Prospective and comparative study of paroxysmal nocturnal hemoglobinuria patients treated or not by eculizumab: Focus on platelet extracellular vesicles.

abstract：:Nuclear factor-κB-inducing kinase (NIK) is a new regulator of nuclear factor-κB signaling, which plays an important role in tumorigenesis. This study aimed to examine the expression of NIK in gastric cancer and investigate its clinical significance.Tumor issues were collected from 80 gastric cancer patients who receiv...

journal_title：Medicine

authors： Teng H,Xue L,Wang Y,Ding X,Li J

更新日期：2020-01-01 00:00:00

abstract：:The aim of the study was to examine whether depression impacts medication nonadherence (MNA) over time and determine if race has a differential impact on MNA in patients with type 2 diabetes and comorbid depression.Generalized estimating equations were used with a longitudinal national cohort of 740,197 veterans with ...

journal_title：Medicine

authors： Axon RN,Gebregziabher M,Hunt KJ,Lynch CP,Payne E,Walker RJ,Egede LE

更新日期：2016-06-01 00:00:00

abstract：BACKGROUND:Intrahepatic cholestasis of pregnancy (ICP) is a specific pregnancy-related disorder without standard medical therapies. Ursodeoxycholic acid (UDCA) is the most used medicine, but the efficacy and safety of UDCA remain uncertain. Several meta-analyses had been made to assess the effects of UDCA in ICP. Howev...

journal_title：Medicine

authors： Kong X,Kong Y,Zhang F,Wang T,Yan J

更新日期：2016-10-01 00:00:00

abstract：:Satisfaction with life in the case of nurses is closely related to their professional work and is an important factor affecting the quality of work and patient care.An analysis of the readiness of Polish nurses depending on the level of life satisfaction.The study was conducted from January to November 2016 in randoml...

journal_title：Medicine

authors： Marć M,Bartosiewicz A,Burzyńska J,Binkowska-Bury M,Januszewicz P

更新日期：2018-09-01 00:00:00

abstract：:The aim of this study was to assess the stress-related responses and the coach's capability to match perceived efforts of youth athletes during a taekwondo championship.Using a cross-sectional study design, salivary cortisol (sC) and alpha-amylase (sAA) were measured in 6 males and 3 females young (11.0 ± 0.9 years) a...

journal_title：Medicine

authors： Capranica L,Condello G,Tornello F,Iona T,Chiodo S,Valenzano A,De Rosas M,Messina G,Tessitore A,Cibelli G

更新日期：2017-07-01 00:00:00

abstract：RATIONALE:Although capillary hemangiomas, common lesions involving the proliferation of small capillary vessels and a single layer of endothelial cells, can arise in any organ, they are rarely reported in the greater or lesser omentum. Here in, we report a case of capillary hemangioma arising from the lesser omentum in...

journal_title：Medicine

authors： Nagano H,Goi T,Taguchi S,Tsubaki T,Tsuchiyama T,Uematsu H,Noriki S

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:The best treatment option for patients with post-hemorrhagic hydrocephalus (PHH) remains controversial. The objective of the current meta-analysis is to systematically evaluate the long-term outcomes of patients with PHH treated by ventriculoperitoneal shunt (VPS) and lumboperitoneal shunt (LPS). METHODS:We...

journal_title：Medicine

authors： Sun T,Guan J,You C,Yang J,Li X,Yuan Y,Zhou Y

更新日期：2020-08-07 00:00:00

abstract：:As detection rates of non-albicans Candida species are increasing, determining their pathogen profiles and antifungal susceptibilities is important for antifungal treatment selection. We identified the antifungal susceptibility patterns and predictive factors for mortality in candidemia.A multicenter retrospective ana...

journal_title：Medicine

authors： Jung IY,Jeong SJ,Kim YK,Kim HY,Song YG,Kim JM,Choi JY

更新日期：2020-03-01 00:00:00

abstract：BACKGROUND:High mobility group box 1 (HMGB1) is a kind of proinflammatory mediator to stimulate the innate and adaptive immune system and participates in a number of acute and chronic inflammatory processes after sterile injury or microbial invasion. HMGB1 has been suggested to be involved in the pathogenesis of many a...

journal_title：Medicine

authors： Zhu B,Zhu Q,Li N,Wu T,Liu S,Liu S

更新日期：2018-07-01 00:00:00

abstract：:Familial Mediterranean Fever is a rare disease which usually begins in childhood and occurs primarily among persons of Mediterranean ancestry. It is characterized by short, self-limited, febrile episodes that may occur alone or with inflammation of serosal surfaces. Some individuals may exhibit an erysipilas-like eryt...

journal_title：Medicine

authors： Meyerhoff J

更新日期：1980-01-01 00:00:00

abstract：RATIONALE:The superior sagittal sinus (SSS) and transverse sinus are the major dural sinuses that receive a considerable amount of venous drainage. The occlusion of them has been suggested to cause intracranial hypertension, hemorrhage, and lead to potentially fatal consequences. PATIENT CONCERNS:We reported a 35-year...

journal_title：Medicine

authors： Liu Y,Li K,Huang Y,Sun J,Gao X

更新日期：2017-12-01 00:00:00

abstract：INTRODUCTION:Bilateral common iliac artery (CIA) aneurysm (CIAA) is a rare entity. In the past decade, different endovascular approaches have been adopted for patients with several comorbidities or unfit for open repair (OR). Recently, the use of iliac branch stent graft has been proposed, resulting in satisfactory pat...

journal_title：Medicine

authors： Ardita V,Giaquinta A,Veroux M,Sanfiorenzo A,Virgilio C,D'Arrigo G,Veroux P

更新日期：2017-02-01 00:00:00

abstract：BACKGROUND AND AIM:Several studies have identified that obesity and being overweight can increase the risk of developing myocardial infarction (MI). However, the predictive value of the central obesity index, that is, the waist-hip ratio (WHR), regarding MI risk remains unclear. This study aimed to provide a systematic...

journal_title：Medicine

authors： Cao Q,Yu S,Xiong W,Li Y,Li H,Li J,Li F

更新日期：2018-07-01 00:00:00

abstract：:This study aimed to discuss the risk factors of perioperative blood transfusion after the application of proximal femoral nail antirotation (PFNA) in the treatment of elderly patients with femoral intertrochanteric fracture (FIF). Moreover, this study also aimed to analyze the causes of perioperative blood transfusion...

journal_title：Medicine

authors： Dai CQ,Wang LH,Zhu YQ,Xu GH,Shan JB,Huang WC,Wei LH,Zhou FL,Li Y

更新日期：2020-04-01 00:00:00

abstract：RATIONALE:Situs invsersus totalis (SIT) is a rare anomaly featured by complete inversion of abdominal and thoracic organs. Adrenal metastasis is often encountered as part of advanced systemic dissemination, which is usually unresectable. Few published cases reported the adrenal metastasis from gastric cancer with SIT a...

journal_title：Medicine

authors： Xue W,Li Y,Zhao Z,Li W,Wang S,Zhang M,Liu T,Wang M

更新日期：2019-04-01 00:00:00

abstract：:Pigmentary mosaicism of the (hypomelanosis of) Ito type is an umbrella term, which includes phenotypes characterized by mosaic hypopigmentation in the form of streaks, whorls, patchy, or more bizarre skin configurations (running along the lines of Blaschko): these cutaneous patterns can manifest as an isolated skin di...

journal_title：Medicine

authors： Pavone V,Signorelli SS,Praticò AD,Corsello G,Savasta S,Falsaperla R,Pavone P,Sessa G,Ruggieri M

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:Periodontitis is a common disease with an unclear pathological mechanism. No precise consensus has been reached to evaluate the association between the IL-10 rs1800872 (- 592, -590, -597 C>A) polymorphism and periodontal disease. Thus, we performed this meta-analysis to collect more evidence-based informatio...

journal_title：Medicine

authors： Wang Z,Li Y,Zhou Y,Qiao Y

更新日期：2019-10-01 00:00:00

abstract：:This study was conducted to investigate the clinicopathological features of synchronous cancers and treatment options according to their locations.Records of 8368 patients with colorectal cancer treated at our center between July 2003 and December 2010 were analyzed retrospectively. All synchronous colorectal cancer p...

journal_title：Medicine

authors： Lee BC,Yu CS,Kim J,Lee JL,Kim CW,Yoon YS,Park IJ,Lim SB,Kim JC

更新日期：2017-03-01 00:00:00

abstract：RATIONALE:Apatinib is an oral tyrosine kinase inhibitor targeting vascular endothelial growth factor receptor-2. It has been shown that apatinib is effective and safe for treatment of multiple solid tumors, including gastric cancer, liver cancer, non-small-cell lung cancer, and breast cancer. However, there is currentl...

journal_title：Medicine

authors： Chen S,Zhang K,Wan X,Chen Y,Ma S,Deng Q

更新日期：2019-12-01 00:00:00

abstract：:A few decades ago, antibiotic prophylaxis for patients with acute variceal bleeding was reported beneficial. However, endoscopic and systemic therapy for variceal bleeding has dramatically improved since then, so the necessity of prophylactic antibiotics can be questioned. In this study, we reevaluated the efficacy of...

journal_title：Medicine

authors： Ueno M,Kayahara T,Sunami T,Takayama H,Takabatake H,Morimoto Y,Yamamoto H,Mizuno M

更新日期：2020-05-01 00:00:00

abstract：RATIONALE:Glossopharyngeal neuralgia (GPN) is a rare type of neuralgia. Depending on the cause, it is classified as idiopathic GPN and secondary GPN. Secondary GPN can also be caused by a mass effect or inflammation of the tonsils, the innervation area of glossopharyngeal nerve. PATIENT CONCERNS:The patient was diagno...

journal_title：Medicine

authors： Kim E,Do W,Jung YH,Lee J,Baik J

更新日期：2019-04-01 00:00:00

abstract：:The vascular endothelial growth factor (VEGF) level in human circulation may reflect the severity of endothelial dysfunction in patients with diabetes mellitus, which leads to diabetic microvascular complications.We determined plasma VEGF levels as well as metabolic control and inflammatory factors in 26 healthy subje...

journal_title：Medicine

authors： Zhang Q,Fang W,Ma L,Wang ZD,Yang YM,Lu YQ

更新日期：2018-04-01 00:00:00

abstract：:Bisphenol A (BPA), a carbon-based synthetic compound, exhibits hormone-like properties and is present ubiquitously in the environment and in human tissues due to its widespread use and biological accumulation. BPA can mimic estrogen to interact with estrogen receptors α and β, leading to changes in cell proliferation,...

journal_title：Medicine

authors： Gao H,Yang BJ,Li N,Feng LM,Shi XY,Zhao WH,Liu SJ

更新日期：2015-01-01 00:00:00

abstract：:Our previous study confirmed the negative association between the development of calcarine sulcus and the width of lateral ventricles. The purpose of current study was to evaluate the reliability of calcarine sulcus depth in the 2nd trimester to predict the prenatal enlargement of lateral ventricle in fetuses with iso...

journal_title：Medicine

authors： Li H,Liu G,Lin F,Liang H

更新日期：2017-07-01 00:00:00

abstract：:The contributions of micro RNAs (miRNAs) to rheumatoid arthritis (RA) are beginning to be uncovered during the last decade. Many studies in efforts to use miRNAs as biomarkers in disease diagnosis, prognosis, and treatment are ongoing.We conducted a systematic literature review to reveal the role of miRNAs in the path...

journal_title：Medicine

authors： Chen XM,Huang QC,Yang SL,Chu YL,Yan YH,Han L,Huang Y,Huang RY

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND:Lung cancer is a leading cause of morbidity diseases worldwide, but the key mechanisms of lung cancer remain elusive. This study aims to integrate of GSE 118370 and GSE 32863 profile and identify the key genes and pathway involved in human lung adenocarcinoma. METHODS:R software (RStudio, Version info: R 3....

journal_title：Medicine

authors： Hua P,Zhang Y,Jin C,Zhang G,Wang B

更新日期：2020-10-23 00:00:00

abstract：BACKGROUND:Parkinson disease (PD) is a progressive neuromuscular disease associated with bradykinesia, tremor, and postural instability. We aimed to compare outcomes and complications of total hip arthroplasty (THA) between patients with PD and those without. METHODS:A single institution retrospective cohort from 2000...

journal_title：Medicine

authors： Zhang Y,Xiong K,Li R,Yang L

更新日期：2020-05-01 00:00:00

abstract：:The originally dismal prognosis associated with anti-GBM Ab-mediated GN and Goodpasture's syndrome may be changing as we recognize a broader spectrum of disease, improve general supportive care, and improve specific treatment. Immunosuppressive therapy, if started early in the course of disease, may prevent or allow r...

journal_title：Medicine

authors： Briggs WA,Johnson JP,Teichman S,Yeager HC,Wilson CB

更新日期：1979-09-01 00:00:00

abstract：:Periodontitis is a systemic and chronic inflammatory disease associated with multiple physical conditions. Distress and depression are other problems affecting the progression of periodontitis. However, the causal relationship between depression and periodontitis has not been adequately investigated. This aim of this ...

journal_title：Medicine

authors： Hsu CC,Hsu YC,Chen HJ,Lin CC,Chang KH,Lee CY,Chong LW,Kao CH

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:The blood glucose response to moderate-intensity exercise remains unclear for patients with type 2 diabetes (T2DM). In addition, little is known about determinants of blood glucose response to a 12-week moderate-intensity exercise training. Therefore, this study aimed to explore trends in blood glucose in re...

journal_title：Medicine

authors： Chiang SL,Heitkemper MM,Hung YJ,Tzeng WC,Lee MS,Lin CH

更新日期：2019-09-01 00:00:00