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Lupus mastitis as a first manifestation of systemic disease: About two cases with a review of the literature.

Abstract：

:Lupus mastitis is an uncommon manifestation of systemic lupus erythematosus (SLE) that affects the subcutaneous fat in the breast, much like lupus panniculitis, but additionally involves the mammary gland. We report on two women for whom lupus mastitis was the initial manifestation of SLE and provide a literature review of 34 additional cases reported in the Anglo-Saxon and French literature since 1971, making this the largest review to date. Lupus mastitis (LM) can manifest clinically as subcutaneous masses that may be painful, or may present cutaneous involvement such as thickening and discolouration. The radiologic manifestations of LM are broad and include calcifications, masses and asymmetries. Most often, excluding malignancy requires percutaneous biopsy, with histologic findings that are virtually pathognomonic for SLE. Thus, surgery is avoided and medical management can begin, antimalarial drugs and corticosteroids in most cases.

journal_name

Eur J Radiol

journal_title

European journal of radiology

authors

Voizard B,Lalonde L,Sanchez LM,Richard-Chesnay J,David J,Labelle M,El Khoury M,Trop I

doi

10.1016/j.ejrad.2017.04.023

subject

Has Abstract

pub_date

2017-07-01 00:00:00

pages

124-131

eissn

0720-048X

issn

1872-7727

pii

S0720-048X(17)30171-7

journal_volume

92

pub_type

杂志文章,评审

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