Abstract:
:This study examined the utility of thin layer chromatography (TLC) for detection of recent use of opioids and benzodiazepines among drug addicts seeking treatment at the Drug Dependence Treatment Centre of All India Institute of Medical Sciences, New Delhi, India. Over a period of 5 years (1991-1995), 6,055 urine samples were analyzed for opioids (morphine, codeine, buprenorphine, dextropropoxyphene, pentazocine) and benzodiazepines (diazepam, nitrazepam) by TLC. Out of all the drug tests (n = 9,922) carried out, 24% of the drugs had been used during the past 72 hr. Averaged across all drugs, the detection rates corresponding to 24, 48, and 72 hr by TLC were 37%, 36%, and 31%, respectively. A high percentage of negative TLC results was observed in these samples. Moderate sensitivity of the TLC assay procedure, low consumption of drug, short time between drug use and urine collection, overreporting by the subjects, and drug use history of the subject obtained from multiple sources led to high negative results. These findings suggest that all the TLC negative results also need further confirmation by an alternative, more sensitive technique in a clinical setting. This will make the drug abuse testing program more meaningful.
journal_name
Addict Behavjournal_title
Addictive behaviorsauthors
Jain Rdoi
10.1016/s0306-4603(99)00015-5keywords:
subject
Has Abstractpub_date
2000-05-01 00:00:00pages
451-4issue
3eissn
0306-4603issn
1873-6327pii
S0306-4603(99)00015-5journal_volume
25pub_type
杂志文章abstract::The purpose of this study was to examine the relationship of treatment outcomes in opioid detoxification to levels of counselor and peer alliance. Forty-one subjects were recruited from a larger, 180-day study of psychosocial treatment. Beginning at day 90, subjects completed monthly measures of alliance. Outcome meas...
journal_title:Addictive behaviors
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/0306-4603(94)00080-i
更新日期:1995-05-01 00:00:00
abstract::The role of the endocannabinoid system in nicotine addiction is being increasingly acknowledged. We conducted a pilot, randomised double blind placebo controlled study set out to assess the impact of the ad-hoc use of cannabidiol (CBD) in smokers who wished to stop smoking. 24 smokers were randomised to receive an inh...
journal_title:Addictive behaviors
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.addbeh.2013.03.011
更新日期:2013-09-01 00:00:00
abstract:BACKGROUND:The prevalence of electronic cigarette use has grown over the past decade, with some users reportedly initiating e-cigarette use primarily due to flavors. This study examined the role of flavors in initiation among adult e-cigarette users, as well as the association of flavors with satisfaction and perceived...
journal_title:Addictive behaviors
pub_type: 杂志文章
doi:10.1016/j.addbeh.2019.106077
更新日期:2019-12-01 00:00:00
abstract::This study examined relations between personal strivings and alcohol use among college students. Personal strivings are ongoing goals that individuals are characteristically trying to achieve through their behavior. Participants generated lists of personal strivings following standard instructions and then completed a...
journal_title:Addictive behaviors
pub_type: 杂志文章
doi:10.1016/j.addbeh.2004.02.006
更新日期:2004-06-01 00:00:00
abstract:BACKGROUND:Prior research indicates that Latino immigrants are less likely than US-born individuals to use alcohol and meet criteria for an alcohol use disorder. However, our understanding of alcohol-related problem behaviors among Latino immigrants remains limited. We report the prevalence of alcohol-related problem b...
journal_title:Addictive behaviors
pub_type: 杂志文章
doi:10.1016/j.addbeh.2018.06.031
更新日期:2018-12-01 00:00:00
abstract:INTRODUCTION:PLHIV have higher rates of smoking and lower motivation to quit smoking; thus to impact smoking rates, cessation interventions need to be acceptable to a wider range of PLHIV smokers as well as feasible to implement in a busy clinical setting. The purpose of this study was to evaluate the acceptability, fe...
journal_title:Addictive behaviors
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.addbeh.2013.05.003
更新日期:2013-10-01 00:00:00
abstract::This study examined the frequency of substance use among 14- to 24-year-old homeless youth (N=113) recruited from two community drop-in centers and explored the relationship between substance use and hypothesized psychosocial predictors. Audio-computer-assisted self-interviewing (A-CASI) was used for assessment. Inclu...
journal_title:Addictive behaviors
pub_type: 杂志文章
doi:10.1016/j.addbeh.2004.10.006
更新日期:2005-07-01 00:00:00
abstract::A number of risk factors have emerged as important correlates of adolescent substance use. In addition, research continues to focus on which factors act as mediators protecting adolescents from negative outcomes. One of these protective factors is religiosity, and the focus of this paper is to examine its role in the ...
journal_title:Addictive behaviors
pub_type: 杂志文章
doi:10.1016/j.addbeh.2004.03.022
更新日期:2004-08-01 00:00:00
abstract::Functional neuroimaging studies of cue-elicited craving in smokers have identified a distributed system of brain activation which includes the frontal cortex. As electroencephalographic (EEG) activity recorded from frontal brain regions indexes emotive functions, which are believed to play a key role in craving proces...
journal_title:Addictive behaviors
pub_type: 杂志文章
doi:10.1016/j.addbeh.2007.11.006
更新日期:2008-04-01 00:00:00
abstract::Contingency management interventions effectively reduce or eliminate some individuals' problem substance use. Typically, those who do not benefit never experience the reward or planned contingency available through the intervention because they never produce the behavior (often abstinence) on which the reward is conti...
journal_title:Addictive behaviors
pub_type: 杂志文章
doi:10.1016/j.addbeh.2003.08.021
更新日期:2004-05-01 00:00:00
abstract::The present study examined whether drinking motivations and depressive symptoms would have a stronger impact on alcohol-related problems among adult children of alcoholics (ACOAs) and their dating partners as compared to non-ACOAs and their dating partners. Participants were 197 undergraduate (60 ACOAs, 137 non-ACOAs)...
journal_title:Addictive behaviors
pub_type: 杂志文章
doi:10.1016/j.addbeh.2013.08.037
更新日期:2014-01-01 00:00:00
abstract:BACKGROUND:Age of onset is an important factor in the development and trajectory of psychiatric disorders; however, little is known regarding the age of onset in relation to disordered gambling in treatment seeking samples in the UK. Utilising a large residential treatment seeking gambler cohort, the current study exam...
journal_title:Addictive behaviors
pub_type: 杂志文章
doi:10.1016/j.addbeh.2019.05.013
更新日期:2019-10-01 00:00:00
abstract:BACKGROUND:Little is known about the influence of online peer interactions on health behavior change. This study examined the relationship between exposure to peer sentiment about nicotine replacement therapy (NRT) in an online social network for smoking cessation and NRT use. METHODS:Participants were 3297 current sm...
journal_title:Addictive behaviors
pub_type: 杂志文章
doi:10.1016/j.addbeh.2018.06.022
更新日期:2018-12-01 00:00:00
abstract::Friends are presumed to exert a substantial influence on young people's drinking patterns. The current study focused on the effects of the best friend's drinking behaviour on the alcohol consumption of 12-14-year-old adolescents. Furthermore, we hypothesized friendship characteristics (i.e., reciprocity and sociometri...
journal_title:Addictive behaviors
pub_type: 杂志文章
doi:10.1016/j.addbeh.2004.09.012
更新日期:2005-06-01 00:00:00
abstract::Smoking habits are continuously changing in the population. Cessation of smoking is not only often difficult but may lead to undesired consequences, esp. to weight gain. A random sample of 2283 persons with mild hypertension was followed up for 5 years in Eastern Finland and examined at the community-based cardiovascu...
journal_title:Addictive behaviors
pub_type: 杂志文章
doi:10.1016/0306-4603(86)90002-x
更新日期:1986-01-01 00:00:00
abstract:BACKGROUND:While parental supervision has been demonstrated to influence adolescent alcohol involvement, lack of a threshold defining inadequate supervision and little study of DSM defined alcohol use disorders (AUDs) have limited clinical applications. Utilizing a four-item supervision scale, this study identified ado...
journal_title:Addictive behaviors
pub_type: 杂志文章
doi:10.1016/j.addbeh.2005.07.017
更新日期:2005-10-01 00:00:00
abstract:OBJECTIVE:To examine the association between onset of substance use and risk factors related to suicide. METHOD:1252 adolescents in two urban school districts completed surveys as part of a large, randomized controlled prevention effectiveness trial. Risk factors measured included depressive symptoms, suicide ideation...
journal_title:Addictive behaviors
pub_type: 杂志文章
doi:10.1016/j.addbeh.2006.11.017
更新日期:2007-08-01 00:00:00
abstract::Currently our definitions of treatment success for obesity and eating disorders are too simplistic and narrow in scope. More varied treatment outcome targets include body-related measures, medical health variables, exercise and eating habits, psychological health factors, body image, and quality of life measures. A ne...
journal_title:Addictive behaviors
pub_type: 杂志文章,评审
doi:10.1016/0306-4603(96)00033-0
更新日期:1996-11-01 00:00:00
abstract:PURPOSE:Adolescents with substance use (SU) problems have high rates of tobacco use, yet SU treatment has historically ignored treatment for tobacco use. Barriers to such efforts include the belief that tobacco cessation could compromise other SU abstinence. This study examines self-initiated tobacco cessation and 12-m...
journal_title:Addictive behaviors
pub_type: 杂志文章
doi:10.1016/j.addbeh.2008.10.002
更新日期:2009-02-01 00:00:00
abstract::Treatment studies provide minimal support for nicotine replacement therapy (NRT) with youth; however, survey studies suggest that adolescents use NRT, and may engage in inappropriate use. The current study sought to examine patterns of NRT use and risk factors for use to further aid smoking cessation efforts including...
journal_title:Addictive behaviors
pub_type: 杂志文章
doi:10.1016/j.addbeh.2009.09.024
更新日期:2010-02-01 00:00:00
abstract::The effect of an appointment-keeping intervention on attendance at aftercare was examined for 50 male participants in an inpatient alcohol treatment program. Subjects received either a calendar prompt and home-based attendance contract intervention (Experimental group, N = 25) or standard aftercare treatment arrangeme...
journal_title:Addictive behaviors
pub_type: 临床试验,杂志文章
doi:10.1016/0306-4603(84)90010-8
更新日期:1984-01-01 00:00:00
abstract:BACKGROUND:Recently, the concept of addiction has expanded to include many types of problematic repetitive behaviors beyond those related to substance misuse. This trend may have implications for the way that lay people think about addictions and about people struggling with addictive disorders. The aim of this study w...
journal_title:Addictive behaviors
pub_type: 杂志文章
doi:10.1016/j.addbeh.2014.10.025
更新日期:2015-03-01 00:00:00
abstract:AIMS:This study examined the association between peer drug use and adolescent polysubstance use, and investigated if this association was moderated by parenting and/or school factors. METHODS:The sample consisted of 9966 participants (mean age=14.3; 49.34% males) randomly selected from secondary schools in Victoria, A...
journal_title:Addictive behaviors
pub_type: 杂志文章
doi:10.1016/j.addbeh.2016.08.004
更新日期:2017-01-01 00:00:00
abstract::Brief motivational interventions (BMIs) have been found to be efficacious for reducing alcohol use and consequences among college student drinkers. Despite the putative emphasis on motivation, surprisingly little is known about the role of motivation in BMI-facilitated changes. Using data from three published randomiz...
journal_title:Addictive behaviors
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.addbeh.2008.10.010
更新日期:2009-02-01 00:00:00
abstract::Demographic factors, characteristics of military service, PTSD, and depression were examined as predictors of alcohol misuse in Iraq and Afghanistan War Veterans (N=287) presenting for post-deployment Veteran Affairs (VA) health care. Results indicated that alcohol misuse was more common among younger male Veterans wh...
journal_title:Addictive behaviors
pub_type: 杂志文章
doi:10.1016/j.addbeh.2010.03.023
更新日期:2010-09-01 00:00:00
abstract::The present study sought to determine whether the high relapse rates observed among subjects in fixed length behavioral-based weight loss programs would be lowered if subjects were allowed to continue in treatment until they had reached their desired weights. Five hundred seventeen (517) clients at a commercial weight...
journal_title:Addictive behaviors
pub_type: 杂志文章
doi:10.1016/0306-4603(92)90007-i
更新日期:1992-09-01 00:00:00
abstract::The aim of the study was to examine psychometric properties of the PUN screening test concerning illicit drug problem use by adolescents. The criterion standard for the test's validity was a diagnostic interview conducted by trained specialists. Respondents were reached by snowball sampling in 58 randomly chosen Polis...
journal_title:Addictive behaviors
pub_type: 杂志文章
doi:10.1016/j.addbeh.2006.06.004
更新日期:2007-03-01 00:00:00
abstract::Despite the advent of improved pharmacological treatments to alleviate substance-related desires, psychological approaches will continue to be required. However, the current psychological treatment that most specifically focuses on desires and their management--cue exposure (CE)--has not lived up to its original promi...
journal_title:Addictive behaviors
pub_type: 杂志文章
doi:10.1016/j.addbeh.2004.06.009
更新日期:2004-09-01 00:00:00
abstract::This study was designed to uncover the fundamental psychological taste dimensions underlying people's ability to discriminate among commercial cigarettes, determine the roles that nicotine, tar, and carbon monoxide play in such taste dimensions, determine whether subjects can distinguish among cigarettes in general, a...
journal_title:Addictive behaviors
pub_type: 临床试验,杂志文章
doi:10.1016/0306-4603(86)90019-5
更新日期:1986-01-01 00:00:00
abstract:BACKGROUND:Substance use disorders (SUDs) and Post Traumatic Stress Disorder (PTSD) frequently co-occur among Veterans and are associated with poor treatment outcomes. Historically, treatments for SUDs and PTSD have been delivered sequentially and independently. More recently, however, integrated treatments have shown ...
journal_title:Addictive behaviors
pub_type: 杂志文章
doi:10.1016/j.addbeh.2013.09.017
更新日期:2014-02-01 00:00:00