The Role of RNA in Biological Phase Separations.

Abstract:

:Phase transitions that alter the physical state of ribonucleoprotein particles contribute to the spacial and temporal organization of the densely packed intracellular environment. This allows cells to organize biologically coupled processes as well as respond to environmental stimuli. RNA plays a key role in phase separation events that modulate various aspects of RNA metabolism. Here, we review the role that RNA plays in ribonucleoprotein phase separations.

journal_name

J Mol Biol

authors

Fay MM,Anderson PJ

doi

10.1016/j.jmb.2018.05.003

subject

Has Abstract

pub_date

2018-11-02 00:00:00

pages

4685-4701

issue

23

eissn

0022-2836

issn

1089-8638

pii

S0022-2836(18)30391-7

journal_volume

430

pub_type

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