Biological treatment of the knee with platelet-rich plasma or bone marrow aspirate concentrates.

Abstract:

:- Knee pathologies including focal cartilage injuries, osteoarthritis (OA), and ligament injuries are common. The poor regeneration and healing potential of cartilage has led to the search for other treatment modalities with improved healing capacity. Furthermore, with an increasing elderly population that desires to remain active, the burden of knee pathologies is expected to increase. Increased sports participation and the desire to return to activities faster is also demanding more effective and minimally invasive treatment options. Thus, the use of biologic agents in the treatment of knee pathologies has emerged as a potential option. Despite the increasing use of biologic agents for knee pathology, there are conflicting results on the efficacy of these products. Furthermore, strong data supporting the optimal preparation methods and composition for widely used biologic agents, such as platelet-rich plasma (PRP) and bone marrow aspirate concentrate (BMAC), largely remain absent from the literature. This review presents the literature on the most commonly employed biologic agents for the different knee pathologies.

journal_name

Acta Orthop

journal_title

Acta orthopaedica

authors

Moatshe G,Morris ER,Cinque ME,Pascual-Garrido C,Chahla J,Engebretsen L,Laprade RF

doi

10.1080/17453674.2017.1368899

subject

Has Abstract

pub_date

2017-12-01 00:00:00

pages

670-674

issue

6

eissn

1745-3674

issn

1745-3682

journal_volume

88

pub_type

杂志文章,评审