Estimation of human gonadal Pu and Ce concentrations from animal data.

Abstract:

:Data were obtained from the literature for gonad and body weights and for the Pu or Ce content of the gonads and body at death for several laboratory animal species, five human Pu injection cases, and 731 human adults exposed environmentally to Pu in fallout. Data for Pu concentration in gonads, liver, and bone samples of 59 male and five female occupational Pu cases (including four completely analyzed whole bodies) were obtained from the U.S. Transuranium Registry. A logarithmic function was used to relate fractional Pu or Ce concentration in testes and ovaries to body weight of the animals and to predict fractional Pu or Ce concentrations in human gonads, [Pu]G . PuB-1 = aBWb, where [Pu]G or [Ce]G is the nuclide concentration in gonads (Bq g-1 of wet weight), PuB or CeB is the nuclide content of the body at death, and BW is body weight (kg). The fractional Pu and Ce concentrations in both the testes and ovaries are inverse and nearly linear functions of body weight. The regression lines of fractional Pu or Ce concentration in testes and ovaries have similar slopes (b = -1.07 +/- 0.14); however, the nuclide concentrations (coefficient a) in ovaries are six times greater than in testes. Extrapolation of the animal data yielded fractional Pu concentrations in human testes and ovaries that agree with those calculated for the occupational cases and those recommended by the International Commission on Radiological Protection. The good agreement between the fractional concentrations of Pu and Ce in the testes and in the ovaries suggests that these data can be substituted in metabolic models of chemically similar elements for which gonadal data are scarce.

journal_name

Health Phys

journal_title

Health physics

authors

Thomas RG,Durbin PW,McInroy JF,Healy JW

doi

10.1097/00004032-198907001-00012

subject

Has Abstract

pub_date

1989-01-01 00:00:00

pages

97-107

eissn

0017-9078

issn

1538-5159

journal_volume

57 Suppl 1

pub_type

杂志文章
  • Health physics consequences of out-patient treatment of non-Hodgkin's lymphoma with 131I-radiolabeled anti-B1 antibody.

    abstract::The Medical University of South Carolina is currently participating in clinical trials of 131I radiolabeled Anti-B1 antibody for treatment of Non-Hodgkin's lymphoma. Under current South Carolina Department of Health and Environmental Control regulatory guidelines,; these patients are required to be admitted to the hos...

    journal_title:Health physics

    pub_type: 杂志文章

    doi:10.1097/00004032-200011001-00004

    authors: Ryan MT,Spicer KM,Frei-Lahr D,Samei E,Frey GD,Hargrove H,Bloodworth G

    更新日期:2000-11-01 00:00:00

  • Kinetics of fuel particle weathering and 90Sr mobility in the Chernobyl 30-km exclusion zone.

    abstract::Weathering of fuel particles and the subsequent leaching of radionuclides causes 90Sr mobility in Chernobyl soils to increase with time after deposition. Studies of 90Sr speciation in soils collected in 1995 and 1996 from the Chernobyl 30-km exclusion zone have been used to calculate rates of fuel particles dissolutio...

    journal_title:Health physics

    pub_type: 杂志文章

    doi:10.1097/00004032-199903000-00006

    authors: Kashparov VA,Oughton DH,Zvarich SI,Protsak VP,Levchuk SE

    更新日期:1999-03-01 00:00:00

  • Analysis of uranium in drinking water samples using laser induced fluorimetry.

    abstract::Uranium concentration in drinking water samples collected from some areas of Punjab and Himachal Pradesh has been measured using a laser induced fluorimetry technique. The sources of water comprise hand pumps and tube wells. Uranium concentration in the water samples from Punjab varies from 1.39 +/- 0.16 to 98.25 +/- ...

    journal_title:Health physics

    pub_type: 杂志文章

    doi:10.1097/01.HP.0000202233.64500.89

    authors: Rani A,Singh S

    更新日期:2006-08-01 00:00:00

  • Uptake of 244Cm, 238Pu and other radionuclides by trees inhabiting a contaminated flood plain.

    abstract::The plant uptake of 244Cm, 137Cs, 238Pu and 90Sr was measured for trees in a flood plain forest whose soils were contaminated by aqueous discharges from a nuclear-fuel chemical separations facility. Uptake of the naturally occurring radionuclide 226Ra was also measured. The relative availability of the nuclides was 23...

    journal_title:Health physics

    pub_type: 杂志文章

    doi:10.1097/00004032-198409000-00003

    authors: Pinder JE 3rd,McLeod KW,Alberts JJ,Adriano DC,Corey JC

    更新日期:1984-09-01 00:00:00

  • The distribution of Thorotrast in human bone marrow: a case report.

    abstract::Samples of bone containing cellular and fatty bone marrow were removed at autopsy from the body of a woman who, following an automobile accident, had been injected with approximately 25 mL of the radiographic contrast medium Thorotrast. The woman survived for 36 y after the accident and died at age 72 y following bone...

    journal_title:Health physics

    pub_type: 杂志文章

    doi:10.1097/00004032-199207000-00007

    authors: Priest ND,Humphreys JA,Kathren RL,Mays CW

    更新日期:1992-07-01 00:00:00

  • Significance of contaminated food in collective dose after a severe reactor accident.

    abstract::The importance of the ingestion dose pathways in collective effective dose due to severe reactor accidents is evaluated by studying two different radioactive accidental releases. A short description of the ingestion dose pathway model is also given. Typically, exposure via contaminated food without countermeasures cau...

    journal_title:Health physics

    pub_type: 杂志文章

    doi:10.1097/00004032-198602000-00004

    authors: Partanen JP,Savolainen I

    更新日期:1986-02-01 00:00:00

  • Developments in Biodosimetry Methods for Triage With a Focus on X-band Electron Paramagnetic Resonance In Vivo Fingernail Dosimetry.

    abstract::Instrumentation and application methodologies for rapidly and accurately estimating individual ionizing radiation dose are needed for on-site triage in a radiological/nuclear event. One such methodology is an in vivo X-band, electron paramagnetic resonance, physically based dosimetry method to directly measure the rad...

    journal_title:Health physics

    pub_type: 杂志文章

    doi:10.1097/HP.0000000000000874

    authors: Swarts SG,Sidabras JW,Grinberg O,Tipikin DS,Kmiec MM,Petryakov SV,Schreiber W,Wood VA,Williams BB,Flood AB,Swartz HM

    更新日期:2018-07-01 00:00:00

  • Operational radiation safety for PET-CT, SPECT-CT, and cyclotron facilities.

    abstract::Positron emission tomography (PET) and single-photon emission computed tomography (SPECT) are well- established and indispensable imaging modalities in modern medicine. State-of-the-art computed tomography (CT) scanners have now been integrated into multi-modality PET-CT and SPECT-CT devices, and these devices, partic...

    journal_title:Health physics

    pub_type: 杂志文章

    doi:10.1097/01.HP.0000327651.15794.f7

    authors: Zanzonico P,Dauer L,St Germain J

    更新日期:2008-11-01 00:00:00

  • An evaluation of the BD-100R rechargeable neutron bubble dosimeter.

    abstract::The purpose of this paper is to present data gathered in the evaluation of the BD-100R neutron bubble dosimeter done at the University of Maryland and the Naval Research Lab. The performance of 12 dosimeters has been followed over 15 exposure-recharge cycles under a wide range of exposure conditions. Included in this ...

    journal_title:Health physics

    pub_type: 杂志文章

    doi:10.1097/00004032-199103000-00007

    authors: Millett M,Munno F,Ebert D,Nelson M

    更新日期:1991-03-01 00:00:00

  • An electret passive environmental 222Rn monitor based on ionization measurement.

    abstract::The electret passive environmental 222Rn monitor (E-PERM) is an extension of electret dosimeters used for measurement of x and gamma radiation. An E-PERM consists of a small cup or canister, having an electret at the bottom, and a filtered inlet at the top. The 222Rn gas entering through the filter and the decay produ...

    journal_title:Health physics

    pub_type: 杂志文章

    doi:10.1097/00004032-198801000-00002

    authors: Kotrappa P,Dempsey JC,Hickey JR,Stieff LR

    更新日期:1988-01-01 00:00:00

  • Mitigating radiation-induced toxicity: an overview of new approaches developed at the French Military Biomedical Research Institute.

    abstract::Acute radiation syndrome represents the clinical response of radiation-sensitive key tissues (i.e., hematopoietic, gastrointestinal and neurovascular) following exposure to high doses of ionizing radiation. In this context, the hematopoietic syndrome remains the first therapeutic challenge. Today, identifying new drug...

    journal_title:Health physics

    pub_type: 杂志文章,评审

    doi:10.1097/HP.0000000000000039

    authors: Drouet M,Hérodin F

    更新日期:2014-06-01 00:00:00

  • Radionuclides in the terrestrial ecosystem near a Canadian uranium mill--Part I: Distribution and doses.

    abstract::Soils, vegetation, small mammals, and birds were measured for uranium series radionuclides at three sites near the operating Key Lake uranium mill in northern Saskatchewan. Sites, impacted by windblown tailings and mill dust, had significantly higher concentrations of uranium, 226Ra, 210Pb, and 210Po in soils, litter,...

    journal_title:Health physics

    pub_type: 杂志文章

    doi:10.1097/00004032-200006000-00003

    authors: Thomas PA

    更新日期:2000-06-01 00:00:00

  • Cancer mortality around La Hague nuclear facilities.

    abstract::Cancer death rates from the Beaumont-Hague "canton," where a nuclear facility is located, were compared with those for the Manche "département." No significant increase was found in cancer deaths during 1970-1982 for leukemias and in 1975-1982 for all other types of malignant tumors. ...

    journal_title:Health physics

    pub_type: 杂志文章

    doi:10.1097/00004032-198906000-00005

    authors: Dousset M

    更新日期:1989-06-01 00:00:00

  • Is knowledge important? Empirical research on nuclear risk communication in two countries.

    abstract::Increasing audience knowledge is often set as a primary objective of risk communication efforts. But is it worthwhile focusing risk communication strategies solely on enhancing specific knowledge? The main research questions tackled in this paper were: (1) if prior audience knowledge related to specific radiation risk...

    journal_title:Health physics

    pub_type: 杂志文章

    doi:10.1097/HP.0b013e31823fb5a5

    authors: Perko T,Zeleznik N,Turcanu C,Thijssen P

    更新日期:2012-06-01 00:00:00

  • The delayed pulmonary syndrome following acute high-dose irradiation: a rhesus macaque model.

    abstract::Several radiation dose- and time-dependent tissue sequelae develop following acute high-dose radiation exposure. One of the recognized delayed effects of such exposures is lung injury, characterized by respiratory failure as a result of pneumonitis that may subsequently develop into lung fibrosis. Since this pulmonary...

    journal_title:Health physics

    pub_type: 杂志文章

    doi:10.1097/HP.0b013e3182a32b3f

    authors: Garofalo M,Bennett A,Farese AM,Harper J,Ward A,Taylor-Howell C,Cui W,Gibbs A,Lasio G,Jackson W 3rd,MacVittie TJ

    更新日期:2014-01-01 00:00:00

  • A review of countermeasures to reduce radioiodine in milk of dairy animals.

    abstract::The most effective countermeasure for radioiodine contamination of milk is to provide dairy animals with uncontaminated feed, with the added advantage that it will be effective for other radionuclides in the fallout. Another effective response is to process the milk into storable dairy products for an appropriate leng...

    journal_title:Health physics

    pub_type: 杂志文章

    doi:10.1097/00004032-199611000-00005

    authors: Howard BJ,Voigt G,Segal MG,Ward GM

    更新日期:1996-11-01 00:00:00

  • Criteria for the administration of KI for thyroid blocking of radioiodine.

    abstract::Scientific data are reviewed to evaluate the risks of radioiodine uptake and to compare those risks with the benefits and risks of low milligram doses of stable potassium iodide (KI). The limit of 25 rad to the thyroid due to radioiodine uptake is adopted as the "break-even" point above which 130-mg KI doses should be...

    journal_title:Health physics

    pub_type: 杂志文章,评审

    doi:10.1097/00004032-198502000-00001

    authors: Meck RA,Chen MS,Kenny PJ

    更新日期:1985-02-01 00:00:00

  • Measurement of absorbed dose in water irradiated by 2.5-GeV bremsstrahlung.

    abstract::Plane shields made of Pb with a water tank behind them were irradiated by 2.5-GeV bremsstrahlung. The longitudinal distribution of the absorbed dose in water was measured using a scintillation counter. The results are compared with Monte Carlo calculations and published depth dose tables. ...

    journal_title:Health physics

    pub_type: 杂志文章

    doi:10.1097/00004032-198707000-00007

    authors: Ban S,Hirayama H,Miura S

    更新日期:1987-07-01 00:00:00

  • Comparison of U.S. NRC'S Rascal Emergency Response Code with Noaa's Hyrad Dispersion Model and Tracer Experimental Data.

    abstract::The U.S. National Oceanic and Atmospheric Administration's Field Research Division uses the HYRad-HYSPLIT dispersion model to assess hypothetical accidental releases of airborne radioactive materials at the Idaho National Laboratory in southeastern Idaho. The State of Idaho Department of Environmental Quality Idaho Na...

    journal_title:Health physics

    pub_type: 杂志文章

    doi:10.1097/HP.0000000000000907

    authors: Abbott ML

    更新日期:2018-10-01 00:00:00

  • Chernobyl-derived radiocesium in heather honey and its dependence on deposition patterns.

    abstract::Gamma-ray spectra were measured from Scottish heather honey samples gathered from hive locations with associated airborne gamma-ray survey data. The honeys all contained radiocesium, with activity concentrations ranging from 43-680 Bq kg(-1) 137Cs, and 134Cs/137Cs ratios consistent with Chernobyl deposition. Activity ...

    journal_title:Health physics

    pub_type: 杂志文章

    doi:10.1097/00004032-199910000-00011

    authors: Fisk S,Sanderson DC

    更新日期:1999-10-01 00:00:00

  • Methodology for a bounding estimate of activation source-term.

    abstract::Sandia National Laboratories' Z-Machine is the world's most powerful electrical device, and experiments have been conducted that make it the world's most powerful radiation source. Because Z-Machine is used for research, an assortment of materials can be placed into the machine; these materials can be subjected to a r...

    journal_title:Health physics

    pub_type: 杂志文章

    doi:10.1097/HP.0b013e31827126f1

    authors: Culp T

    更新日期:2013-02-01 00:00:00

  • Radiometry and laser safety standards.

    abstract::The application of occupational limits (ELs) in the outdoor laser environment requires an understanding of the radiometric methods required to evaluate field exposures with respect to the ELs. The limiting aperture required to adequately specify the EL must always be kept in mind. Since all exposure limits are defined...

    journal_title:Health physics

    pub_type: 杂志文章

    doi:10.1097/00004032-198905000-00018

    authors: Sliney DH

    更新日期:1989-05-01 00:00:00

  • Effect of Residential Radon Decay Product Dose Factor Variability on Reporting of Dose.

    abstract::Guidelines for occupational exposure to radiation are based on annual absorbed or effective dose. Guidelines for Rn exposure are currently based on air concentrations of Rn or decay products. Models of bronchial dose from decay product exposure are based on calculations that have five major parameters with parameter v...

    journal_title:Health physics

    pub_type: 杂志文章

    doi:10.1097/HP.0000000000000828

    authors: Harley NH

    更新日期:2018-04-01 00:00:00

  • Electromagnetic interference with infusion pumps from GSM mobile phones.

    abstract::Electromagnetic interference with critical medical care devices has been reported by various groups. Previous studies have demonstrated that volumetric and syringe pumps are susceptible to false alarm buzzing and blocking when exposed to various electromagnetic sources. The risk of electromagnetic interference depends...

    journal_title:Health physics

    pub_type: 杂志文章

    doi:10.1097/01.HP.0000183559.25124.5d

    authors: Calcagnini G,Floris M,Censi F,Cianfanelli P,Scavino G,Bartolini P

    更新日期:2006-04-01 00:00:00

  • An environmental radionuclide baseline study near three Canadian naval ports.

    abstract::This paper summarizes an environmental radionuclide baseline study undertaken for the Department of National Defence in Canada. The purpose of the project was to establish levels of radionuclides present in the environment around areas where nuclear propelled vessels may be berthed. Specifically, this report describes...

    journal_title:Health physics

    pub_type: 杂志文章

    doi:10.1097/00004032-199907000-00008

    authors: Waller EJ,Cole D

    更新日期:1999-07-01 00:00:00

  • Metabolism and dosimetry of tritium.

    abstract::This document was prepared as a review of the current knowledge of tritium metabolism and dosimetry. The physical, chemical, and metabolic characteristics of various forms of tritium are presented as they pertain to performing dose assessments for occupational workers and for the general public. For occupational worke...

    journal_title:Health physics

    pub_type: 杂志文章,评审

    doi:10.1097/00004032-199312000-00003

    authors: Hill RL,Johnson JR

    更新日期:1993-12-01 00:00:00

  • Projected Cancer Risks to Residents of New Mexico from Exposure to Trinity Radioactive Fallout.

    abstract::The Trinity nuclear test, conducted in 1945, exposed residents of New Mexico to varying degrees of radioactive fallout. Companion papers in this issue have detailed the results of a dose reconstruction that has estimated tissue-specific radiation absorbed doses to residents of New Mexico from internal and external exp...

    journal_title:Health physics

    pub_type: 杂志文章

    doi:10.1097/HP.0000000000001333

    authors: Cahoon EK,Zhang R,Simon SL,Bouville A,Pfeiffer RM

    更新日期:2020-10-01 00:00:00

  • In vitro dissolution of respirable aerosols of industrial uranium and plutonium mixed-oxide nuclear fuels.

    abstract::Dissolution characteristics of mixed-oxide nuclear fuels are important considerations for prediction of biological behavior of inhaled particles. Four representative industrial mixed-oxide powders were obtained from fuel fabrication enclosures. Studies of the dissolution of Pu, Am and U from aerosol particles of these...

    journal_title:Health physics

    pub_type: 杂志文章

    doi:10.1097/00004032-198312000-00001

    authors: Eidson AF,Mewhinney JA

    更新日期:1983-12-01 00:00:00

  • Analysis of personnel exposures in neutron therapy facilities.

    abstract::In conventional radiation-therapy facilities, radiation doses to medical personnel originate from the leakage radiation of 60Co teletherapy systems or from photoneutrons produced during the operation of x-ray generators at energies over 10 MeV in unsuitably shielded therapy rooms. In neutron-therapy facilities, during...

    journal_title:Health physics

    pub_type: 杂志文章

    doi:10.1097/00004032-198402000-00016

    authors: Rosenberg I,Awschalom M,Ten Haken RK,Bennett BR

    更新日期:1984-02-01 00:00:00

  • Spatial variation of waterborne radon and temporal variation of radon in water at nine Maine schools.

    abstract::Nine elementary schools in Maine were examined to track the release of 222Rn and to determine the transfer coefficient from water into air. Water-use simulations were performed by running sinks and sprayers for 1 h in a kitchen. The 222Rn in air was measured over 24 h throughout the school. The subsequent release of 2...

    journal_title:Health physics

    pub_type: 杂志文章

    doi:10.1097/01.HP.0000251250.62369.89

    authors: Guiseppe VE,Gould TJ,Hess CT

    更新日期:2007-04-01 00:00:00