Abstract：
:The aim was to determine the validity of the international normalized ratio (INR) and prothrombin time (PT) as a monitor for warfarin therapy in patients with lupus anticoagulants and recurrent thrombosis, and to investigate alternative approaches to monitoring warfarin therapy and new treatment options in these patients. A case is described of a 63-year-old female with antiphospholipid syndrome and recurrent venous thrombosis despite optimal adjusted warfarin therapy. In patients with lupus anticoagulants, the INRs obtained while receiving warfarin vary and often overestimate the extent of anticoagulation, while PT without receiving warfarin is often prolonged. In conclusion, lupus anticoagulants can influence PT and lead to INR that does not accurately reflect the true level of anticoagulation. Optimizing of (warfarin) oral anticoagulation therapy could be achieved by individual monitoring of anticoagulation effect with a test thatis insensitive to lupus anticoagulants (chromogenic factor X assay). Emerging oral anticoagulants, direct thrombin inhibitors and direct factor Xa inhibitors, such as dabigatran and rivaroxaban, with a predictable anticoagulant response and little potential for food or drug interactions, have been designed to be administered in fixed doses without coagulation monitoring and could be the treatment choice for these patients.
journal_name
Acta Clin Croatjournal_title
Acta clinica Croaticaauthors
Balaban M,Stanrić V,Rincić G,Ledinsky M,Grbac L,Stancić N,Tomasić Hsubject
Has Abstractpub_date
2010-12-01 00:00:00pages
469-77issue
4eissn
0353-9466issn
1333-9451journal_volume
49pub_type
杂志文章,评审abstract：:Despite decades of experience in tracheotomy, there still exists a controversy over its ideal timing. The aim of our study was to compare the impact of early and late percutaneous tracheotomy in terms of their ability to reduce mechanical ventilation duration and length of stay in Intensive Care Unit, as well as the f...
journal_title：Acta clinica Croatica
pub_type： 杂志文章
doi：
更新日期：2016-03-01 00:00:00
abstract：:Unicameral bone cysts (UBC) are benign bone tumor-like lesions. Mostly they are located in the metaphyseal-diaphyseal region of long bones in children and adolescents. The etiology of UBC is still unclear. There is no consensus about the protocol of UBC treatment. The aim of this study was to evaluate the effectivenes...
journal_title：Acta clinica Croatica
pub_type： 杂志文章
doi：10.20471/acc.2019.58.03.01
更新日期：2019-09-01 00:00:00
abstract：:Foreign body ingestion is a common problem in children, but magnet ingestion is relatively rare. However, when it occurs, it tends to have a high rate of complications. This is a case report of a 3-year-old child who swallowed multiple magnetic toys, subsequently developing jejunoileal perforation and volvulus. This c...
journal_title：Acta clinica Croatica
pub_type： 杂志文章
doi：
更新日期：2015-03-01 00:00:00
abstract：:We investigated concentrations and roles of insulin-like growth factor 1 (IGF-1) and its binding protein (IGF1BP-3), growth hormone (GH), insulin, and markers of insulin resistance and inflammation in acute myocardial infarction (AMI). We aimed to assess any possible association between serum GH/IGF-1 axis following A...
journal_title：Acta clinica Croatica
pub_type： 杂志文章
doi：10.20471/acc.2016.55.03.01
更新日期：2016-09-01 00:00:00
abstract：:The aim of this paper is to present epidemiological features of reported patients with invasive meningococcal disease in the Split-Dalmatia County in the period from January 1996 to December 2010. During the 15-year period (1996-2010), a total of 119 patients were reported to have invasive meningococcal disease, yield...
journal_title：Acta clinica Croatica
pub_type： 杂志文章
doi：
更新日期：2013-12-01 00:00:00
abstract：:The aim of this study was to evaluate the implementation of the 9th edition of the American College of Chest Physicians (ACCP9) guidelines for prevention of venous thromboembolism in nonsurgical patients in clinical practice in one university and one general Croatian hospital. A retrospective study was conducted at Za...
journal_title：Acta clinica Croatica
pub_type： 杂志文章
doi：10.20471/acc.2017.56.04.12
更新日期：2017-12-01 00:00:00
abstract：:Rabies is a zoonotic disease (a disease transmitted to humans from animals) that is caused by a virus. The disease affects domestic and wild animals, and is spread to people through close contact with infectious material, usually saliva, via bites or scratches. Rabies is present on all continents with the exception of...
journal_title：Acta clinica Croatica
pub_type： 杂志文章,评审
doi：10.20471/acc.2016.55.01.20
更新日期：2016-03-01 00:00:00
abstract：:The aim of the study was to identify differences in baseline characteristics and outcomes of men and women with acute ischemic stroke. Ischemic stroke was confirmed by CT scan or autopsy in patients admitted to the 2nd Department of Neurology, Institute of Psychiatry and Neurology in Warsaw, Poland from 1995 to 2007. ...
journal_title：Acta clinica Croatica
pub_type： 杂志文章
doi：
更新日期：2011-03-01 00:00:00
abstract：:Lumbar discectomy is the most common surgical treatment for intervertebral disc extrusion. Postoperative pain is a common clinical problem that greatly affects the length of hospitalization, functional status and patient quality of life. Th e aim of this study was to compare the postoperative analgesic effi cacy of pa...
journal_title：Acta clinica Croatica
pub_type： 杂志文章,随机对照试验
doi：10.20471/acc.2017.56.02.06
更新日期：2017-06-01 00:00:00
abstract：:Reverse shoulder prosthesis has become one of the most often used prosthetic implants in shoulder replacement surgery. It has a wide spectrum of indications, starting from comminuted humeral fractures and posttraumatic arthritis to arthritis caused by the rotator cuff loss. Its application at our hospital began in 200...
journal_title：Acta clinica Croatica
pub_type： 杂志文章
doi：
更新日期：2014-09-01 00:00:00
abstract：:Liposarcoma is one of the most common soft-tissue sarcomas in adults, but head and neck are rarely involved, especially regions of the larynx and hypopharynx. According to Enzinger and Weiss, liposarcoma can be divided into 5 subtypes: well-differentiated, myxoid, round cell, pleomorphic and dedifferentiated. We prese...
journal_title：Acta clinica Croatica
pub_type： 杂志文章,评审
doi：
更新日期：2014-09-01 00:00:00
abstract：:Previous findings on peripartum anxiety are inconsistent in respect to the prevalence and course of peripartum anxiety with comorbidity of depression. Our aim was threefold: (1) to examine the course of elevated anxiety during pregnancy, immediately after childbirth, and six weeks postpartum; (2) to establish comorbid...
journal_title：Acta clinica Croatica
pub_type： 杂志文章
doi：10.20471/acc.2017.56.04.05
更新日期：2018-03-01 00:00:00
abstract：:A rare clinical case of intraplacental intervillous hemorrhage (Kline's hemorrhage) is presented. After delivery of a premature newborn (810 g/35 cm) in 27th week of uncomplicated pregnancy, peripartum observation of the premature placenta (270 g, 16 x 16 x 1.8) suggested multiple intraplacental cavernae with semiflui...
journal_title：Acta clinica Croatica
pub_type： 杂志文章
doi：
更新日期：2011-09-01 00:00:00
abstract：:The aim was to assess whether standard automated perimetry (SAP) and frequency doubling technology (FDT) perimetry are able to detect the effect of diabetes mellitus (DM) on retinal function in DM patients in the early stage of disease and to analyze which method is more specific and sensitive. A randomized cross-sect...
journal_title：Acta clinica Croatica
pub_type： 杂志文章
doi：10.20471/acc.2020.59.01.02
更新日期：2020-03-01 00:00:00
abstract：:Angiogenesis is essential for the development, growth and progression of tumors. Although vascular endothelial growth factor (VEGF) is a well-known proangiogenic factor, its impact on lymphoma has not yet been fully clarified. The aim of this study was to evaluate VEGF-A -expression and microvessel density (MVD) in ag...
journal_title：Acta clinica Croatica
pub_type： 杂志文章
doi：10.20471/acc.2017.56.04.02
更新日期：2017-12-01 00:00:00
abstract：:Renal artery embolism is a disease that is easily missed due to its infrequent and nonspecific presentations. Although early diagnosis and optimal thrombolytic treatment can sometimes restore renal function, therapeutic guidelines have not yet been established. However, early anticoagulant therapy is beneficial and se...
journal_title：Acta clinica Croatica
pub_type： 杂志文章
doi：
更新日期：2014-06-01 00:00:00
abstract：:Peripheral facial weakness is a facial nerve damage that results in muscle weakness on one side of the face. It may be idiopathic (Bell's palsy) or may have a detectable cause. Almost 80% of peripheral facial weakness cases are primary and the rest of them are secondary. The most frequent causes of secondary periphera...
journal_title：Acta clinica Croatica
pub_type： 杂志文章,评审
doi：
更新日期：2013-06-01 00:00:00
abstract：:Chemical peels are growing in popularity with new agents, formulas and methods giving them greater reliability and safety. Although the operative procedure may seem relatively simple, proper knowledge and skills of the physician and education of the patient is crucial. It is very important for the physician to know ch...
journal_title：Acta clinica Croatica
pub_type： 杂志文章
doi：
更新日期：2010-12-01 00:00:00
abstract：:The aim of the study was to assess how children and adolescents experience hospitalization and separation from their parents, their home and daily activities, in order to improve the psychosocial quality of hospital stay. Emotions and experiences reported by hospitalized children and adolescents are presented and disc...
journal_title：Acta clinica Croatica
pub_type： 杂志文章
doi：
更新日期：2009-06-01 00:00:00
abstract：:Endocrinopathies are relatively rare causes of erectile dysfunction. Cases of hyperprolactinemia and pituitary adenomas have been previously reported. We present a clinical case of a 27-year-old male with suspected infertility and recent symptoms of erectile dysfunction. Additional radiological and endocrinologic work...
journal_title：Acta clinica Croatica
pub_type： 杂志文章
doi：10.20471/acc.2020.59.01.22
更新日期：2020-03-01 00:00:00
abstract：:The rate of periprosthetic femoral fractures following total hip replacement has been growing steadily in the last 20 years and ranges from 0.1% to 2.1%. These fractures are mostly related to older patients with the presence of chronic diseases and frequently poor bone quality. The treatment is surgically very complex...
journal_title：Acta clinica Croatica
pub_type： 杂志文章
doi：10.20471/acc.2017.56.03.21
更新日期：2017-09-01 00:00:00
abstract：:Bleaching agents have effect on chemical/physical and morphological structure of enamel and dentin that must be taken into account when this therapy is used. The aim of this in vitro study was to evaluate the effects of two bleaching agents containing a high concentration of hydrogen peroxide for professional use on h...
journal_title：Acta clinica Croatica
pub_type： 杂志文章
doi：
更新日期：2013-12-01 00:00:00
abstract：:The aim of this study was to investigate the correlation of immunohistochemical expression of nm23 gene in colorectal cancer cells with tumor stage according to Dukes, tumor differentiation, occurrence of distant metastases and patient survival. This retrospective study included 100 colorectal cancer patients who unde...
journal_title：Acta clinica Croatica
pub_type： 杂志文章
doi：
更新日期：2012-03-01 00:00:00
abstract：:The aim of this prospective study was to evaluate whether cytokine levels in nasal secretions may be clinical parameters of severity of nasal polyposis. Forty nasal polyp patients (20 asthmatic and 20 nonasthmatic) requiring surgical treatment were included. Nasal secretion samples were collected from nasal cavities o...
journal_title：Acta clinica Croatica
pub_type： 杂志文章
doi：
更新日期：2010-12-01 00:00:00
abstract：:Person-oriented medicine is characterized by a holistic approach in patient ma- nagement that embraces physical, psychological, social and spiritual aspects of health and dise- ase. It responds to the needs of patients and health care workers to form an effective therapeutic relationship based on trust, empathy, compa...
journal_title：Acta clinica Croatica
pub_type： 杂志文章,评审
doi：
更新日期：2014-12-01 00:00:00
abstract：:The aim was to evaluate sexual function of healthy women in Croatia and the possible impact of depression, anxiety, and sociodemographic factors. A total of 204 healthy women filled in a basic sociodemographic questionnaire, the Patient Health Questionnaire-9, Anxiety Disorder-7, and Female Sexual Function Index (FSFI...
journal_title：Acta clinica Croatica
pub_type： 杂志文章
doi：10.20471/acc.2019.58.04.12
更新日期：2019-12-01 00:00:00
abstract：:Botryoid cyst, a rare type of odontogenic cyst, is usually considered a multilocular variant of lateral periodontal cyst. It was first described in 1973, and up to the present less than a hundred cases have been reported in the literature. Botryoid cysts are characterized by a multilocular histologic finding and a hig...
journal_title：Acta clinica Croatica
pub_type： 杂志文章
doi：10.20471/acc.2016.55.03.24
更新日期：2016-09-01 00:00:00
abstract：:The aim of the study was to assess the influence of gap shape on biomechanical results in extra-articular distal humeral fracture: with contact on the posterior part (by anterior gap) and contact on ulnar column (by radial gap). The goal was to examine if and to what extent did displacements decrease in comparison wit...
journal_title：Acta clinica Croatica
pub_type： 杂志文章
doi：10.20471/acc.2016.55.03.05
更新日期：2016-09-01 00:00:00
abstract：:Improving organization and patient care quality in intensive care units is increasingly important as intensive care unit diagnostic and therapeutic procedures account for a growing proportion of hospital services. We identified the lack of comprehensive national and international registries available in the contempora...
journal_title：Acta clinica Croatica
pub_type： 杂志文章
doi：10.20471/acc.2020.59.02.06
更新日期：2020-06-01 00:00:00
abstract：:Multiply injured patients with severe chest trauma have different combinations of associated extra thoracic injuries making their treatment complex. Severe pain is a prominent symptom in a vast majority of severe chest injuries and causes deterioration of respiratory function. Epidural analgesia provides efficient pai...
journal_title：Acta clinica Croatica
pub_type： 杂志文章,评审
doi：10.20471/acc.2019.58.s1.18
更新日期：2019-06-01 00:00:00
