Abstract：
:Plants adapted to extreme conditions can be at high risk from climate change; arctic-alpine plants, in particular, could "run out of space" as they are out-competed by expansion of woody vegetation. Mountain regions could potentially provide safe sites for arctic-alpine plants in a warmer climate, but empirical evidence is fragmentary. Here we present a 24,000-year record of species persistence based on sedimentary ancient DNA (sedaDNA) from Lake Bolshoye Shchuchye (Polar Urals). We provide robust evidence of long-term persistence of arctic-alpine plants through large-magnitude climate changes but document a decline in their diversity during a past expansion of woody vegetation. Nevertheless, most of the plants that were present during the last glacial interval, including all of the arctic-alpines, are still found in the region today. This underlines the conservation significance of mountain landscapes via their provision of a range of habitats that confer resilience to climate change, particularly for arctic-alpine taxa.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Clarke CL,Edwards ME,Gielly L,Ehrich D,Hughes PDM,Morozova LM,Haflidason H,Mangerud J,Svendsen JI,Alsos IGdoi
10.1038/s41598-019-55989-9subject
Has Abstractpub_date
2019-12-23 00:00:00pages
19613issue
1issn
2045-2322pii
10.1038/s41598-019-55989-9journal_volume
9pub_type
杂志文章abstract：:Human respiratory syncytial virus (RSV) A ON1 genotype, first detected in 2010 in Ontario, Canada, has been documented in 21 countries to date. This study investigated persistence and transmission dynamics of ON1 by grouping 406 randomly selected RSV-positive specimens submitted to Public Health Ontario from August 20...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep14268
更新日期：2015-09-30 00:00:00
abstract：:Learning disability varies by month of conception. The underlying mechanism is unknown but vitamin D, necessary for normal brain development, is commonly deficient over winter in high latitude countries due to insufficient ultraviolet radiation. We linked the 2007-2016 Scottish School Pupil Censuses to Scottish matern...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-45562-9
更新日期：2019-06-27 00:00:00
abstract：:miR1444s are functionally significant miRNAs targeting polyphenol oxidase (PPO) genes for cleavage. MIR1444 genes were reported only in Populus trichocarpa. Through the computational analysis of 215 RNA-seq data, four whole genome sequences of Salicaceae species and deep sequencing of six P. trichocarpa small RNA libr...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep39740
更新日期：2017-01-10 00:00:00
abstract：:China has one of the highest rates of cesarean sections in the world. However, limited epidemiological studies have evaluated the risk factors for cesarean section among Chinese women. Thus, the aim of this cohort study was to investigate the associations between pre-pregnancy BMI, gestational weight gain (GWG) and th...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep37168
更新日期：2016-11-22 00:00:00
abstract：:BMPs are multifunctional growth factors implicated in regulating the ovarian function as key intra-ovarian factors. Biological effects of BMPs are mediated through binding with membrane bound receptors like BMPR-IB and initiating downstream Smad signaling pathway. FecB mutation, regarded as a loss of function mutation...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-77596-9
更新日期：2020-11-24 00:00:00
abstract：:There is growing interest in the conservation and utilization of crop wild relatives (CWR) in international food security policy and research. Legumes play an important role in human health, sustainable food production, global food security, and the resilience of current agricultural systems. Pea belongs to the ancien...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-17623-4
更新日期：2017-12-12 00:00:00
abstract：:Thermo-elasticity couples the deformation of an elastic (solid) body to its temperature and vice-versa. It is a solid-like property. Highlighting such property in liquids is a paradigm shift: it requires long-range collective interactions that are not considered in current liquid descriptions. The present microthermal...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-69404-1
更新日期：2020-08-07 00:00:00
abstract：:In this paper, we present the first realization of an elastic metamaterial allowing independent tuning of negative density and stiffness for elastic waves propagating along a designated direction. In electromagnetic (or acoustic) metamaterials, it is now possible to tune permittivity (bulk modulus) and permeability (d...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep23630
更新日期：2016-03-23 00:00:00
abstract：:Cardiac fibroblasts are present throughout the myocardium and are enriched in the microenvironment surrounding the ventricular conduction system (VCS). Several forms of arrhythmias are linked to VCS abnormalities, but it is still unclear whether VCS malformations are cardiomyocyte autonomous or could be linked to cros...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-73159-0
更新日期：2020-09-30 00:00:00
abstract：:The early life stages represent a crucial period that can strongly influence population dynamics. We studied the development of foraging behaviour in the red-footed booby, a tropical seabird with an extensive post-fledging care period (3 to 6 months). Adults and juveniles were observed from shore and tracked at sea us...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-14478-7
更新日期：2017-10-24 00:00:00
abstract：:The quantum mechanical motion of electrons and nuclei in systems spatially confined to the molecular dimensions occurs on the sub-femtosecond to the femtosecond timescales respectively. Consequently, the study of ultrafast electronic and, in specific cases, nuclear dynamics requires the availability of light pulses wi...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-60331-9
更新日期：2020-02-28 00:00:00
abstract：:Peritrichously-flagellated bacteria, such as Escherichia coli, self-propel in fluids by using specialised motors to rotate multiple helical filaments. The rotation of each motor is transmitted to a short flexible segment called the hook which in turn transmits it to a flagellar filament, enabling swimming of the whole...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-28319-8
更新日期：2018-07-16 00:00:00
abstract：:Neurofeedback-guided motor imagery training (NF-MIT) has been suggested as a promising therapy for stroke-induced motor impairment. Whereas much NF-MIT research has aimed at signal processing optimization, the type of sensory feedback given to the participant has received less attention. Often the feedback signal is h...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep37696
更新日期：2016-11-21 00:00:00
abstract：:Living organisms employ various mechanisms to escape harm. At the cellular level, mobile cells employ movement to avoid harmful chemicals or repellents. The present study is the first to report that cells move away from the site of injury in response to local wounding. When a migrating Dictyostelium cell was locally w...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-39678-1
更新日期：2019-03-12 00:00:00
abstract：:Limbal stem cell deficiency can be treated with transplantation of cultured human limbal epithelial cells (LEC). It can be advantageous to produce LEC in centralized labs and thereafter ship them to eye clinics. The present study used transport simulations of LEC to determine if vigorous shaking during transport alter...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-28553-0
更新日期：2018-07-12 00:00:00
abstract：:Nitrogen (N) is a major component of the photosynthetic apparatus and is widely used as a fertilizer in crops. However, to the best of our knowledge, the dynamic of photosynthesis establishment due to differential N supply in the bioenergy crop sugarcane has not been reported to date. To address this question, we eval...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-20653-1
更新日期：2018-02-02 00:00:00
abstract：:Adenoviruses are very efficient vectors for delivering therapeutic genes in preclinical and clinical trials. However, randomized controlled human trials have often been lacking clear clinically relevant results. We hypothesized that high lipid levels and specific lipoproteins could significantly decrease adenoviral tr...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-00376-5
更新日期：2017-03-24 00:00:00
abstract：:After hepatic microwave ablation, the differentiation between fully necrotic and persistent vital tissue through contrast enhanced CT remains a clinical challenge. Therefore, there is a need to evaluate new imaging modalities, such as CT perfusion (CTP) to improve the visualization of coagulation necrosis. MWA and CTP...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-55026-9
更新日期：2019-12-06 00:00:00
abstract：:Chronic obstructive pulmonary disease (COPD) patients are at higher risk of developing lung cancer and its metastasis, but no suitable biomarker has been reported for differential diagnosis of these patients. Levels of serum biomarkers (VEGF, IL-8, MMP-9 and MMP-2) were analyzed in these patients, which were compared ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep36065
更新日期：2016-11-04 00:00:00
abstract：:The development of 2D nanomaterial coatings across metal surfaces is a challenge due to the mismatch between the metal microstructure and the nanoscale materials. The naturally occurring thin oxidative layer present across all metal surfaces, may lead to low adherence and connectivity. In this paper, graphene/titania/...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-26447-9
更新日期：2018-05-25 00:00:00
abstract：:The hypothalamic-pituitary-adrenal (HPA) axis is an important component of neuroendocrine stress regulation and coping behavior. Transcriptome profiles of the hypothalamus and adrenal gland were assessed to identify molecular pathways and candidate genes for coping behavior in pigs. Ten each of high- (HR) and low- (LR...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-49521-2
更新日期：2019-09-10 00:00:00
abstract：:Fire-induced permafrost degradation is well documented in boreal forests, but the role of fires in initiating thermokarst development in Arctic tundra is less well understood. Here we show that Arctic tundra fires may induce widespread thaw subsidence of permafrost terrain in the first seven years following the distur...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep15865
更新日期：2015-10-29 00:00:00
abstract：:Understanding the molecular mechanism by which epithelial mesenchymal transition (EMT)-mediated cancer metastasis and how microRNA (miRNA) regulates lung cancer progression via Twist1-activated EMT may provide potential therapeutic targets for cancer therapy. Here we found that miR-33a, an intronic miRNA located withi...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep13677
更新日期：2015-09-02 00:00:00
abstract：:Strenuous exercise increases circulating cell free DNA (cfDNA) and stimulates blood phagocytes to generate reactive oxygen species (ROS) which may induce DNA strand breaks. We tested whether: (A) elevated cfDNA in response to three repeated bouts of exhaustive exercise has decreased integrity; (B) each bout of exercis...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-52409-w
更新日期：2019-11-04 00:00:00
abstract：:Efficient mitochondrial Ca2+ uptake takes place at contact points between the ER and mitochondria, and represents a key regulator of many cell functions. In a previous study with HeLa cells, we showed that ER-to-mitochondria Ca2+ transfer increases during the early phase of ER stress induced by tunicamycin as an adapt...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep36394
更新日期：2016-11-03 00:00:00
abstract：:Cisplatin is a highly effective anti-cancer chemotherapeutic agent; however, its clinical use is severely limited by serious side effects, of which nephrotoxicity is the most important. In this study, we investigated whether Qiong-Yu-Gao (QYG), a popular traditional Chinese medicinal formula described 840 years ago, e...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep15592
更新日期：2015-10-29 00:00:00
abstract：:Allelic differential expression (ADE) is common in diploid organisms, and is often the key reason for specific phenotype variations. Thus, ADE detection is important for identification of major genes and causal mutations. To date, sensitive and simple methods to detect ADE are still lacking. In this study, we have dev...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-42815-5
更新日期：2019-04-19 00:00:00
abstract：:We propose and demonstrate a type of a broadband half-wave plate that operates in the reflective mode. It consists of a metal grating embedded in a dielectric slab and placed on top of a grounded metal surface. We theoretically show that owing to the optical feedback effect which originates from the wave reflections a...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-09561-y
更新日期：2017-08-22 00:00:00
abstract：:A novel one-pot synthesis of tri-substituted purines and the discovery of purine analogues with trypanocidal activity are reported. The reaction is initiated by a metal-free oxidative coupling of primary alkoxides and diaminopyrimidines with Schiff base formation and subsequent annulation in the presence of large N,N-...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep09139
更新日期：2015-03-16 00:00:00
abstract：:Campylobacter hyointestinalis is a member of an emerging group of zoonotic Campylobacter spp. that are increasingly identified in both gastric and non-gastric disease in humans. Here, we discovered C. hyointestinalis in three separate classes of New Zealand ruminant livestock; cattle, sheep and deer. To investigate th...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-20889-x
更新日期：2018-02-05 00:00:00
