Abstract:
BACKGROUND:This is the first study to examine predictors of successful cessation in African American (AA) light smokers treated within a placebo-controlled trial of bupropion. METHODS:We analyzed data from a randomized, double-blind, placebo-controlled trial of bupropion and health education for 540 African American light smokers. African American light smokers (≤10 cigarettes per day, cpd) were randomly assigned to receive 150mg bid bupropion SR (n=270) or placebo (n=270) for 7weeks. All participants received health education counseling at weeks 0, 1, 3, 5 and 7. Using chi-square tests, two sample t-tests, and multiple logistic regression analyses, we examined baseline psychosocial and smoking characteristics as predictors of cotinine-verified 7-day point prevalence smoking abstinence among study participants at the end treatment (Week 7) and at the end of follow-up (Week 26). RESULTS:Participants who received bupropion were significantly more likely to quit smoking compared to those who received placebo (OR=2.72, 95% CI=1.60-4.62, P=0.0002). Greater study session attendance (OR=2.47, 95% CI=1.76-3.46, P=0.0001), and smoking non-menthol cigarettes increased the likelihood of quitting (OR=1.84, 95% CI=1.01-3.36, P=0.05); while longer years of smoking (OR=0.98, 95% CI=0.96-1.00, P=0.05) and higher baseline cotinine (OR=0.97, 95% CI=0.95-0.99, P=0.002) significantly reduced the odds of quitting at Week 7. Conversely, at the end of follow-up (Week 26), treatment with bupropion vs. placebo (OR=1.14, 95% CI=0.65-2.02, P=0.64) was not significantly associated with quitting and type of cigarette smoked (menthol vs. non-menthol) did not appear in the final logistic regression model. Greater study session attendance (OR=1.96, 95% CI=1.44-2.66, P=0.0001); BMI (OR=1.03, 95% CI=1.00-1.07, P=0.04); and weight efficacy (OR=1.03, 95% CI=1.01-1.05, P=0.01) increased the likelihood of quitting at Week 26. Similar to our findings at Week 7, longer years of smoking (OR=0.96, 95% CI=0.94-0.99, P=0.01) and higher baseline cotinine (OR=0.97, 95% CI=0.95-0.99, P=0.02) significantly reduced the odds of quitting at Week 26. CONCLUSIONS:Baseline cotinine levels, number of years smoked and study session attendance are associated with both short- and long-term smoking cessation, while bupropion and the type of cigarette smoked were associated with quitting on short term only.
journal_name
Addict Behavjournal_title
Addictive behaviorsauthors
Faseru B,Nollen NL,Mayo MS,Krebill R,Choi WS,Benowitz NL,Tyndale RF,Okuyemi KS,Ahluwalia JS,Sanderson Cox Ldoi
10.1016/j.addbeh.2012.11.010subject
Has Abstractpub_date
2013-03-01 00:00:00pages
1796-803issue
3eissn
0306-4603issn
1873-6327pii
S0306-4603(12)00383-8journal_volume
38pub_type
杂志文章,随机对照试验abstract:INTRODUCTION:Some fear that distribution of naloxone to persons at risk of experiencing an opioid overdose may reduce the perceived negative consequences of drug use, leading to riskier patterns of use. This study assessed whether participation in naloxone/overdose training altered drug use frequency, quantity or sever...
journal_title:Addictive behaviors
pub_type: 杂志文章
doi:10.1016/j.addbeh.2017.03.008
更新日期:2017-08-01 00:00:00
abstract::The consistency of the tobacco withdrawal syndrome across repeated periods of abstinence was tested using a modified A-B-A-B design. The large majority of the signs and symptoms of tobacco withdrawal occurred during abstinence, returned to baseline, and then recurred during a second abstinence period. This finding sug...
journal_title:Addictive behaviors
pub_type: 杂志文章
doi:10.1016/0306-4603(84)90043-1
更新日期:1984-01-01 00:00:00
abstract:PURPOSE:Data from the Collaborative Study on the Genetics of Alcoholism (COGA), a high-risk family study of alcohol dependence, were used to examine differences in alcohol diagnostic criteria endorsement and psychiatric and drug use disorders by gender and by number of DUI offenses. RESULTS:Individuals with two or mor...
journal_title:Addictive behaviors
pub_type: 杂志文章,多中心研究
doi:10.1016/j.addbeh.2008.12.003
更新日期:2009-05-01 00:00:00
abstract::Results from a study using the balanced placebo design to assess alcohol's effects on anxiety raise serious doubts about the utility of the design even at moderate blood alcohol concentrations. Despite being informed that they were not drinking alcohol, 44% of the subjects who were administered alcohol reported consum...
journal_title:Addictive behaviors
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/0306-4603(94)90034-5
更新日期:1994-05-01 00:00:00
abstract::Individuals at high risk for alcoholism have been hypothesized to acquire alcoholic characteristics more rapidly than those at low risk. Two studies examined reactivity to alcohol cues, a phenomenon linked to craving for alcohol in clinical alcoholics, and ad lib drinking behavior in young men at varying risk for alco...
journal_title:Addictive behaviors
pub_type: 杂志文章
doi:10.1016/0306-4603(90)90005-i
更新日期:1990-01-01 00:00:00
abstract::The objective of the present study was to examine the properties of a modification of the Fagerström Test of Nicotine Dependence in a large sample of smokeless tobacco (ST) users. The subjects for this study included 256 males who were recruited for a tobacco cessation intervention that involved a visit with a dentist...
journal_title:Addictive behaviors
pub_type: 杂志文章
doi:10.1016/j.addbeh.2007.01.005
更新日期:2007-09-01 00:00:00
abstract:INTRODUCTION:Efforts to understand how adolescents acquire marijuana will help to contextualize its use among youth. Little is known about ways of getting marijuana and how they differ between subgroups of adolescents. The present study sought to determine how adolescents get marijuana and if modes of access vary by so...
journal_title:Addictive behaviors
pub_type: 杂志文章
doi:10.1016/j.addbeh.2020.106730
更新日期:2021-03-01 00:00:00
abstract::Most investigators have not adequately accounted for the alcohol content of different beverages when assessing alcohol consumption. Considerable research has assessed consumption in terms of the number of standard drinks. A problem with standard drink measures is that different distilled spirits, wines, and malt bever...
journal_title:Addictive behaviors
pub_type: 杂志文章
doi:10.1016/0306-4603(91)90064-o
更新日期:1991-01-01 00:00:00
abstract::The present study is an attempt to identify responses to alcohol-related stimuli which might differentiate alcoholics from non-alcoholics. The assumption was that alcoholics would be more reactive to alcohol cues because of prior conditioning history with respect to alcohol and drinking. Eight alcoholics in treatment ...
journal_title:Addictive behaviors
pub_type: 杂志文章
doi:10.1016/0306-4603(83)90048-5
更新日期:1983-01-01 00:00:00
abstract::Problem gambling has been linked to impairments in decision-making under uncertainty. Problem gamblers are more likely to favor high-risk, high-reward, and short-term gains over more advantageous choice alternatives, and this preference has been linked to impaired learning about decision outcomes. In this paper we lin...
journal_title:Addictive behaviors
pub_type: 杂志文章
doi:10.1016/j.addbeh.2020.106496
更新日期:2020-11-01 00:00:00
abstract::While much is known about alcohol use in adolescence and beyond, factors leading to such behaviors are rooted much earlier in life. To investigate what preschoolers (aged three to six) know about alcohol and adult alcohol use, we developed an electronic version (eABT) of the Appropriate Beverage Task (Zucker, Kincaid,...
journal_title:Addictive behaviors
pub_type: 杂志文章
doi:10.1016/j.addbeh.2016.05.004
更新日期:2016-10-01 00:00:00
abstract:INTRODUCTION:The CRAFFT questionnaire is a widely utilized measure of problematic alcohol and drug use. The brief screening instrument has been translated into multiple languages, and some studies regarding its psychometric properties have been published. However, investigations on the factorial validity of the CRAFFT ...
journal_title:Addictive behaviors
pub_type: 杂志文章
doi:10.1016/j.addbeh.2016.03.020
更新日期:2016-08-01 00:00:00
abstract::Several procedures have been developed to measure body image distortion. A recently developed device is the Body Image Detection Device (BIDD), which includes a measure of perceptual size distortion (BPI) and subjective ratings of relative weight (SRI). Initial studies have supported the validity and reliability of th...
journal_title:Addictive behaviors
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/0306-4603(92)90017-p
更新日期:1992-01-01 00:00:00
abstract::The overlap of gaming and gambling activities within online digital technologies is of growing relevance to the study of technological addictions. Social casino games are immensely popular 'free to play' games that offer realistic emulation of financial gambling activities. Their structural similarities might suggest ...
journal_title:Addictive behaviors
pub_type: 杂志文章
doi:10.1016/j.addbeh.2015.12.007
更新日期:2017-01-01 00:00:00
abstract::The present paper draws on the diffusion of innovations model to derive a series of strategies for speeding up the spread and implementation of new ideas in preventing addiction. Preventive innovations usually require an action at one point in time in order to avoid an unwanted future condition. Hence, preventive inno...
journal_title:Addictive behaviors
pub_type: 杂志文章
doi:10.1016/s0306-4603(02)00300-3
更新日期:2002-11-01 00:00:00
abstract::The primary aim of this study was to examine gender differences in perceived risks and benefits of smoking cessation and their relationship to pretreatment motivation and treatment outcome. No validated measures that comprehensively assess perceived risks and benefits associated with smoking cessation were available i...
journal_title:Addictive behaviors
pub_type: 杂志文章
doi:10.1016/j.addbeh.2004.05.027
更新日期:2005-03-01 00:00:00
abstract::Research indicates stress, craving and menstrual phase may play a role in relapse to smoking. It remains unknown how these factors may interact during cessation. This study describes the relationship between craving and cortisol concentrations by menstrual phase during ad libitum smoking and investigates the impact of...
journal_title:Addictive behaviors
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.addbeh.2009.03.024
更新日期:2009-08-01 00:00:00
abstract::Considerable research has focused on patterns of substance use initiation among adolescents and for users of selected drugs; however, few data are available for methamphetamine (MA) users. This study describes substance initiation patterns for 352 MA users and assesses predictors of age of MA initiation and its sequen...
journal_title:Addictive behaviors
pub_type: 杂志文章
doi:10.1016/j.addbeh.2006.03.017
更新日期:2007-01-01 00:00:00
abstract::The possible impact of menstrual phase upon reactivity to nicotine was investigated in 12 healthy women smokers. Controlled doses of nicotine were administered via an intranasal aerosol delivery device to overnight-deprived women smokers in four hormonally verified menstrual phases. Physiological, biochemical, and sub...
journal_title:Addictive behaviors
pub_type: 杂志文章
doi:10.1016/s0306-4603(98)00033-1
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abstract:INTRODUCTION:Changes to the U.S. smokeless tobacco landscape in recent years include a change to health warnings on packages, the implementation of bans in some stadiums, and the launch of a federal youth prevention campaign. It is unclear whether such changes have impacted consumer beliefs about smokeless tobacco. Thi...
journal_title:Addictive behaviors
pub_type: 杂志文章
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abstract::Alcoholics are thought to be characterized by irregular emotional responses, having trouble reaching an optimal level of emotional arousal. They therefore may use alcohol to restore emotional homeostasis. This study investigated whether recently detoxified alcoholics show different emotional responses as compared to c...
journal_title:Addictive behaviors
pub_type: 杂志文章
doi:10.1016/s0306-4603(97)00040-3
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abstract::Families play a critical role in supporting adolescents with substance use disorders. Little research has been done to investigate interventions targeting the significant stress of caring for an adolescent with problematic substance use and its subsequent impact on self-compassion in families. The aim of this pilot st...
journal_title:Addictive behaviors
pub_type: 杂志文章
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更新日期:2020-04-01 00:00:00
abstract::Although motivational models of alcohol use often invoke constructs relevant to affective distress (e.g., depressive symptoms), to date, no study has assessed the potential role of cognitive structures (enduring cognitive belief systems) in promoting problematic drinking behavior. Thus, the current study evaluated the...
journal_title:Addictive behaviors
pub_type: 杂志文章
doi:10.1016/j.addbeh.2008.10.011
更新日期:2009-02-01 00:00:00
abstract::Numerous studies have highlighted that personality traits are associated with alcohol problems and disorders; however, little is known on the link between personality and the quantities of alcohol actually ingested during given drinking episodes (i.e. in situ alcohol consumption, in grams of pure alcohol). Based on da...
journal_title:Addictive behaviors
pub_type: 杂志文章
doi:10.1016/j.addbeh.2012.08.006
更新日期:2013-03-01 00:00:00
abstract::A significant number of young, low-income women experiment with ecstasy outside of club or rave settings. The current study examined patterns and risk factors of ecstasy use among this group of women. A cross-sectional survey was conducted among 696 women aged 18 to 31 who sought gynecological care from two university...
journal_title:Addictive behaviors
pub_type: 杂志文章
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journal_title:Addictive behaviors
pub_type: 杂志文章
doi:10.1016/j.addbeh.2017.10.026
更新日期:2018-03-01 00:00:00
abstract::Existing research has demonstrated the significance of situational antecedents to substance use. The current study used a cluster analytic approach to identify groups of club drug users who report using substances in similar situations (assessed by the Inventory of Drug Taking Situations) with longitudinal data from 4...
journal_title:Addictive behaviors
pub_type: 杂志文章
doi:10.1016/j.addbeh.2010.07.007
更新日期:2010-12-01 00:00:00
abstract::This paper presents a model for the development of a comprehensive, multilevel, preventively-oriented parenting and family support strategy to reduce family risk factors associated with drug abuse in young people. If parenting interventions are to make a significant impact at a population level on the prevalence of dy...
journal_title:Addictive behaviors
pub_type: 杂志文章
doi:10.1016/s0306-4603(00)00128-3
更新日期:2000-11-01 00:00:00
abstract:OBJECTIVE:To assess whether perceived changes in postpartum support were associated with postpartum return to smoking. STUDY DESIGN:This is a prospective repeated measures, mixed methods observational study. Sixty-five women who smoked prior to pregnancy were recruited at delivery and surveyed at 2, 6, 12, and 24 week...
journal_title:Addictive behaviors
pub_type: 杂志文章
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journal_title:Addictive behaviors
pub_type: 杂志文章
doi:10.1016/j.addbeh.2010.08.023
更新日期:2011-01-01 00:00:00