Abstract：
:Adrenocortical carcinoma is a rare tumour with high malignancy and poor prognosis. This tumour is rarely diagnosed in the reproductive age. Complete surgical resection is the only curative treatment for adrenal cancer in all stages. After surgery adjuvant chemotherapy is required. Mitotane is the most important drug in adrenal cancer chemotherapy. Mitotane's mode of action is not entirely explained. Animal studies have shown that the substance exerts a direct cytotoxic effect on the cells of the adrenal cortex. This activity is selective, progressive and affects only the zona reticularis and fasciculata of the adrenal cortex. Mitotane inhibits cortisol synthesis by disrupting the chain of cholesterol. It has been suggested, that mitotane also affects the peripheral metabolism of steroids, especially of transcortin (CBG). This results in an increase of CBG blood concentration and a reduction of the amount of free hormones.
journal_name
Ginekol Poljournal_title
Ginekologia polskaauthors
Szkodziak PR,Czuczwar P,Woźniak S,Szkodziak F,Paszkowski Tdoi
10.5603/GP.a2017.0104subject
Has Abstractpub_date
2017-01-01 00:00:00pages
576-577issue
10eissn
0017-0011issn
2543-6767pii
VM/OJS/J/54006journal_volume
88pub_type
杂志文章abstract：OBJECTIVES:The aim of this study was to evaluate the safety, feasibility, and effectiveness of transvaginal myomectomy surgery. MATERIAL AND METHODS:We conducted a retrospective study in Shengjing Hospital of China Medical University. In all, 138 patients underwent transvaginal myomectomy from March 2009 to March 2019...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：10.5603/GP.2019.0106
更新日期：2019-01-01 00:00:00
abstract：OBJECTIVES:Real influence of urinary incontinence symptoms and adopted modes of treatment on patient's quality of life is not known. DESIGN:Assessment of influence of operative SUI treatment with the use of IVS tape on patient's quality of life. MATERIAL AND METHODS:Prospective study was conducted among 57 patients w...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2007-05-01 00:00:00
abstract：:Seventh caesarean section in the same pregnant woman was described. Pregnancy was terminated in 36 week of gestation cause of preterm uterine activity, after getting pulmonary maturation and estimating ultrasound fetal weight over three kilograms. The caesarean section and postoperative period were uncomplicated. Ther...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2001-12-01 00:00:00
abstract：:The authors discuss the foundations of mathematical analysis of fetal electrocardiograms, with particular reference to the obtaining of ECG signal by indirect method, and signal processing. ...
journal_title：Ginekologia polska
pub_type： 杂志文章,评审
doi：
更新日期：1989-06-01 00:00:00
abstract：:Polycystic ovary syndrome (PCOS) is the most common endocrinopathy in women of reproductive age. It is manifested by hyperandrogenism, polycystic ovaries on ultrasound, oligomenorrhoea and anovulation. PCOS patients are more vulnerable to metabolic disorders: insulin resistance, obesity endothelium dysfunction, athero...
journal_title：Ginekologia polska
pub_type： 杂志文章,评审
doi：
更新日期：2015-04-01 00:00:00
abstract：:Osteoporosis is a great problem in postmenopausal women. It begins 4--5 years after a last period and appears in clinical form in about 25-44% women. Basic irregularity is osteopenia as a result of bone resorption superiority. Many observations lead to conclusion that postmenopausal osteoporosis follows estrogens defi...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1995-01-01 00:00:00
abstract：:The course of actinomycetic infections in two females with IUD is presented. Both patients needed surgery. Literature review taking into a special consideration laboratory diagnosis has been performed. Infection caused by other than Actinomyces israelii species was observed. ...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2001-07-01 00:00:00
abstract：:Maldevelopment of the müllerian ducts occurs in a variety of forms, and each anomaly is distinctive. Nevertheless, some generalizations can be made. A comprehensive preoperative evaluation of patients with suspected uterovaginal malformations is essential, but a clear understanding of the particular anomaly may not be...
journal_title：Ginekologia polska
pub_type： 杂志文章,评审
doi：
更新日期：2005-11-01 00:00:00
abstract：UNLABELLED:There are many methods of the growth restriction therapy, but the results are still not satisfactory. Actually, we are conducting a project which main conception is based on the use of the NO donor (L-arginine) in growth retardation therapy. This amino acid is an effective NO donor and has a vasodilating eff...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2004-12-01 00:00:00
abstract：:Worldwide screening for early detection of ovarian cancer in both, the general population and the group of women at high risk for ovarian cancer including BRCA genes mutations carriers, has proven to be ineffective. The recommended screening methods, including a pelvic examination, transvaginal ultrasound, and CA125 p...
journal_title：Ginekologia polska
pub_type： 杂志文章,评审
doi：10.17772/gp/1735
更新日期：2014-05-01 00:00:00
abstract：:Prognostic value of some clinical factors on the course of subsequent pregnancy in 117 women with unexplained recurrent spontaneous abortion undergoing immunization with paternal lymphocytes were evaluated in the study. The results allow to conclude that high efficiency of alloimmunization in preventing consecutive ab...
journal_title：Ginekologia polska
pub_type： 临床试验,杂志文章
doi：
更新日期：1997-04-01 00:00:00
abstract：:182 hysteroscopic operations with electroresectoscope use performed in Ist Department of Obstetrics and Gynaecology (Warsaw) between 1996-1999 were analyzed. Myomectomy was performed in 117 patients, resection of uterine septum in 25 and deliberation of intrauterine adhesions in 40 patients. Abnormal bleeding and infe...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2000-09-01 00:00:00
abstract：:Diagnostic microlaparoscopy was performed on 30 patients aged 17-41. Indications++ for these procedures were: sterility (17), tumor of the ovary (5), endometriosis (3), uterine myoma (2), pelvic pain syndrome++ (1), carcinoma of the ovary--second look procedures (1), operative hysteroscopy (1). During these procedures...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1999-08-01 00:00:00
abstract：:Authors described gestational trophoblastic disease in 15 year old girl with concomitant disseminated intravascular clotting. beta HCG was higher that 100,000 mIU/ml. Serum beta HCG level decreased after evacuation of a molar pregnancy. Physiological level was achieved 3 months later. Theco-lutein cyst grew smaller in...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1999-05-01 00:00:00
abstract：:Concentrations of two acute phase proteins: alpha 2-macroglobulin (alpha 2M) and transferrin (Tf) as well as glycosylation profiles of alpha 2M and Tf were studied in sera samples from 13 patients suffering from ovarian cancer. In the observed group of patients with ovarian cancer in whom the progression of disease wa...
journal_title：Ginekologia polska
pub_type： 临床试验,杂志文章
doi：
更新日期：2001-01-01 00:00:00
abstract：:120 adolescent girl suffered from acyclic pelvic pain and dysmenorrhoe (algomenorrhoee) was presented. They were treated with nonsteroidal anti-inflammatory drugs (NSAIDs) and oral contraceptive pills (OCPs) and underwent a laparoscopy to determine the etiology of pelvic pain. Endometriosis was classified according to...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1999-05-01 00:00:00
abstract：OBJECTIVES:Paternal lymphocytes immunization has been proposed for several years as an efficient treatment for unexplained Recurrent Spontaneous Abortion (RSA), however precise mechanism that underline the benefits of this immunotherapy is still unclear. DESIGN:The aim was to study the influence of paternal lymphocyte...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2001-12-01 00:00:00
abstract：OBJECTIVES:Kujawsko-pomorskie province is a region with high morbidity and death-rate from uterine cervix cancer. One of the methods of improve this situation is to perform prophylactic physical examinations to find the least advanced stages as possible. DESIGN:The aim of the study was to estimate the results of proph...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2005-09-01 00:00:00
abstract：:There are suggestions that free radicals are involved in some dysfunctions observed in preeclampsia. In this study we have examined the effect of Trolox (water soluble vitamin E analog) on placental lipid peroxidation. Placentas from 20 normal and 20 preeclamptic woman were used in this study. Lipoperoxidative process...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1998-12-01 00:00:00
abstract：:The activity of N-acetyltransferase (NAT) and catalase was measured in the tissues of placenta, full venous blood and full umbilical cord blood in 141 complicated pregnancies. The control group consisted of 34 physiological pregnancies. The enzymes activity was marked by use of biochemical methods. It has been shown t...
journal_title：Ginekologia polska
pub_type： 临床试验,杂志文章
doi：
更新日期：1996-06-01 00:00:00
abstract：:The stromal Leydig cell tumour (SLCT), a very rare, benign neoplasm was described in 75-year old woman. The patient presented the typical signs of virilisation (hirsutism, masculine alopecia, moderate clitoris enlargement, deep voice) as well as hypertension and insulin independent type of diabetes mellitus (IIDM). Ad...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2001-10-01 00:00:00
abstract：UNLABELLED:Chlamydia trachomatis (CT) infection during pregnancy might be the reason of an increased risk of preterm delivery and premature rupture of membranes. CT could also be responsible for the presence of intrauterine growth restriction, chorionamnionitis and post partum endometritis. It is the most common sexual...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2007-10-01 00:00:00
abstract：UNLABELLED:The effective functions of human peripheral blood neutrophil are modulated by regulatory molecules depending on receptor agonists and adhesion molecules. OBJECTIVES:Evaluation of percentage of neutrophil adhesion molecules in pregnancy of diabetic mothers as well as their expression on peripheral blood neut...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2000-06-01 00:00:00
abstract：:127 pregnant patients between 20 and 37 week of gestation were studied. Cervical estimation was done by using transvaginal ultrasonography. An accurate estimation was possible in all investigation patients. Statistically significant distinctions in uterine cervical length during pregnancy progress were noticed (p < 0....
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1994-08-01 00:00:00
abstract：OBJECTIVES:The aim of the study was to analyze the course of labor of grand multiparas (4 deliveries and more) in comparison to multiparas (2 or 3 deliveries). MATERIALS AND METHODS:A group of 400 grand multiparas were included in the study and compared with a group of 393 multiparas. All the deliveries took place in ...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2006-12-01 00:00:00
abstract：:We investigated the vitamin D receptor (VDR) and the estrogen receptor (ER) genes polymorphism in studied groups was similar, however the allelic combination BBPPxx was associated with low bone mineral mass. There is a need to perform genetic test in the cohort of polish women endangered by osteoporosis. ...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2000-08-01 00:00:00
abstract：OBJECTIVES:The aim of the study was to determine whether anhydramnios affected the duration of medical abortion in cases with various indications as compared to cases with normal amniotic fluid volume. MATERIAL AND METHODS:Patients who were admitted to our clinic because of medical abortion between January 2010-Decemb...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：10.5603/GP.2016.0058
更新日期：2016-01-01 00:00:00
abstract：:Emergency cerclage was performed on 27 years old patient with membrane prolapse in 21 weeks' gestation. Ultrasonographically guided amniocentesis was performed intraoperatively in order to decrease intraamniotic pressure. Aggressive prophylactic management (wide spectrum antibiotics and tocolysis-nifedipine) resulted ...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2001-12-01 00:00:00
abstract：UNLABELLED:Preeclampsia is one of the most frequent and dangerous complications of a pregnancy. In preeclamptic pregnancies the spiral arteries are not modified properly. Disturbed blood flow finally leads to hypoxia which is responsible for the dysfunction of the endothelium. Endothelial growth factor (VEGF) and place...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2007-11-01 00:00:00
abstract：DESIGN:The aim of our study was a currently clinical analysis of menarche. MATERIALS AND METHODS:The mean age of menarche was investigated in 4497 girls between 1975-1997 69 girls were examined throughly in the course of menarche. Age at menarche, body weight, height, body mass index (BMI), some of the hormones and ul...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1999-05-01 00:00:00
