当前位置： SCI文献检索 > Scientific Reports期刊下所有文献 > An archaeal RNA binding protein, FAU-1, is a novel ribonuclease related to rRNA stability in Pyrococcus and Thermococcus.

An archaeal RNA binding protein, FAU-1, is a novel ribonuclease related to rRNA stability in Pyrococcus and Thermococcus.

Abstract：

:Ribosome biogenesis and turnover are processes necessary for cell viability and proliferation, and many kinds of proteins are known to regulate these processes. However, many questions still remain, especially in the Archaea. Generally, several ribonucleases are required to process precursor rRNAs to their mature forms, and to degrade rRNAs for quality control. Here, we found that FAU-1, which is known to be an RNA binding protein, possesses an RNase activity against precursor 5S rRNA derived from P. furiosus and T. kodakarensis in the order Thermococcales in vitro. An in vitro analysis revealed that UA sequences in the upstream of 5S rRNA were preferentially degraded by addition of FAU-1. Moreover, a fau-1 gene deletion mutant of T. kodakarensis showed a delay of exponential phase, reduction of maximum cell number and significant changes in the nucleotide sequence lengths of its 5S, 16S, and 23S rRNAs in early exponential phase. Our results suggest that FAU-1 is a potential RNase involved in rRNA stability through maturation and/or degradation processes.

journal_name

Sci Rep

journal_title

Scientific reports

authors

Ikeda Y,Okada Y,Sato A,Kanai T,Tomita M,Atomi H,Kanai A

doi

10.1038/s41598-017-13062-3

subject

Has Abstract

pub_date

2017-10-04 00:00:00

pages

12674

issue

1

issn

2045-2322

pii

10.1038/s41598-017-13062-3

journal_volume

7

pub_type

杂志文章

相关文献

Scientific Reports文献大全
  • Birth size and gestational age in opposite-sex twins as compared to same-sex twins: An individual-based pooled analysis of 21 cohorts.

    abstract：:It is well established that boys are born heavier and longer than girls, but it remains unclear whether birth size in twins is affected by the sex of their co-twin. We conducted an individual-based pooled analysis of 21 twin cohorts in 15 countries derived from the COllaborative project of Development of Anthropometri...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-018-24634-2

    authors： Jelenkovic A,Sund R,Yokoyama Y,Hur YM,Ullemar V,Almqvist C,Magnusson PK,Willemsen G,Bartels M,Beijsterveldt CEV,Bogl LH,Pietiläinen KH,Vuoksimaa E,Ji F,Ning F,Pang Z,Nelson TL,Whitfield KE,Rebato E,Llewellyn CH,Fi

    更新日期：2018-04-19 00:00:00

  • Transformation of nonencapsulated Streptococcus pneumoniae during systemic infection.

    abstract：:Streptococcus pneumoniae (pneumococcus) is a principal cause of bacterial middle ear infections, pneumonia, and meningitis. Capsule-targeted pneumococcal vaccines have likely contributed to increased carriage of nonencapsulated S. pneumoniae (NESp). Some NESp lineages are associated with highly efficient DNA uptake an...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-020-75988-5

    authors： Bradshaw JL,Rafiqullah IM,Robinson DA,McDaniel LS

    更新日期：2020-11-03 00:00:00

  • Dysmenorrhea increased the risk of postpartum depression in Chinese Han parturients.

    abstract：:Several studies have shown that dysmenorrhea increased the risk of depression. However, the association between dysmenorrhea and postpartum depression (PPD) is unclear. The purpose of this study is to evaluate the effects of dysmenorrhea on the development of PPD among Chinese women. A case-control study was performed...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-019-53059-8

    authors： Meng L,Li J,Cheng Y,Wei T,Du Y,Peng S

    更新日期：2019-11-12 00:00:00

  • Corrigendum: HIV-1 Env associates with HLA-C free-chains at the cell membrane modulating viral infectivity.

    abstract：:This corrects the article DOI: 10.1038/srep40037. ...

    journal_title：Scientific reports

    pub_type： 已发布勘误

    doi：10.1038/srep46991

    authors： Serena M,Parolini F,Biswas P,Sironi F,Blanco Miranda A,Zoratti E,Scupoli MT,Ziglio S,Valenzuela-Fernandez A,Gibellini D,Romanelli MG,Siccardi A,Malnati M,Beretta A,Zipeto D

    更新日期：2018-05-22 00:00:00

  • Identification of spoilage microorganisms in blueberry juice and their inactivation by a microchip pulsed electric field system.

    abstract：:Blueberry juice is a healthy and nutritious food that has become increasingly popular worldwide. However, little is known about the microbial groups of this juice that can cause its spoilage. This study aimed to identify the main spoilage microorganisms in blueberry juice and explore whether a microchip pulsed electri...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-018-26513-2

    authors： Zhu N,Yu N,Zhu Y,Wei Y,Hou Y,Zhang H,Sun AD

    更新日期：2018-05-25 00:00:00

  • Ultra-sensitive detection of kanamycin for food safety using a reduced graphene oxide-based fluorescent aptasensor.

    abstract：:Overuse of antibiotics has caused serious problems, such as appearance of super bacteria, whose accumulation in the human body through the food chain is a concern. Kanamycin is a common antibiotic used to treat diverse infections; however, residual kanamycin can cause many side effects in humans. Thus, development of ...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/srep40305

    authors： Ha NR,Jung IP,La IJ,Jung HS,Yoon MY

    更新日期：2017-01-05 00:00:00

  • Structural genomics applied to the rust fungus Melampsora larici-populina reveals two candidate effector proteins adopting cystine knot and NTF2-like protein folds.

    abstract：:Rust fungi are plant pathogens that secrete an arsenal of effector proteins interfering with plant functions and promoting parasitic infection. Effectors are often species-specific, evolve rapidly, and display low sequence similarities with known proteins. How rust fungal effectors function in host cells remains elusi...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-019-53816-9

    authors： de Guillen K,Lorrain C,Tsan P,Barthe P,Petre B,Saveleva N,Rouhier N,Duplessis S,Padilla A,Hecker A

    更新日期：2019-12-02 00:00:00

  • Experimental realization of controlled quantum teleportation of arbitrary qubit states via cluster states.

    abstract：:Controlled quantum teleportation involves a third party as a controller for the teleportation of state. Here, we present the novel protocols for controlling teleportation of the arbitrary two-qubit and three-qubit states through five-qubit and seven-qubit cluster states respectively. In these schemes, Alice sends the ...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-020-70446-8

    authors： Kumar A,Haddadi S,Pourkarimi MR,Behera BK,Panigrahi PK

    更新日期：2020-08-12 00:00:00

  • Composition of the white precipitate formed on the surface of damaged triacetyl cellulose-based motion picture films.

    abstract：:To achieve a better understanding of the "vinegar syndrome" phenomenon, which has caused serious damage to triacetyl cellulose-based motion picture films, the white powder obtained from damaged film surfaces was analysed in this study. The powder was found to be soluble in acetone, diethyl ether, dimethylformamide, an...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-020-80498-5

    authors： Takahashi K,Sasaki M,Hayakawa H,Yajima H,Oda Y

    更新日期：2021-01-15 00:00:00

  • Convolutional Neural Networks enable efficient, accurate and fine-grained segmentation of plant species and communities from high-resolution UAV imagery.

    abstract：:Recent technological advances in remote sensing sensors and platforms, such as high-resolution satellite imagers or unmanned aerial vehicles (UAV), facilitate the availability of fine-grained earth observation data. Such data reveal vegetation canopies in high spatial detail. Efficient methods are needed to fully harn...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-019-53797-9

    authors： Kattenborn T,Eichel J,Fassnacht FE

    更新日期：2019-11-27 00:00:00

  • Annexin-A1 enhances breast cancer growth and migration by promoting alternative macrophage polarization in the tumour microenvironment.

    abstract：:Macrophages are potent immune cells with well-established roles in the response to stress, injury, infection and inflammation. The classically activated macrophages (M1) are induced by lipopolysaccharide (LPS) and express a wide range of pro-inflammatory genes. M2 macrophages are induced by T helper type 2 cytokines s...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-017-17622-5

    authors： Moraes LA,Kar S,Foo SL,Gu T,Toh YQ,Ampomah PB,Sachaphibulkij K,Yap G,Zharkova O,Lukman HM,Fairhurst AM,Kumar AP,Lim LHK

    更新日期：2017-12-20 00:00:00

  • High Energy electron and proton acceleration by circularly polarized laser pulse from near critical density hydrogen gas target.

    abstract：:Relativistic electron rings hold the possibility of very high accelerating rates, and hopefully a relatively cheap and compact accelerator/collimator for ultrahigh energy proton source. In this work, we investigate the generation of helical shaped quasi-monoenergetic relativistic electron beam and high-energy proton b...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-018-20506-x

    authors： Sharma A

    更新日期：2018-02-01 00:00:00

  • dendPoint: a web resource for dendrimer pharmacokinetics investigation and prediction.

    abstract：:Nanomedicine development currently suffers from a lack of efficient tools to predict pharmacokinetic behavior without relying upon testing in large numbers of animals, impacting success rates and development costs. This work presents dendPoint, the first in silico model to predict the intravenous pharmacokinetics of d...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-019-51789-3

    authors： Kaminskas LM,Pires DEV,Ascher DB

    更新日期：2019-10-29 00:00:00

  • Generation of interconnected vesicles in a liposomal cell model.

    abstract：:We introduce an experimental method based upon a glass micropipette microinjection technique for generating a multitude of interconnected vesicles (IVs) in the interior of a single giant unilamellar phospholipid vesicle (GUV) serving as a cell model system. The GUV membrane, consisting of a mixture of soybean polar li...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-020-70562-5

    authors： Ali Doosti B,Fjällborg D,Kustanovich K,Jesorka A,Cans AS,Lobovkina T

    更新日期：2020-08-20 00:00:00

  • Dependency of Queensland and the Great Barrier Reef's tropical fisheries on reef-associated fish.

    abstract：:Coral reefs have been subject to mass coral bleaching, potentially causing rapid and widespread degradation of ecosystem services that depend on live coral cover, such as fisheries catch. Fisheries species in tropical waters associate with a wide range of habitats, so assessing the dependency of fisheries on coral ree...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-020-74652-2

    authors： Brown CJ,Taylor W,Wabnitz CCC,Connolly RM

    更新日期：2020-10-20 00:00:00

  • Structural Luneburg lens for broadband cloaking and wave guiding.

    abstract：:In this paper, we explore the concept of structural Luneburg lens (SLL) as a design framework for performing dynamic structural tailoring to obtain a structural wave cloak and a structural waveguide. The SLL is a graded refractive index lens, which is realized by using a variable thickness structure defined in a thin ...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-020-71124-5

    authors： Zhao L,Yu M

    更新日期：2020-09-03 00:00:00

  • The evolution of the macrophage-specific enhancer (Fms intronic regulatory element) within the CSF1R locus of vertebrates.

    abstract：:The Csf1r locus encodes the receptor for macrophage colony-stimulating factor, which controls the proliferation, differentiation and survival of macrophages. The 300 bp Fms intronic regulatory element (FIRE), within the second intron of Csf1r, is necessary and sufficient to direct macrophage-specific transcription. We...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-017-15999-x

    authors： Hume DA,Wollscheid-Lengeling E,Rojo R,Pridans C

    更新日期：2017-12-07 00:00:00

  • Two novel fish paralogs provide insights into the Rid family of imine deaminases active in pre-empting enamine/imine metabolic damage.

    abstract：:Reactive Intermediate Deaminase (Rid) protein superfamily includes eight families among which the RidA is conserved in all domains of life. RidA proteins accelerate the deamination of the reactive 2-aminoacrylate (2AA), an enamine produced by some pyridoxal phosphate (PLP)-dependent enzymes. 2AA accumulation inhibits ...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-020-66663-w

    authors： Digiovanni S,Visentin C,Degani G,Barbiroli A,Chiara M,Regazzoni L,Di Pisa F,Borchert AJ,Downs DM,Ricagno S,Vanoni MA,Popolo L

    更新日期：2020-06-23 00:00:00

  • Optimization of a MT1-MMP-targeting Peptide and Its Application in Near-infrared Fluorescence Tumor Imaging.

    abstract：:Membrane type 1 metalloproteinase (MT1-MMP) is an important regulator of cancer invasion, growth and angiogenesis, thus making it an attractive target for cancer imaging and therapy. A non-substrate peptide (MT1-AF7p) that bonded to the "MT-Loop" region of MT1-MMP was identified by using a phage-displayed peptide libr...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-018-28493-9

    authors： Ren L,Wang Y,Zhu L,Shen L,Zhang J,Wang J,Li H,Zheng Q,Yu D,Fang X

    更新日期：2018-07-09 00:00:00

  • Protein structure shapes immunodominance in the CD4 T cell response to yellow fever vaccination.

    abstract：:The live attenuated yellow fever (YF) vaccine is a highly effective human vaccine and induces long-term protective neutralizing antibodies directed against the viral envelope protein E. The generation of such antibodies requires the help of CD4 T cells which recognize peptides derived from proteins in virus particles ...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-017-09331-w

    authors： Koblischke M,Mackroth MS,Schwaiger J,Fae I,Fischer G,Stiasny K,Heinz FX,Aberle JH

    更新日期：2017-08-21 00:00:00

  • Elevated plasma abscisic acid is associated with asymptomatic falciparum malaria and with IgG-/caspase-1-dependent immunity in Plasmodium yoelii-infected mice.

    abstract：:Abscisic acid (ABA) is an ancient stress hormone and is detectable in a wide variety of organisms where it regulates innate immunity and inflammation. Previously, we showed that oral supplementation with ABA decreased parasitemia in a mouse model of malaria, decreased liver and spleen pathology and reduced parasite tr...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-018-27073-1

    authors： Glennon EKK,Megawati D,Torrevillas BK,Ssewanyana I,Huang L,Aweeka F,Greenhouse B,Adams LG,Luckhart S

    更新日期：2018-06-11 00:00:00

  • Novel instrumented frame for standing exercising of users with complete spinal cord injuries.

    abstract：:This paper describes a Functional Electrical Stimulation (FES) standing system for rehabilitation of bone mineral density (BMD) in people with Spinal Cord Injury (SCI). BMD recovery offers an increased quality of life for people with SCI by reducing their risk of fractures. The standing system developed comprises an i...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-019-49237-3

    authors： Zoulias ID,Armengol M,Poulton A,Andrews B,Gibbons R,Harwin WS,Holderbaum W

    更新日期：2019-09-10 00:00:00

  • Whole Mitogenomes Reveal the History of Swamp Buffalo: Initially Shaped by Glacial Periods and Eventually Modelled by Domestication.

    abstract：:The newly sequenced mitochondrial genomes of 107 Asian swamp buffalo (Bubalus bubalis carabensis) allowed the reconstruction of the matrilineal divergence since ~900 Kya. Phylogenetic trees and Bayesian skyline plots suggest a role of the glacial periods in the demographic history of swamp buffalo. The ancestral swamp...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-017-04830-2

    authors： Wang S,Chen N,Capodiferro MR,Zhang T,Lancioni H,Zhang H,Miao Y,Chanthakhoun V,Wanapat M,Yindee M,Zhang Y,Lu H,Caporali L,Dang R,Huang Y,Lan X,Plath M,Chen H,Lenstra JA,Achilli A,Lei C

    更新日期：2017-07-05 00:00:00

  • Unique IL-13Rα2/STAT3 mediated IL-13 regulation detected in lung conventional dendritic cells, 24 h post viral vector vaccination.

    abstract：:This study demonstrates that 24 h following viral vector-based vaccination IL-13Rα2 functions as a master sensor on conventional dendritic cells (cDCs), abetted by high protein stability coupled with minimal mRNA expression, to rapidly regulate DC mediated IL-13 responses at the lung mucosae, unlike IL-13Rα1. Under lo...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-020-57815-z

    authors： Roy S,Liu HY,Jaeson MI,Deimel LP,Ranasinghe C

    更新日期：2020-01-23 00:00:00

  • Network analysis reveals why Xylella fastidiosa will persist in Europe.

    abstract：:The insect vector borne bacterium Xylella fastidiosa was first detected in olive trees in Southern Italy in 2013, and identified as the main culprit behind the 'olive quick decline syndrome'. Since then, the disease has spread rapidly through Italy's main olive oil producing region. The epidemiology of the outbreak is...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-017-00077-z

    authors： Strona G,Carstens CJ,Beck PS

    更新日期：2017-03-06 00:00:00

  • Regulation of global gene expression and cell proliferation by APP.

    abstract：:Down syndrome (DS), caused by trisomy of chromosome 21, is one of the most common genetic disorders. Patients with DS display growth retardation and inevitably develop characteristic Alzheimer's disease (AD) neuropathology, including neurofibrillary tangles and neuritic plaques. The expression of amyloid precursor pro...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/srep22460

    authors： Wu Y,Zhang S,Xu Q,Zou H,Zhou W,Cai F,Li T,Song W

    更新日期：2016-03-03 00:00:00

  • The Andaman day gecko paradox: an ancient endemic without pronounced phylogeographic structure.

    abstract：:The Andaman day gecko (Phelsuma andamanensis) is endemic to the Andaman Archipelago, located ~ 6000 km away from Madagascar where the genus Phelsuma likely evolved. We complemented existing phylogenetic data with additional markers to show that this species consistently branches off early in the evolution of the genus...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-020-68402-7

    authors： Mohan AV,Orozco-terWengel P,Shanker K,Vences M

    更新日期：2020-07-16 00:00:00

  • Damnacanthal, a noni anthraquinone, inhibits c-Met and is a potent antitumor compound against Hep G2 human hepatocellular carcinoma cells.

    abstract：:Damnacanthal, an anthraquinone present in noni plants, targets several tyrosine kinases and has antitumoral effects. This study aims at getting additional insight on the potential of damnacanthal as a natural antitumor compound. The direct effect of damnacanthal on c-Met was tested by in vitro activity assays. Additio...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/srep08021

    authors： García-Vilas JA,Quesada AR,Medina MA

    更新日期：2015-01-26 00:00:00

  • MicroRNA-155 is upregulated in ascites in patients with spontaneous bacterial peritonitis.

    abstract：:MircoRNA's (miR) have been recognised as important modulators of gene expression and potential biomarkers. However, they have been rarely investigated in bio fluids apart from blood. We investigated the association of miR-125b and miR-155 with complications of cirrhosis. Ascites was prospectively collected from patien...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/srep40556

    authors： Lutz P,M Haimid M,Pohlmann A,Lehmann J,Jansen C,Schierwagen R,Klein S,Strassburg CP,Spengler U,Trebicka J

    更新日期：2017-01-11 00:00:00

  • An integrative approach to phylogeny reveals patterns of environmental distribution and novel evolutionary relationships in a major group of ciliates.

    abstract：:Peritrichs are a major group of ciliates with worldwide distribution. Yet, its internal phylogeny remains unresolved owing to limited sampling. Additionally, ecological distributions of peritrichs are poorly known. We performed substantially expanded phylogenetic analyses of peritrichs that incorporated SSU rDNA seque...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/srep21695

    authors： Sun P,Clamp J,Xu D,Huang B,Shin MK

    更新日期：2016-02-16 00:00:00