The 2016 WHO versus 2008 WHO Criteria for the Diagnosis of Chronic Myelomonocytic Leukemia.

abstract：:Candidemia due to uncommon Candida spp. appears to be increasing in incidence. C. dubliniensis has been increasingly recovered from individuals not infected with HIV. Identification of C. dubliniensis can be problematic in routine clinical practice due to its phenotypic resemblance to C. albicans. We report the first ...

journal_title：Annals of laboratory medicine

authors： Yu N,Kim HR,Lee MK

更新日期：2012-05-01 00:00:00

abstract：:Procalcitonin (PCT) is used as a biomarker for the diagnosis of sepsis, severe sepsis and septic shock. At the same time, PCT has also been used to guide antibiotic therapy. This review outlines the main indications for PCT measurement and points out possible pitfalls. The classic indications for PCT measurement are: ...

journal_title：Annals of laboratory medicine

authors： Meisner M

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND:Many laboratories use 4 delta check methods: delta difference, delta percent change, rate difference, and rate percent change. However, guidelines regarding decision criteria for selecting delta check methods have not yet been provided. We present new decision criteria for selecting delta check methods for e...

journal_title：Annals of laboratory medicine

authors： Park SH,Kim SY,Lee W,Chun S,Min WK

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:Mutations in calreticulin (CALR) have been reported to be key markers in the molecular diagnosis of myeloid proliferative neoplasms. In most previous reports, CALR mutations were analyzed by using Sanger sequencing. Here, we report a new, rapid, and convenient system for screening CALR mutations without sequ...

journal_title：Annals of laboratory medicine

authors： Jeong JH,Lee HT,Seo JY,Seo YH,Kim KH,Kim MJ,Lee JH,Park J,Hong JS,Park PW,Ahn JY

更新日期：2016-07-01 00:00:00

abstract：:We compared the activities of tedizolid to those of linezolid and other commonly used antimicrobial agents against gram-positive cocci recovered from patients with skin and skin structure infections (SSSIs) and hospital-acquired pneumonia (HAP) in Korean hospitals. Gram-positive isolates were collected from 356 patien...

journal_title：Annals of laboratory medicine

authors： Lee Y,Hong SK,Choi S,Im W,Yong D,Lee K

更新日期：2015-09-01 00:00:00

abstract：BACKGROUND:This study was aimed to investigate the genetic diversity and antibiotic resistance profile of the nosocomial infection agent Acinetobacter baumannii from a medical intensive care unit (ICU) in a teaching hospital in Suzhou, China. METHODS:The genetic relationship among A. baumannii isolates in an ICU was i...

journal_title：Annals of laboratory medicine

authors： Zhong Q,Xu W,Wu Y,Xu H

更新日期：2012-11-01 00:00:00

abstract：:ABO discrepancy refers to an inconsistency between red cell and serum typings and has various causes, including hypogammaglobulinemia. IgM deficiency is a rare disorder that may accompany several conditions such as infection and autoimmune disorders. Here, we describe a case of IgM deficiency discovered during the eva...

journal_title：Annals of laboratory medicine

authors： Jung CL,Cha MK,Jun BH,Hong KS

更新日期：2013-05-01 00:00:00

abstract：BACKGROUND:Although single antigen bead assays (SAB) are approved qualitative tests, the median fluorescence intensity (MFI) values obtained from SAB are frequently used in combination with quantitative significances for diagnostic purposes. To gauge the reproducibility of SAB results, we assessed the interlaboratory v...

journal_title：Annals of laboratory medicine

authors： Oh EJ,Park H,Park KU,Kang ES,Kim HS,Song EY

更新日期：2015-05-01 00:00:00

abstract：BACKGROUND:Methicillin-resistant Staphylococcus aureus (MRSA) bacteremia with a vancomycin minimum inhibitory concentration (MIC) of 2 µg/mL presents a high rate of therapeutic failure in response to vancomycin. In addition, polymorphism in accessory gene regulator (agr) is associated with vancomycin therapeutic effect...

journal_title：Annals of laboratory medicine

authors： Park MJ,Kim HS,Kim HS,Kim JS,Song W,Kim MY,Lee YK,Kang HJ

更新日期：2015-07-01 00:00:00

abstract：BACKGROUND:The aim of this study was to evaluate a newly developed PCR-based reverse blot hybridization assay (PCR-REBA), REBA Sepsis-ID (M&D, Wonju, Korea), to rapidly detect the presence of bacteremia and antimicrobial resistance gene in blood culture samples. METHODS:One thousand four hundred consecutive blood cult...

journal_title：Annals of laboratory medicine

authors： Park SD,Lee G,Wang HY,Park M,Kim S,Kim H,Kim J,Kim YK,Kim HY,Lee H,Uh Y,Kim JB

更新日期：2014-11-01 00:00:00

abstract：BACKGROUND:A newborn screening (NBS) program has been utilized to detect asymptomatic newborns with inherited metabolic diseases (IMDs). There have been some bottlenecks such as false-positives and imprecision in the current NBS tests. To overcome these issues, we developed a multigene panel for IMD testing and investi...

journal_title：Annals of laboratory medicine

authors： Park KJ,Park S,Lee E,Park JH,Park JH,Park HD,Lee SY,Kim JW

更新日期：2016-11-01 00:00:00

abstract：BACKGROUND:Differentiation of atypical pathogens is important for community-acquired pneumonia (CAP). In this study, we compared sputum and nasopharyngeal swabs (NPS) for use in detection of Mycoplasma pneumoniae (MP), Chlamydophila pneumoniae (CP), and Legionella pneumophila (LP), using Seeplex PneumoBacter ACE Detect...

journal_title：Annals of laboratory medicine

authors： Cho MC,Kim H,An D,Lee M,Noh SA,Kim MN,Chong YP,Woo JH

更新日期：2012-03-01 00:00:00

abstract：:We aimed to observe antimicrobial resistance patterns and integron carriage of Escherichia coli isolates causing community-acquired infections. Two hundred sixty-eight E. coli strains were obtained from outpatients with various infections at different polyclinics at the 82nd Year of State Hospital in Rize, Turkey. Sus...

journal_title：Annals of laboratory medicine

authors： Copur-Cicek A,Ozgumus OB,Saral A,Sandalli C

更新日期：2014-03-01 00:00:00

abstract：:Guidelines recommend that clinical laboratories perform phenotypic tests (nitrocefin-based test and penicillin 10-U [P10] or 1-U [P1] zone edge tests) to detect penicillinase in Staphylococcus aureus isolates. This study aimed to assess the prevalence of blaZ encoding penicillinase and perform various phenotypic tests...

journal_title：Annals of laboratory medicine

authors： Takayama Y,Tanaka T,Oikawa K,Fukano N,Goto M,Takahashi T

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:D-dimer is used widely as a diagnostic aid in low- and moderate-risk patients with suspected venous thromboembolism (VTE). While our laboratory utilizes VIDAS D-dimer analyzer (bioMérieux SA, France), our emergency department (ED) recently procured a D-dimer analyzer AQT90 FLEX (Radiometer Medical ApS, Denma...

journal_title：Annals of laboratory medicine

authors： Perveen S,Unwin D,Shetty AL

更新日期：2013-01-01 00:00:00

abstract：:Metachromatic leukodystrophy (MLD) is an autosomal recessive disease caused by a deficiency in arylsulfatase A (ARSA). However, decreased ARSA activity is also observed in pseudodeficiency (PD). To distinguish between MLD and PD, we performed gene mutation and sulfatide analyses by using dried blood spots (DBSs) from ...

journal_title：Annals of laboratory medicine

authors： Han M,Jun SH,Lee YJ,Eun BL,Lee SJ,Seong MW,Park SS,Song SH,Park HD,Song J

更新日期：2015-07-01 00:00:00

abstract：:As various linezolid resistance mechanisms have been identified in methicillin-resistant Staphylococcus aureus (MRSA), we investigated the molecular characteristics of MRSA with elevated linezolid minimum inhibitory concentrations (MICs), using the VITEK 2 system (bioMérieux, Marcy-l'Étoile, France). Twenty-seven MRSA...

journal_title：Annals of laboratory medicine

authors： Yoo IY,Kang OK,Shim HJ,Huh HJ,Lee NY

更新日期：2020-01-01 00:00:00

abstract：:Myocardial infarction (MI) is the leading cause of death in the developed world. Biomarkers have an essential role in diagnosis, risk stratification, guiding management and clinical decision making in the setting of patients presenting with signs and symptoms of MI. Cardiac troponin (cTn) rose to prominence during the...

journal_title：Annals of laboratory medicine

authors： Christenson E,Christenson RH

更新日期：2013-09-01 00:00:00

abstract：Background:HLA-DQ typing in deceased donors is not mandatory in Korea. Therefore, when patients develop DQ antibodies after kidney transplantation (KT) from deceased donor, it is impossible to determine whether they are donor-specific antibodies (DSA). We developed DQ prediction programs for the HLA gene and evaluated ...

journal_title：Annals of laboratory medicine

authors： Kim SK,Yang JJ,Hwang SH,Sung H,Shin S,Ko SY,Oh HB

更新日期：2021-03-01 00:00:00

abstract：BACKGROUND:False-positive fecal immunochemical test (FIT) results in the National Cancer Screening Program (NCSP) for colorectal cancer may lead to unnecessary procedures, such as colonoscopies, increasing the medical costs. We estimated reductions in the cost of National Health Insurance according to the accreditation...

journal_title：Annals of laboratory medicine

authors： Jun JK,Sung NY,Song SH,Hong S,Jang MA,Song J,Kim JH,Min WK,Lee YK

更新日期：2018-05-01 00:00:00

abstract：BACKGROUND:During the 2015 outbreak of Middle East Respiratory Syndrome coronavirus (MERS-CoV), six different commercial MERS-CoV RNA detection kits based on real-time reverse-transcription polymerase chain reaction (rRT-PCR) were available in Korea. We performed analytical and clinical validations of these kits. METH...

journal_title：Annals of laboratory medicine

authors： Kim MN,Ko YJ,Seong MW,Kim JS,Shin BM,Sung H

更新日期：2016-09-01 00:00:00

abstract：BACKGROUND:Clarithromycin, amoxicillin, metronidazole, tetracycline, and levofloxacin have been commonly used for the eradication of Helicobacter pylori. We compared the change in antibiotic resistance of H. pylori strains during two separate periods and investigated the effect of antibiotic resistance on H. pylori era...

journal_title：Annals of laboratory medicine

authors： An B,Moon BS,Kim H,Lim HC,Lee YC,Lee G,Kim SH,Park M,Kim JB

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:Delamanid, bedaquiline, and linezolid have recently been approved for the treatment of multidrug- and extensively drug-resistant (MDR and XDR, respectively) tuberculosis (TB). To use these drugs effectively, drug susceptibility tests, including rapid molecular techniques, are required for accurate diagnosis ...

journal_title：Annals of laboratory medicine

authors： Yang JS,Kim KJ,Choi H,Lee SH

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:Although Th2 immune activation is predominant in allergic diseases, neopterinlevels and indoleamine 2,3-dioxygenase (IDO)-1 activity (kynurenine:tryptophan ratio), which reflect Th1 immune activity, increase with interferon-gamma (IFN-γ) stimulation. We investigated neopterin, tryptophan, and kynurenine leve...

journal_title：Annals of laboratory medicine

authors： Ünüvar S,Erge D,Kılıçarslan B,Gözükara Bağ HG,Çatal F,Girgin G,Baydar T

更新日期：2019-05-01 00:00:00

abstract：BACKGROUND:Narcolepsy is a neurologic disorder characterized by excessive daytime sleepiness, symptoms of abnormal rapid eye movement (REM) sleep, and a strong association with HLA-DRB1*1501, -DQA1*0102, and -DQB1*0602. Here, we investigated the clinico-physical characteristics of Korean patients with narcolepsy, their...

journal_title：Annals of laboratory medicine

authors： Woo HI,Joo EY,Hong SB,Lee KW,Kang ES

更新日期：2012-01-01 00:00:00

abstract：:[This corrects the article on p. 439 in vol. 40.]. ...

journal_title：Annals of laboratory medicine

authors： Sung H,Roh KH,Hong KH,Seong MW,Ryoo N,Kim HS,Lee J,Kim SY,Ryu SW,Kim MN,Han MG,Lee SW,Lee H,Yoo CK

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND:Hepatitis E virus (HEV) causes epidemics in developing countries and is primarily transmitted through the fecal-oral route. There have been recent reports on the zoonotic spread of the virus, and several animal species, primarily pigs, have been recognized as reservoirs of HEV. Because of its possible spread...

journal_title：Annals of laboratory medicine

authors： Mazalovska M,Varadinov N,Koynarski T,Minkov I,Teoharov P,Lomonossoff GP,Zahmanova G

更新日期：2017-07-01 00:00:00

abstract：Background:Plasma cell myeloma (PCM) is caused by immune dysregulation. We evaluated the expression of immune checkpoint programmed cell death protein-1 (PD-1) on T cell subsets in PCM patients according to disease course and cytogenetic abnormalities. This study aimed to find a target group suitable for therapeutic us...

journal_title：Annals of laboratory medicine

authors： Lee MY,Park CJ,Cho YU,You E,Jang S,Seo EJ,Lee JH,Yoon DH,Suh C

更新日期：2021-05-01 00:00:00

abstract：BACKGROUND:In the past, ABO incompatibility was an absolute contraindication for solid organ transplantation. However, multiple recent trials have suggested strategies for overcoming the reactions between graft antigens and recipient antibodies that cause graft rejection. In this study, we determined the usefulness of ...

journal_title：Annals of laboratory medicine

authors： Yoo S,Lee EY,Huh KH,Kim MS,Kim YS,Kim HO

更新日期：2012-07-01 00:00:00

abstract：:In 2015, the American College of Medical Genetics and Genomics (ACMG), together with the Association for Molecular Pathology (AMP), published the latest guidelines for the interpretation of sequence variants, which have been widely adopted into clinical practice. Despite these standardized efforts, the degrees of subj...

journal_title：Annals of laboratory medicine

authors： Kim YE,Ki CS,Jang MA

更新日期：2019-09-01 00:00:00