Commentary on Some Recent Theses Relevant to Combating Aging: August 2017.

abstract：:No study has yet determined the anti-wrinkle efficacy of green tea plus lotus in Asian subjects using skin image analysis technique. In this study, the efficacy of two cosmetic active formulations intended for the treatment of facial wrinkles (green tea and lotus extract) has been evaluated in healthy subjects using a...

journal_title：Rejuvenation research

authors： Mahmood T,Akhtar N

更新日期：2013-04-01 00:00:00

abstract：:Decades of studies of candidate genes show their complex role in aging-related traits. We focus on apolipoprotein E e2/3/4 polymorphism and ages at onset of cardiovascular diseases (CVD) and cancer in the parental and offspring generations of the Framingham Heart Study participants to gain insights on the role of age ...

journal_title：Rejuvenation research

authors： Kulminski AM,Culminskaya I,Arbeev KG,Ukraintseva SV,Arbeeva L,Yashin AI

更新日期：2013-02-01 00:00:00

abstract：:The United States has the most expensive healthcare system worldwide. Yet measures of health span and life expectancy are well below the major industrialized nations. With the U.S. population aged 65 years and older projected to double by mid-century, a healthcare crisis is looming. Within this context, huge interest ...

journal_title：Rejuvenation research

authors： Larrick JW,Mendelsohn AR

更新日期：2018-06-01 00:00:00

abstract：:Twenty years have passed since Kadenbach and Müller-Höcker first proposed that the age-related accumulation of mutant mitochondrial DNA is caused by its clonal expansion, rather than by a "vicious cycle" of de novo mutational events caused by the disruptive metabolic impact of prior ones. Proof that they were correct ...

journal_title：Rejuvenation research

authors： de Grey AD

更新日期：2009-06-01 00:00:00

abstract：:This study aimed at comparing the effects of three chair-based exercise programs on people older than 80 years. Thirty-six participants (87.91 ± 4.70 years) were randomly allocated to an aerobic, muscular resistance, or joint mobility exercise program. The participants exercised 3 days per week during 3 months. A hand...

journal_title：Rejuvenation research

authors： Cancela Carral JM,Pallin E,Orbegozo A,Ayán Pérez C

更新日期：2017-10-01 00:00:00

abstract：:It is known that weakness in the lower limbs is associated with recurrent falls in old people. Among the tests routinely used to assess lower extremity strength, the Short Physical Performance Battery (SPPB) is one of those used most often, but its relationship with recurrent falls is poorly investigated. We aimed to ...

journal_title：Rejuvenation research

authors： Veronese N,Bolzetta F,Toffanello ED,Zambon S,De Rui M,Perissinotto E,Coin A,Corti MC,Baggio G,Crepaldi G,Sergi G,Manzato E

更新日期：2014-06-01 00:00:00

abstract：:A hypothetical mechanism of 14C-generated influence on a person's rate of aging is offered. The mathematical description and the following approbation of the radiocarbon mechanism of aging made it possible to coordinate the Gompertz and Strehler-Mildvan laws and predict the existence of one more, till-now unknown, int...

journal_title：Rejuvenation research

authors： Germansky AM,Germanskaia AA

更新日期：2006-07-01 00:00:00

abstract：:Osteoarthritis is the most common disabling condition of humans in the western world. It has been known for a very long time that aging is the most prominent risk factor for the initiation and progression of the disease, but the explanations for this phenomenon have changed over time. The most longstanding theory is t...

journal_title：Rejuvenation research

authors： Aigner T,Rose J,Martin J,Buckwalter J

更新日期：2004-07-01 00:00:00

abstract：:The aim of the current study was to develop fitness standards associated with maintaining physical capacity in older adults at two different levels-that needed for advanced functioning and that needed for maintaining moderate (independent) functional ability. This was a cross-sectional study of 406 Chilean adults aged...

journal_title：Rejuvenation research

authors： Merellano-Navarro E,Collado-Mateo D,García-Rubio J,Gusi N,Olivares PR

更新日期：2017-12-01 00:00:00

abstract：:The 2013 Rostock Symposium on Systems Biology and Bioinformatics in Aging Research was again dedicated to dissecting the aging process using in silico means. A particular focus was on ontologies, because these are a key technology to systematically integrate heterogeneous information about the aging process. Related t...

journal_title：Rejuvenation research

authors： Fuellen G,Boerries M,Busch H,de Grey A,Hahn U,Hiller T,Hoeflich A,Jansen L,Janssens GE,Kaleta C,Meinema AC,Schäuble S,Simm A,Schofield PN,Smith B,Sühnel J,Vera J,Wagner W,Wönne EC,Wuttke D

更新日期：2013-12-01 00:00:00

abstract：:Our recent studies have shown that Huogu (HG) formula was effective both in clinic experience and in experimental osteonecrosis of the femoral head (ONFH). Given that defective of bone marrow stromal cells (MSCs) contribute to the development of osteonecrosis and MSCs show enormous potential in the treatment of ONFH, ...

journal_title：Rejuvenation research

authors： Kong X,Li X,Zhang C,Zhu L,Wan H,Zhu J,Liu C,Su H,Qin Q,Chen W,Lin N

更新日期：2016-12-01 00:00:00

abstract：:Thrombolytic therapy (TT) is applied in patients (<75 years of age) with acute myocardial infarction (AMI) with ST-segment elevation. It is recommended for elderly patients who have percutaneous transluminal coronary angioplasty (PTCA) or bypass surgery. For PTCA and bypass surgery a cardiosurgery medical team, which ...

journal_title：Rejuvenation research

authors： Taneva E

更新日期：2006-07-01 00:00:00

abstract：:The relationships among lipoprotein metabolism, genetic vascular factors, vascular disease, and Alzheimer's disease suggest that the examination of centenarian populations in relation to certain genes or lipoprotein metabolism provide insights into human longevity. The findings on the higher frequency of the apolipopr...

journal_title：Rejuvenation research

authors： Panza F,D'introno A,Capurso C,Colacicco AM,Seripa D,Pilotto A,Santamato A,Capurso A,Solfrizzi V

更新日期：2007-12-01 00:00:00

abstract：:Theses reviewed in this issue include "Characterization and Purification of Putative Stem Cells from the Adult Murine Pancreas," "Inhibition of TLR4 Minimizes Islet Damage due to Sterile Inflammation and Improves Islet Transplant Outcomes," "Liquefaction of the Brain Following Stroke Shares Multiple Characteristics wi...

journal_title：Rejuvenation research

authors： Zealley B,de Grey ADNJ

更新日期：2020-08-01 00:00:00

abstract：:We tried to establish an age-predictive equation from kinematic and kinetic parameters during walking using the 2007 Okada database of Japanese elderly. Some predictive equations were established for each gender (109 males and 139 females)--once for all variables, second for the stepwise variable selection method. The...

journal_title：Rejuvenation research

authors： Kikkawa K,Okada H,Mori T

更新日期：2010-04-01 00:00:00

abstract：:d-galactose (d-gal) is widely used to induce aging. However, it is still unclear whether long-term injection of d-gal affects the gastrointestinal functions of aging rats, and how. In this study, we investigated the effects of d-gal on the gastrointestinal functions of aging rats, especially from the perspective of fe...

journal_title：Rejuvenation research

authors： Zhao D,Liu X,Zhao S,Li Z,Qin X

更新日期：2020-09-29 00:00:00

abstract：:Osteoporosis is a silent disease caused by low bone mineral density and is complicated by fractures. This study was designed to examine the differentiation of uterine stem cell-derived osteoprogenitor cells (UOPCs) both in vitro and in vivo, assessing their effectiveness in treating osteoporosis. CD271+/CD45- UOPCs we...

journal_title：Rejuvenation research

authors： Wang Z,Wang D,Liu Y,Liu D,Ren Y,Liu Z,Yu B,Hao M,Xie J

更新日期：2020-11-03 00:00:00

abstract：:In otherwise healthy adults, moderate aerobic exercise extends life span and likely health span by 2-6 years. Exercise improves blood sugar regulation, and resistance exercise increases or maintains muscle mass and is associated with improved cognitive function. On the other hand, evidence for anti-oxidant supplements...

journal_title：Rejuvenation research

authors： Mendelsohn AR,Larrick JW

更新日期：2013-10-01 00:00:00

abstract：:New avenues to modulate the autophagy-lysosomal route of protein clearance have the potential to help treat several disease states to which the elderly are particularly vulnerable. Two recent papers identified distinct ways to tap into the lysosomal degradation pathway of autophagy to reduce age-related protein accumu...

journal_title：Rejuvenation research

authors： Bahr BA

更新日期：2014-08-01 00:00:00

abstract：:Abnormalities of gene structure or expression are commonly found in cancers, where they are used as prognostic markers, predicting the likely severity of disease or chances of response to therapy. An odds ratio (OR) of <1 indicates that a marker's presence is correlated with better outcome. An OR of <1 is also often t...

journal_title：Rejuvenation research

authors： Bains W

更新日期：2004-10-01 00:00:00

abstract：:Availability of reliable prognostic biomarkers that are also able to monitor preventive/therapeutic interventions in patients with mild cognitive impairment (MCI) is crucial. Cerebral brain-derived neurotrophic factor (BDNF) alterations were evidenced in Alzheimer's disease, but the value of blood BDNF in MCI is uncle...

journal_title：Rejuvenation research

authors： Balietti M,Giuli C,Casoli T,Fabbietti P,Conti F

更新日期：2020-10-01 00:00:00

abstract：:The progeroid Werner's syndrome (WS) represents the best current model of human aging. It is caused by loss of the WRN helicase/exonuclease, resulting in high levels of replication fork stalling and genomic instability. Current models suggest that characteristic WS phenotypes of poor S phase progression, low prolifera...

journal_title：Rejuvenation research

authors： Rodriguez-Lopez AM,Whitby MC,Borer CM,Bachler MA,Cox LS

更新日期：2007-03-01 00:00:00

abstract：:The aim of this study was to evaluate the role of magnesium levels on 3-year survival in the elderly with congestive heart failure (CHF) admitted to the Rehabilitative Cardiology Unit of S. Maugeri Foundation Scientific Institute of Telese/Campoli. All elderly patients > or = 65 years old with a diagnosis of CHF under...

journal_title：Rejuvenation research

authors： Corbi G,Acanfora D,Iannuzzi GL,Longobardi G,Cacciatore F,Furgi G,Filippelli A,Rengo G,Leosco D,Ferrara N

更新日期：2008-02-01 00:00:00

abstract：:The emergence of immune disorders in aging is explained by many factors, including thymus dysfunction, decrease in the proportion and function of naïve T cells, and so forth. There are several approaches to preventing these changes, such as thymus rejuvenation, stem cells recovery, modulation of hormone production, an...

journal_title：Rejuvenation research

authors： Pishel I,Shytikov D,Orlova T,Peregudov A,Artyuhov I,Butenko G

更新日期：2012-04-01 00:00:00

abstract：:Inflammation is a key component of immune system. It is involved in both defense and pathophysiological events maintaining the dynamic homeostasis of host organism. Its function is controlled by innate immunity genes. Both their polymorphisms and environmental conditions give rise to different phenotypes in human popu...

journal_title：Rejuvenation research

authors： Balistreri CR,Candore G,Mirabile M,Lio D,Caimi G,Incalcaterra E,Caruso M,Hoffmann E,Caruso C

更新日期：2008-04-01 00:00:00

abstract：:Physical exercise is a potential intervention to revert or attenuate frailty syndrome, which may be accomplished by traditional center-based and home-based programs. This study aimed to compare the effectiveness of a home-based and center-based exercise program on frailty status, physical and muscle function of frail ...

journal_title：Rejuvenation research

authors： Garcia RNSA,Costa SN,Garcia EDSA,Bento PCB

更新日期：2020-05-26 00:00:00

abstract：:To evaluate a possible involvement of the brain-derived neurotrophic factor (BDNF) Val66Met polymorphism in susceptibility to Parkinson's disease (PD), we performed a meta-analysis of all studies on the topic published from 2002 to 2014. This article reviews and compares the data from two previous meta-analyses, inclu...

journal_title：Rejuvenation research

authors： Mariani S,Ventriglia M,Simonelli I,Bucossi S,Siotto M,R RS

更新日期：2015-02-01 00:00:00

abstract：:Pursuance of longevity is not only combating decrepitude but it is also extending the health span; otherwise longevity would result in a universal medical and social burden. As revealed by the literature, the attainment of a healthy life could be impacted by the social milieu. An inquiry of this kind could hardly be s...

journal_title：Rejuvenation research

authors： Lai WF,Chan ZC

更新日期：2011-02-01 00:00:00

abstract：:The human mitochondrion contains a small circular genome that codes for 13 proteins, 22 tRNAs, and 2 rRNAs. The proteins are all inner membrane bound components of complexes involved in the electron transport system and ATP formation. Mutations to any of the 13 proteins affect cellular behavior because energy producti...

journal_title：Rejuvenation research

authors： Mukhopadhyay A,Zullo SJ,Weiner H

更新日期：2006-07-01 00:00:00

abstract：:The notion that it is possible to eradicate age-related degeneration and live a life with a negligible rate of senescence solely by using a physical "repair-oriented" approach is flawed on a number of fronts. Here, I will argue that there are so many unknown variables embedded in this line of thinking that make the fi...

journal_title：Rejuvenation research

authors： Kyriazis M

更新日期：2014-08-01 00:00:00