Abstract:
PURPOSE:To evaluate retrospectively the prognostic significance of lymph node parameters assessed on pretreatment magnetic resonance (MR) images for development of distant metastases in patients with head and neck squamous cell carcinomas. MATERIALS AND METHODS:Pretreatment MR images of 311 patients were retrospectively reviewed for the presence of lymph nodes at specific neck node levels as well as the size and the presence of a number of lymph node characteristics including extranodal spread, central necrosis and number and volume of ipsi- and contralateral nodes. Of these patients, 174 (56%) had MRI-positive nodes (defined as nodes with minimum axial diameter >8 and >4 mm for paratracheal level and retropharyngeal nodes). RESULTS:The 2-year distant-metastasis free survival rate (DMFSR) for patients without MRI-positive nodes was 94% compared to 75% for those patients with MRI-positive nodes. In patients with MRI-positive nodes, results of multivariate analysis with the Cox regression model yielded statistical significance for presence of extranodal spread (ENS), detected on MRI, as the only independent prognostic factor associated with the 2-year DMFSR (p=0.002). Based on the analysis, three risk groups regarding the DMFSR could be identified. Low-risk group (DMFSR:94%) consisted of patients without MRI-positive nodes. Intermediate-risk group (DMFSR:81%) consisted of patients with MRI-positive nodes without ENS. High-risk group (DMFSR:59%) consisted of patients with MRI-positive nodes and ENS as shown on MRI (p<0.0001). Statistical separation for different tumor locations showed MRI-determined ENS (larynx: p=0.05; oropharynx: p=0.04; oral cavity: p<0.001), lowjugular/posterior triangle nodes (oropharynx: p=0.02), paratracheal nodes (larynx: p=0.03), and contralateral node volume >5 cm3 (larynx: p=0.03; oral cavity: p=0.02) to be significant predictors with regard to DMFSR. CONCLUSION:Especially patients with on MRI demonstrating extranodal spread and with suspicious nodes at lowjugular/posterior triangle (oropharyngeal cancer) or paratracheal level (laryngeal cancer), or with contralateral enlarged nodes (laryngeal and oral cavity cancer) are at high risk for developing distant metastases and this subset of patients might benefit from supplementary imaging screening (CT-chest, PET-scan).
journal_name
Eur J Radioljournal_title
European journal of radiologyauthors
Ljumanovic R,Langendijk JA,Hoekstra OS,Leemans CR,Castelijns JAdoi
10.1016/j.ejrad.2006.05.019subject
Has Abstractpub_date
2006-10-01 00:00:00pages
58-66issue
1eissn
0720-048Xissn
1872-7727pii
S0720-048X(06)00217-8journal_volume
60pub_type
杂志文章abstract:PURPOSE:To test a single-energy low-voltage CT protocol for pancreatic adenocarcinoma. METHODS AND MATERIALS:A total of 30 patients with pathology-proven pancreatic adenocarcinoma underwent 64-row MDCT with arterial phase at 80 kV and were compared to a similar group of 30 patients scanned with a 120 kV protocol. Scan...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2013.12.022
更新日期:2014-03-01 00:00:00
abstract:OBJECTIVE:Various degrees of aortic valve rotation may be seen in individuals with no history of congenital cardiovascular malformations, but its association with aortic sizes has not been studied. METHODS:Gated computed tomographic (CT angiograms in 217 patients were studied (66.7±15; 22-97 years old)). Aortic diamet...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2017.01.009
更新日期:2017-04-01 00:00:00
abstract:PURPOSE:To investigate the value of third-generation dual-source dual-energy computed tomography (DECT) iodine quantification to distinguish hepatic neuroendocrine tumor (NET) metastasis from hepatocellular carcinoma (HCC) in non-cirrhotic liver parenchyma. MATERIAL AND METHODS:Forty-six patients (mean age, 64.9 ± 10....
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2018.05.019
更新日期:2018-08-01 00:00:00
abstract::Perfusion CT was first described in the 1970s but has become accepted as a clinical technique in recent years. In oncological practice Perfusion CT allows the downstream effects of therapies on the tumour vasculature to be monitored. From the dynamic changes in tumour and vascular enhancement following intravenous iod...
journal_title:European journal of radiology
pub_type: 杂志文章,评审
doi:10.1016/j.ejrad.2015.03.022
更新日期:2015-12-01 00:00:00
abstract:OBJECTIVE:To evaluate the efficacy and safety of sonography-guided percutaneous microwave ablation of intrahepatic primary cholangiocarcinoma. MATERIALS AND METHODS:From May 2006 to March 2010, 15 patients (11 men, 4 women; mean age, 57.4 years) with 24 histologically proven intrahepatic primary cholangiocarcinoma les...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2011.01.014
更新日期:2011-11-01 00:00:00
abstract:PURPOSE:We aimed to identify and assess cardiac abnormalities by cardiovascular magnetic resonance (CMR) in a non-ischaemic aborted sudden cardiac death (SCD) population and to establish possible predictors of SCD. METHODS:Thirty-six consecutive SCD survivors [median age 37.6 years (IQR 24.1-43.2), 31% female] with no...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2018.06.004
更新日期:2018-08-01 00:00:00
abstract::The ability of PI measurements to differentiate between acute rejection and ATN was investigated in 37 patients, who were frequently examined by duplex Doppler after kidney transplant. Absolute PI values as well as increase in PI were recorded and the clinical course was correlated with these pulsatility measurements....
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/0720-048x(92)90057-g
更新日期:1992-01-01 00:00:00
abstract:PURPOSE:To assess and quantify the prevalence and co-occurence of a sellar floor lowering and empty sella phenomenon in patients with GH (growth hormone)-secreting pituitary adenoma. METHODS:A total number of 159 acromegalic patients were included in this study, as well as two control groups (150 patients with non-GH-...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2018.05.009
更新日期:2018-07-01 00:00:00
abstract:PURPOSE:To compare the clinical utility of single-shot echo-planar imaging (SS-EPI) using different breathing schemes and readout-segmented EPI (RS-EPI) in the repeatability of apparent diffusion coefficient (ADC) measurements, signal-to-noise ratio (SNR) and image quality. METHODS:In this institutional review board-a...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2020.109472
更新日期:2021-02-01 00:00:00
abstract::The aim of this paper is to determine to what extent and in which cases 2D gradient echo (2D GE) sequences can be applied alternatively or additionally to spin echo (SE) sequences for improved diagnostic evaluation. Imaging with SE sequences is the most frequently used MR technique in the assessment of ear, nose and t...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/0720-048x(94)90364-6
更新日期:1994-02-01 00:00:00
abstract:PURPOSE:This survey was conducted to evaluate the radiation dose delivered to the patients through different CT procedures along with its corresponding risks in Yazd province. METHOD:Data for the five most common procedures were collected from six institutions from September 2017. The effective dose for each patient w...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2020.108932
更新日期:2020-05-01 00:00:00
abstract:PURPOSE:Magnetic resonance imaging (MRI) is one of the most widely used noninvasive diagnostic modalities for musculoskeletal evaluation. We conducted a retrospective study to determine whether MRI of the hip joint abductor and external rotator muscles yields reproducible findings in patients after total hip arthroplas...
journal_title:European journal of radiology
pub_type: 临床试验,杂志文章
doi:10.1016/j.ejrad.2011.01.113
更新日期:2012-05-01 00:00:00
abstract::Screening (early detection of disease in asymptomatic groups of persons) with whole-body MR (wb-MR) has only recently become possible. Technical requirements include extended scanner table range and extended coverage with surface coils. This allows for examining the whole body without repositioning the patient. wb-MR ...
journal_title:European journal of radiology
pub_type: 杂志文章,评审
doi:10.1016/j.ejrad.2009.02.011
更新日期:2009-06-01 00:00:00
abstract:PURPOSE:The purpose of this study was to evaluate if non-invasive Arterial Spin Labeling MR imaging can be used to assess changes in brain perfusion with age which reflect neonatal brain development. For this purpose regional perfusion values obtained with ASL MR imaging were evaluated as a function of postmenstrual ag...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2012.10.013
更新日期:2013-03-01 00:00:00
abstract::Congenital eventration of the diaphragm, as a cause of mediastinal mass, is an unusual condition and it may be unilateral or bilateral. Although this entity is frequently asymptomatic and firstly detected on the chest radiography, it may be difficult to distinguish a partial eventration from the other diaphragmatic le...
journal_title:European journal of radiology
pub_type: 杂志文章,评审
doi:10.1016/S0720-048X(03)00143-8
更新日期:2004-07-01 00:00:00
abstract:PURPOSE:To compare and outline the beneficial skills of combined (68)Ga-DOTATATE positron emission tomography (PET) with concurrent contrast enhanced X-ray computed tomography (ceCT) against stand-alone ceCT in 54 patients with neuroendocrine tumours (NET). METHODS:Patients with histologically confirmed NET and availa...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2015.06.024
更新日期:2015-10-01 00:00:00
abstract:PURPOSE:Quantification of tumour burden in oncology requires accurate and reproducible image evaluation. The current standard is one-dimensional measurement (e.g. RECIST) with inherent disadvantages. Volumetric analysis is discussed as an alternative for therapy monitoring of lung and liver metastases. The aim of this ...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2010.10.019
更新日期:2011-12-01 00:00:00
abstract::Pediatric projection imaging differs from imaging of the adult patient. Children are smaller, more radiosensitive, and less compliant than their adult counterparts. Their characteristics affect the way projection imaging is practiced and how dose is optimized. Computed radiography (CR) and digital radiography (DR) hav...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2009.03.003
更新日期:2009-11-01 00:00:00
abstract::To investigate whether there are significant changes in regional brain metabolism in patients with Parkinson's disease before and after thalamotomy using proton magnetic resonance spectroscopy (1H MRS). Fifteen patients underwent 15 stereotactic thalamotomies for control of medically refractory parkinsonian tremor. Si...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/s0720-048x(02)00211-5
更新日期:2003-09-01 00:00:00
abstract:OBJECTIVE:To obtain T2* and proton density measurements of normal human lung parenchyma in vivo using submillisecond echo time (TE) gradient echo (GRE) magnetic resonance (MR) imaging. MATERIALS AND METHODS:Six normal volunteers were scanned using a 1.5-T system equipped with a prototype enhanced gradient (GE Signa, W...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/s0720-048x(98)00169-7
更新日期:1999-03-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:The management of community-acquired pneumonia (CAP) depends, in part, on the identification of the causative agents. The objective of this study was to determine the potential of thin-section computed tomography (CT) in differentiating bacterial and non-bacterial pneumonia. PATIENTS AND METHO...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2008.08.004
更新日期:2009-12-01 00:00:00
abstract::The aim of the current study was to compare the diagnostic information obtained from a helical CT examination in low severity cervical spine trauma with that from a lateral CT scout view. We included alert and clinically stable patients, who had suffered acute blunt trauma of low or moderate severity. Their scout imag...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2009.03.024
更新日期:2010-07-01 00:00:00
abstract:PURPOSE:To evaluate the value of CT-based radiomics signature for differentiating Borrmann type IV gastric cancer (GC) from primary gastric lymphoma (PGL). MATERIALS AND METHODS:40 patients with Borrmann type IV GC and 30 patients with PGL were retrospectively recruited. 485 radiomics features were extracted and selec...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2017.04.007
更新日期:2017-06-01 00:00:00
abstract:PURPOSE:The aim of this study was to evaluate reproducibility of a fast MRI protocol to measure gastric emptying and motility of the gastric antrum. METHODS AND MATERIALS:Gastric emptying and antral speed were measured in 12 type 1 diabetic patients (mean age 43 years) and 9 healthy volunteers (mean age 31 years). Sub...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2009.04.071
更新日期:2010-08-01 00:00:00
abstract:INTRODUCTION:The purpose of this study is to determine the etiologies, histopathology and MDCT findings of children with fulminant hepatic failure admitted to our institution. MATERIALS AND METHODS:Between June 2004 and November 2006, 15 children with fulminant hepatic failure who underwent MDCT were included retrospe...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2008.07.020
更新日期:2009-11-01 00:00:00
abstract:PURPOSE:The study was performed to substantiate the value of detecting clips in mastectomy specimens as a guide to taking pathological samples. MATERIAL AND METHODS:We performed a retrospective review of 4 cases of mastectomy required after biopsies of microcalcifications. In each case a metallic clip had been inserte...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2007.10.014
更新日期:2009-02-01 00:00:00
abstract::A case is reported in which the typical radiographic appearances of acute emphysematous cholecystitis were due to acute gall bladder infarction following thrombotic occlusion of the superior mesenteric artery. ...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:
更新日期:1985-05-01 00:00:00
abstract:OBJECTIVE:Hypothyroidism is a common complication in patients receiving tyrosine kinase inhibitors. We evaluated the relationship between thyroid size evident on CT and thyroid function in patients with advanced renal cell carcinoma (RCC) receiving tyrosine kinase inhibitors. MATERIALS AND METHODS:Forty-two patients w...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2011.06.035
更新日期:2012-09-01 00:00:00
abstract::Bone marrow oedema is associated with a wide variety of pathological processes including both benign and malignant bone tumours. This imaging finding in relation to intraosseous tumours can aid in providing a more focused differential diagnosis. In this review, we will discuss the MR imaging of bone marrow oedema surr...
journal_title:European journal of radiology
pub_type: 杂志文章,评审
doi:10.1016/j.ejrad.2008.01.052
更新日期:2008-07-01 00:00:00
abstract::Light food diet and low residual diet with hydration, both combined with Proctosal and Bisacodyl cleansing, were compared in 268 patients in the preparation of the colon for double contrast examination. Low residual diet with hydration resulted in significantly less residual fecal material, no flocculation of the bari...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:
更新日期:1983-08-01 00:00:00