Abstract:
:Pelvic lymph node dissection (PLND) during radical prostatectomy (RP) is the most accurate staging modality for lymph node assessment in patients with prostate cancer. It is recommended in all patients with intermediate or high-risk disease undergoing radical prostatectomy. The goal of our study was to assess unfavorable clinicopathological characteristics in patients with omitted lymphadenectomy (PLND) during radical prostatectomy based on the nomogram proposed by Briganti and colleagues. In 2011, 200 patients undertook radical prostatectomy in our institution. Among them 53 patients who fulfilled Briganti criteria and in whom we omitted lymphadenectomy based on current guidelines. Unfavorable clinicopathological features considered were: stage T3, positive surgical margins or biochemical relapse (BCR). We registered biopsy Gleason score 6 in 34 patients, and 19 patients had Gleason score 7. Stage pT2 was seen in 49 patients, and pT3 in 4. Glea-son score after radical prostatectomy was upgraded from GS 6 to GS 7 in 20 patients (37%) and reduced in 1 patient (2%). After a median follow-up of 49 (44-56) months, there were 12 (22.6%) patients with BCR. Patients with biopsy Gleason score 6 (n=34) compared to biopsy Gleason 7 (n=19) patients showed no difference regarding positive margins (p=0.0738) and BCR (p=0,736) at 49 months follow-up. Thus, PLND according to current guidelines can be safely omitted in low-risk patients using Brigantinomogram.
journal_name
Acta Clin Croatjournal_title
Acta clinica Croaticaauthors
Tomašković I,Nikles S,Tomić M,Pezelj I,Svaguša I,Pirša M,Ružić Bdoi
10.20471/acc.2018.57.s1.09subject
Has Abstractpub_date
2018-10-01 00:00:00pages
61-65issue
Suppl 1eissn
0353-9466issn
1333-9451journal_volume
57pub_type
杂志文章abstract::Liposarcoma is one of the most common soft-tissue sarcomas in adults, but head and neck are rarely involved, especially regions of the larynx and hypopharynx. According to Enzinger and Weiss, liposarcoma can be divided into 5 subtypes: well-differentiated, myxoid, round cell, pleomorphic and dedifferentiated. We prese...
journal_title:Acta clinica Croatica
pub_type: 杂志文章,评审
doi:
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journal_title:Acta clinica Croatica
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journal_title:Acta clinica Croatica
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journal_title:Acta clinica Croatica
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journal_title:Acta clinica Croatica
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journal_title:Acta clinica Croatica
pub_type: 历史文章,杂志文章
doi:
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journal_title:Acta clinica Croatica
pub_type: 杂志文章
doi:10.20471/acc.2019.58.03.11
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journal_title:Acta clinica Croatica
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journal_title:Acta clinica Croatica
pub_type: 杂志文章
doi:10.20471/acc.2019.58.03.01
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journal_title:Acta clinica Croatica
pub_type: 杂志文章
doi:10.20471/acc.2016.55.04.02
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journal_title:Acta clinica Croatica
pub_type: 杂志文章
doi:10.20471/acc.2016.55.03.05
更新日期:2016-09-01 00:00:00
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journal_title:Acta clinica Croatica
pub_type: 杂志文章,评审
doi:10.20471/acc.2018.57.03.20
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journal_title:Acta clinica Croatica
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doi:10.20471/acc.2019.58.03.21
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journal_title:Acta clinica Croatica
pub_type: 杂志文章
doi:
更新日期:2009-03-01 00:00:00
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journal_title:Acta clinica Croatica
pub_type: 杂志文章,多中心研究
doi:
更新日期:2009-09-01 00:00:00
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journal_title:Acta clinica Croatica
pub_type: 杂志文章,评审
doi:10.20471/acc.2016.55.01.20
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journal_title:Acta clinica Croatica
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journal_title:Acta clinica Croatica
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journal_title:Acta clinica Croatica
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doi:10.20471/acc.2019.58.01.02
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journal_title:Acta clinica Croatica
pub_type: 杂志文章
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journal_title:Acta clinica Croatica
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