Abstract：
:Multiple sclerosis (MS) is a multicomponent disease characterized by inflammation, neurodegeneration, and cancellation of the central nervous system recovery mechanisms. The cause of MS is still unknown, but it is undeniable that genetic, environmental and immune factors are involved in the etiopathogenesis of this complex and heterogeneous disease. From the aspect of immunopathogenesis, until recently the opinion prevailed that autoreactive T lymphocytes played a major role, the activation of which is a key step in MS. The knowledge of the effector and regulatory roles of B cells supports a new concept of MS immunopathogenesis that is based on the highly com-plex interaction of T and B cells, with B cells actively participating in cellular immunity by directing the intensity and quality of cellular immune response. The mechanisms of B cell activity in MS immunopathogenesis are multiple and include antigen presentation and T cell costimulation, cytokine secretion, antibody synthesis, and formation of ectopic lymphoid B cell aggregates in the intrameningeal spaces. The importance of B cells has been confirmed by modern therapeutic options for the treatment of MS.
journal_name
Acta Clin Croatjournal_title
Acta clinica Croaticaauthors
Lazibat I,Rubinić Majdak M,Županić Sdoi
10.20471/acc.2018.57.02.17subject
Has Abstractpub_date
2018-06-01 00:00:00pages
352-361issue
2eissn
0353-9466issn
1333-9451journal_volume
57pub_type
杂志文章,评审abstract：:The aim of this study was to determine the correlation between the static and dynamic occlusal factors in patients with anterior disk displacement (DD) and to compare it with occlusion in asymptomatic individuals. The study included a group of 40 patients with DD (median age 35.5) and a control group of 25 students of...
journal_title：Acta clinica Croatica
pub_type： 杂志文章
doi：
更新日期：2008-09-01 00:00:00
abstract：:Foreign body ingestion is a common problem in children, but magnet ingestion is relatively rare. However, when it occurs, it tends to have a high rate of complications. This is a case report of a 3-year-old child who swallowed multiple magnetic toys, subsequently developing jejunoileal perforation and volvulus. This c...
journal_title：Acta clinica Croatica
pub_type： 杂志文章
doi：
更新日期：2015-03-01 00:00:00
abstract：:Terson's syndrome describes the concurrence of intracranial hemorrhage, vitreous hemorrhage and juxtapapillary subinternal limiting membrane and retinal hemorrhage. In most cases, the retinal and vitreous hemorrhage will clear spontaneously. Vitrectomy was indicated by persistent hemorrhage in two cases. Ultrasound wa...
journal_title：Acta clinica Croatica
pub_type： 杂志文章
doi：
更新日期：2012-12-01 00:00:00
abstract：:We present an isolate of Klebsiella pneumoniae OXA-48 isolated in a 68-year-old man who underwent radical prostatectomy due to prostate cancer. The antibiotic susceptibility testing to a wide range of antibiotics was performed by disk diffusion method and determination of minimal inhibitory concentrations. The isolate...
journal_title：Acta clinica Croatica
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doi：10.20471/acc.2017.56.01.23
更新日期：2017-03-01 00:00:00
abstract：:Airway management in a polytraumatized patient with severe spinal and thoracic deformities demands detailed investigation of anatomical characteristics of the head, neck and airways, as well as thoracic configuration, before attempting endotracheal intubation. This enables the physician to predict a difficult airway a...
journal_title：Acta clinica Croatica
pub_type： 杂志文章
doi：
更新日期：2012-09-01 00:00:00
abstract：:Stress is the key psychological activator of the hypothalamic-pituitary-adrenal axis and therefore an important risk factor for diminished immunocompetence. The aim of the study was to assess the connection between the strategies of coping with stress and lymphocyte counts in soldiers. Coping strategies were evaluated...
journal_title：Acta clinica Croatica
pub_type： 杂志文章
doi：
更新日期：2010-06-01 00:00:00
abstract：:Lumbar discectomy is the most common surgical treatment for intervertebral disc extrusion. Postoperative pain is a common clinical problem that greatly affects the length of hospitalization, functional status and patient quality of life. Th e aim of this study was to compare the postoperative analgesic effi cacy of pa...
journal_title：Acta clinica Croatica
pub_type： 杂志文章,随机对照试验
doi：10.20471/acc.2017.56.02.06
更新日期：2017-06-01 00:00:00
abstract：:Angiogenesis is essential for the development, growth and progression of tumors. Although vascular endothelial growth factor (VEGF) is a well-known proangiogenic factor, its impact on lymphoma has not yet been fully clarified. The aim of this study was to evaluate VEGF-A -expression and microvessel density (MVD) in ag...
journal_title：Acta clinica Croatica
pub_type： 杂志文章
doi：10.20471/acc.2017.56.04.02
更新日期：2017-12-01 00:00:00
abstract：:The aim of our study was to describe and interpret national trends in thyroid cancer in Croatian men and women during the 1988-2010 period, to better understand the incidence and mortality trends in comparison with other populations, and to determine the proportion of certain histologic subtypes of thyroid cancer and ...
journal_title：Acta clinica Croatica
pub_type： 杂志文章
doi：
更新日期：2015-03-01 00:00:00
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journal_title：Acta clinica Croatica
pub_type： 杂志文章,评审
doi：
更新日期：2013-06-01 00:00:00
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journal_title：Acta clinica Croatica
pub_type： 杂志文章
doi：
更新日期：2011-09-01 00:00:00
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journal_title：Acta clinica Croatica
pub_type： 杂志文章,评审
doi：
更新日期：2012-09-01 00:00:00
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journal_title：Acta clinica Croatica
pub_type： 杂志文章,评审
doi：10.20471/acc.2019.58.04.02
更新日期：2019-12-01 00:00:00
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journal_title：Acta clinica Croatica
pub_type： 杂志文章
doi：
更新日期：2013-03-01 00:00:00
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journal_title：Acta clinica Croatica
pub_type： 杂志文章
doi：10.20471/acc.2016.55.04.02
更新日期：2016-12-01 00:00:00
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journal_title：Acta clinica Croatica
pub_type： 杂志文章
doi：
更新日期：2010-06-01 00:00:00
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journal_title：Acta clinica Croatica
pub_type： 杂志文章
doi：
更新日期：2014-12-01 00:00:00
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journal_title：Acta clinica Croatica
pub_type： 杂志文章
doi：
更新日期：2010-09-01 00:00:00
abstract：:Thrombolysis with intravenous recombinant tissue plasminogen activator (rtPA) is the first evidence based treatment for acute ischemic stroke, which aims to reduce the cerebrovascular lesion. At University Department of Neurology, Sestre milosrdnice University Hospital, Zagreb, thrombolytic therapy with intravenous rt...
journal_title：Acta clinica Croatica
pub_type： 杂志文章,多中心研究
doi：
更新日期：2009-09-01 00:00:00
abstract：:Heart rate variability (HRV) gives information on the sympathetic-parasympathetic autonomic balance. The aim of the study was to analyze sympathovagal balance after acute spinal cord injury (SCI), demonstrated by linear measures in time and frequency domain of HRV and to analyze the effect of corticosteroids on HRV pa...
journal_title：Acta clinica Croatica
pub_type： 杂志文章
doi：10.20471/acc.2016.55.02.08
更新日期：2016-06-01 00:00:00
abstract：:Person-oriented medicine is characterized by a holistic approach in patient ma- nagement that embraces physical, psychological, social and spiritual aspects of health and dise- ase. It responds to the needs of patients and health care workers to form an effective therapeutic relationship based on trust, empathy, compa...
journal_title：Acta clinica Croatica
pub_type： 杂志文章,评审
doi：
更新日期：2014-12-01 00:00:00
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journal_title：Acta clinica Croatica
pub_type： 杂志文章
doi：10.20471/acc.2020.59.02.06
更新日期：2020-06-01 00:00:00
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journal_title：Acta clinica Croatica
pub_type： 杂志文章
doi：
更新日期：2011-03-01 00:00:00
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journal_title：Acta clinica Croatica
pub_type： 杂志文章
doi：
更新日期：2015-12-01 00:00:00
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journal_title：Acta clinica Croatica
pub_type： 杂志文章
doi：10.20471/acc.2018.57.01.15
更新日期：2018-03-01 00:00:00
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journal_title：Acta clinica Croatica
pub_type： 杂志文章
doi：
更新日期：2014-06-01 00:00:00
abstract：:The aim of this prospective study was to evaluate whether cytokine levels in nasal secretions may be clinical parameters of severity of nasal polyposis. Forty nasal polyp patients (20 asthmatic and 20 nonasthmatic) requiring surgical treatment were included. Nasal secretion samples were collected from nasal cavities o...
journal_title：Acta clinica Croatica
pub_type： 杂志文章
doi：
更新日期：2010-12-01 00:00:00
abstract：:Botryoid cyst, a rare type of odontogenic cyst, is usually considered a multilocular variant of lateral periodontal cyst. It was first described in 1973, and up to the present less than a hundred cases have been reported in the literature. Botryoid cysts are characterized by a multilocular histologic finding and a hig...
journal_title：Acta clinica Croatica
pub_type： 杂志文章
doi：10.20471/acc.2016.55.03.24
更新日期：2016-09-01 00:00:00
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journal_title：Acta clinica Croatica
pub_type： 杂志文章
doi：10.20471/acc.2019.58.03.11
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abstract：:Findings obtained by fluorine-18-fluorodeoxyglucose positron emission tomography (18F-FDG PET) and computed tomography (CT) were compared in patients with malignant lymphoma and colorectal carcinoma. In 14 malignant lymphoma patients, 16 18F-FDG PET procedures were performed to assess chemotherapy and/or radiotherapy ...
journal_title：Acta clinica Croatica
pub_type： 杂志文章
doi：
更新日期：2009-03-01 00:00:00
