Abstract：
INTRODUCTION:Glucocorticoid activity is disrupted in substance users including khat chewers who also use tobacco. Anger, dysphoria, and anxiety can mediate this relationship. The aim of this study was to contrast emotion dysregulation and substance use variables as predictors of post-stress cortisol output. MATERIALS AND METHODS:Comparable numbers of males (n = 90) and females (n = 85) including controls, khat only, and concurrent khat and tobacco users participated in a stress study. Depressive affect, anxiety, anger, substance use patterns, and saliva samples were collected following a standardized laboratory stress manipulation. RESULTS:Regression analysis showed that high depression and low anxiety was associated with high post-stress cortisol, but only in co-users of tobacco and khat. Males, but not females, showed a significant association between co-use of khat and tobacco and cortisol, which appears to be mediated by frequency of use. The link between anxiety and post-stress cortisol in the co-users remained significant after controlling for nicotine dependence and substance use frequency. CONCLUSION:Anxiety predicted the neuroendocrine consequences of concurrent use of tobacco and khat above and beyond sex, nicotine dependence, anger, and substance use frequency. Sex differences, however, are related to differences in nicotine dependence.
journal_name
Addict Behavjournal_title
Addictive behaviorsauthors
Lemieux AM,Nakajima M,Saif-Ali R,Al-Habori M,Dokam A,al'Absi Mdoi
10.1016/j.addbeh.2018.02.033subject
Has Abstractpub_date
2018-07-01 00:00:00pages
195-201eissn
0306-4603issn
1873-6327pii
S0306-4603(18)30104-7journal_volume
82pub_type
杂志文章abstract：:The negative impact of maternal cigarette smoking during pregnancy on the growth and development of the foetus has been well documented. However, the long-term effects of the subsequent cognitive and physical development of the child are less clearly understood. This article presents a critical review of the literatur...
journal_title：Addictive behaviors
pub_type： 杂志文章
doi：10.1016/s0306-4603(98)00022-7
更新日期：1998-09-01 00:00:00
abstract：:People in modern society use an ever increasing variety of psychoactive substances to help them cope with the increasing amount of stress they experience in the course of their lives. A survey was undertaken to investigate the role of smoking as a coping strategy and the relationship between smoking, the other coping ...
journal_title：Addictive behaviors
pub_type： 杂志文章
doi：10.1016/0306-4603(85)90002-4
更新日期：1985-01-01 00:00:00
abstract：BACKGROUND:This is the first study to examine predictors of successful cessation in African American (AA) light smokers treated within a placebo-controlled trial of bupropion. METHODS:We analyzed data from a randomized, double-blind, placebo-controlled trial of bupropion and health education for 540 African American l...
journal_title：Addictive behaviors
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.addbeh.2012.11.010
更新日期：2013-03-01 00:00:00
abstract：BACKGROUND:Cocaine addiction and pathological gambling are commonly associated with steeper (impulsive) discounting of delayed rewards, which promotes ongoing drug and gambling behaviors. However, it is yet unclear whether impulsive delay discounting is a stable trait in cocaine and gambling disorders during abstinence...
journal_title：Addictive behaviors
pub_type： 杂志文章
doi：10.1016/j.addbeh.2014.06.001
更新日期：2014-11-01 00:00:00
abstract：INTRODUCTION:The CRAFFT questionnaire is a widely utilized measure of problematic alcohol and drug use. The brief screening instrument has been translated into multiple languages, and some studies regarding its psychometric properties have been published. However, investigations on the factorial validity of the CRAFFT ...
journal_title：Addictive behaviors
pub_type： 杂志文章
doi：10.1016/j.addbeh.2016.03.020
更新日期：2016-08-01 00:00:00
abstract：INTRODUCTION:The smoking behavior of adults can negatively impact children through exposure to environmental tobacco smoke and by modeling this unhealthy behavior. Little research has examined the role of the social environment in smoking behaviors of adults living with children. The present study specifically analyzed...
journal_title：Addictive behaviors
pub_type： 杂志文章
doi：10.1016/j.addbeh.2015.10.022
更新日期：2016-02-01 00:00:00
abstract：:Given the documented association between paternal alcoholism and negative parenting behaviors, the purpose of this study was to examine longitudinally whether marital satisfaction mediates this relationship. Participants consisted of 197 families (102 without an alcoholic father, 95 with an alcoholic father) who were ...
journal_title：Addictive behaviors
pub_type： 杂志文章
doi：10.1016/j.addbeh.2009.05.003
更新日期：2009-11-01 00:00:00
abstract：:Comorbid substance use and posttraumatic stress disorders (SUD-PTSD) predict poorer treatment outcomes. Self-medication has been forwarded as a symptom-level explanatory model. However, research has yet to be conducted that can provide detailed examination of SUD and PTSD symptom fluctuations over time as posited by s...
journal_title：Addictive behaviors
pub_type： 杂志文章
doi：10.1016/j.addbeh.2009.08.009
更新日期：2010-01-01 00:00:00
abstract：:The Substance Use Risk Profile Scale (SURPS) is based on a model of personality risk for substance abuse in which four personality dimensions (hopelessness, anxiety sensitivity, impulsivity, and sensation seeking) are hypothesized to differentially relate to specific patterns of substance use. The current series of st...
journal_title：Addictive behaviors
pub_type： 杂志文章
doi：10.1016/j.addbeh.2009.07.001
更新日期：2009-12-01 00:00:00
abstract：:Clients with severe mental illness and substance use disorder (i.e., dual disorders) frequently have contact with family members, who may provide valuable emotional and material support, but have limited skills and knowledge to promote recovery. Furthermore, high levels of family conflict and stress are related to hig...
journal_title：Addictive behaviors
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1016/j.addbeh.2009.03.025
更新日期：2009-10-01 00:00:00
abstract：:Ample studies have established that parents as well as peers function as role models in the development of adolescents' alcohol use. The role of siblings, however, has been largely neglected despite the long-term nature of a sibling relationship. The present study examined the impact of siblings on drinking behavior o...
journal_title：Addictive behaviors
pub_type： 杂志文章
doi：10.1016/j.addbeh.2006.12.011
更新日期：2007-09-01 00:00:00
abstract：:Seventeen methadone-maintained cigarette smokers received 4 weeks of contingency management (CM) as a stop-smoking intervention. Results indicated that CM patients significantly reduced breath CO levels from baseline to completion of treatment and that 23.4% of patients maintained 1 week or more of continued smoking a...
journal_title：Addictive behaviors
pub_type： 杂志文章
doi：10.1016/0306-4603(95)00066-6
更新日期：1996-05-01 00:00:00
abstract：BACKGROUND:Smoking quit intentions (i.e., plans or commitments to reduce smoking) are distinct from quit motivation (i.e., desire to quit). Motivation to quit is a dynamic avoidance motivational state, likely subject to frequent fluctuations and shifts based on environmental context, similar to craving (an approach mot...
journal_title：Addictive behaviors
pub_type： 杂志文章
doi：10.1016/j.addbeh.2019.04.012
更新日期：2019-09-01 00:00:00
abstract：:This present study investigated the genetic and environmental influences on the associations between adolescents' peer characteristics (i.e., peer college orientation, and peer delinquency) and smoking in young adulthood. We used longitudinal data from the Nonshared Environment and Adolescent Development (NEAD) projec...
journal_title：Addictive behaviors
pub_type： 杂志文章
doi：10.1016/j.addbeh.2008.02.017
更新日期：2008-09-01 00:00:00
abstract：INTRODUCTION:Some fear that distribution of naloxone to persons at risk of experiencing an opioid overdose may reduce the perceived negative consequences of drug use, leading to riskier patterns of use. This study assessed whether participation in naloxone/overdose training altered drug use frequency, quantity or sever...
journal_title：Addictive behaviors
pub_type： 杂志文章
doi：10.1016/j.addbeh.2017.03.008
更新日期：2017-08-01 00:00:00
abstract：:Adolescents who use aggressive tactics to handle interpersonal conflicts may be at high risk for substance use, while adolescents who possess coping strategies to avoid or manage interpersonal conflict may be at lower risk for substance use. This study examined the association between interpersonal conflict tactics an...
journal_title：Addictive behaviors
pub_type： 杂志文章
doi：10.1016/s0306-4603(01)00290-8
更新日期：2003-07-01 00:00:00
abstract：:The efficacy of the Alcohol Skills Training Program (ASTP; Miller, et al., 2000) was evaluated in 204 heavy-drinking college students randomly assigned to either ASTP (n=119) or an assessment-only control (n=85) condition. The volunteer ASTP sample (n=119) was also compared to a sample of students mandated to ASTP fol...
journal_title：Addictive behaviors
pub_type： 杂志文章
doi：10.1016/j.addbeh.2010.08.009
更新日期：2010-12-01 00:00:00
abstract：:Electronic nicotine delivery systems (ENDS) have been gaining in popularity. The few prevalence studies in adults have found that most ENDS users are current or former smokers. The objectives of this study were to estimate the prevalence of ENDS usage in adolescents, and examine the correlates of use. Self-administere...
journal_title：Addictive behaviors
pub_type： 杂志文章
doi：10.1016/j.addbeh.2013.09.014
更新日期：2014-01-01 00:00:00
abstract：UNLABELLED:Social norms approaches (SNA) are based on the premise that we frequently overestimate risk behaviours among our peers. By conducting campaigns to reduce these misperceptions, SNAs aim to reduce risk behaviours. This study examines the extent to which 12 to 13year old pupils overestimate smoking among their ...
journal_title：Addictive behaviors
pub_type： 杂志文章
doi：10.1016/j.addbeh.2014.09.015
更新日期：2015-02-01 00:00:00
abstract：AIMS:To explore reciprocal relationships between real-time gambling cravings and self-efficacy with gambling behaviour, and the moderating role of gambling, mental health, and addiction-related variables. DESIGN:Secondary analysis of a 4-week Ecological Momentary Assessment (EMA) study conducted in Tasmania, Australia...
journal_title：Addictive behaviors
pub_type： 杂志文章
doi：10.1016/j.addbeh.2020.106574
更新日期：2021-01-01 00:00:00
abstract：:Arousal-based theories of gambling suggest that excitement gained from gambling reinforces further gambling behavior. However, recent theories of emotion conceptualize mood as comprising both arousal and valence dimensions. Thus, excitement comprises arousal with positive valence. We examined self-reported changes in ...
journal_title：Addictive behaviors
pub_type： 杂志文章
doi：10.1016/j.addbeh.2004.03.030
更新日期：2004-12-01 00:00:00
abstract：:It is common in addictions research for statistical analyses to include interaction effects to test moderation hypotheses. Far less commonly do researchers consider the possibility that a given predictor may exert a nonlinear effect on the outcome. This lack of attention to the possible nonlinear effects of individual...
journal_title：Addictive behaviors
pub_type： 杂志文章
doi：10.1016/j.addbeh.2018.09.018
更新日期：2019-07-01 00:00:00
abstract：:Self-reports continue to be the most commonly used method in studies on the effectiveness of treatments for drug addiction. Nevertheless, the validity of this procedure has been called into question, so that subjects' reports are often compared with data from other sources. This study compares the data collected from ...
journal_title：Addictive behaviors
pub_type： 杂志文章
doi：10.1016/s0306-4603(02)00219-8
更新日期：2003-08-01 00:00:00
abstract：:Public opinion has been one factor affecting change in policies designed to reduce underage alcohol use. Extant research, however, has been criticized for using single survey items of unknown reliability to define adult attitudes on alcohol policy issues. The present investigation addresses a critical gap in the liter...
journal_title：Addictive behaviors
pub_type： 杂志文章
doi：10.1016/s0306-4603(01)00223-4
更新日期：2003-03-01 00:00:00
abstract：:Building upon previous research establishing a positive association between grandiose and vulnerable narcissism and problematic social networking use, the present study tests a model that explains how grandiose and vulnerable narcissists might develop Facebook (Fb) addiction symptoms through the need for admiration an...
journal_title：Addictive behaviors
pub_type： 杂志文章
doi：10.1016/j.addbeh.2017.08.038
更新日期：2018-01-01 00:00:00
abstract：:At any point in time, a patient's return to drug use can be seen either as a temporary event or as a return to persistent use. There is no formal standard for distinguishing persistent drug use from an occasional relapse. This lack of standardization persists although the consequences of either interpretation can be l...
journal_title：Addictive behaviors
pub_type： 杂志文章
doi：10.1016/j.addbeh.2004.02.027
更新日期：2004-06-01 00:00:00
abstract：:The authors carried out a comparative study on two groups of heroin abusers treated in several therapeutic communities: One group consumed heroin on at least three occasions between the fifth and sixth months of treatment (n = 130), and the other continued without consuming heroin after 7 months of treatment (n = 130)...
journal_title：Addictive behaviors
pub_type： 杂志文章
doi：10.1016/s0306-4603(97)00037-3
更新日期：1998-03-01 00:00:00
abstract：AIMS:To describe the categories employed by researchers to describe adolescents' smoking behavior and to determine how these various categorizations compare with youths' self-defined smoking status. STUDY SELECTION:A search of the PubMed and Science Direct databases, limited to articles in the English language, publis...
journal_title：Addictive behaviors
pub_type： 杂志文章
doi：10.1016/j.addbeh.2009.05.012
更新日期：2009-11-01 00:00:00
abstract：:Relative to adults, adolescents are at greater risk of developing a cannabis use disorder (CUD) and risk may be exacerbated by co-occurring depressive symptoms. N-Acetylcysteine (NAC), an over-the-counter antioxidant, is thought to normalize glutamate transmission. Oxidative stress and glutamate transmission are disru...
journal_title：Addictive behaviors
pub_type： 杂志文章
doi：10.1016/j.addbeh.2018.05.014
更新日期：2018-10-01 00:00:00
abstract：:Mobile apps provide a highly accessible way of reducing alcohol use in young people. This paper determines the 1-month efficacy and 2, 3 and 6month outcomes of the Ray's Night Out app, which aims to increase alcohol knowledge and reduce alcohol use in young people. User-experience design and agile development processe...
journal_title：Addictive behaviors
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.addbeh.2017.09.020
更新日期：2018-02-01 00:00:00
