Identification of Methylation-Driven, Differentially Expressed STXBP6 as a Novel Biomarker in Lung Adenocarcinoma.

abstract：:With the surge of GPS-technology, many studies uncovered space use of mobile animals and shed light on the underlying behavioral mechanisms of habitat selection. Habitat selection and variation in either occurrence or strength of functional responses (i.e. how selection changes with availability) have given new insigh...

journal_title：Scientific reports

authors： William G,Jean-Michel G,Sonia S,Christophe B,Atle M,Nicolas M,Maryline P,Clément C

更新日期：2018-03-23 00:00:00

abstract：:Atomistic molecular dynamics simulations were performed with 13 non-peptidic neurotransmitters (NTs) in three different membrane environments. The results provide compelling evidence that NTs are divided into membrane-binding and membrane-nonbinding molecules. NTs adhere to the postsynaptic membrane surface whenever t...

journal_title：Scientific reports

authors： Postila PA,Vattulainen I,Róg T

更新日期：2016-01-19 00:00:00

abstract：:One of the greatest enigmas of modern biology is how the geometry of muscular and skeletal structures are created and how their development is controlled during growth and regeneration. Scaling and shaping of vertebrate muscles and skeletal elements has always been enigmatic and required an advanced technical level in...

journal_title：Scientific reports

authors： Tesařová M,Mancini L,Simon A,Adameyko I,Kaucká M,Elewa A,Lanzafame G,Zhang Y,Kalasová D,Szarowská B,Zikmund T,Novotná M,Kaiser J

更新日期：2018-09-20 00:00:00

abstract：:The Vavilov Institute of Plant Genetic Resources (VIR), in St. Petersburg, Russia, houses a unique genebank, with historical collections of landraces. When they were collected, the geographical distribution and genetic diversity of most crops closely reflected their historical patterns of cultivation established over ...

journal_title：Scientific reports

authors： Plekhanova E,Vishnyakova MA,Bulyntsev S,Chang PL,Carrasquilla-Garcia N,Negash K,Wettberg EV,Noujdina N,Cook DR,Samsonova MG,Nuzhdin SV

更新日期：2017-07-06 00:00:00

abstract：:The relationship between biodiversity and ecological functioning is a central issue in freshwater ecology, but how this relationship is influenced by hydrological connectivity stress is still unknown. In this study we analyzed the dynamic of the phytoplankton alpha diversity indices and their relationships with trophi...

journal_title：Scientific reports

authors： Meng F,Li Z,Li L,Lu F,Liu Y,Lu X,Fan Y

更新日期：2020-12-07 00:00:00

abstract：:As an analytic pipeline for quantitative imaging feature extraction and analysis, radiomics has grown rapidly in the past decade. On the other hand, recent advances in deep learning and transfer learning have shown significant potential in the quantitative medical imaging field, raising the research question of whethe...

journal_title：Scientific reports

authors： Zhang Y,Lobo-Mueller EM,Karanicolas P,Gallinger S,Haider MA,Khalvati F

更新日期：2021-01-14 00:00:00

abstract：:Non-alcoholic fatty liver disease (NAFLD) is a chronic disease with several degrees of histological features which may progress to cirrhosis. Obesity is an important risk factor and although NAFLD has no specific pharmacological treatment, bariatric surgery has been associated with NAFLD regression in severely obese p...

journal_title：Scientific reports

authors： Chaim FDM,Pascoal LB,Chaim FHM,Palma BB,Damázio TA,da Costa LBE,Carvalho R,Cazzo E,Gestic MA,Utrini MP,Milanski M,Chaim EA,Leal RF

更新日期：2020-05-22 00:00:00

abstract：:Whether an infectious disease threat to wildlife arises from pathogen introduction or the increased incidence of an already-present agent informs mitigation policy and actions. The prior absence of a pathogen can be difficult to establish, particularly in free-living wildlife. Subsequent to the epidemic emergence of t...

journal_title：Scientific reports

authors： Cunningham AA,Smith F,McKinley TJ,Perkins MW,Fitzpatrick LD,Wright ON,Lawson B

更新日期：2019-03-12 00:00:00

abstract：:Two of the most common nonhuman animals that interact with humans are domestic dogs (Canis familiaris) and cats (Felis catus). In contrast to dogs, the ability of domestic cats to communicate with humans has not been explored thoroughly. We used a habituation-dishabituation method to investigate whether domestic cats ...

journal_title：Scientific reports

authors： Saito A,Shinozuka K,Ito Y,Hasegawa T

更新日期：2019-04-04 00:00:00

abstract：:Rapid eye movement (REM) sleep is considered to preferentially reprocess emotionally arousing memories. We tested this hypothesis by cueing emotional vs. neutral memories during REM and NREM sleep and wakefulness by presenting associated verbal memory cues after learning. Here we show that cueing during NREM sleep sig...

journal_title：Scientific reports

authors： Lehmann M,Schreiner T,Seifritz E,Rasch B

更新日期：2016-12-16 00:00:00

abstract：:Scattered and indirect evidence suggests that sea ice occurred as far south as the Iceland Sea during the Early Pliocene, when the global climate was warmer than present. However, conclusive evidence as well as potential mechanisms governing sea ice occurrence outside the Arctic Ocean during a time with elevated green...

journal_title：Scientific reports

authors： Clotten C,Stein R,Fahl K,Schreck M,Risebrobakken B,De Schepper S

更新日期：2019-01-30 00:00:00

abstract：:Rivers are an important aquatic conduit that connects terrestrial sources of dissolved inorganic carbon (DIC) and other elements with oceanic reservoirs. The Mekong River, one of the world's largest rivers, is firstly examined to explore inter-annual fluxes of dissolved and particulate constituents during 1923-2011 an...

journal_title：Scientific reports

authors： Li S,Bush RT

更新日期：2015-11-02 00:00:00

abstract：:Condensin complexes play crucial roles in chromosome condensation that is a fundamental process to establish the "rod-like" shape of chromosome structure in mitosis. Failure of the chromosome assembly causes chromosome segregation errors and subsequent genomic instability. However, a molecular mechanism that controls ...

journal_title：Scientific reports

authors： Kagami Y,Ono M,Yoshida K

更新日期：2017-07-17 00:00:00

abstract：:Glucocorticoid receptor (GR) is a hormone-activated transcription regulatory protein involved in metabolism as well as adrenocortical responses to psychosocial stress. Ligand-activated GR localizes to the nucleus, where GR homodimers regulate gene transcription via direct binding to glucocorticoid response elements (G...

journal_title：Scientific reports

authors： Oasa S,Mikuni S,Yamamoto J,Kurosaki T,Yamashita D,Kinjo M

更新日期：2018-05-10 00:00:00

abstract：:Control of genetic regulatory networks is challenging to define and quantify. Previous control centrality metrics, which aim to capture the ability of individual nodes to control the system, have been found to suffer from plausibility and applicability problems. Here we present a new approach to control centrality bas...

journal_title：Scientific reports

authors： Karl S,Dandekar T

更新日期：2015-06-11 00:00:00

abstract：:Gentamicin may cause acute kidney injury. The pathogenesis of gentamicin nephrotoxicity is unclear. Autophagy is a highly conserved physiological process involved in removing damaged or aged biological macromolecules and organelles from the cytoplasm. The role of autophagy in the pathogenesis of gentamicin nephrotoxic...

journal_title：Scientific reports

authors： Cui J,Bai XY,Sun X,Cai G,Hong Q,Ding R,Chen X

更新日期：2015-06-08 00:00:00

abstract：:HilD is an AraC-like transcriptional regulator encoded in the Salmonella pathogenicity island 1 (SPI-1), which actives transcription of many genes within and outside SPI-1 that are mainly required for invasion of Salmonella into host cells. HilD controls expression of target genes directly or by acting through distinc...

journal_title：Scientific reports

authors： Banda MM,Manzo R,Bustamante VH

更新日期：2019-09-04 00:00:00

abstract：:III-nitride materials have been linked with a vast number of exciting applications from power electronics to solar cells. Herein, polycrystalline InN, GaN and systematically controlled InxGa1-xN composite thin films are fabricated on FTO glass by a facile, low-cost and scalable aerosol assisted chemical vapor depositi...

journal_title：Scientific reports

authors： McInnes A,Sagu JS,Mehta D,Wijayantha KGU

更新日期：2019-02-19 00:00:00

abstract：:Understanding the factors that enable mutualisms to evolve and to subsequently remain stable over time, is essential to fully understand patterns of global biodiversity and for evidence based conservation policy. Theoretically, spatial heterogeneity of mutualists, through increased likelihood of fidelity between coope...

journal_title：Scientific reports

authors： Wang RW,Dunn DW,Luo J,He JZ,Shi L

更新日期：2015-10-05 00:00:00

abstract：:A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper. ...

journal_title：Scientific reports

authors： Radeck J,Meyer D,Lautenschläger N,Mascher T

更新日期：2018-03-06 00:00:00

abstract：:Electrochemical pre-doping of a silicon electrode was investigated to create a new class of rechargeable battery with higher energy density. The electrochemical reaction during pre-doping formed a high-quality solid electrolyte interface (SEI) on the surface of silicon particles, which improved the charge and discharg...

journal_title：Scientific reports

authors： Wang Y,Satoh M,Arao M,Matsumoto M,Imai H,Nishihara H

更新日期：2020-02-21 00:00:00

abstract：:A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has not been fixed in the paper. ...

journal_title：Scientific reports

authors： Reslova N,Huvarova V,Hrdy J,Kasny M,Kralik P

更新日期：2019-04-04 00:00:00

abstract：:Complex associations exist between inflammation and thrombosis, with the inflammatory state tending to promote coagulation. Fibrinogen, an acute phase protein, has been shown to interact with the amyloidogenic ß-amyloid protein of Alzheimer's disease. However, little is known about the association between fibrinogen a...

journal_title：Scientific reports

authors： Page MJ,Thomson GJA,Nunes JM,Engelbrecht AM,Nell TA,de Villiers WJS,de Beer MC,Engelbrecht L,Kell DB,Pretorius E

更新日期：2019-02-28 00:00:00

abstract：:Oral lichen planus (OLP) is a common, chronic relapsing inflammatory disorder of the mucous membranes, which causes major discomfort. Current treatment includes topical/systemic glucocorticoids, immune modulators and systemic immunosuppressants, which may lead to considerable side-effects. The aim of this study was to...

journal_title：Scientific reports

authors： Cosgarea R,Pollmann R,Sharif J,Schmidt T,Stein R,Bodea A,Auschill T,Sculean A,Eming R,Greene B,Hertl M,Arweiler N

更新日期：2020-02-03 00:00:00

abstract：:Fuelled by a desire for greater connectivity, networked systems now pervade our society at an unprecedented level that will affect it in ways we do not yet understand. In contrast, nature has already developed efficient networks that can instigate rapid response and consensus when key elements are stimulated. We prese...

journal_title：Scientific reports

authors： Clark R,Punzo G,Macdonald M

更新日期：2019-11-26 00:00:00

abstract：:Dairy cows are often fed a high-concentrate (HC) diet to meet lactation demands; however, long-term concentrate feeding is unhealthy and decreases milk fat. Therefore, we investigated the effects of liver lipid metabolism on milk fat synthesis. Ten lactating Holstein cows were assigned randomly into HC and LC (low-con...

journal_title：Scientific reports

authors： Li L,Cao Y,Xie Z,Zhang Y

更新日期：2017-03-13 00:00:00

abstract：:Plumbagin, an anti-cancer agent, is toxic to cells of multiple species. We investigated if plumbagin targets conserved biochemical processes. Plumbagin induced DNA damage and apoptosis in cells of diverse mutational background with comparable potency. A 3-5 fold increase in intracellular oxygen radicals occurred in re...

journal_title：Scientific reports

authors： Kapur A,Beres T,Rathi K,Nayak AP,Czarnecki A,Felder M,Gillette A,Ericksen SS,Sampene E,Skala MC,Barroilhet L,Patankar MS

更新日期：2018-01-18 00:00:00

abstract：:Cerebral lateralization is expressed at both the structural and functional levels, and can exist as either a stable characteristic or as a dynamic feature during behavior and development. The anatomically relatively simple olfactory system demonstrates lateralization in both human and non-human animals. Here, we explo...

journal_title：Scientific reports

authors： Cohen Y,Wilson DA

更新日期：2017-11-06 00:00:00

abstract：:Plants adapted to extreme conditions can be at high risk from climate change; arctic-alpine plants, in particular, could "run out of space" as they are out-competed by expansion of woody vegetation. Mountain regions could potentially provide safe sites for arctic-alpine plants in a warmer climate, but empirical eviden...

journal_title：Scientific reports

authors： Clarke CL,Edwards ME,Gielly L,Ehrich D,Hughes PDM,Morozova LM,Haflidason H,Mangerud J,Svendsen JI,Alsos IG

更新日期：2019-12-23 00:00:00

abstract：:This work reports the oxygen reduction reaction (ORR) kinetics of metal nanoparticle catalysts between 500 and 600 °C at low oxygen partial pressures. Ex situ and in situ TEM measurements demonstrate catalyzed nanowire growth initially follows linear kinetics; characteristic of being ORR rate limited. The ORR rates of...

journal_title：Scientific reports

authors： Sun K,Xue J,Tai K,Dillon SJ

更新日期：2017-08-01 00:00:00