Differential effects on membrane permeability and viability of human keratinocyte cells undergoing very low intensity megasonic fields.

abstract：:We conduct textual analysis of a sample of more than 200,000 papers written on HIV/AIDS during the past three decades. Using the Latent Dirichlet Allocation method, we disentangle studies that address behavioral and social aspects from other studies and measure the trends of different topics as related to HIV/AIDS. We...

journal_title：Scientific reports

authors： Baghaei Lakeh A,Ghaffarzadegan N

更新日期：2017-06-23 00:00:00

abstract：:In the eyeblink conditioning paradigm, cerebellar Purkinje cells learn to respond to the conditional stimulus with an adaptively timed pause in its spontaneous firing. Evidence suggests that the pause is elicited by glutamate released from parallel fibers and acting on metabotropic receptors (mGluR7) which initiates a...

journal_title：Scientific reports

authors： Johansson F,Hesslow G

更新日期：2020-09-24 00:00:00

abstract：:Myeloid-derived suppressor cells (MDSCs) are immune cells that exert immunosuppression within the tumor, protecting cancer cells from the host's immune system and/or exogenous immunotherapies. While current research has been mostly focused in countering MDSC-driven immunosuppression, little is known about the mechanis...

journal_title：Scientific reports

authors： Duarte-Sanmiguel S,Shukla V,Benner B,Moore J,Lemmerman L,Lawrence W,Panic A,Wang S,Idzkowski N,Guio-Vega G,Higuita-Castro N,Ghadiali S,Carson WE,Gallego-Perez D

更新日期：2020-01-27 00:00:00

abstract：:In the fifty years since the postulation of Moore's Law, the increasing energy consumption in silicon electronics has motivated research into emerging devices. An attractive research direction is processing information via the phase of spin waves within magnonic-logic circuits, which function without charge transport ...

journal_title：Scientific reports

authors： Kanazawa N,Goto T,Sekiguchi K,Granovsky AB,Ross CA,Takagi H,Nakamura Y,Uchida H,Inoue M

更新日期：2017-08-11 00:00:00

abstract：:We established in vivo and in vitro models to investigate the role of αB-Crystallin (CryAB) and assess the ability of aspirin (ASA) to protect the myocardium during prolonged heat stress. Thirty-day-old chickens were divided into three groups (n = 90): heat stress (HS, 40±1 °C); ASA(-)HS(+), 1 mg/kg ASA orally 2 h bef...

journal_title：Scientific reports

authors： Tang S,Yin B,Song E,Chen H,Cheng Y,Zhang X,Bao E,Hartung J

更新日期：2016-11-18 00:00:00

abstract：:Magnesium-based thermoelectric materials (Mg2X, X = Si, Ge, Sn) have received considerable attention due to their availability, low toxicity, and reasonably good thermoelectric performance. The synthesis of these materials with high purity is challenging, however, due to the reactive nature and high vapour pressure of...

journal_title：Scientific reports

authors： Santos R,Nancarrow M,Dou SX,Aminorroaya Yamini S

更新日期：2017-06-21 00:00:00

abstract：:Why humans cooperate in large groups and with non-kin remains a puzzle for researchers across the natural and social sciences. Investigating whether cooperation is sexually selected could contribute to an understanding of the evolution of human cooperation. Competition for access to mates could indeed select for coope...

journal_title：Scientific reports

authors： Tognetti A,Dubois D,Faurie C,Willinger M

更新日期：2016-07-14 00:00:00

abstract：:Whole genome sequencing (WGS) can elucidate Mycobacterium tuberculosis (Mtb) transmission patterns but more data is needed to guide its use in high-burden settings. In a household-based TB transmissibility study in Peru, we identified a large MIRU-VNTR Mtb cluster (148 isolates) with a range of resistance phenotypes, ...

journal_title：Scientific reports

authors： Dixit A,Freschi L,Vargas R,Calderon R,Sacchettini J,Drobniewski F,Galea JT,Contreras C,Yataco R,Zhang Z,Lecca L,Kolokotronis SO,Mathema B,Farhat MR

更新日期：2019-04-03 00:00:00

abstract：:After HSP70 binds to the J domain of the substrate and co-chaperone protein, ATP is hydrolyzed to ADP, and the nucleotide exchange factors (NEFs) promote the release of ADP. Under physiological conditions, the nucleotide exchange step is the rate-limiting step, which is accelerated by NEFs. In this study, the promoter...

journal_title：Scientific reports

authors： Chen S,Qiu G

更新日期：2020-10-14 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Guo Z,Liu H,Ni H,Wang X,Su M,Guo W,Wang K,Jiang T,Qian Y

更新日期：2020-05-20 00:00:00

abstract：:Bacterial artificial chromosomes (BACs) offer a means of manipulating gene expression and tagging gene products in the mammalian genome without the need to alter endogenous gene structure and risk deleterious phenotypic consequences. However, for a BAC clone to be useful for such purposes it must be shown to contain a...

journal_title：Scientific reports

authors： Warr N,May J,Teboul L,Suzuki T,Asami M,Perry ACF,Wells S,Greenfield A

更新日期：2018-11-23 00:00:00

abstract：:Breast cancer in young women is typically with higher proportion of adverse pathological features. Breast cancer with BRCA1 mutation is often early-onset, and is usually associated with triple negative phenotpe. In this study, we aim to analyze the clinicopathological characteristics and prognosis in young breast canc...

journal_title：Scientific reports

authors： Wei JT,Huang WH,Du CW,Qiu SQ,Wei XL,Liu J,Zhang GJ

更新日期：2014-06-19 00:00:00

abstract：:Atrial fibrillation (AF) is known to cause adverse remodeling of left atrium (LA). Radiofrequency catheter ablation (RFCA) of AF is associated with decrease in LA volume. However, the impact of RFCA on left atrial appendage (LAA) volume and hemodynamic function is not fully understood. We analyzed 123 patients who und...

journal_title：Scientific reports

authors： Kim YG,Shim J,Oh SK,Park HS,Lee KN,Hwang SH,Choi JI,Kim YH

更新日期：2018-05-18 00:00:00

abstract：:Common genetic risk variants for colorectal cancer (CRC) have been identified at approximately 40 loci by genome-wide association studies (GWAS). We investigated the association of these risk variants by age at onset of CRC using case-only and case-control analysis. A total of 1,962 CRC cases and 2,668 controls from t...

journal_title：Scientific reports

authors： Song N,Shin A,Park JW,Kim J,Oh JH

更新日期：2017-01-13 00:00:00

abstract：:Tumor-associated macrophages (TAMs) play critical roles in promoting tumor progression and invasion. However, the molecular mechanisms underlying TAM regulation remain to be further investigated and may make significant contributions to cancer treatment. Mammalian microRNAs (miRNAs) have recently been identified as im...

journal_title：Scientific reports

authors： Li Y,Zhao L,Shi B,Ma S,Xu Z,Ge Y,Liu Y,Zheng D,Shi J

更新日期：2015-12-22 00:00:00

abstract：:The pearl oyster is one of the rare animal models that support two distinct genomes, through the surgical graft process operated for culture pearl production. This grafted organism is assimilated to a chimera whose physiological functioning remains poorly known. The question of the energy expenditure comparison betwee...

journal_title：Scientific reports

authors： Le Moullac G,Soyez C,Ky CL

更新日期：2018-05-14 00:00:00

abstract：:The expression of aminoglycoside-modifying enzymes represents a survival strategy of antibiotic-resistant bacteria. Aminoglycoside 2'-N-acetyltransferase [AAC(2')] neutralizes aminoglycoside drugs by acetylation of their 2' amino groups in an acetyl coenzyme A (CoA)-dependent manner. To understand the structural featu...

journal_title：Scientific reports

authors： Jeong CS,Hwang J,Do H,Cha SS,Oh TJ,Kim HJ,Park HH,Lee JH

更新日期：2020-12-09 00:00:00

abstract：:Acid-sensing ion channels (ASICs) belong to the degenerin/epithelial sodium channel protein family that form mechanosensitive ion channels. Evidence as to whether or not ASICs activity is directly modulated by mechanical force is lacking. Human ASICs (hASIC1V3, hASIC2a and hASIC3a) were heterologously expressed as hom...

journal_title：Scientific reports

authors： Barth D,Fronius M

更新日期：2019-05-01 00:00:00

abstract：:We previously demonstrated that ABCD4 does not localize to peroxisomes but rather, the endoplasmic reticulum (ER), because it lacks the NH2-terminal hydrophilic region required for peroxisomal targeting. It was recently reported that mutations in ABCD4 result in a failure to release vitamin B12 from lysosomes. A simil...

journal_title：Scientific reports

authors： Kawaguchi K,Okamoto T,Morita M,Imanaka T

更新日期：2016-07-26 00:00:00

abstract：:Sterility mosaic disease (SMD) is one of the serious production constraints that may lead to complete yield loss in pigeonpea. Three mapping populations including two recombinant inbred lines and one F2, were used for phenotyping for SMD resistance at two locations in three different years. Genotyping-by-sequencing ap...

journal_title：Scientific reports

authors： Saxena RK,Kale SM,Kumar V,Parupali S,Joshi S,Singh V,Garg V,Das RR,Sharma M,Yamini KN,Ghanta A,Rathore A,Sameerkumar CV,Saxena KB,Varshney RK

更新日期：2017-05-12 00:00:00

abstract：:Practical application of superhydrophobic surfaces is limited by the fragility of nanoscale asperities. Combining chemical etching and anodization, microscale pits and nanoscale pores, instead of the micro and nano protrusions on traditional superhydrophobic surfaces mimicking Lutos leaves, were fabricated on commerci...

journal_title：Scientific reports

authors： Wang G,Liu S,Wei S,Liu Y,Lian J,Jiang Q

更新日期：2016-02-08 00:00:00

abstract：:In arthropods, retinoid X receptor (RXR) is a highly conserved nuclear hormone receptor. By forming a heterodimeric complex with the ecdysone receptor (EcR), RXR is known to be vital importance for various physiological processes. However, in comparison to EcR, the RXR signaling pathway and its roles in crustacean rep...

journal_title：Scientific reports

authors： Gong J,Huang C,Shu L,Bao C,Huang H,Ye H,Zeng C,Li S

更新日期：2016-03-24 00:00:00

abstract：:Male infertility due to spermatogenesis defects affects millions of men worldwide. However, the genetic etiology of the vast majority remains unclear. Here we describe three men with primary infertility due to multiple morphological abnormalities of the sperm flagella (MMAF) from two unrelated Han Chinese families. We...

journal_title：Scientific reports

authors： Tu C,Nie H,Meng L,Yuan S,He W,Luo A,Li H,Li W,Du J,Lu G,Lin G,Tan YQ

更新日期：2019-11-01 00:00:00

abstract：:To ensure the reliability of the planned multi-center clinical trial, we assessed the consistence and comparability of the quantitative parameters of the eight PET/CT units that will be used in this trial. PET/CT images were scanned using a PET NEMA image quality phantom (Biodex) on the eight units of Discovery PET/CT...

journal_title：Scientific reports

authors： Zhu Y,Geng C,Huang J,Liu J,Wu N,Xin J,Xu H,Yu L,Geng J

更新日期：2018-06-13 00:00:00

abstract：:To determine the incidence of acute cardiac injury (ACI), the factors associated with ACI and the in-hospital mortality in patients with COVID-19, especially in severe patients. All consecutive in-patients with laboratory-confirmed COVID-19 from Tongji Hospital in Wuhan during February 1 and March 29, 2020 were includ...

journal_title：Scientific reports

authors： He X,Wang L,Wang H,Xie Y,Yu Y,Sun J,Yan J,Du Y,Shen Y,Zeng H

更新日期：2020-11-24 00:00:00

abstract：:Sphingopyxis granuli strain TFA is an α-proteobacterium that belongs to the sphingomonads, a group of bacteria well-known for its degradative capabilities and oligotrophic metabolism. Strain TFA is the only bacterium in which the mineralisation of the aromatic pollutant tetralin has been completely characterized at bi...

journal_title：Scientific reports

authors： García-Romero I,Nogales J,Díaz E,Santero E,Floriano B

更新日期：2020-05-26 00:00:00

abstract：:In yeast, the pol3-01,L612M double mutant allele, which causes defects in DNA polymerase delta (Pol δ) proofreading (pol3-01) and nucleotide selectivity (pol3-L612M), confers an "ultramutator" phenotype that rapidly drives extinction of haploid and diploid MMR-proficient cells. Here, we investigate antimutator mutatio...

journal_title：Scientific reports

authors： Dennis DG,McKay-Fleisch J,Eitzen K,Dowsett I,Kennedy SR,Herr AJ

更新日期：2017-04-18 00:00:00

abstract：:The goal of this study was to evaluate the risk of developing acute myocardial infarction (AMI) following retinal vein occlusion (RVO). A retrospective cohort study was performed from the National Health Insurance Service and comprised 1,025,340 random subjects who were followed from 2002 to 2013. Patients with RVO in...

journal_title：Scientific reports

authors： Rim TH,Han JS,Oh J,Kim DW,Kang SM,Chung EJ

更新日期：2016-02-29 00:00:00

abstract：:Protocadherin 19 (Pcdh19) is an X-linked gene belonging to the protocadherin superfamily, whose members are predominantly expressed in the central nervous system and have been implicated in cell-cell adhesion, axon guidance and dendrite self-avoidance. Heterozygous loss-of-function mutations in humans result in the ch...

journal_title：Scientific reports

authors： Pederick DT,Homan CC,Jaehne EJ,Piltz SG,Haines BP,Baune BT,Jolly LA,Hughes JN,Gecz J,Thomas PQ

更新日期：2016-05-31 00:00:00

abstract：:Environmental pollution by emerging contaminants, e.g. pharmaceuticals, has become a matter of widespread concern in recent years. We investigated the membrane transport of diclofenac and its toxic effects on gene expression and the development of zebrafish embryos. The association of diclofenac with the embryos confo...

journal_title：Scientific reports

authors： Chen JB,Gao HW,Zhang YL,Zhang Y,Zhou XF,Li CQ,Gao HP

更新日期：2014-05-02 00:00:00