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Focal lesions in cirrhosis: Not always HCC.

Abstract：

:Even though most hepatocellular carcinomas (HCC) develop in the setting of cirrhosis, numerous other focal liver lesions and pseudolesions may be encountered. The role of the radiologist is therefore to differentiate these lesions from HCC to avoid under- and overdiagnosis. There are several ways of classifying these lesions: those which predate the development of fibrosis and cirrhosis (cystic lesions, hemangioma), those related to or a consequence of cirrhosis (regenerative nodules, dysplastic nodules, focal fibrosis, peribiliary cysts, shunts, or even cholangiocarcinoma), and those related to the underlying cause of chronic liver disease (lymphoma). Finally, some may develop independently (liver metastases). From an imaging point of view, it is important to remember that the imaging features of pre-existing lesions are not dramatically changed by cirrhosis. Differentiating non-HCC from HCC requires not only an understanding of the multi-step process of hepatocarcinogenesis, but also the importance of medical history, and of complimentary imaging modalities, namely computed tomography (CT) and magnetic resonance imaging (MRI). This review article gives an overview of the imaging features of benign and malignant non-HCC focal liver lesions in the setting of cirrhosis, with a focus on CT and MR imaging.

journal_name

Eur J Radiol

journal_title

European journal of radiology

authors

Ronot M,Dioguardi Burgio M,Purcell Y,Pommier R,Brancatelli G,Vilgrain V

doi

10.1016/j.ejrad.2017.05.040

subject

Has Abstract

pub_date

2017-08-01 00:00:00

pages

157-168

eissn

0720-048X

issn

1872-7727

pii

S0720-048X(17)30219-X

journal_volume

93

pub_type

杂志文章,评审

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