Optimization of the Epithermal Neutron Beam for Boron Neutron Capture Therapy at the Brookhaven Medical Research Reactor.

Abstract:

:The use of epithermal neutron beam in clinical trials of Boron Neutron Capture Therapy for patients with malignant brain tumors had been carried out for half a decade at the Brookhaven's Medical Reactor. The decision to permanently close this reactor in 2000 cut short the efforts to implement a new conceptual design to optimize this beam in preparation for use with possible new BNCT protocols. Details of the conceptual design to produce a highly intensified and focused neutron beam with less gamma and neutron contamination in tissues are presented here for their potential applicability to other reactor facilities. Neutron-photon coupled Monte Carlo calculations were used to predict the flux, current, heating, and absorbed dose produced by the proposed design. The results were benchmarked by the dose rate and flux measurements taken at the facility then in use.

journal_name

Health Phys

journal_title

Health physics

authors

Hu JP,Reciniello RN,Holden NE

subject

Has Abstract

pub_date

2004-05-01 00:00:00

pages

S103-S109

eissn

0017-9078

issn

1538-5159

pii

00004032-200405002-00013

journal_volume

86 Suppl 2

pub_type

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