The Croatian Model of Integrative Prospective Management of Epilepsy and Pregnancy

Abstract:

:Epilepsy is the most common neurological complication in pregnancy. Women with epilepsy have a higher risk of complications in pregnancy. In Croatia, women with epilepsy are treated by neurologists at tertiary centers according to the place of residence. We prospectively followed-up pregnancies in women with epilepsy and healthy controls, and analyzed the factors responsible for their delivery outcomes and development of their babies. Healthy pregnant women had a higher level of education and economic status, but pregnant women with epilepsy took folic acid in a higher proportion than controls, possibly due to timely preconception counseling. Complications during pregnancy depended on the number of antiepileptic drugs and epilepsy control. We noticed some behavioral and cognitive aspects in children exposed in utero to valproic acid, which required follow up. The rate of congenital malformations was not increased. In conclusion, women with epilepsy should receive preconception counseling about the risk for pregnancy, but also about the possibilities to minimize that risk. We have introduced a model of integrative management of pregnancy and epilepsy based on close collaboration among different clinical experts in Croatia, in order to provide prompt counseling and timely intervention.

journal_name

Acta Clin Croat

journal_title

Acta clinica Croatica

authors

Miškov S,Gjergja Juraški R,Mikula I,Bašić S,Bošnjak Pašić M,Košec V,Sabol Z,Fučić A,Sajko T,Bašić Kes V

doi

10.20471/acc.2016.55.04.02

subject

Has Abstract

pub_date

2016-12-01 00:00:00

pages

535-548

issue

4

eissn

0353-9466

issn

1333-9451

journal_volume

55

pub_type

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