Abstract：
INTRODUCTION:Alcohol hangover experiences in young adulthood have been shown to predict more subsequent alcohol problems. Hangover susceptibility appears to be partially heritable and related to family history of alcohol use disorders. However, very little is known about the developmental course of these associations and whether they are accounted for by an individual's drinking history. The goal of this study is to investigate the prospective and unique relationships between family history of alcohol use disorders, severity of alcohol hangover experiences in adolescence, and later alcohol use and related problems measured over 13years. METHODS:Participants were first assessed on family history at age 12-14, prior to initiating drinking, and re-assessed annually on hangover severity, drinks per drinking day (DPDD), and alcohol-related problems throughout the 13-year follow-up period (n=205; 59% male). RESULTS:In mixed effects negative binomial regression models, greater family history density scores predicted more future DPDD (Incidence Rate Ratio [IRR]=1.19, p=0.04), alcohol problems (IRR=1.64, p=0.05), and future hangover severity (IRR=1.24; p=0.01). In turn, greater hangover severity predicted more future DPDD (IRR=1.03; p=0.002) and alcohol problems (IRR=1.12, p<0.001), and hangover severity mediated the relationship between family history and alcohol use/problems. All models controlled for participant age, sex, and past drinking behavior (where relevant). CONCLUSIONS:These results advance the alcohol hangover experience during late adolescence as a clinically relevant and uniquely informative marker of future alcohol use and problems, above and beyond that of prior personal or familial drinking history.
journal_name
Addict Behavjournal_title
Addictive behaviorsauthors
Courtney KE,Worley M,Castro N,Tapert SFdoi
10.1016/j.addbeh.2017.11.040subject
Has Abstractpub_date
2018-03-01 00:00:00pages
209-215eissn
0306-4603issn
1873-6327pii
S0306-4603(17)30448-3journal_volume
78pub_type
杂志文章abstract：BACKGROUND:Cocaine addiction and pathological gambling are commonly associated with steeper (impulsive) discounting of delayed rewards, which promotes ongoing drug and gambling behaviors. However, it is yet unclear whether impulsive delay discounting is a stable trait in cocaine and gambling disorders during abstinence...
journal_title：Addictive behaviors
pub_type： 杂志文章
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更新日期：2014-11-01 00:00:00
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journal_title：Addictive behaviors
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journal_title：Addictive behaviors
pub_type： 杂志文章
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更新日期：2014-07-01 00:00:00
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journal_title：Addictive behaviors
pub_type： 杂志文章
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journal_title：Addictive behaviors
pub_type： 杂志文章
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更新日期：1987-01-01 00:00:00
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journal_title：Addictive behaviors
pub_type： 杂志文章,评审
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journal_title：Addictive behaviors
pub_type： 杂志文章
doi：10.1016/j.addbeh.2016.10.001
更新日期：2017-02-01 00:00:00
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journal_title：Addictive behaviors
pub_type： 杂志文章
doi：10.1016/j.addbeh.2013.06.018
更新日期：2013-11-01 00:00:00
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journal_title：Addictive behaviors
pub_type： 杂志文章
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更新日期：2012-08-01 00:00:00
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journal_title：Addictive behaviors
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/j.addbeh.2004.08.010
更新日期：2005-05-01 00:00:00
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journal_title：Addictive behaviors
pub_type： 杂志文章
doi：10.1016/j.addbeh.2017.10.026
更新日期：2018-03-01 00:00:00
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journal_title：Addictive behaviors
pub_type： 杂志文章
doi：10.1016/j.addbeh.2004.02.028
更新日期：2004-11-01 00:00:00
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journal_title：Addictive behaviors
pub_type： 杂志文章
doi：10.1016/j.addbeh.2016.09.004
更新日期：2017-02-01 00:00:00
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journal_title：Addictive behaviors
pub_type： 杂志文章
doi：10.1016/j.addbeh.2020.106638
更新日期：2021-01-01 00:00:00
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journal_title：Addictive behaviors
pub_type： 杂志文章
doi：10.1016/j.addbeh.2012.02.011
更新日期：2012-06-01 00:00:00
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journal_title：Addictive behaviors
pub_type： 杂志文章
doi：10.1016/s0306-4603(02)00258-7
更新日期：2003-07-01 00:00:00
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journal_title：Addictive behaviors
pub_type： 杂志文章
doi：10.1016/j.addbeh.2011.08.013
更新日期：2012-01-01 00:00:00
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journal_title：Addictive behaviors
pub_type： 杂志文章
doi：10.1016/0306-4603(89)90024-5
更新日期：1989-01-01 00:00:00
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journal_title：Addictive behaviors
pub_type： 杂志文章
doi：10.1016/s0306-4603(00)00116-7
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journal_title：Addictive behaviors
pub_type： 杂志文章
doi：10.1016/j.addbeh.2008.10.020
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abstract：:Frequency and durational components of smoking topography were measured by a portable smoking device while 10 subjects smoked four cigarettes ad libitum in a non-laboratory environment. Nicotine blood levels were measured before and after smoking each cigarette and serial blood samples for determining nicotine metabol...
journal_title：Addictive behaviors
pub_type： 杂志文章
doi：10.1016/0306-4603(88)90031-7
更新日期：1988-01-01 00:00:00
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journal_title：Addictive behaviors
pub_type： 杂志文章
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更新日期：2000-05-01 00:00:00
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journal_title：Addictive behaviors
pub_type： 杂志文章
doi：10.1016/j.addbeh.2013.08.034
更新日期：2014-01-01 00:00:00
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journal_title：Addictive behaviors
pub_type： 杂志文章,评审
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更新日期：1997-03-01 00:00:00
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journal_title：Addictive behaviors
pub_type： 杂志文章
doi：10.1016/j.addbeh.2011.09.005
更新日期：2012-01-01 00:00:00
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journal_title：Addictive behaviors
pub_type： 杂志文章
doi：10.1016/j.addbeh.2020.106561
更新日期：2020-12-01 00:00:00
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journal_title：Addictive behaviors
pub_type： 杂志文章
doi：10.1016/s0306-4603(02)00248-4
更新日期：2003-09-01 00:00:00
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journal_title：Addictive behaviors
pub_type： 杂志文章
doi：10.1016/j.addbeh.2018.03.022
更新日期：2018-09-01 00:00:00
abstract：:Rates of smoking among individuals with psychiatric conditions are greater than rates seen in the general population, yet little is known about the psychometric properties of commonly used nicotine dependence instruments among psychiatric smokers. This study examined the reliability, validity, and factor structure of ...
journal_title：Addictive behaviors
pub_type： 杂志文章
doi：10.1016/j.addbeh.2004.09.005
更新日期：2005-06-01 00:00:00
