Abstract：
:Angiogenesis is essential for the development, growth and progression of tumors. Although vascular endothelial growth factor (VEGF) is a well-known proangiogenic factor, its impact on lymphoma has not yet been fully clarified. The aim of this study was to evaluate VEGF-A -expression and microvessel density (MVD) in aggressive lymphoma such as diffuse large B-cell lymphoma (DLBCL), in indolent lymphomas such as low-grade follicular lymphoma (FL), and in lymph node reactive follicular hyperplasia (FH). In 80 prospective and retrospective cases (30 DLBCL, 30 FL and 20 FH), CD31 was analyzed by immunohistochemical staining assessing density of blood vessels, as well as the total number of CD31 positive endothelial cells. The results were compared with relevant clinical data. MVD was 85% in FH, followed by 60% in DLBCL and 43% in low-grade FL. VEGF-A was significantly higher in DLBCL than in low-grade FL and FH. A statistically significant association of MVD and VEGF-A with the International Prognostic Index (IPI) was found in DLBCL. High MVD and VEGF-A expression was observed in DLBCL patients with high IPI, while there was no statistically significant association between MVD and VEGF-A with the Follicular Lymphoma International Prognostic Index in low-grade FL. Our results suggested an important relationship between angiogenesis and high-grade lymphoma.
journal_name
Acta Clin Croatjournal_title
Acta clinica Croaticaauthors
Shahini L,Gašparov S,Petruševska G,Manxhuka Kerliu S,Veselaj F,Kurshumliu F,Kavaja Fdoi
10.20471/acc.2017.56.04.02subject
Has Abstractpub_date
2017-12-01 00:00:00pages
588-593issue
4eissn
0353-9466issn
1333-9451journal_volume
56pub_type
杂志文章abstract：:Acute stroke is one of the leading causes of morbidity and mortality worldwide, and as the most important cause of morbidity and long-term disability imposes an enormous economic burden. Stroke units (SU) are an effective option to fight stroke. According to the European Stroke Organization, SU should provide coordina...
journal_title：Acta clinica Croatica
pub_type： 杂志文章
doi：
更新日期：2009-09-01 00:00:00
abstract：:Acute disseminated encephalomyelitis (ADEM) is an inflammatory demyelinating disease of the central nervous system that usually affects children and young adults. It most commonly has a monophasic course, although relapses are reported. Clinical presentation of the disease includes encephalopathy and multifocal neurol...
journal_title：Acta clinica Croatica
pub_type：
doi：10.20471/acc.2019.58.01.22
更新日期：2019-03-01 00:00:00
abstract：:Nurses distinguish continuous professional development intended for career improvement and personal development from continuous professional development intended for improvement of skills and knowledge. Too many requests are put in front of an individual unacceptably stretching it onto the life outside work. Students ...
journal_title：Acta clinica Croatica
pub_type： 杂志文章
doi：
更新日期：2013-03-01 00:00:00
abstract：:A case is presented of a 59-year-old male patient with a 5-year history of sarcoidosis. In the last half a year, deterioration of his intellectual abilities was noticed. Psychological testing detected a mild cognitive disorder. Laboratory diagnostics found a decreased level of testosterone and magnetic resonance imagi...
journal_title：Acta clinica Croatica
pub_type： 杂志文章
doi：
更新日期：2011-12-01 00:00:00
abstract：:Foreign body ingestion is a common problem in children, but magnet ingestion is relatively rare. However, when it occurs, it tends to have a high rate of complications. This is a case report of a 3-year-old child who swallowed multiple magnetic toys, subsequently developing jejunoileal perforation and volvulus. This c...
journal_title：Acta clinica Croatica
pub_type： 杂志文章
doi：
更新日期：2015-03-01 00:00:00
abstract：:Liposarcoma is one of the most common soft-tissue sarcomas in adults, but head and neck are rarely involved, especially regions of the larynx and hypopharynx. According to Enzinger and Weiss, liposarcoma can be divided into 5 subtypes: well-differentiated, myxoid, round cell, pleomorphic and dedifferentiated. We prese...
journal_title：Acta clinica Croatica
pub_type： 杂志文章,评审
doi：
更新日期：2014-09-01 00:00:00
abstract：:Epilepsy is the most common neurological complication in pregnancy. Women with epilepsy have a higher risk of complications in pregnancy. In Croatia, women with epilepsy are treated by neurologists at tertiary centers according to the place of residence. We prospectively followed-up pregnancies in women with epilepsy ...
journal_title：Acta clinica Croatica
pub_type： 杂志文章
doi：10.20471/acc.2016.55.04.02
更新日期：2016-12-01 00:00:00
abstract：:The finding of osteoarthritis of temporomandibular joint (TMJ) obtained by clinical diagnosis, i.e. manual functional analysis (MFA) and the finding obtained by magnetic resonance imaging (MRI) as the gold standard were compared in 30 patients (mean age 52.6) diagnosed with osteoarthritis, selected out of 140 consecut...
journal_title：Acta clinica Croatica
pub_type： 杂志文章
doi：
更新日期：2012-03-01 00:00:00
abstract：:Gastrointestinal stromal tumors (GISTs) are mesenchymal neoplasms most frequently found in the stomach and presenting without symptoms or with unspecific ones such as hemorrhage and abdominal pain. The malignant potential of GIST is variable and there are several prognostic indexes for treatment and follow up. The sup...
journal_title：Acta clinica Croatica
pub_type： 杂志文章
doi：
更新日期：2010-09-01 00:00:00
abstract：:Gallstone ileus with impaction of gallstone in distal duodenum is an extremely rare complication of cholecystolithiasis. Gallstone ileus in itself accounts for less than 1% of these complications with 800 cases described so far. However, there are less than 15 cases described with the impaction of gallstone in distal ...
journal_title：Acta clinica Croatica
pub_type： 杂志文章
doi：
更新日期：2010-09-01 00:00:00
abstract：:The aim of this study was to investigate the correlation of immunohistochemical expression of nm23 gene in colorectal cancer cells with tumor stage according to Dukes, tumor differentiation, occurrence of distant metastases and patient survival. This retrospective study included 100 colorectal cancer patients who unde...
journal_title：Acta clinica Croatica
pub_type： 杂志文章
doi：
更新日期：2012-03-01 00:00:00
abstract：:Heart rate variability (HRV) gives information on the sympathetic-parasympathetic autonomic balance. The aim of the study was to analyze sympathovagal balance after acute spinal cord injury (SCI), demonstrated by linear measures in time and frequency domain of HRV and to analyze the effect of corticosteroids on HRV pa...
journal_title：Acta clinica Croatica
pub_type： 杂志文章
doi：10.20471/acc.2016.55.02.08
更新日期：2016-06-01 00:00:00
abstract：:The aim of our study was to describe and interpret national trends in thyroid cancer in Croatian men and women during the 1988-2010 period, to better understand the incidence and mortality trends in comparison with other populations, and to determine the proportion of certain histologic subtypes of thyroid cancer and ...
journal_title：Acta clinica Croatica
pub_type： 杂志文章
doi：
更新日期：2015-03-01 00:00:00
abstract：:There are many false assumptions, both in the general population and among physicians, regarding the influence of radiation on pregnant patients and the fetus during diagnostic procedures, in spite of scientific facts based on studies. These false assumptions are mostly based on the idea that every diagnostic procedur...
journal_title：Acta clinica Croatica
pub_type： 杂志文章
doi：10.20471/acc.2016.55.02.10
更新日期：2016-06-01 00:00:00
abstract：:The principal iron storage protein is ferritin, which is primarily present in cytoplasm. The most common cause of hyperferritinemia is iron overload, which is either primary or secondary. Hyperferritinemia is commonly found in patients with chronic kidney disease regardless of their hemoglobin level and is often consi...
journal_title：Acta clinica Croatica
pub_type： 杂志文章
doi：
更新日期：2011-06-01 00:00:00
abstract：:Fetal alcohol syndrome is defined by a triad of symptoms such as facial dysmorphology, prenatal and postnatal growth deficiency, and central nervous system dysfunction. It is the result of teratogenic effects of alcohol consumption in pregnancy. The prevalence of fetal alcohol syndrome is 1 to 3 per 1000 live births. ...
journal_title：Acta clinica Croatica
pub_type： 杂志文章
doi：
更新日期：2014-03-01 00:00:00
abstract：:Head injuries are very common in children and are the most frequent cause of disability and death among children. This retrospective study included 350 children hospitalized for injury of neurocranium over a 5-year period at Dr Josip Bencević General Hospital in Slavonski Brod. Boys were more commonly injured (63.4%) ...
journal_title：Acta clinica Croatica
pub_type： 杂志文章
doi：
更新日期：2012-12-01 00:00:00
abstract：:Thrombolysis with intravenous recombinant tissue plasminogen activator (rtPA) is the first evidence based treatment for acute ischemic stroke, which aims to reduce the cerebrovascular lesion. At University Department of Neurology, Sestre milosrdnice University Hospital, Zagreb, thrombolytic therapy with intravenous rt...
journal_title：Acta clinica Croatica
pub_type： 杂志文章,多中心研究
doi：
更新日期：2009-09-01 00:00:00
abstract：:The aim of this prospective study was to evaluate whether cytokine levels in nasal secretions may be clinical parameters of severity of nasal polyposis. Forty nasal polyp patients (20 asthmatic and 20 nonasthmatic) requiring surgical treatment were included. Nasal secretion samples were collected from nasal cavities o...
journal_title：Acta clinica Croatica
pub_type： 杂志文章
doi：
更新日期：2010-12-01 00:00:00
abstract：:Chronic wounds on lower extremities most commonly result from chronic venous insufficiency. Chronic leg ulcer impacts the quality of life in a number of ways such as reduced mobility, pain, unpleasant odor, sleep disturbances, social isolation, etc. This study included 100 patients with chronic wounds/lower leg ulcer ...
journal_title：Acta clinica Croatica
pub_type： 杂志文章
doi：
更新日期：2015-09-01 00:00:00
abstract：:Histologic and radiologic studies describe intramyocardial fat tissue as a normal finding or as part of cardiac pathology. The role of fat cells within the myocardium is not fully understood. The aim of this study was to assess fat tissue distribution in the myocardium of right atrium (RA) and right ventricle (RV) and...
journal_title：Acta clinica Croatica
pub_type： 杂志文章
doi：10.20471/acc.2018.57.01.15
更新日期：2018-03-01 00:00:00
abstract：:Renal artery embolism is a disease that is easily missed due to its infrequent and nonspecific presentations. Although early diagnosis and optimal thrombolytic treatment can sometimes restore renal function, therapeutic guidelines have not yet been established. However, early anticoagulant therapy is beneficial and se...
journal_title：Acta clinica Croatica
pub_type： 杂志文章
doi：
更新日期：2014-06-01 00:00:00
abstract：:The incidence of heterotopic/ectopic pregnancy in recent times has increased partly due to the increase in assisted reproductive technologies, whereas such medical cases and cervical pregnancy in particular are extremely rare with spontaneous conception. We report on three patients referred to our department in one we...
journal_title：Acta clinica Croatica
pub_type： 杂志文章
doi：
更新日期：2015-09-01 00:00:00
abstract：:The rate of periprosthetic femoral fractures following total hip replacement has been growing steadily in the last 20 years and ranges from 0.1% to 2.1%. These fractures are mostly related to older patients with the presence of chronic diseases and frequently poor bone quality. The treatment is surgically very complex...
journal_title：Acta clinica Croatica
pub_type： 杂志文章
doi：10.20471/acc.2017.56.03.21
更新日期：2017-09-01 00:00:00
abstract：:The first beginnings of ophthalmic echography in Croatia started at the turn of the 1960s and 1970s. When the two largest medical institutions in Croatia, Sestre milosrdnice University Hospital (former Dr. Mladen Stojanović General Hospital) and Zagreb University Hospital Center, both in Zagreb, were supplied with ult...
journal_title：Acta clinica Croatica
pub_type： 历史文章,杂志文章
doi：
更新日期：2012-12-01 00:00:00
abstract：:The purpose of the article is to present the differential diagnostic criteria between pneumobilia (air in the biliary system) and portal vein gas on abdominal x-ray. Differential diagnosis is essential because of its influence on patient management. Two patients are presented, one with pneumobilia and the other with p...
journal_title：Acta clinica Croatica
pub_type： 杂志文章
doi：
更新日期：2013-09-01 00:00:00
abstract：:Cavernous malformations are classified as a group of vascular malformations of the central nervous system. Conservative treatment of brainstem cavernomas is accompanied with poor outcome. Surgery ofbrainstem cavernomas still poses a challenge due to the high risk of neurological damage and respectable morbidity. We re...
journal_title：Acta clinica Croatica
pub_type： 杂志文章
doi：
更新日期：2014-12-01 00:00:00
abstract：:Unicameral bone cysts (UBC) are benign bone tumor-like lesions. Mostly they are located in the metaphyseal-diaphyseal region of long bones in children and adolescents. The etiology of UBC is still unclear. There is no consensus about the protocol of UBC treatment. The aim of this study was to evaluate the effectivenes...
journal_title：Acta clinica Croatica
pub_type： 杂志文章
doi：10.20471/acc.2019.58.03.01
更新日期：2019-09-01 00:00:00
abstract：:Atrial fibrillation is the most common cardiac arrhythmia. It increases the risk of death and thromboembolic events. Vitamin K antagonists reduce these risks. Disadvantages of vitamin K antagonist therapy are narrow therapeutic range and interactions with drugs and food. In a single center prospective study, we enroll...
journal_title：Acta clinica Croatica
pub_type： 杂志文章
doi：10.20471/acc.2019.58.04.22
更新日期：2019-12-01 00:00:00
abstract：:A case of a 66-year-old man with West Nile neuroinvassive disease manifested with fever, weakness, fatigue, consciousness disorders and underlying diabetes mellitus type 2 and cardiovascular diseases is presented. Laboratory data showed elevated erythrocyte sedimentation rate and fibrinogen. Serological tests revealed...
journal_title：Acta clinica Croatica
pub_type：
doi：10.20471/acc.2019.58.03.21
更新日期：2019-09-01 00:00:00
