Abstract：
:Rivers are an important aquatic conduit that connects terrestrial sources of dissolved inorganic carbon (DIC) and other elements with oceanic reservoirs. The Mekong River, one of the world's largest rivers, is firstly examined to explore inter-annual fluxes of dissolved and particulate constituents during 1923-2011 and their associated natural or anthropogenic controls. Over this period, inter-annual fluxes of dissolved and particulate constituents decrease, while anthropogenic activities have doubled the relative abundance of SO4(2-), Cl(-) and Na(+). The estimated fluxes of solutes from the Mekong decrease as follows (Mt/y): TDS (40.4) > HCO3(-) (23.4) > Ca(2+) (6.4) > SO4(2-) (3.8) > Cl(-) (1.74)~Na(+) (1.7) ~ Si (1.67) > Mg(2+) (1.2) > K(+ 0.5). The runoff, land cover and lithological composition significantly contribute to dissolved and particulate yields globally. HCO3(-) and TDS yields are readily predicted by runoff and percent of carbonate, while TSS yield by runoff and population density. The Himalayan Rivers, including the Mekong, are a disproportionally high contributor to global riverine carbon and other solute budgets, and are of course underlined. The estimated global riverine HCO3(-) flux (Himalayan Rivers included) is 34,014 × 10(9) mol/y (0.41 Pg C/y), 3915 Mt/y for solute load, including HCO3(-), and 13,553 Mt/y for TSS. Thereby this study illustrates the importance of riverine solute delivery in global carbon cycling.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Li S,Bush RTdoi
10.1038/srep16005subject
Has Abstractpub_date
2015-11-02 00:00:00pages
16005issn
2045-2322pii
srep16005journal_volume
5pub_type
杂志文章abstract：:The formation of snow-dirt sludge (SDS) via the mixing of snow and surface-deposited sediment by vehicles and pedestrians is one of the least studied sedimentation processes in urban areas. The aim of this study was to analyse the material, mineral, particle size, and chemical compositions of the SDS solid phase. The ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-53793-z
更新日期：2019-11-21 00:00:00
abstract：:Natural hazards including floods can trigger catastrophic failures in interdependent urban transport network-of-networks (NoNs). Population growth has enhanced transportation demand while urbanization and climate change have intensified urban floods. However, despite the clear need to develop actionable insights for i...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-66049-y
更新日期：2020-06-25 00:00:00
abstract：:The anisotropic transport of thermal neutron in heterogeneous porous media is of great research interests in many fields. In this paper, it is the first time that a new model based on micron X-ray computed tomography (CT) has been proposed to simultaneously consider both the separation of matrix and pore and the distr...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep27488
更新日期：2016-06-08 00:00:00
abstract：:To increase the energy storage density of lithium-ion batteries, silicon anodes have been explored due to their high capacity. One of the main challenges for silicon anodes are large volume variations during the lithiation processes. Recently, several high-performance schemes have been demonstrated with increased life...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-51087-y
更新日期：2019-10-10 00:00:00
abstract：:This paper reports the fabrication and operation of a transmission-type polarization rotator for visible light with a wavelength of 450 nm using indirect-transition-type semiconductor crystalline SiC in which Al atoms were implanted as a p-type dopant. A novel dressed-photon-phonon (DPP)-assisted annealing method was ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-69971-3
更新日期：2020-07-31 00:00:00
abstract：:Seed setting is an important trait that contributes to seed yield and relies greatly on starch accumulation. In this study, a sulfoquinovosyl transferase-like protein, designated as SQD2.2 involved in seed setting and flavonoid accumulation, was identified and characterized in rice. Rice SQD2.2 is localized to the cyt...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-04002-2
更新日期：2017-07-05 00:00:00
abstract：:Here we developed an orange light-absorbing chromoprotein named ShadowR as a novel acceptor for performing fluorescence lifetime imaging microscopy-based Förster resonance energy transfer (FLIM-FRET) measurement in living cells. ShadowR was generated by replacing hydrophobic amino acids located at the surface of the c...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-48604-4
更新日期：2019-08-19 00:00:00
abstract：:Calcification is important for the diagnosis of papillary thyroid carcinoma (PTC). Runt-related transcription factor 2 (RUNX2), a master transcription factor associated with osteogenic differentiation, is reportedly related to PTC calcification and invasiveness. However, its regulatory role in this process is somewhat...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-43207-5
更新日期：2019-05-01 00:00:00
abstract：:Voltage-gated sodium (NaV) channels have been related with cell migration and invasiveness in human cancers. We previously reported the contribution of NaV1.6 channels activity with the invasion capacity of cervical cancer (CeCa) positive to Human Papilloma Virus type 16 (HPV16), which accounts for 50% of all CeCa cas...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-31364-y
更新日期：2018-08-29 00:00:00
abstract：:The analysis of DNA methylation at CpG dinucleotides has become a major research focus due to its regulatory role in numerous biological processes, but the requisite need for assays which amplify bisulfite-converted DNA represents a major bottleneck due to the unique design constraints imposed on bisulfite-PCR primers...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep41328
更新日期：2017-01-24 00:00:00
abstract：:There is an urgent need for sensors deployed during focal therapies to inform treatment planning and in vivo monitoring in thin tissues. Specifically, the measurement of thermal properties, cooling surface contact, tissue thickness, blood flow and phase change with mm to sub mm accuracy are needed. As a proof of princ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep21395
更新日期：2016-02-26 00:00:00
abstract：:Relativistic electron rings hold the possibility of very high accelerating rates, and hopefully a relatively cheap and compact accelerator/collimator for ultrahigh energy proton source. In this work, we investigate the generation of helical shaped quasi-monoenergetic relativistic electron beam and high-energy proton b...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-20506-x
更新日期：2018-02-01 00:00:00
abstract：:Microfluidic paper-based analytical devices (µPADs) have provided a breakthrough in portable and low-cost point-of-care diagnostics. Despite their significant scope, the complexity of fabrication and reliance on expensive and sophisticated tools, have limited their outreach and possibility of commercialization. Herein...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-44455-1
更新日期：2019-05-27 00:00:00
abstract：:Skyrmions in ultrathin ferromagnetic metal (FM)/heavy metal (HM) multilayer systems produced by conventional sputtering methods have recently generated huge interest due to their applications in the field of spintronics. The sandwich structure with two correctly-chosen heavy metal layers provides an additive interfaci...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-23799-0
更新日期：2018-04-09 00:00:00
abstract：:Dynamic optical imaging (e.g. time delay integration imaging) is troubled by the motion blur fundamentally arising from mismatching between photo-induced charge transfer and optical image movements. Motion aberrations from the forward dynamic imaging link impede the acquiring of high-quality images. Here, we propose a...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-47564-z
更新日期：2019-08-05 00:00:00
abstract：:Antidiabetic medication may modify the incidence of hepatocellular carcinoma (HCC). We aimed to compare the use of different antidiabetic strategies and the incidence of HCC. PubMed, Embase.com and Cochrane Library databases were searched up to 31 October 2015 and randomized controlled trials (RCTs), cohort studies or...
journal_title：Scientific reports
pub_type： 杂志文章,meta分析,评审
doi：10.1038/srep33743
更新日期：2016-09-19 00:00:00
abstract：:We have performed a genome-wide association study (GWAS) including 473 Japanese HBV (hepatitis B virus)-positive HCC (hepatocellular carcinoma) patients and 516 HBV carriers including chronic hepatitis and asymptomatic carrier individuals to identify new host genetic factors associated with HBV-derived HCC in Japanese...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-26217-7
更新日期：2018-05-21 00:00:00
abstract：:c-Jun N-terminal kinase (JNK) is a member of the mitogen-activated protein kinase family and controls various physiological processes including apoptosis. A specific upstream activator of JNKs is the mitogen-activated protein kinase kinase 7 (MKK7). It has been reported that MKK7-JNK signaling plays an important regul...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-07845-x
更新日期：2017-08-04 00:00:00
abstract：:Older patients, especially those with malignancy, may have an increased risk of pulmonary embolism (PE). However, few studies have evaluated the clinical characteristics and prognosis of older patients. We evaluated the clinical characteristics, prognosis, and risk factors in older patients with lung cancer complicate...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-58345-4
更新日期：2020-01-27 00:00:00
abstract：:The widespread use of electric light and electronic devices has resulted in an excessive exposure to light during the late-evening and at night. This late light exposure acutely suppresses melatonin and sleepiness and delays the circadian clock. Here we investigate whether the acute effects of late-evening light expos...
journal_title：Scientific reports
pub_type： 杂志文章,随机对照试验
doi：10.1038/s41598-019-52352-w
更新日期：2019-11-05 00:00:00
abstract：:The clinical application of dihydroartemisinin (DHA) has been hampered due to its poor water-solubility. To overcome this hurdle, we devised a novel polymer-drug conjugate, multiarm polyethylene glycol-dihydroartemisinin (PEG-DHA), made by linking DHA with multiarm polyethylene glycol. Herein, we investigated PEG-DHA ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep05871
更新日期：2014-07-29 00:00:00
abstract：:Long-branch attraction (LBA) is a major obstacle in phylogenetic reconstruction. The phylogenetic relationships among Juniperus (J), Cupressus (C) and the Hesperocyparis-Callitropsis-Xanthocyparis (HCX) subclades of Cupressoideae are controversial. Our initial analyses of plastid protein-coding gene matrix revealed bo...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep41005
更新日期：2017-01-25 00:00:00
abstract：:Both genetic and environmental factors are suggested to influence overweight and obesity risks. Although individual loci and genes have been frequently shown to be associated with body mass index (BMI), the overall interaction of these genes and their role in BMI remains underexplored. Data were collected in 90 health...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-43881-5
更新日期：2019-05-15 00:00:00
abstract：:Fibulins are extracellular matrix proteins associated with elastic fibres. Homozygous Fibulin-4 mutations lead to life-threatening abnormalities such as aortic aneurysms. Aortic aneurysms in Fibulin-4 mutant mice were associated with upregulation of TGF-β signalling. How Fibulin-4 deficiency leads to deregulation of t...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep16872
更新日期：2015-11-26 00:00:00
abstract：:Selective inhibition of function-specific β-GlcNAcase has great potential in terms of drug design and biological research. The symmetrical bis-naphthalimide M-31850 was previously obtained by screening for specificity against human glycoconjugate-lytic β-GlcNAcase. Using protein-ligand co-crystallization and molecular...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep06188
更新日期：2014-08-26 00:00:00
abstract：:There is a pressing need for novel and innovative therapeutic strategies to address infections caused by intracellular pathogens. Peptide nucleic acids (PNAs) present a novel method to target intracellular pathogens due to their unique mechanism of action and their ability to be conjugated to cell penetrating peptides...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep20832
更新日期：2016-02-10 00:00:00
abstract：:Atherosclerotic arteries exhibit characteristic constrictions and substantial deviations from cylindrical shape. Therefore, determining the artery's cross-section along the centerline is challenging, although high-resolution isotropic three-dimensional data are available. Herein, we apply high-resolution computed tomo...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-50711-1
更新日期：2019-10-04 00:00:00
abstract：:We employed an RNA-guided CRISPR/Cas9 DNA editing system to precisely remove the entire HIV-1 genome spanning between 5' and 3' LTRs of integrated HIV-1 proviral DNA copies from latently infected human CD4+ T-cells. Comprehensive assessment of whole-genome sequencing of HIV-1 eradicated cells ruled out any off-target ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep22555
更新日期：2016-03-04 00:00:00
abstract：:We report the counterintuitive mechanism of increasing boiling heat transfer by incorporating low-conductivity materials at the interface between the surface and fluid. By embedding an array of non-conductive lines into a high-conductivity substrate, in-plane variations in the local surface temperature are created. Du...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep13145
更新日期：2015-08-18 00:00:00
abstract：:Targeting cancer-associated fibroblasts (CAFs), as well as the crosstalk between stroma and cancer cells, could be of value in managing cancers. Pirfenidone (PFD) is an anti-fibrotic agent for idiopathic pulmonary fibrosis. This study aimed to investigate the possibility that PFD might exert an anti-tumor effect throu...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-67904-8
更新日期：2020-07-02 00:00:00
