Abstract：
:We investigated concentrations and roles of insulin-like growth factor 1 (IGF-1) and its binding protein (IGF1BP-3), growth hormone (GH), insulin, and markers of insulin resistance and inflammation in acute myocardial infarction (AMI). We aimed to assess any possible association between serum GH/IGF-1 axis following AMI and short-term survival rates. A follow up study was performed in 2010. Study group consisted of 75 patients with Killip I and II class AMI. There were 30 control subjects. Blood samples were obtained within 24 hours of admission and analyzed for the aforementioned hormones. Patients were followed-up during 6 months for new cardiac events. Median GH was higher in AMI (0.96; range 0.6-2.4) than in controls (0.26; p<0.001). IGF-1 was significantly lower in AMI (123 vs. 132; p<0.05), and so was the IGF-1/GH ratio (p<0.001) and IGF1BP-3. Insulin was higher in study group, but without statistical significance. However, we found significant between-group differences in other markers of insulin resistance (HbA1c, glycemia, HOMA-IR) and inflammation. Simple linear correlation showed positive correlation between GH and C-reactive protein. All patients with new cardiac events had IGF-1 below median and lower left ventricular ejection fraction. In conclusion, IGF-1 may affect outcome of AMI. GH resistance might be a result of inflammatory/immune response and therefore it could be a useful prognostic marker.
journal_name
Acta Clin Croatjournal_title
Acta clinica Croaticaauthors
Dizdarević-Hudić L,Kusljugić Z,Baraković F,Hajder M,Hudić Idoi
10.20471/acc.2016.55.03.01subject
Has Abstractpub_date
2016-09-01 00:00:00pages
345-353issue
3eissn
0353-9466issn
1333-9451journal_volume
55pub_type
杂志文章abstract：:Two clinical forms of the "white spot" syndrome in patients with posterior uveitis in definitive and presumable ocular sarcoidosis were analyzed. Group 1 was characterized by periphlebitis and discrete white spots around the vein of the retina, so-called "candle-wax", whereas group 2 showed yellow-orange solitary nodu...
journal_title：Acta clinica Croatica
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doi：
更新日期：2012-06-01 00:00:00
abstract：:The goal of this study was to evaluate the association between self-perceived social support and chronic combat-related posttraumatic stress disorder (PTSD). The study included 262 male war veterans suffering from chronic PTSD. Their diagnosis was confirmed according to DSM-IV-TR. They were given self-reported measure...
journal_title：Acta clinica Croatica
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doi：
更新日期：2011-06-01 00:00:00
abstract：:Triple-negative breast cancer (TNBC) occurs in around one-sixth of all breast cancer (BC) patients, with the most aggressive behavior and worst prognosis of all BC subtypes. It is a heterogeneous disease, with specific molecular characteristics and natural dynamics of early recurrence and fast progression. Due to the ...
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journal_title：Acta clinica Croatica
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更新日期：2011-03-01 00:00:00
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journal_title：Acta clinica Croatica
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更新日期：2011-03-01 00:00:00
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journal_title：Acta clinica Croatica
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doi：
更新日期：2011-09-01 00:00:00
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journal_title：Acta clinica Croatica
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journal_title：Acta clinica Croatica
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doi：
更新日期：2011-09-01 00:00:00
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journal_title：Acta clinica Croatica
pub_type： 杂志文章,评审
doi：
更新日期：2014-09-01 00:00:00
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journal_title：Acta clinica Croatica
pub_type： 杂志文章
doi：10.20471/acc.2019.58.02.07
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journal_title：Acta clinica Croatica
pub_type： 杂志文章,随机对照试验
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更新日期：2017-06-01 00:00:00
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journal_title：Acta clinica Croatica
pub_type： 杂志文章
doi：
更新日期：2011-12-01 00:00:00
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journal_title：Acta clinica Croatica
pub_type： 杂志文章
doi：
更新日期：2010-12-01 00:00:00
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journal_title：Acta clinica Croatica
pub_type： 杂志文章
doi：
更新日期：2012-12-01 00:00:00
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journal_title：Acta clinica Croatica
pub_type： 杂志文章
doi：10.20471/acc.2017.56.01.15
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journal_title：Acta clinica Croatica
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journal_title：Acta clinica Croatica
pub_type： 杂志文章,评审
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journal_title：Acta clinica Croatica
pub_type： 杂志文章
doi：10.20471/acc.2016.55.02.08
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journal_title：Acta clinica Croatica
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doi：
更新日期：2013-03-01 00:00:00
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journal_title：Acta clinica Croatica
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更新日期：2008-12-01 00:00:00
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journal_title：Acta clinica Croatica
pub_type： 杂志文章
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journal_title：Acta clinica Croatica
pub_type： 杂志文章,评审
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journal_title：Acta clinica Croatica
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更新日期：2009-03-01 00:00:00
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journal_title：Acta clinica Croatica
pub_type： 杂志文章
doi：10.20471/acc.2016.55.03.24
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journal_title：Acta clinica Croatica
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doi：10.20471/acc.2019.58.04.22
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abstract：:- Mycological analysis is considered the gold standard in the diagnosis of very common fungal diseases of nails. The purpose of the article is to present the prevalence of onychomycosis obtained by using direct microscopic examination (DME) and cultivation on Sabouraud media without cycloheximide. The quantitative ret...
journal_title：Acta clinica Croatica
pub_type： 杂志文章
doi：10.20471/acc.2018.57.04.15
更新日期：2018-12-01 00:00:00
