Abstract:
:We report the first atomic resolution structure of an animal virus, human rhinovirus 14. It is strikingly similar to known icosahedral plant RNA viruses. Four neutralizing immunogenic regions have been identified. These, and corresponding antigenic sequences of polio and foot-and-mouth disease viruses, reside on external protrusions. A large cleft on each icosahedral face is probably the host cell receptor binding site.
journal_name
Naturejournal_title
Natureauthors
Rossmann MG,Arnold E,Erickson JW,Frankenberger EA,Griffith JP,Hecht HJ,Johnson JE,Kamer G,Luo M,Mosser AGdoi
10.1038/317145a0subject
Has Abstract,Author List Incompletepub_date
1985-09-12 00:00:00pages
145-53issue
6033eissn
0028-0836issn
1476-4687journal_volume
317pub_type
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