H,Kamour AM,Harhara T,Gaba WH,Nair SC

更新日期：2020-09-01 00:00:00

abstract：PURPOSE:Black breast cancer survivors have high rates of obesity and low physical activity levels. Little is known about the acceptability and feasibility of interventions in this population. OBJECTIVE:A two-arm RCT was launched to assess the efficacy of a culturally targeted 12-week multimodal lifestyle intervention ...

journal_title：Contemporary clinical trials

authors： Sheppard VB,Hicks J,Makambi K,Hurtado-de-Mendoza A,Demark-Wahnefried W,Adams-Campbell L

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:The addition of specialty palliative care to standard oncology care improves outcomes for patients with advanced cancer and their caregivers, but many lack access to specialty care services. Primary palliative care-meaning basic palliative care services provided by clinicians who are not palliative care spec...

journal_title：Contemporary clinical trials

authors： Becker CL,Arnold RM,Park SY,Rosenzweig M,Smith TJ,White DB,Smith KJ,Schenker Y

更新日期：2017-03-01 00:00:00

abstract：INTRODUCTION:Focal ablation therapy is playing an increasing role in oncology and may reduce the toxicity of current surgical treatments while achieving adequate oncological benefit. Irreversible electroporation (IRE) has been proposed to be tissue-selective with potential advantages compared with current thermal-ablat...

journal_title：Contemporary clinical trials

authors： Wendler JJ,Porsch M,Nitschke S,Köllermann J,Siedentopf S,Pech M,Fischbach F,Ricke J,Schostak M,Liehr UB

更新日期：2015-07-01 00:00:00

abstract：BACKGROUND:The 9-valent human papillomavirus (HPV) (9vHPV) vaccine targets the four HPV types (6/11/16/18) covered by the licensed quadrivalent HPV (qHPV) vaccine and five additional types (31/33/45/52/58). A large outcome trial of 9vHPV vaccine was conducted. METHODS:An active control (qHPV vaccine) was used because ...

journal_title：Contemporary clinical trials

authors： Luxembourg A,Bautista O,Moeller E,Ritter M,Chen J

更新日期：2015-05-01 00:00:00

abstract：BACKGROUND:Patients with progressive kidney disease experience increasing physiologic and psychosocial stressors and declining health-related quality of life (HRQOL). METHODS:We conducted a randomized, active-controlled, open-label trial to test whether a Mindfulness-based Stress Reduction (MBSR) program delivered in ...

journal_title：Contemporary clinical trials

authors： Gross CR,Reilly-Spong M,Park T,Zhao R,Gurvich OV,Ibrahim HN

更新日期：2017-06-01 00:00:00

abstract：OBJECTIVE:Characteristics that may influence participation in DNA banks are not well defined. The purpose of this study was to examine characteristics associated with participation in a DNA bank among veterans diagnosed with Amyotrophic Lateral Sclerosis (ALS). METHODS:Veterans who screened eligible for the National R...

journal_title：Contemporary clinical trials

authors： DiMartino L,Allen KD,Kasarskis E,Lindquist JH,Coffman CJ,Oddone EZ,National Registry of Veterans with ALS.

更新日期：2007-09-01 00:00:00

abstract：:Chronic insomnia disorder is a prevalent condition and a significant proportion of these individuals also have obstructive sleep apnea (OSA). These two sleep disorders have distinct pathophysiology and are managed with different treatment approaches. High comorbidity rates have been a catalyst for emerging studies exa...

journal_title：Contemporary clinical trials

authors： Crawford MR,Turner AD,Wyatt JK,Fogg LF,Ong JC

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:Suboptimal diet and inactive lifestyle are among the most prevalent preventable causes of premature death. Interventions that target multiple behaviors are potentially efficient; however the optimal way to initiate and maintain multiple health behavior changes is unknown. OBJECTIVE:The Make Better Choices 2...

journal_title：Contemporary clinical trials

authors： Pellegrini CA,Steglitz J,Johnston W,Warnick J,Adams T,McFadden HG,Siddique J,Hedeker D,Spring B

更新日期：2015-03-01 00:00:00

abstract：:Missing data is common in clinical trials. Depending on the volume and nature of missing data, it may reduce statistical power for detecting treatment difference, introduce potential bias and invalidate conclusions. Non-responder imputation (NRI), where patients with missing information to determine endpoint status ar...

journal_title：Contemporary clinical trials

authors： Chen J,Hunter S,Kisfalvi K,Lirio RA

更新日期：2020-11-22 00:00:00

abstract：UNLABELLED:Latinos bear a disproportionate burden of the dual pandemic of obesity and diabetes. However, successful interventions addressing this disparity through primary care are lacking. To address this gap, the 5-year Vida Sana (Healthy Life) study tests a culturally adapted and technology-enhanced group-based Diab...

journal_title：Contemporary clinical trials

authors： Rosas LG,Lv N,Xiao L,Lewis MA,Zavella P,Kramer MK,Luna V,Ma J

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND:Bipolar Disorder (BD) is a common and severe form of mental illness. Pharmacotherapy is the main treatment offered, but has limited effectiveness, and there is increasing evidence that people with BD respond well to psychological interventions. Inequalities in access to face-to-face psychological interventio...

journal_title：Contemporary clinical trials

authors： Todd NJ,Solis-Trapala I,Jones SH,Lobban FA

更新日期：2012-07-01 00:00:00

abstract：INTRODUCTION:Breast cancer survivors face dual challenges: long term sequelae of treatment, and risk of recurrent disease. Obesity and a sedentary lifestyle complicate both challenges. The WISER Survivor trial assessed the effects of exercise and/or weight-loss on lymphedema, biomarkers of breast cancer recurrence, and...

journal_title：Contemporary clinical trials

authors： Winkels RM,Sturgeon KM,Kallan MJ,Dean LT,Zhang Z,Evangelisti M,Brown JC,Sarwer DB,Troxel AB,Denlinger C,Laudermilk M,Fornash A,DeMichele A,Chodosh LA,Schmitz KH

更新日期：2017-10-01 00:00:00

abstract：BACKGROUND:Women have higher rates of depression and often experience depression symptoms during critical reproductive periods, including adolescence, pregnancy, postpartum, and menopause. Collaborative care intervention models for mood disorders in patients receiving care in an OB-GYN clinic setting have not been eval...

journal_title：Contemporary clinical trials

authors： LaRocco-Cockburn A,Reed SD,Melville J,Croicu C,Russo JE,Inspektor M,Edmondson E,Katon W

更新日期：2013-11-01 00:00:00

abstract：OBJECTIVE:Pregnancy of unknown location (PUL) is not a diagnosis but a transient state used to classify a woman when she has a positive pregnancy test without definitive evidence of an intra-uterine or extra-uterine pregnancy on transvaginal ultrasonography. Management of a persisting PUL varies substantially, includin...

journal_title：Contemporary clinical trials

authors： Barnhart KT,Sammel MD,Stephenson M,Robins J,Hansen KR,Youssef WA,Santoro N,Eisenberg E,Zhang H,NICHD Cooperative Reproductive Medicine Network.

更新日期：2018-10-01 00:00:00

abstract：BACKGROUND:Basic research suggests that rapid increases in circulating inflammatory and hemostatic blood markers may trigger or indicate impending plaque rupture and coronary thrombosis, resulting in acute ischemic heart disease (IHD) events. However, these associations are not established in humans. METHODS AND RESUL...

journal_title：Contemporary clinical trials

authors： McDermott MM,Greenland P,Liu K,Tian L,Green D,Shah SJ,Huffman M,Wilkins J,Kibbe M,Liao Y,Huang CC,Skelly C,Jacobs C,McCarthy W,Auerbach A,Lloyd-Jones D

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND/AIMS:Cocaine use disorder (CUD) persists as a major public health problem in the United States. Response to evidence-based behavioral treatment has been shown to be predicted by dopaminergic dysfunction. Amphetamine formulations modulate dopaminergic systems and are one of the few agents with positive clinic...

journal_title：Contemporary clinical trials

authors： Blevins D,Carpenter KM,Martinez D,Mariani JJ,Levin FR

更新日期：2020-11-01 00:00:00

abstract：INTRODUCTION:Cardiac rehabilitation (CR) programs reduce overall and cardiovascular mortality in patients with a history of acute coronary events or revascularization procedures, but only 30% of patients enroll in CR and attrition rates reach up to 60%. Tai chi, a mind-body practice based on light/moderate aerobic exer...

journal_title：Contemporary clinical trials

authors： Salmoirago-Blotcher E,Wayne P,Bock BC,Dunsiger S,Wu WC,Stabile L,Yeh G

更新日期：2015-07-01 00:00:00

abstract：INTRODUCTION:In promoting the health of chronically ill children, the hospital should help children cope both medically and psychosocially with their disease. The University Children's Hospital of Nancy proposes adapted physical activity for hospitalized children, but the practice during hospitalization is not well dev...

journal_title：Contemporary clinical trials

authors： Speyer E,Vuillemin A,Herbinet A,Chastagner P,Briançon S

更新日期：2010-03-01 00:00:00

abstract：:This pilot study examined knowledge, understanding and perceived acceptability of key methodological concepts in clinical trials among injecting drug users (IDUs) in Sydney, Australia. Participants were clinical trial-experienced (n = 17) and trial-naïve (n = 99) IDUs recruited from community needle and syringe progra...

journal_title：Contemporary clinical trials

authors： Doab A,Topp L,Day CA,Dore GJ,Maher L

更新日期：2009-09-01 00:00:00