Abstract:
RATIONALE AND OBJECTIVES:Cardiovascular (CV) disease is predominately influenced by CV risk factors and coronary computed tomography angiography (CTA) is capable of detecting early-stage coronary artery disease. We sought to determine the influence of CV risk factors on the prevalence of nonobstructive atherosclerosis in patients with normal-appearing coronary arteries in invasive coronary angiography (ICA). MATERIALS AND METHODS:In this retrospective analysis, we included 60 consecutive symptomatic patients, having undergone ICA and coronary CTA. Coronary dual source CTA was performed using electrocardiogram-triggered retrospective gated image acquisition at 40%-70% of RR interval (tube voltage 100-120 kV, tube current time product 320-440 mAs, 60 mL contrast, and flow rate 6 mL/s). RESULTS:Out of 60 patients (32 men, mean age 61 ± 11 years) with a normal coronary artery appearance in ICA, 45 (75%) patients showed atherosclerotic plaque in CTA. Plaque was present in 14 of 60 (23%) left main, 41 of 60 (68%) left anterior descending, 21 of 60 (35%) circumflex coronary arteries, and 24 of 60 (40%) right coronary arteries. More than 15% of all coronary artery segments showed detectable plaques. Interobserver agreement ranged from good to very good on a per-patient, per-vessel, and per-segment level. Patients with presence of plaque were significantly older (P = 0.005) and showed higher incidence of arterial hypertension (P = 0.019) as compared to individuals without coronary plaque in dual source computed tomography. CONCLUSIONS:The prevalence of coronary atherosclerosis by CTA is substantial in symptomatic patients with normal invasive coronary angiogram. Hypertension and older age significantly influence the prevalence of atherosclerotic plaque and highlight the importance of risk-modifying therapy.
journal_name
Acad Radioljournal_title
Academic radiologyauthors
Bittner DO,Klinghammer L,Marwan M,Schmid J,Layritz C,Hoffmann U,Achenbach S,Pflederer Tdoi
10.1016/j.acra.2016.12.005subject
Has Abstractpub_date
2017-05-01 00:00:00pages
580-586issue
5eissn
1076-6332issn
1878-4046pii
S1076-6332(17)30006-5journal_volume
24pub_type
杂志文章abstract:RATIONALE AND OBJECTIVES:This study's aims were to depict changes in cartilage quality after surgical intervention using magnetic resonance (MR) examination and in content of glycosaminoglycans chains (GAGs) after two types of surgeries - chondral defect treatment by microfractures and scaffold implantation in combinat...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2020.05.030
更新日期:2020-06-30 00:00:00
abstract::Computer-aided detection (CADe) and computer-aided diagnosis (CADx) have been important areas of research in the last two decades. Significant progress has been made in the area of breast cancer detection, and CAD techniques are being developed in many other areas. Recent advances in multidetector row computed tomogra...
journal_title:Academic radiology
pub_type: 杂志文章,评审
doi:10.1016/j.acra.2008.01.014
更新日期:2008-05-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Severe calcifications of the coronary arteries are still a major challenge in coronary computed tomography (CT) angiography (CCTA). Subtraction CCTA using a 320-detector row CT scanner has recently been introduced for patients with severe calcifications. However, the conventional subtraction CC...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2016.04.012
更新日期:2016-09-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:The authors evaluated the diagnostic accuracy of viewing computed tomographic (CT) scans as film versus soft-copy images at a workstation. METHODS:Receiver operating characteristic analysis of the interpretation of 202 CT scans (103 were normal, 99 were abnormal) by five neuroradiologists was ...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/s1076-6332(97)80004-9
更新日期:1997-02-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Histological subtypes of lung cancers are critical for clinical treatment decision. In this study, we attempt to use 3D deep learning and radiomics methods to automatically distinguish lung adenocarcinomas (ADC), squamous cell carcinomas (SCC), and small cell lung cancers (SCLC) respectively on...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2020.06.010
更新日期:2020-07-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:HER-2/neu is a valuable prognostic and therapeutic marker in primary breast carcinoma. The objective of this study was to determine the mammographic and patient characteristics (age) that correlate with HER-2/neu overexpression in primary breast carcinoma. MATERIALS AND METHODS:HER-2/neu chara...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2006.06.015
更新日期:2006-10-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:To investigate the feasibility of oxygen-challenge blood oxygen level-dependent (BOLD) magnetic resonance imaging (MRI) at 3T for evaluating the early change of blood oxygenation before and after transcatheter arterial embolization (TACE) in patients with hepatocellular carcinoma (HCC). MATERI...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2020.06.021
更新日期:2020-07-31 00:00:00
abstract:RATIONALE AND OBJECTIVES:Cellulitis is a common cause for emergency department (ED) presentation and subsequent hospital admission. Underlying fracture, osteomyelitis, or foreign body is often considered in the clinical evaluation of these patients. Accordingly, plain radiographs (XRs) of the affected extremity are oft...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2015.08.002
更新日期:2015-11-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:To demonstrate that a massive training artificial neural network (MTANN) can be adequately trained with a small number of cases in the distinction between nodules and vessels (non-nodules) in thoracic computed tomography (CT) images. MATERIALS AND METHODS:An MTANN is a trainable, highly nonlin...
journal_title:Academic radiology
pub_type: 临床试验,杂志文章
doi:10.1016/j.acra.2005.06.017
更新日期:2005-10-01 00:00:00
abstract::Quantitative imaging (QI) is increasingly applied in modern radiology practice, assisting in the clinical assessment of many patients and providing a source of biomarkers for a spectrum of diseases. QI is commonly used to inform patient diagnosis or prognosis, determine the choice of therapy, or monitor therapy respon...
journal_title:Academic radiology
pub_type: 杂志文章,评审
doi:10.1016/j.acra.2014.08.011
更新日期:2015-01-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:The aim of this study was to retrospectively evaluate an automated global scoring system for evaluating the extent and severity of disease in a known cohort of patients with documented bronchiectasis. On the basis of a combination of validated three-dimensional automated algorithms for bronchia...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2010.04.019
更新日期:2010-09-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:The aim of this study was to assess if graphical user interface screen-capture software applied to a magnetic resonance (MR) hardware console could nonintrusively allow the analysis of discrepancies between expected and experienced MR table time. MATERIALS AND METHODS:Individual MR examination...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2009.05.009
更新日期:2009-10-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:A number of studies have reported decreases in fractional anistropy (FA) in amyotrophic lateral sclerosis using diffusion tensor imaging (DTI). The purpose of this study was to perform a meta-analysis in order to estimate the diagnostic test accuracy measures of DTI for the diagnosis of amyotro...
journal_title:Academic radiology
pub_type: 杂志文章,meta分析
doi:10.1016/j.acra.2012.04.012
更新日期:2012-09-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:The purpose of this study was to evaluate our preliminary experience with routine contrast-enhanced magnetic resonance angiography (CE-MRA) of the lower limb arteries in patients with end-stage renal failure. MATERIALS AND METHODS:A retrospective analysis was performed on clinical, physiologic...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2005.01.021
更新日期:2005-05-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Early loss of a sensory modality has been associated with cortical reorganization in both animal models and humans. The purpose of this study was to map visual activation with functional magnetic resonance (MR) imaging and to document possible developmental reorganization in the temporal lobe c...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/S1076-6332(03)80684-0
更新日期:2001-07-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:The purpose of this study was to identify radiology topics considered essential by residency program directors who will be working with our graduates. Secondary goals were to survey their satisfaction with incoming residents' radiology knowledge, inquire if radiology training was provided in th...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2012.12.003
更新日期:2013-03-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Balloon dilatation is a mechanical form of controlled injury used to alleviate vascular stenoses. Several factors influence successful angioplasty. Few mechanical models exist to illustrate the physical principles of balloon dilatation. METHODS:We used mechanical analysis of membrane stresses,...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/s1076-6332(05)80340-x
更新日期:1995-05-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:The aim of this study was to develop a pulmonary nodule viewing system to visualize and retrieve data from the Lung Image Database Consortium. MATERIALS AND METHODS:The pulmonary nodule viewing system, developed using Microsoft C++ and the .NET 2.0 Framework, is composed of a clinical informat...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2011.04.006
更新日期:2011-09-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:The authors performed this study to determine whether intrathoracic inoculation of non-small-cell lung carcinoma with fluoroscopic guidance would provide for more accurate implantation. MATERIALS AND METHODS:A tumor cell inoculum (2 x 10(6) cells per 0.15 mL) was injected percutaneously under ...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/s1076-6332(05)80267-3
更新日期:1997-09-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Manganese is a well-known liver-specific agent used in magnetic resonance imaging. For this purpose, manganese is now administered intravenously. In theory it should be possible to increase the gastrointestinal uptake of manganese through the use of nutritional products as promoters. Such an ag...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/s1076-6332(03)00571-3
更新日期:2004-01-01 00:00:00
abstract:BACKGROUND:There is compelling evidence that neurochemical changes measured by proton magnetic resonance spectroscopy (1H-MRS) occur at different phases of Alzheimer's disease (AD). However, the extent to which these neurochemical changes are associated with validated AD biomarkers and/or apolipoprotein (APOE) ε4 is ye...
journal_title:Academic radiology
pub_type: 杂志文章,评审
doi:10.1016/j.acra.2020.06.006
更新日期:2020-07-07 00:00:00
abstract::This case study chronicles the impact of Hurricane Katrina on the Department of Radiology at the Louisiana State University School of Medicine in New Orleans and the department's subsequent efforts to recover and re-dedicate itself to providing quality patient care and resident education. Hurricane Katrina damaged the...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2009.01.016
更新日期:2009-05-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:To noninvasively estimate the severity of liver fibrosis using perfusion-CT (PCT)-based quantification of dual liver blood supply prior to liver transplantation or liver resections and to correlate results with histological grading of fibrosis stages and AST-platelet ratio index. MATERIALS AND...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2018.11.009
更新日期:2019-09-01 00:00:00
abstract::At our institution, we have developed a remediation team of strong, focused experts who help us with struggling learners in making the diagnosis and then coaching on their milestone deficits. It is key for all program directors to recognize struggling residents because early recognition and intervention gives the resi...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2016.12.022
更新日期:2017-06-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Digitizing images for use in case presentations based on hardcopy films, slides, photographs, negatives, books, and videos can present a challenging task. Scanners and digital cameras have become standard tools of the trade. Unfortunately, use of these devices to digitize multiple images in man...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/s1076-6332(03)00010-2
更新日期:2003-08-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:The aim of this study was to determine the optimal arterial phase delay for computed tomography imaging of hepatocellular carcinoma (HCC) before and after transarterial chemoembolization (TACE) using a low iodine dose protocol. MATERIALS AND METHODS:A total of 39 patients with known HCC were i...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2015.08.021
更新日期:2015-12-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:In our earlier studies, we reported an evidence-based computer-assisted decision (CAD) system for location-specific interrogation of mammograms. A content-based image retrieval framework with information theoretic (IT) similarity measures serves as the foundation for this system. Specifically, ...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2007.12.013
更新日期:2008-05-01 00:00:00
abstract:RATIONALE AND OBJECTIVE:The advantage of a higher static magnetic field for functional MRI has been advocated; however, the observed advantage varies. The aim of this study was to evaluate the effect of increasing static magnetic field strength on the task-related increase in blood oxygenation level-dependent (BOLD) si...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2004.11.012
更新日期:2005-02-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:A survey was administered to fourth-year radiology residents after receiving their results from the first American Board of Radiology (ABR) Core examination in 2013. The purpose was to gather information regarding resources and study strategies to share with program directors and future residen...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2014.07.026
更新日期:2015-01-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:The aim of this study was to compare the performance of various image-based metrics computed from thoracic high-resolution computed tomography (HRCT) with data from pulmonary function testing (PFT) in characterizing interstitial lung disease (ILD) and chronic obstructive pulmonary disease (COPD...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2012.03.007
更新日期:2012-07-01 00:00:00