Low-level toxicity of chemicals: No acceptable levels?

Abstract:

:Over the past 3 decades, in a series of studies on some of the most extensively studied toxic chemicals and pollutants, scientists have found that the amount of toxic chemical linked with the development of a disease or death-which is central to determining "safe" or "hazardous" levels-is proportionately greater at the lowest dose or levels of exposure. These results, which are contrary to the way the United States Environmental Protection Agency (EPA) and other regulatory agencies assess the risk of chemicals, indicate that we have underestimated the impact of toxic chemicals on death and disease. If widely disseminated chemicals and pollutants-like radon, lead, airborne particles, asbestos, tobacco, and benzene-do not exhibit a threshold and are proportionately more toxic at the lowest levels of exposure, we will need to achieve near-zero exposures to protect public health.

journal_name

PLoS Biol

journal_title

PLoS biology

authors

Lanphear BP

doi

10.1371/journal.pbio.2003066

subject

Has Abstract

pub_date

2017-12-19 00:00:00

pages

e2003066

issue

12

eissn

1544-9173

issn

1545-7885

pii

pbio.2003066

journal_volume

15

pub_type

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