Abstract：
:The aim of the study was to assess the role of serum osteoprotegerin (OPG) as a biomarker in patients with aortic valve stenosis (AS) in relation to heart failure and symptomatic status. This was a case control study, which included 51 patients with AS and 39 control subjects. At the time of study enrolment, detailed medical history was obtained and all subjects underwent physical examination, chest x-ray and echocardiography. OPG levels were measured in all subjects, and serum N-terminal of the pro b-type natriuretic peptide (NT pro BNP) levels were determined in patients with AS. Serum OPG levels were elevated in patients with AS compared to control subjects (p=0.001). Patients with heart failure due to AS had elevated serum OPG levels in comparison to patients without heart failure (p=0.001). A significant correlation between OPG and symptomatic status was observed in all patients with AS (p<0.001), however, it was not the case in patients without heart failure (p=0.425). There was a positive correlation between OPG and NT pro BNP concentrations with objective signs of heart failure on chest x-ray (p<0.001). Negative correlation of OPG concentrations with aortic valve area was present (p<0.040), as well as with left ventricular ejection fraction (p<0.001). Serum OPG could be a valuable biomarker in the evaluation of severity of calcified AS and serve as an additional indicator besides clinical presentation and echocardiography in the assessment of surgical treatment or aortic valve replacement.
journal_name
Acta Clin Croatjournal_title
Acta clinica Croaticaauthors
Makarović S,Makarović Z,Bilić-Ćurčić I,Milas-Ahić J,Mihaljević I,Franceschi M,Jukić Tdoi
10.20471/acc.2017.56.04.22subject
Has Abstractpub_date
2017-12-01 00:00:00pages
733-741issue
4eissn
0353-9466issn
1333-9451journal_volume
56pub_type
杂志文章abstract：:The aim of the study was to assess how children and adolescents experience hospitalization and separation from their parents, their home and daily activities, in order to improve the psychosocial quality of hospital stay. Emotions and experiences reported by hospitalized children and adolescents are presented and disc...
journal_title：Acta clinica Croatica
pub_type： 杂志文章
doi：
更新日期：2009-06-01 00:00:00
abstract：:The principal iron storage protein is ferritin, which is primarily present in cytoplasm. The most common cause of hyperferritinemia is iron overload, which is either primary or secondary. Hyperferritinemia is commonly found in patients with chronic kidney disease regardless of their hemoglobin level and is often consi...
journal_title：Acta clinica Croatica
pub_type： 杂志文章
doi：
更新日期：2011-06-01 00:00:00
abstract：:The aim was to determine the validity of the international normalized ratio (INR) and prothrombin time (PT) as a monitor for warfarin therapy in patients with lupus anticoagulants and recurrent thrombosis, and to investigate alternative approaches to monitoring warfarin therapy and new treatment options in these patie...
journal_title：Acta clinica Croatica
pub_type： 杂志文章,评审
doi：
更新日期：2010-12-01 00:00:00
abstract：:In this article, we document a conclusive case of nebivolol-induced hyperkalemia for the first time in the known medical literature. Hyperkalemia is associated with serious conditions such as cardiac arrhythmias and sudden cardiac death. Nebivolol was not known to cause hyperkalemia, and this event is not listed in it...
journal_title：Acta clinica Croatica
pub_type： 杂志文章
doi：10.20471/acc.2016.55.04.20
更新日期：2016-12-01 00:00:00
abstract：:Hepatic encephalopathy (HE) is a brain dysfunction caused by liver failure. Clinically, it can manifests as a wide spectrum of neurological or psychiatric abnormalities. This report presents a case of a 43-year-old male with HE and asymmetric kinetic, postural and resting tremor of upper extremities. Magnetic resonanc...
journal_title：Acta clinica Croatica
pub_type： 杂志文章
doi：10.20471/acc.2018.57.01.25
更新日期：2018-03-01 00:00:00
abstract：:Chemical peels are growing in popularity with new agents, formulas and methods giving them greater reliability and safety. Although the operative procedure may seem relatively simple, proper knowledge and skills of the physician and education of the patient is crucial. It is very important for the physician to know ch...
journal_title：Acta clinica Croatica
pub_type： 杂志文章
doi：
更新日期：2010-12-01 00:00:00
abstract：:A case of a 66-year-old man with West Nile neuroinvassive disease manifested with fever, weakness, fatigue, consciousness disorders and underlying diabetes mellitus type 2 and cardiovascular diseases is presented. Laboratory data showed elevated erythrocyte sedimentation rate and fibrinogen. Serological tests revealed...
journal_title：Acta clinica Croatica
pub_type：
doi：10.20471/acc.2019.58.03.21
更新日期：2019-09-01 00:00:00
abstract：:Pelvic lymph node dissection (PLND) during radical prostatectomy (RP) is the most accurate staging modality for lymph node assessment in patients with prostate cancer. It is recommended in all patients with intermediate or high-risk disease undergoing radical prostatectomy. The goal of our study was to assess unfavora...
journal_title：Acta clinica Croatica
pub_type： 杂志文章
doi：10.20471/acc.2018.57.s1.09
更新日期：2018-10-01 00:00:00
abstract：:Thrombolysis with intravenous recombinant tissue plasminogen activator (rtPA) is the first evidence based treatment for acute ischemic stroke, which aims to reduce the cerebrovascular lesion. At University Department of Neurology, Sestre milosrdnice University Hospital, Zagreb, thrombolytic therapy with intravenous rt...
journal_title：Acta clinica Croatica
pub_type： 杂志文章,多中心研究
doi：
更新日期：2009-09-01 00:00:00
abstract：:A 57-year-old multiparous housewife was hospitalized at University Clinical Center with painless, ulcerated, huge tumor of the vulva, which had progressively increased in size during the last five years. It was a firm, ulcerated mass involving the left vulva and measuring 35 cm in diameter. The vaginal orifice was dev...
journal_title：Acta clinica Croatica
pub_type： 杂志文章
doi：
更新日期：2015-06-01 00:00:00
abstract：:Lumbar discectomy is the most common surgical treatment for intervertebral disc extrusion. Postoperative pain is a common clinical problem that greatly affects the length of hospitalization, functional status and patient quality of life. Th e aim of this study was to compare the postoperative analgesic effi cacy of pa...
journal_title：Acta clinica Croatica
pub_type： 杂志文章,随机对照试验
doi：10.20471/acc.2017.56.02.06
更新日期：2017-06-01 00:00:00
abstract：:Findings obtained by fluorine-18-fluorodeoxyglucose positron emission tomography (18F-FDG PET) and computed tomography (CT) were compared in patients with malignant lymphoma and colorectal carcinoma. In 14 malignant lymphoma patients, 16 18F-FDG PET procedures were performed to assess chemotherapy and/or radiotherapy ...
journal_title：Acta clinica Croatica
pub_type： 杂志文章
doi：
更新日期：2009-03-01 00:00:00
abstract：:The management of postoperative pain after carpal tunnel syndrome surgical treatment at a tertiary hospital was analyzed and compared with the guidelines for perioperative pain management. This retrospective study included 579 patients operated on for carpal tunnel syndrome at the Split University Hospital Center in S...
journal_title：Acta clinica Croatica
pub_type： 杂志文章
doi：10.20471/acc.2017.56.03.11
更新日期：2017-09-01 00:00:00
abstract：:The prevalence of uterine myomas during pregnancy is estimated to range from 0.3% to 2.6%. Although leiomyomas usually remain asymptomatic, in one often cases they may be complicated. The management of uterine fibroids during pregnancy is largely conservative and surgical removal is generally delayed until post partum...
journal_title：Acta clinica Croatica
pub_type： 杂志文章
doi：
更新日期：2010-06-01 00:00:00
abstract：:Stress is the key psychological activator of the hypothalamic-pituitary-adrenal axis and therefore an important risk factor for diminished immunocompetence. The aim of the study was to assess the connection between the strategies of coping with stress and lymphocyte counts in soldiers. Coping strategies were evaluated...
journal_title：Acta clinica Croatica
pub_type： 杂志文章
doi：
更新日期：2010-06-01 00:00:00
abstract：:The aim of the study was to assess the situation with implantation of cardiac pacemakers and to critically evaluate the possibility of this method of treatment. The study was conducted from 2001 to 2007. Data on a total of 211 operations were included in the study. There were 121 (57.3%) male patients, mean age 69.7 y...
journal_title：Acta clinica Croatica
pub_type： 杂志文章
doi：
更新日期：2008-12-01 00:00:00
abstract：:Reverse shoulder prosthesis has become one of the most often used prosthetic implants in shoulder replacement surgery. It has a wide spectrum of indications, starting from comminuted humeral fractures and posttraumatic arthritis to arthritis caused by the rotator cuff loss. Its application at our hospital began in 200...
journal_title：Acta clinica Croatica
pub_type： 杂志文章
doi：
更新日期：2014-09-01 00:00:00
abstract：:The aim of the study was to identify differences in baseline characteristics and outcomes of men and women with acute ischemic stroke. Ischemic stroke was confirmed by CT scan or autopsy in patients admitted to the 2nd Department of Neurology, Institute of Psychiatry and Neurology in Warsaw, Poland from 1995 to 2007. ...
journal_title：Acta clinica Croatica
pub_type： 杂志文章
doi：
更新日期：2011-03-01 00:00:00
abstract：:The aim of this study was to evaluate the implementation of the 9th edition of the American College of Chest Physicians (ACCP9) guidelines for prevention of venous thromboembolism in nonsurgical patients in clinical practice in one university and one general Croatian hospital. A retrospective study was conducted at Za...
journal_title：Acta clinica Croatica
pub_type： 杂志文章
doi：10.20471/acc.2017.56.04.12
更新日期：2017-12-01 00:00:00
abstract：:The aim of the study was to investigate the association between some lifestyle-attributable risk factors of atherosclerosis, such as body mass index (BMI), oral contraceptives, hormone replacement therapy, smoking and alcohol consumption with breast arterial calcification (BAC) and its intensity on mammograms, and to ...
journal_title：Acta clinica Croatica
pub_type： 杂志文章
doi：
更新日期：2015-06-01 00:00:00
abstract：:Liposarcoma is one of the most common soft-tissue sarcomas in adults, but head and neck are rarely involved, especially regions of the larynx and hypopharynx. According to Enzinger and Weiss, liposarcoma can be divided into 5 subtypes: well-differentiated, myxoid, round cell, pleomorphic and dedifferentiated. We prese...
journal_title：Acta clinica Croatica
pub_type： 杂志文章,评审
doi：
更新日期：2014-09-01 00:00:00
abstract：:The first beginnings of ophthalmic echography in Croatia started at the turn of the 1960s and 1970s. When the two largest medical institutions in Croatia, Sestre milosrdnice University Hospital (former Dr. Mladen Stojanović General Hospital) and Zagreb University Hospital Center, both in Zagreb, were supplied with ult...
journal_title：Acta clinica Croatica
pub_type： 历史文章,杂志文章
doi：
更新日期：2012-12-01 00:00:00
abstract：:Epilepsy is the most common neurological complication in pregnancy. Women with epilepsy have a higher risk of complications in pregnancy. In Croatia, women with epilepsy are treated by neurologists at tertiary centers according to the place of residence. We prospectively followed-up pregnancies in women with epilepsy ...
journal_title：Acta clinica Croatica
pub_type： 杂志文章
doi：10.20471/acc.2016.55.04.02
更新日期：2016-12-01 00:00:00
abstract：:Renal artery embolism is a disease that is easily missed due to its infrequent and nonspecific presentations. Although early diagnosis and optimal thrombolytic treatment can sometimes restore renal function, therapeutic guidelines have not yet been established. However, early anticoagulant therapy is beneficial and se...
journal_title：Acta clinica Croatica
pub_type： 杂志文章
doi：
更新日期：2014-06-01 00:00:00
abstract：:Gallstone ileus with impaction of gallstone in distal duodenum is an extremely rare complication of cholecystolithiasis. Gallstone ileus in itself accounts for less than 1% of these complications with 800 cases described so far. However, there are less than 15 cases described with the impaction of gallstone in distal ...
journal_title：Acta clinica Croatica
pub_type： 杂志文章
doi：
更新日期：2010-09-01 00:00:00
abstract：:Helicobacter pylori (H. pylori) is a common problem and a significant cause of chronic gastric inflammation. H. pylori, ongoing gastric inflammation and its severity are the most critical component of precursors of gastric cancer. Hypothetically, every chronic tissue injury activates platelets, and the mean platelet v...
journal_title：Acta clinica Croatica
pub_type： 杂志文章,评审
doi：10.20471/acc.2019.58.04.02
更新日期：2019-12-01 00:00:00
abstract：:The aim of this paper is to present epidemiological features of reported patients with invasive meningococcal disease in the Split-Dalmatia County in the period from January 1996 to December 2010. During the 15-year period (1996-2010), a total of 119 patients were reported to have invasive meningococcal disease, yield...
journal_title：Acta clinica Croatica
pub_type： 杂志文章
doi：
更新日期：2013-12-01 00:00:00
abstract：:Foreign body ingestion is a common problem in children, but magnet ingestion is relatively rare. However, when it occurs, it tends to have a high rate of complications. This is a case report of a 3-year-old child who swallowed multiple magnetic toys, subsequently developing jejunoileal perforation and volvulus. This c...
journal_title：Acta clinica Croatica
pub_type： 杂志文章
doi：
更新日期：2015-03-01 00:00:00
abstract：:The purpose of the study was to point to occupational exposure of dental medicine doctors in Croatia and to the effect of static performance on developing venous disease. The study included 120 subjects, 60 of them doctors of dental medicine and 60 from other professions. The study was focused on finding a way to upgr...
journal_title：Acta clinica Croatica
pub_type： 杂志文章
doi：
更新日期：2014-03-01 00:00:00
abstract：:Airway management in a polytraumatized patient with severe spinal and thoracic deformities demands detailed investigation of anatomical characteristics of the head, neck and airways, as well as thoracic configuration, before attempting endotracheal intubation. This enables the physician to predict a difficult airway a...
journal_title：Acta clinica Croatica
pub_type： 杂志文章
doi：
更新日期：2012-09-01 00:00:00
