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The kinematics of handwriting movements as expression of cognitive and sensorimotor impairments in people with multiple sclerosis.

Abstract：

:Handwriting is an important activity of daily living, which requires sensorimotor and cognitive skills that could deteriorate in presence of neurological diseases. Handwriting impairments are common in people with multiple sclerosis (PwMS). Aims of the present study were to characterize handwriting movement features of PwMS in comparison with those of healthy adults, and to evaluate the relationship between kinematic parameters of handwriting movements and the results of the assessment of cognitive and motor domains. A new handwriting evaluation methodology was applied to quantify handwriting features of 19 PwMS and 22 age-matched healthy controls who were required to write a sentence on a digitizing tablet. Kinematic parameters of the sentence and of the strokes were used to evaluate handwriting performance. PwMS showed an altered handwriting kinematics with respect to healthy controls: higher movement duration, fragmented velocity profile and higher jerk. Furthermore, motor abilities and cognitive status of PwMS were related to handwriting parameters in accordance with the evidence that MS is a multifactorial disease affecting different domains. These results suggested that the proposed methodology might be a valuable tool to quantitatively assess handwriting impairments and the efficacy of handwriting treatments in PwMS.

journal_name

Sci Rep

journal_title

Scientific reports

authors

Bisio A,Pedullà L,Bonzano L,Tacchino A,Brichetto G,Bove M

doi

10.1038/s41598-017-18066-7

subject

Has Abstract

pub_date

2017-12-18 00:00:00

pages

17730

issue

1

issn

2045-2322

pii

10.1038/s41598-017-18066-7

journal_volume

7

pub_type

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