Value of glycolic acid analysis in ethylene glycol poisoning: A clinical case report and systematic review of the literature.


OBJECTIVE:To evaluate the clinical utility of glycolic acid (GA) determination in the diagnosis and prognosis of ethylene glycol (EG) intoxications. METHOD:Systematic review of serum and/or urine GA concentrations available in the literature in cases of EG poisoning. Present a clinical case in which the determination of the GA was decisive. RESULTS:In total, 137 patients were included. Serum GA concentrations (but not EG) of patients who survive are different from those who die. The optimal cut-off of serum GA to predict mortality was 990.5mg/L (sensitivity 85.2%, specificity 54.3%) with an Odds Ratio of 6.838 (2.868-16.302). In our clinical case, serum EG was negative; however, urine GA was positive (1230.7mg/L). CONCLUSIONS:In all suspected cases of EG poisoning, it is advisable to carry out the simultaneous analysis of EG and GA.


Forensic Sci Int


Tuero G,González J,Sahuquillo L,Freixa A,Gomila I,Elorza MÁ,Barceló B




Has Abstract


2018-09-01 00:00:00












  • The experience of the Forensic Anthropology Service of the Medical Examiner's Office in Porto Alegre, Brazil.

    abstract::The Forensic Anthropology Service of the Medical Examiner's Office of Porto Alegre was created in September 1997 to examine human skeletons, establish identification and identify lesions that may explain death. From September 1997 to December 2006, 344 skeletons were examined (mean: 37 examinations/year), and 322 were...

    journal_title:Forensic science international

    pub_type: 杂志文章


    authors: Vaz M,Benfica FS

    更新日期:2008-08-06 00:00:00

  • The cribriform approach to the retrieval of palynological evidence from the turbinates of murder victims.

    abstract::As well as being the route for gaseous exchange, the nasal passages protect the lungs from debris and fine particulates inhaled during breathing. Foreign particles are trapped by mucus produced by membranes that line the upper respiratory tract. Even when a corpse has skeletonised, particles can be retrieved from the ...

    journal_title:Forensic science international

    pub_type: 杂志文章


    authors: Wiltshire PE,Black S

    更新日期:2006-11-22 00:00:00

  • An investigation into the suitability of some etching reagents to restoring obliterated stamped numbers on cast iron engine blocks of cars.

    abstract::Most of the automotive companies use cast iron for their engine blocks. Restoration of obliterated number on these iron surfaces by chemical etching is known to be quite difficult. Heating of the obliterated surface using oxyacetylene flame is an alternative recovery treatment suggested in literature and used in pract...

    journal_title:Forensic science international

    pub_type: 杂志文章


    authors: Abdul Wahab MF,Mohamad Ghani NI,Kuppuswamy R

    更新日期:2012-11-30 00:00:00

  • Experimental study of the coupling parameters influencing the terminal effects of thoracic blunt ballistic impacts.

    abstract::The objective of the study is to better understand how blunt projectile ballistic parameters and material properties influence the events leading to injuries. The present work focuses on lateral thoracic impacts and follows an experimental approach. The projectiles are made with a soft foam nose assembled with a rigid...

    journal_title:Forensic science international

    pub_type: 杂志文章


    authors: Pavier J,Langlet A,Eches N,Prat N,Bailly P,Jacquet JF

    更新日期:2015-07-01 00:00:00

  • Aged fingerprints for DNA profile: First report of successful typing.

    abstract::Fingerprint detection and Short Tandem Repeat (STR) typing are two approaches used for identification of individuals. The main goal of forensic laboratories is the development of a standardized protocol to obtain an STR profile from latent fingerprints, by typing the DNA transferred onto touched objects. The results o...

    journal_title:Forensic science international

    pub_type: 杂志文章


    authors: Romano CG,Mangiaracina R,Donato L,D'Angelo R,Scimone C,Sidoti A

    更新日期:2019-09-01 00:00:00

  • Identification of fatty acid methyl esters (FAMEs) in postmortem tissue. A new marker of alcohol abuse?

    abstract::Based on a method that combines thin layer chromatography and gas chromatography, it proved possible to detect postmortem fatty acid methyl esters (FAMEs) in human tissues (pancreas, liver, heart and adipose tissue). The highest concentrations were found in the pancreas, medium concentrations in the liver and adipose ...

    journal_title:Forensic science international

    pub_type: 杂志文章


    authors: Emrich J,Sprung R,Sammler J,Remberg G

    更新日期:1997-02-07 00:00:00

  • Forensic osteological investigations in Kosovo.

    abstract::A team of Finnish forensic experts performed investigations of alleged mass graves in Kosovo under the mandate of the European Union (EU). Human skeletal remains from two locations were examined. The remains contained three almost complete skeletons, and individual bones and bone fragments, part of which were burned. ...

    journal_title:Forensic science international

    pub_type: 杂志文章


    authors: Rainio J,Hedman M,Karkola K,Lalu K,Peltola P,Ranta H,Sajantila A,Söderholm N,Penttilä A

    更新日期:2001-10-01 00:00:00

  • The psychodynamics of the presidential assassin and an examination of the theme/graphic variables of his threatening correspondence.

    abstract::Many document examiners recognize the importance of an individuals 'state of mind' and its effect on handwriting but historically have steered clear of working closely with psychiatrists, linguists, or psychologists in understanding the interaction of nervous impulses and motor responses on the final handwritten produ...

    journal_title:Forensic science international

    pub_type: 杂志文章


    authors: Cain S

    更新日期:1982-01-01 00:00:00

  • Age at death determinations for autopsied remains based on aspartic acid racemization in tooth dentin: importance of postmortem conditions.

    abstract::The extent of aspartic acid racemization in human dentin can be used to assess chronological age of the individual. This novel chemical method of aging human remains has potential applications in forensic sciences. Six autopsy cases have been analyzed for D/L aspartic acid contents, and their ages at death calculated....

    journal_title:Forensic science international

    pub_type: 杂志文章


    authors: Masters PM

    更新日期:1986-11-01 00:00:00

  • Detection of anionic energetic material residues in enhanced fingermarks on porous and non-porous surfaces using ion chromatography.

    abstract::The ability to link criminal activity and identity using validated analytical approaches can be of great value to forensic scientists. Herein, the factors affecting the recovery and detection of inorganic and organic energetic material residues within chemically or physically enhanced fingermarks on paper and glass su...

    journal_title:Forensic science international

    pub_type: 杂志文章


    authors: Love C,Gilchrist E,Smith N,Barron L

    更新日期:2013-09-10 00:00:00

  • A genetic study of the short tandem repeat systems VWA and TH01 in an Austrian population.

    abstract::Allele- and genotype frequencies of the two short tandem repeat (STR) systems VWA and TH01 were determined in an Austrian population sample by polymerase chain reaction (PCR) analysis. A total of 9 alleles for VWA and 6 alleles for TH01 could be observed in a population of 278 (VWA) and 276 (TH01) individuals. Both sy...

    journal_title:Forensic science international

    pub_type: 杂志文章


    authors: Neuhuber F,Radacher M

    更新日期:1997-06-23 00:00:00

  • Instant detection and identification of concealed explosive-related compounds: Induced Stokes Raman versus infrared.

    abstract::The instant detection of explosives and explosive-related compounds has become an urgent priority in recent years for homeland security and counter-terrorism applications. Modern techniques should offer enhancement in selectivity, sensitivity, and standoff distances. Miniaturisation, portability, and field-ruggedisati...

    journal_title:Forensic science international

    pub_type: 杂志文章


    authors: Elbasuney S,El-Sherif AF

    更新日期:2017-01-01 00:00:00

  • Malpractice--role of the forensic pathologist in Germany.

    abstract::Medicolegal malpractice assessments have been an important part of the work of forensic pathologists. Not only botchers are concerned but also physicians of all clinical subjects, especially malpractice charges claiming a malpractice leading to death. Single long articles and book chapters have been published about ma...

    journal_title:Forensic science international

    pub_type: 历史文章,杂志文章


    authors: Dettmeyer R,Preuss J,Madea B

    更新日期:2004-09-10 00:00:00

  • Linear rate of change in the product of erythrocyte water content and potassium concentration during the 0-120-hour postmortem period in the rat.

    abstract::An accurate and reproducible technique was employed for measurement of water content (RBCH2O) and potassium concentration (RBCK) in rat erythrocytes post mortem. Coefficients of variation for determination of RBCH2O and RBCK, as estimated from the results of duplicate analyses (n = 36), were 1.21% and 1.17%, respectiv...

    journal_title:Forensic science international

    pub_type: 杂志文章


    authors: Querido D,Pillay B

    更新日期:1988-07-01 00:00:00

  • Analysis of 418 cases of sexual assault.

    abstract::The aim of the study was to describe victim, assailant, assault characteristics for sexual assault victims according to the time between the last sexual assault and the examination, and to provide descriptive data on medico-legal findings. The study was based on 418 examined victims of sexual assault during the year 1...

    journal_title:Forensic science international

    pub_type: 杂志文章


    authors: Grossin C,Sibille I,Lorin de la Grandmaison G,Banasr A,Brion F,Durigon M

    更新日期:2003-01-28 00:00:00

  • Genetic diversity and forensic evaluation of 10 STR loci in Lodz region of Poland.

    abstract::Allele frequency data and forensic efficiency parameters for 10 STR loci: D3S1358, vWA, D16S539, D2S1338, D8S1179, D21S11, D18S51, D19S433, TH01 and FGA, were estimated from a sample of 207 unrelated individuals in Lodz region of Poland. ...

    journal_title:Forensic science international

    pub_type: 杂志文章


    authors: Jacewicz R,Berent J,Prośniak A,Kadłubek M,Szram S

    更新日期:2003-10-14 00:00:00

  • Analysis of the D1S80 (pMCT118) VNTR locus polymorphism in a native Kuwaiti population by the polymerase chain reaction.

    abstract::We have determined the allele and genotype frequencies at the hypervariable locus D1S80 in a native Kuwaiti population using the polymerase chain reaction technique and subsequent high resolution gel electrophoresis. In a sample of 200 individuals, 21 alleles and 57 genotypes were detected. The alleles with 18 and 24 ...

    journal_title:Forensic science international

    pub_type: 杂志文章


    authors: al-Nassar KE,Mathew J,Thomas N,Fatania HR

    更新日期:1996-04-02 00:00:00

  • Determination of the R- and S-enantiomers of methylone and ethylone in seized drugs by enantioselective liquid chromatography tandem mass spectrometry analysis.

    abstract::Synthetic cathinones constitute a major class of the new psychoactive substances (NPS) that have come to dominate recreational drug abuse in recent years. As synthetic cathinones are all chiral molecules, the use of chiral analysis to determine their enantiomeric ratios (ER) in seized drug samples can assist in the id...

    journal_title:Forensic science international

    pub_type: 杂志文章


    authors: Lin HR,Kuo FW

    更新日期:2020-12-01 00:00:00

  • The use of serial measurement of plasma cholinesterase in the management of acute poisoning with organophosphates and carbamates.

    abstract:OBJECTIVE:To evaluate the benefits of using serial measurements of plasma cholinesterase (butyrylcholinesterase, BuChE) activity in the management of cholinesterase inhibitor insecticidal poisoning. METHOD:After establishing and validating BuChE activity test, and making it available for clinical service in the toxico...

    journal_title:Forensic science international

    pub_type: 杂志文章


    authors: Abdullat IM,Battah AH,Hadidi KA

    更新日期:2006-10-16 00:00:00

  • A systematic approach to the interpretation of gunshot wound trauma to the cranium.

    abstract::This chapter employs the fracture assessment triad, a systematic analytical approach, as a vehicle to explore the components used to interpret gunshot trauma to the cranium. First, a list of pertinent observations associated with gunshot trauma to the cranium is presented with a brief description of each. These featur...

    journal_title:Forensic science international

    pub_type: 杂志文章


    authors: Berryman HE

    更新日期:2019-08-01 00:00:00

  • Estimation of sex from sternal measurements in a Western Australian population.

    abstract::In Australia, particularly Western Australia, there is a relative paucity of contemporary population-specific morphometric standards for the estimation of sex from unknown skeletal remains. This is largely a historical artefact from lacking, or poorly documented, repositories of human skeletons available for study. Ho...

    journal_title:Forensic science international

    pub_type: 杂志文章


    authors: Franklin D,Flavel A,Kuliukas A,Cardini A,Marks MK,Oxnard C,O'Higgins P

    更新日期:2012-04-10 00:00:00

  • Errors in the determination of the point of origin of bloodstains.

    abstract::Bloodstain pattern analysts are sometimes called upon to determine the point of origin of a pattern of bloodstains. A derivation of expressions for the uncertainties deltaX and deltaY in the coordinates of the point of origin P(X, Y) of two bloodstains on a surface has recently been published. These uncertainties were...

    journal_title:Forensic science international

    pub_type: 杂志文章


    authors: Rowe WF

    更新日期:2006-08-10 00:00:00

  • The changing phenomenology of drug death over the years.

    abstract::When inspecting the scene the circumstances under which a body is found and the findings on the body surface may give first clues to premortal drug abuse. Besides fresh and/or old injection marks tattoos, underweight and signs of physical neglect, especially after long-term abuse, are mentioned in literature. The inci...

    journal_title:Forensic science international

    pub_type: 杂志文章


    authors: Bohnert M,Hafezi M,Pollak S

    更新日期:2001-12-27 00:00:00

  • Serial postmortem thoracic radiographic findings in canine cadavers.

    abstract::Postmortem radiographic examinations of animals are often performed in judicial investigation to rule out gunshot and fractures due to cruelty. Literature describing postmortem changes seen on radiographs of animals is rarely available. Serial thoracic radiography of six recently euthanized dogs was performed in an in...

    journal_title:Forensic science international

    pub_type: 杂志文章


    authors: Heng HG,Selvarajah GT,Lim HT,Ong JS,Lim J,Ooi JT

    更新日期:2009-07-01 00:00:00

  • A comparative study of ethchlorvynol levels in blood versus bone marrow.

    abstract::Bone marrow may be utilized as an alternative biological sample in cases where uncontaminated blood samples are not available for analyses. Bone marrow/blood ratios of ethchlorvynol as a function of time and dosage level were determined in 40 rabbits. A modified quantitative analysis that produced accurate and reprodu...

    journal_title:Forensic science international

    pub_type: 杂志文章


    authors: Winek CL,Cibulas W Jr,Wahba WW

    更新日期:1981-05-01 00:00:00

  • Injuries due to deliberate violence in areas of Argentina. I. The extent of violence. Copenhagen Study Group.

    abstract::As part of a transcultural investigation of violent behaviour in Argentina and Denmark an analysis was made of the incidents involving deliberate violence as registered in the emergency wards of Hospital Fernandez and Hospital Pinero in Capital Federal Buenos Aires over a period of 13 and 17 months, respectively. In t...

    journal_title:Forensic science international

    pub_type: 杂志文章


    authors: Aalund O,Danielsen L,Katz E,Mazza PH

    更新日期:1989-07-01 00:00:00

  • Illegal drugs and delinquency.

    abstract::An interrelation between consumption of illegal drugs and committing an indictable offence has been repeatedly discussed in literature. In a retrospective study serum concentrations of illegal and legal drugs as well as data originating from police reports and examinations by physicians taking blood from individuals b...

    journal_title:Forensic science international

    pub_type: 杂志文章


    authors: Kirschbaum KM,Grigoleit L,Hess C,Madea B,Musshoff F

    更新日期:2013-03-10 00:00:00

  • Application of simple Bayesian statistics to a sample database for source correspondence.

    abstract::Bayesian statistics was applied to a small sample database of the tensile properties of five different brands of writing paper which were perceptibly similar. The measured parameters in the database were found to overlap for the five brands. This posed a limitation to the application of the classical approach for "mat...

    journal_title:Forensic science international

    pub_type: 杂志文章


    authors: Kumar R

    更新日期:2010-02-25 00:00:00

  • Changes in thallium distribution in the scalp hair after an intoxication incident.

    abstract::In cases of criminal thallium poisoning, forensic investigation is required to identify the amount and time of thallium exposure. Usually, blood and urine thallium levels are respectively used as biomarkers. Additionally, hair has the unique potential to reveal retrospective information. Although several studies have ...

    journal_title:Forensic science international

    pub_type: 杂志文章


    authors: Matsukawa T,Chiba M,Shinohara A,Matsumoto-Omori Y,Yokoyama K

    更新日期:2018-10-01 00:00:00

  • Driving under the influence of drugs -- evaluation of analytical data of drugs in oral fluid, serum and urine, and correlation with impairment symptoms.

    abstract::A study was performed to acquire urine, serum and oral fluid samples in cases of suspected driving under the influence of drugs of abuse. Oral fluid was collected using a novel sampling/testing device (Dräger DrugTest System). The aim of the study was to evaluate oral fluid and urine as a predictor of blood samples po...

    journal_title:Forensic science international

    pub_type: 杂志文章


    authors: Toennes SW,Kauert GF,Steinmeyer S,Moeller MR

    更新日期:2005-09-10 00:00:00