Abstract:
:Komagataeibacter nataicola is an acetic acid bacterium (AAB) that can produce abundant bacterial cellulose and tolerate high concentrations of acetic acid. To globally understand its fermentation characteristics, we present a high-quality complete genome sequence of K. nataicola RZS01. The genome consists of a 3,485,191-bp chromosome and 6 plasmids, which encode 3,514 proteins and bear three cellulose synthase operons. Phylogenetic analysis at the genome level provides convincing evidence of the evolutionary position of K. nataicola with respect to related taxa. Genomic comparisons with other AAB revealed that RZS01 shares 36.1%~75.1% of sequence similarity with other AAB. The sequence data was also used for metabolic analysis of biotechnological substrates. Analysis of the resistance to acetic acid at the genomic level indicated a synergistic mechanism responsible for acetic acid tolerance. The genomic data provide a viable platform that can be used to understand and manipulate the phenotype of K. nataicola RZS01 to further improve bacterial cellulose production.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Zhang H,Xu X,Chen X,Yuan F,Sun B,Xu Y,Yang J,Sun Ddoi
10.1038/s41598-017-04589-6subject
Has Abstractpub_date
2017-06-30 00:00:00pages
4431issue
1issn
2045-2322pii
10.1038/s41598-017-04589-6journal_volume
7pub_type
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