Abstract：
BACKGROUND:The objective was to estimate the incidence of asthma in young adults from 13-15 years old to 23-25 years old, and associated factors. METHODS:In 2012, a population-based prospective cohort study was carried out in Castellon from the cohort who had participated in the International Study of Asthma and Allergy in Childhood in 1994 and 2002. A telephone survey was undertaken using the same questionnaires. A new case of asthma was defined as a participant free of the disease in 2002 who suffered asthma, was diagnosed with asthma, or took medications against asthma based on self-report from 2002 to 2012. RESULTS:The mean age of participants was 24.9±0.6 with a follow-up of 79.1%. Asthma cumulative incidence was 3.4%: 44 new cases occurred among 1280 participants. The incidence was higher in females than males with relative risk (RR)=2.02 (95% confidence interval [CI] 1.1-3.8). A significant decrease of asthma incidence density was observed (8.2 cases to 3.5 cases per 1000 person/year). Factors associated with the incidence of asthma were allergic rhinitis (RR=4.05; 95% CI 1.7-9.6), bronchitis (RR=2.13; 95% CI 1.0-4.5), mother's age at time of birth (RR=0.87; 95% CI 0.8-0.9) and a pet other than a dog or cat (RR=0.42; 95% CI 0.2-0.9). For gender, some variations in the risk factors were observed. CONCLUSIONS:A significant decrease in the incidence of asthma was observed. Several risk and protective factors were found.
journal_name
Allergol Immunopathol (Madr)journal_title
Allergologia et immunopathologiaauthors
Segura-Navas L,Arnedo-Pena A,Tosca-Segura R,Romeu-García MA,Meseguer-Ferrer N,Silvestre-Silvestre E,Conde F,Fernández-González S,Dubon M,Ortuño-Forcada M,Fabregat-Puerto J,Fenollosa-Amposta C,Pac-Sa MR,Museros-Recatala L,Vizcdoi
10.1016/j.aller.2017.03.003subject
Has Abstractpub_date
2018-01-01 00:00:00pages
112-118issue
2eissn
0301-0546issn
1578-1267pii
S0301-0546(17)30069-1journal_volume
46pub_type
杂志文章abstract：UNLABELLED:Asthma is one of the most frequent chronic illnesses in paediatric age children. In the last reviews carried out by the group of experts (EPR II) in 1997, a chapter was included on education for the groups who are involved with looking after patients with asthma, and proposes the inclusion of questions focus...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章,多中心研究
doi：
更新日期：2000-05-01 00:00:00
abstract：BACKGROUND:Although it has been hypothesized that infections may play a preventive role in allergic diseases, the role of Helicobacter pylori (H. pylori) is not clear. In this study we aimed to determine the association between H. pylori infection and allergic inflammation. METHODS:H. pylori infection was assessed in ...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：10.1157/13120393
更新日期：2008-03-01 00:00:00
abstract：:The etiological importance of the dietary factor as related to infantile bronchial asthma is not, at times, sufficiently taken into consideration. Nevertheless, many times foods or their components are capable of provoking asthmatic symptoms. A group of asthmatic children was studied with the goal of more throughly co...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：
更新日期：1980-01-01 00:00:00
abstract：INTRODUCTION AND OBJECTIVES:Despite the recommendation against routine use of inhaled bronchodilators in infants with viral bronchiolitis given in the main clinical practice guidelines (CPGs) on viral bronchiolitis, albuterol is widely prescribed to patients with this disease. The aim of this study was to identify pred...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：10.1016/j.aller.2019.10.007
更新日期：2020-01-01 00:00:00
abstract：:A procedure is described for the cytochemical detection of esterase alpha naphtyl acetate (ANAE) and beta glucuronidase (BG) activity in the circulating lymphocytes of man. The number of BG positive cells (TBG) as evaluated on the smears of Ficoll Urovision purified cells, correlated well with the number of T gamma (E...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：
更新日期：1982-03-01 00:00:00
abstract：:We report the case of a 42-year-old non-smoking man, who had worked as a carpenter for 6 years and who reported a history of rhinorrhea, paroxysmal sneezing, nasocular pruritus, lacrimation, wheezing and dyspnea attacks while preparing a mixture to seal the junctures between wooden panels. Allergy study consisted of s...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：10.1016/s0301-0546(05)73251-1
更新日期：2005-11-01 00:00:00
abstract：BACKGROUND:It is thought that airway inflammation is more common in obese asthmatic patients because inflammation is harder to control and does not respond well to glucocorticoid treatment. OBJECTIVE:This study's aim was to investigate the effect of obesity on airway and systemic inflammation in children with asthma a...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：10.1016/j.aller.2017.01.013
更新日期：2017-01-01 00:00:00
abstract：BACKGROUND:Few previous reports of carrot-induced asthma have been confirmed by objective tests. Hypersensitivity to carrot is frequently associated with allergy to Apiaceae spices and sensitization to birch and mugwort pollens. CLINICAL CASE:A 40-year-old cook woman was seen with sneezing, rhinorrhea, contact urticar...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：10.1157/13080934
更新日期：2005-09-01 00:00:00
abstract：:In a previous study we had found a high correlation between the positive reaction to standard house dust and to a mites pool extract of 0.86. The study had indicated that the dominant mite found in standard house dust in Barcelona seemed to be D. pteronyssinus. We wished to further confirm this finding by comparing sk...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：
更新日期：1976-01-01 00:00:00
abstract：:The mechanisms of action of prophylactic antiallergic drugs, especially disodium cromoglycate (DSCG), have been reviewed. Some evidence is presented that suggests that DSCG acts not only as an inhibitor of mediator release from mast cells, but also by inhibiting the effects of mediators on bronchial and intestinal smo...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章,评审
doi：
更新日期：1981-11-01 00:00:00
abstract：BACKGROUND:Despite growing evidence suggesting potential association between innate and adaptive immunity in viral-induced acute asthma, there is paucity of data in this area. OBJECTIVE:This study aimed to investigate the association of innate and adaptive immunity with acute asthma attacks by analysing the role of IF...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：10.1016/j.aller.2016.07.003
更新日期：2017-01-01 00:00:00
abstract：:Thanks to its excellent safety profile, sublingual immunotherapy has served as a basis for launching two important lines of research in current allergology: sublingual immunotherapy with pharmaceutical registry (oral lyophilizates or tablets), and sublingual immunotherapy with food. At present, clinical trials are bei...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：10.1016/s0301-0546(08)75223-6
更新日期：2008-09-01 00:00:00
abstract：:Lumry described 6 patients who presented hypertrophic rhinosinusitis, positive nasal eosinophilia and intolerance to nonsteroidal antiinflammatory drugs, manifested exclusively with naso-ocular symptomatology. We present three patients with clinical manifestations of chronic rhinitis who had noticed before their first...
journal_title：Allergologia et immunopathologia
pub_type： 临床试验,杂志文章
doi：
更新日期：1986-03-01 00:00:00
abstract：:Perioperative anaphylactic reactions are immediate, hypersensitive reactions that are potentially life-threatening resulting from a sudden release of mediators from mast cells and basophiles, due to either immune (IgE or non-IgE mediated) or non-immune mechanisms. The most frequent causing agents are neuromuscular blo...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章,评审
doi：10.1016/j.aller.2013.07.012
更新日期：2015-03-01 00:00:00
abstract：:Thirty-four patients suffering from rhinoconjunctivitis with or without asthma due to grass pollen, were submitted to sublingual immunotherapy according to a double blind placebo controlled experimental plan; eighteen patients received the active therapy, sixteen the placebo. A rush preseasonal treatment schedule was ...
journal_title：Allergologia et immunopathologia
pub_type： 临床试验,杂志文章,多中心研究
doi：
更新日期：1995-09-01 00:00:00
abstract：:The proliferative and stimulatory capacities in allogeneic and autologous mixed lymphocyte reactions were evaluated in 5 patients affected by renal insufficiency undergoing maintenance hemodialysis. The expression of HLA class II antigens and Interleukin 2 production by PHA-activated T cells were also investigated. Fu...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：
更新日期：1991-07-01 00:00:00
abstract：:We present the clinical case of a 8-years-old boy suffering a fixed drug reaction attributed to the oral intake of loratadine. He is an atopic child with perennial rhinitis and asthma and marked hypersensitivity to the house-dust mite Dermatophagoides pteronyssinus who is receiving inhaled corticosteroids and b2-agoni...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：10.1016/s0301-0546(03)79199-x
更新日期：2003-09-01 00:00:00
abstract：BACKGROUND:Pseudo-allergic reactions against aspirin (ASA) and non-steroidal anti-inflammatory drugs (NSAIDs) are quite frequent. OBJECTIVE:Our aim was to determine tolerance of Celecoxib, a selective inhibitor of cyclooxygenase-2 (Cox-2), by oral challenge test in patients who showed skin reactions (diffuse erythema ...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：10.1157/13108222
更新日期：2007-07-01 00:00:00
abstract：BACKGROUND:Food allergy can have a major impact on quality of life of children and their parents. Questionnaires have been developed to measure the impact of this disorder. We aimed to validate the EuroPrevall questionnaire on Food Allergy-Quality of Life Questionnaire, Parent Form (FAQLQ-PF) and the Food Allergy Indep...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：10.1016/j.aller.2017.06.004
更新日期：2018-01-01 00:00:00
abstract：BACKGROUND:Cloxacillin is a semisynthetic penicillin widely used in nonmethicillin resistant Staphylococcus aureus infections. Several hypersensitivity reactions to cloxacillin have been reported, although IgE-mediated allergic reactions to the drug are rare and there is little information about possible tolerance to o...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：10.1157/13084226
更新日期：2006-01-01 00:00:00
abstract：:Atopic dermatitis (AD) is a multifaceted disease that involves a complex interplay between the skin and the immune system. The course of the disease depends strongly on the genetic background of the patient and on yet poorly-defined environmental factors. Changes in lifestyle could be behind the dramatic rise in the p...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章,评审
doi：10.1016/j.aller.2017.07.002
更新日期：2018-01-01 00:00:00
abstract：OBJECTIVE:To determine the accuracy of the peak expiratory flow (PEF) as an alternative parameter to the forced expiratory volume at first second (FEV1) in the bronchodynamic tests. METHODOLOGY:We studied 84 patients, 53 males and 31 females, with average age 46 +/- 13 years, as clinic suspects of bronchial asthma. PE...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：
更新日期：1996-03-01 00:00:00
abstract：:The present prospective, open, observational study assessed the effect of the use of standard environmental control measures together with the application of an acaricide-containing aerosol of esbiol/benzyl benzoate/piperonyl butoxide/2-phenylphenol (Frontac) on several clinical and environmental parameters in patient...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章,多中心研究
doi：10.1016/s0301-0546(02)79096-4
更新日期：2002-03-01 00:00:00
abstract：OBJECTIVES:To characterize the most frequently found radiological findings in intestinal anisakiasis. MATERIAL AND METHODS:The medical records of 14 patients diagnosed with intestinal anisakiasis between 2000 and 2003 in the Hospital Clinico Universitario Lozano Blesa in Zaragoza (Spain) were retrospectively reviewed....
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章,评审
doi：10.1157/13070605
更新日期：2005-01-01 00:00:00
abstract：:The term food allergy refers to the immune reaction (mediated by IgE or otherwise) that develops in response to the ingestion of a concrete type of food. Among the different potential manifestations of an allergic reaction, those exclusively affecting the gastrointestinal system are described. In recent years, the stu...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章,评审
doi：10.1016/s0301-0546(09)70250-2
更新日期：2009-01-01 00:00:00
abstract：:For one year dust was sampled monthly from a single mattress. Until August mite counts were at background levels. In September and October there was a burst in the counts for the house-dust mite, Dermatophagoides farinae and for the house mite, Glycyphagus domesticus. Their occurrence might be interpreted as a respons...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：
更新日期：1983-05-01 00:00:00
abstract：:Specific immunotherapy consists of the administration of allergen extracts to patients with allergic disease to achieve clinical tolerance to the causative allergens. Currently, it is the only etiologic treatment for respiratory allergy. A World Health Organization opinion paper published in 1997 defines immunotherapy...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章,评审
doi：10.1016/s0301-0546(04)79300-3
更新日期：2004-05-01 00:00:00
abstract：OBJECTIVE:This study aimed to assess the regular use of long-term asthma-control medication and to determine inhaler techniques in asthmatic children. METHODS:The study was conducted on asthmatic children aged 6-18 years. Information on rescue and controller medications was given and the proper inhalation technique wa...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：10.1016/j.aller.2019.06.009
更新日期：2020-01-01 00:00:00
abstract：:Some authors succeded in binding the bradykinin in form of a haptene by an azo-bridge to the human gammaglobulin as a vehicle. In this way, the bradykinin has been supplemented to a complete antigen. The bradykinin as a strongly vasoactive substance causes--after a local intradermal injection--an intensive circumscrib...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：
更新日期：1977-03-01 00:00:00
abstract：:Serum zinc, copper and iron levels together with content of zinc in hair were investigated in 13 patients with common variable immunodeficiency (CVID) and in 13 controls. A significant decrease in serum zinc (mean = 11.3 mumol/l, SD = 2.9 in CVID patients compared to mean 14.3 mumol/l, SD = 2.4 in controls) and iron l...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：
更新日期：1995-05-01 00:00:00
