NMR-based metabolomics Reveals Alterations of Electro-acupuncture Stimulations on Chronic Atrophic Gastritis Rats.

abstract：:Different types of protein-protein interactions make different protein-protein interface patterns. Different machine learning methods are suitable to deal with different types of data. Then, is it the same situation that different interface patterns are preferred for prediction by different machine learning methods? H...

journal_title：Scientific reports

authors： Wang W,Yang Y,Yin J,Gong X

更新日期：2017-11-22 00:00:00

abstract：:Multidrug-resistant pathogens causing nosocomial and community acquired infections delineate a significant threat to public health. It had urged to identify new antimicrobials and thus, generated interest in studying macrocyclic metal complex, which has been studied in the past for their antimicrobial activity. Hence,...

journal_title：Scientific reports

authors： Brahma U,Kothari R,Sharma P,Bhandari V

更新日期：2018-05-23 00:00:00

abstract：:The helicase Twinkle is indispensable for mtDNA replication in nucleoids. Previously, we showed that Twinkle is tightly membrane-associated even in the absence of mtDNA, which suggests that Twinkle is part of a membrane-attached replication platform. Here we show that this platform is a cholesterol-rich membrane struc...

journal_title：Scientific reports

authors： Gerhold JM,Cansiz-Arda Ş,Lõhmus M,Engberg O,Reyes A,van Rennes H,Sanz A,Holt IJ,Cooper HM,Spelbrink JN

更新日期：2015-10-19 00:00:00

abstract：:Gestational diabetes mellitus (GDM) is a common health problem during pregnancy and its prevalence is increasing globally, especially in China. The aim of this study was to investigate socioeconomic, environmental and lifestyle factors associated with GDM in Chinese women. A matched pair case-control study was conduct...

journal_title：Scientific reports

authors： Carroll X,Liang X,Zhang W,Zhang W,Liu G,Turner N,Leeper-Woodford S

更新日期：2018-05-25 00:00:00

abstract：:Blowflies and houseflies are mechanical vectors inhabiting synanthropic environments around the world. They feed and breed in fecal and decaying organic matter, but the microbiome they harbour and transport is largely uncharacterized. We sampled 116 individual houseflies and blowflies from varying habitats on three co...

journal_title：Scientific reports

authors： Junqueira ACM,Ratan A,Acerbi E,Drautz-Moses DI,Premkrishnan BNV,Costea PI,Linz B,Purbojati RW,Paulo DF,Gaultier NE,Subramanian P,Hasan NA,Colwell RR,Bork P,Azeredo-Espin AML,Bryant DA,Schuster SC

更新日期：2017-11-24 00:00:00

abstract：:Gold is a noble metal typically stable as a solid in a face-centered cubic (FCC) structure under ambient conditions; however, under particular circumstances aberrant allotropes have been synthesized. In this work, we document the phase transformation of 25 nm thick nanocrystalline (NC) free-standing gold thin-film via...

journal_title：Scientific reports

authors： Suri PK,Nathaniel JE 2nd,Li N,Baldwin JK,Wang Y,Hattar K,Taheri ML

更新日期：2020-10-20 00:00:00

abstract：:To elucidate the temporal changes in the radiocesium distribution in forests contaminated by the Fukushima Daiichi Nuclear Power Plant accident, we monitored the 137Cs concentration and inventory within forests from 2011 to 2015 across nine plots containing variable tree species and different contamination levels. The...

journal_title：Scientific reports

authors： Imamura N,Komatsu M,Ohashi S,Hashimoto S,Kajimoto T,Kaneko S,Takano T

更新日期：2017-08-15 00:00:00

abstract：:The enzyme alanine racemase (Alr) has been a new target for the development of antibacterial drugs based on the involvement of D-Ala in bacterial cell wall biosynthesis. Our previous study noted that Alr is essential for the growth and interspecies competitiveness of S. mutans, the major causative organism of dental c...

journal_title：Scientific reports

authors： Liu S,Wei Y,Zhou X,Zhang K,Peng X,Ren B,Chen V,Cheng L,Li M

更新日期：2018-04-13 00:00:00

abstract：:Among the multiple metabolic signals involved in the establishment of the hepatic zonation, oxygen could play a key role. Indeed, depending on hepatocyte position in the hepatic lobule, gene expression and metabolism are differently affected by the oxygen gradient present across the lobule. The aim of this study is to...

journal_title：Scientific reports

authors： Tonon F,Giobbe GG,Zambon A,Luni C,Gagliano O,Floreani A,Grassi G,Elvassore N

更新日期：2019-09-19 00:00:00

abstract：:Excessive activation of inflammation and the accompanying lung vascular endothelial barrier disruption are primary pathogenic features of acute lung injury (ALI). Microtubule-associated protein 4 (MAP4), a tubulin assembly-promoting protein, is important for maintaining the microtubule (MT) cytoskeleton and cell-cell ...

journal_title：Scientific reports

authors： Li L,Hu J,He T,Zhang Q,Yang X,Lan X,Zhang D,Mei H,Chen B,Huang Y

更新日期：2015-03-09 00:00:00

abstract：:Human adenoviruses (HAdVs) shut down host cellular cap-dependent mRNA translation while initiating the translation of viral late mRNAs in a cap-independent manner. HAdV 5' untranslated regions (5'UTRs) are crucial for cap-independent initiation, and influence mRNA localization and stability. However, HAdV translationa...

journal_title：Scientific reports

authors： Ramke M,Lee JY,Dyer DW,Seto D,Rajaiya J,Chodosh J

更新日期：2017-04-04 00:00:00

abstract：:Flooding is one of the major constraints for rice production in rainfed lowlands, especially in years and areas of high rainfall. Incorporating the Sub1 (Submergence1) gene into high yielding popular varieties has proven to be the most feasible approach to sustain rice production in submergence-prone areas. Introgress...

journal_title：Scientific reports

authors： Dar MH,Zaidi NW,Waza SA,Verulkar SB,Ahmed T,Singh PK,Roy SKB,Chaudhary B,Yadav R,Islam MM,Iftekharuddaula KM,Roy JK,Kathiresan RM,Singh BN,Singh US,Ismail AM

更新日期：2018-06-18 00:00:00

abstract：:Current anti-influenza therapy depends on administering drugs soon after infection, which is often impractical. We assessed whether combinations of oseltamivir (a neuraminidase inhibitor) and T-705 (a nonspecific inhibitor of viral polymerases) could extend the window for treating lethal infection with highly pathogen...

journal_title：Scientific reports

authors： Marathe BM,Wong SS,Vogel P,Garcia-Alcalde F,Webster RG,Webby RJ,Najera I,Govorkova EA

更新日期：2016-05-25 00:00:00

abstract：:Willow (Salix spp.) seeds are able to tolerate desiccation, but differ from typical orthodox seeds in that they lose viability in a few days at room temperature, and in that the chloroplasts in embryo tissues do not dedifferentiate during maturation drying, thus retaining chlorophyll and maintaining intact their thyla...

journal_title：Scientific reports

authors： López-Fernández MP,Moyano L,Correa MD,Vasile F,Burrieza HP,Maldonado S

更新日期：2018-11-21 00:00:00

abstract：:V-domain immunoglobulin (Ig) suppressor of T cell activation (VISTA) is an immune checkpoint that maintains peripheral T cell quiescence and inhibits anti-tumor immune responses. VISTA functions by dampening the interaction between myeloid cells and T cells, orthogonal to PD-1 and other checkpoints of the tumor-T cell...

journal_title：Scientific reports

authors： Mehta N,Maddineni S,Kelly RL,Lee RB,Hunter SA,Silberstein JL,Parra Sperberg RA,Miller CL,Rabe A,Labanieh L,Cochran JR

更新日期：2020-09-16 00:00:00

abstract：:FMS-like tyrosine kinase 3 (FLT3) is a key driver of acute myeloid leukemia (AML). Several tyrosine kinase inhibitors (TKIs) targeting FLT3 have been evaluated clinically, but their effects are limited when used in monotherapy due to the emergence of drug-resistance. Thus, a better understanding of drug-resistance pat...

journal_title：Scientific reports

authors： Morales ML,Arenas A,Ortiz-Ruiz A,Leivas A,Rapado I,Rodríguez-García A,Castro N,Zagorac I,Quintela-Fandino M,Gómez-López G,Gallardo M,Ayala R,Linares M,Martínez-López J

更新日期：2019-12-09 00:00:00

abstract：:The pentameric serum IgMs are critical to immune defense and surveillance through cytotoxicity against microbes and nascent cancer cells. Ficolins, a group of oligomeric lectins with an overall structure similar to C1q and mannose-binding lectin (MBL) participate in microbe infection and apoptotic cell clearance by ac...

journal_title：Scientific reports

authors： Lei X,Liu C,Azadzoi K,Li C,Lu F,Xiang A,Sun J,Guo Y,Zhao Q,Yan Z,Yang J

更新日期：2015-01-16 00:00:00

abstract：:The study of mechanisms that govern feeding behaviour and its related disorders is a matter of global health interest. The roundworm Caenorhabditis elegans is becoming a model organism of choice to study these conserved pathways. C. elegans feeding depends on the contraction of the pharynx (pumping). Thanks to the wor...

journal_title：Scientific reports

authors： Rodríguez-Palero MJ,López-Díaz A,Marsac R,Gomes JE,Olmedo M,Artal-Sanz M

更新日期：2018-02-26 00:00:00

abstract：:Human respiratory syncytial virus (RSV) A ON1 genotype, first detected in 2010 in Ontario, Canada, has been documented in 21 countries to date. This study investigated persistence and transmission dynamics of ON1 by grouping 406 randomly selected RSV-positive specimens submitted to Public Health Ontario from August 20...

journal_title：Scientific reports

authors： Duvvuri VR,Granados A,Rosenfeld P,Bahl J,Eshaghi A,Gubbay JB

更新日期：2015-09-30 00:00:00

abstract：:We have studied an expansion behavior of pressurized bubbles at the orifice of a capillary inserted in gelator-solvent (agarose-water) mixtures as a function of the gelator concentration in which the phase transition points are included. The pressure (P) -dependence of the radius of the curvature (R) of the bubbles mo...

journal_title：Scientific reports

authors： Ichinose N,Ura H

更新日期：2020-02-14 00:00:00

abstract：:A new, composite plasmonic waveguide based electromagnetic cloaking scheme is proposed with Si nano-spacer. Here we show, that the scattering fields of an object located on the cloak do not interact with the evanescent field, resulting in object's invisibility. Finite difference time domain (FDTD) numerical calculatio...

journal_title：Scientific reports

authors： Galutin Y,Falek E,Karabchevsky A

更新日期：2017-09-21 00:00:00

abstract：:Although the reversible wettability transition between hydrophobic and hydrophilic graphene under ultraviolet (UV) irradiation has been observed, the mechanism for this phenomenon remains unclear. In this work, experimental and theoretical investigations demonstrate that the H2O molecules are split into hydrogen and h...

journal_title：Scientific reports

authors： Xu Z,Ao Z,Chu D,Younis A,Li CM,Li S

更新日期：2014-09-23 00:00:00

abstract：:Due to the substantial limitation of study population, Spindle cell sarcoma (SCS) was unexplored comprehensively. In this study, we investigated the clinical characteristics and disease specific prognostic factors of SCS. 3299 SCS cases were identified and extracted from Surveillance, Epidemiology, and End Results (SE...

journal_title：Scientific reports

authors： Feng L,Wang M,Yibulayin F,Zhang H,Yang YL,Ren F,Wushou A

更新日期：2018-03-22 00:00:00

abstract：:Expression of various molecules on the surface of cancer cells compared to normal cells creates a platform for the generation of various drug vehicles for targeted therapy. Multiple interactions between ligands and their receptors mediated by targeting peptide-modified polymer could enable simultaneous delivery of a d...

journal_title：Scientific reports

authors： Sarangthem V,Cho EA,Yi A,Kim SK,Lee BH,Park RW

更新日期：2018-03-01 00:00:00

abstract：:Artificial grasslands play a role in carbon storage on the Qinghai-Tibetan Plateau. The artificial grasslands exhibit decreased proportions of graminate and increased species richness with age. However, the effect of the graminate proportions and species richness on ecosystem C stocks in artificial grasslands have not...

journal_title：Scientific reports

authors： Xu L,Yao B,Wang W,Wang F,Zhou H,Shi J,Zhao X

更新日期：2017-01-09 00:00:00

abstract：:Fibrates, which are widely used lipidaemic-modulating drugs, are emerging environmental pollutants. However, fibrate concentrations in the environment have not been thoroughly surveyed. Here, we determined concentrations of the most commonly used fibrates and their metabolites in source water and drinking water sample...

journal_title：Scientific reports

authors： Ido A,Hiromori Y,Meng L,Usuda H,Nagase H,Yang M,Hu J,Nakanishi T

更新日期：2017-04-12 00:00:00

abstract：:Solid state memory and switching devices aimed at replacing the flash memory technology operate by switching from the high to low resistance when conductive filaments are created in response to the electric pulse. The filaments are identified with either structurally different protrusions or purely electronic conducti...

journal_title：Scientific reports

authors： Karpov VG,Niraula D

更新日期：2018-08-15 00:00:00

abstract：:Efficient interventions to reduce blood triglycerides are few; newer and more tolerable intervention targets are needed. Understanding the molecular mechanisms underlying blood triglyceride levels variation is key to identifying new therapies. To explore the role of epigenetic mechanisms on triglyceride levels, a bloo...

journal_title：Scientific reports

authors： Truong V,Huang S,Dennis J,Lemire M,Zwingerman N,Aïssi D,Kassam I,Perret C,Wells P,Morange PE,Wilson M,Trégouët DA,Gagnon F

更新日期：2017-09-11 00:00:00

abstract：:Zeolites/molecular sieves with uniform, molecular-sized pores are important for many adsorption-based separation processes. Pore size gaps, however, exist in the current zeolite family. This leads to a great challenge of separating molecules with size differences at ~0.01 nm level. Here, we report a novel concept, por...

journal_title：Scientific reports

authors： Song Z,Huang Y,Xu WL,Wang L,Bao Y,Li S,Yu M

更新日期：2015-09-11 00:00:00

abstract：:An impairment of cardiac function is a key feature of the cardiovascular failure associated with sepsis. Although there is some evidence that suppression of sarcoplasmic reticulum Ca2+-ATP-ase (SERCA2) contributes to septic cardiomyopathy, it is not known whether prevention of the down-regulation of SERCA2 improves ou...

journal_title：Scientific reports

authors： Martin L,Horst K,Chiazza F,Oggero S,Collino M,Brandenburg K,Hildebrand F,Marx G,Thiemermann C,Schuerholz T

更新日期：2016-11-17 00:00:00