The radiosensitive effect of apatinib for hepatocellular carcinoma patient with big paraspinal metastasis: A case report.

Abstract:

RATIONALE:Hepatocellular carcinoma (HCC) is a highly invasive cancer associated with great mortality rates. The prognosis of advanced HCC is very poor. PATIENT CONCERNS:Here, we report a HCC patient with a big paraspinal metastasis with 10 cm in diameter who failed the treatment of sorafenib. DIAGNOSES:Sorafenib refractory HCC with big paraspinal metastasis. INTERVENTIONS:The concurrent treatment of apatinib with stereotactic body radiotherapy (SBRT). OUTCOMES:The paraspinal metastasis with 10 cm in diameter showed nearly complete response. LESSONS:We think that the apatinib may be a good choice for HCC and it may function as a radiosensitizer of HCC. However, it warrants further investigation in the future prospective clinical studies.

journal_name

Medicine (Baltimore)

journal_title

Medicine

authors

Zhu H,Zhao Y,Wang X

doi

10.1097/MD.0000000000009598

subject

Has Abstract

pub_date

2018-01-01 00:00:00

pages

e9598

issue

2

eissn

0025-7974

issn

1536-5964

pii

00005792-201801120-00040

journal_volume

97

pub_type

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