当前位置： SCI文献检索 > NEUROIMAGE期刊下所有文献 > Investigating resting-state functional connectivity in the cervical spinal cord at 3T.

Investigating resting-state functional connectivity in the cervical spinal cord at 3T.

Abstract：

:The study of spontaneous fluctuations in the blood-oxygen-level-dependent (BOLD) signal has recently been extended from the brain to the spinal cord. Two ultra-high field functional magnetic resonance imaging (fMRI) studies in humans have provided evidence for reproducible resting-state connectivity between the dorsal horns as well as between the ventral horns, and a study in non-human primates has shown that these resting-state signals are impacted by spinal cord injury. As these studies were carried out at ultra-high field strengths using region-of-interest (ROI) based analyses, we investigated whether such resting-state signals could also be observed at the clinically more prevalent field strength of 3T. In a reanalysis of a sample of 20 healthy human participants who underwent a resting-state fMRI acquisition of the cervical spinal cord, we were able to observe significant dorsal horn connectivity as well as ventral horn connectivity, but no consistent effects for connectivity between dorsal and ventral horns, thus replicating the human 7T results. These effects were not only observable when averaging along the acquired length of the spinal cord, but also when we examined each of the acquired spinal segments separately, which showed similar patterns of connectivity. Finally, we investigated the robustness of these resting-state signals against variations in the analysis pipeline by varying the type of ROI creation, temporal filtering, nuisance regression and connectivity metric. We observed that - apart from the effects of band-pass filtering - ventral horn connectivity showed excellent robustness, whereas dorsal horn connectivity showed moderate robustness. Together, our results provide evidence that spinal cord resting-state connectivity is a robust and spatially consistent phenomenon that could be a valuable tool for investigating the effects of pathology, disease progression, and treatment response in neurological conditions with a spinal component, such as spinal cord injury.

journal_name

Neuroimage

journal_title

NeuroImage

authors

Eippert F,Kong Y,Winkler AM,Andersson JL,Finsterbusch J,Büchel C,Brooks JCW,Tracey I

doi

10.1016/j.neuroimage.2016.12.072

subject

Has Abstract

pub_date

2017-02-15 00:00:00

pages

589-601

eissn

1053-8119

issn

1095-9572

pii

S1053-8119(16)30798-4

journal_volume

147

pub_type

杂志文章

相关文献

NEUROIMAGE文献大全
  • Lateralization of affective processing in the insula.

    abstract：:Evidence from electrophysiological and functional neuroimaging studies has suggested strong lateralization of affective processing within the insular cortices; however, little is known about the spatial location of these processes in these regions. Using quantitative meta-analytic methods the laterality of: (1) emotio...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2013.04.014

    authors： Duerden EG,Arsalidou M,Lee M,Taylor MJ

    更新日期：2013-09-01 00:00:00

  • Problem solving, working memory, and motor correlates of association and commissural fiber bundles in normal aging: a quantitative fiber tracking study.

    abstract：:Normal aging is accompanied by decline in selective cognitive and motor functions. A concurrent decline in regional white matter integrity, detectable with diffusion tensor imaging (DTI), potentially contributes to waning function. DTI analysis of white matter loci indicates an anterior-to-posterior gradient distribut...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2008.09.046

    authors： Zahr NM,Rohlfing T,Pfefferbaum A,Sullivan EV

    更新日期：2009-02-01 00:00:00

  • Prestimulus alpha power predicts fidelity of sensory encoding in perceptual decision making.

    abstract：:Pre-stimulus α power has been shown to correlate with the behavioral accuracy of perceptual decisions. In most cases, these correlations have been observed by comparing α power for different behavioral outcomes (e.g. correct vs incorrect trials). In this paper we investigate such covariation within the context of beha...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2013.10.041

    authors： Lou B,Li Y,Philiastides MG,Sajda P

    更新日期：2014-02-15 00:00:00

  • The LDA beamformer: Optimal estimation of ERP source time series using linear discriminant analysis.

    abstract：:We introduce a novel beamforming approach for estimating event-related potential (ERP) source time series based on regularized linear discriminant analysis (LDA). The optimization problems in LDA and linearly-constrained minimum-variance (LCMV) beamformers are formally equivalent. The approaches differ in that, in LCM...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2016.01.019

    authors： Treder MS,Porbadnigk AK,Shahbazi Avarvand F,Müller KR,Blankertz B

    更新日期：2016-04-01 00:00:00

  • Brain function and personality in normal males: a SPECT study using statistical parametric mapping.

    abstract：:Understanding the differences between individuals' personality types at a functional brain level is now possible due to recent developments in both functional brain imaging and personality models. The psychobiological model for temperament and character offers one approach to exploring personality. This study uses SPE...

    journal_title：NeuroImage

    pub_type： 临床试验,杂志文章

    doi：10.1016/s1053-8119(03)00171-x

    authors： Turner RM,Hudson IL,Butler PH,Joyce PR

    更新日期：2003-07-01 00:00:00

  • BDNF Val66Met polymorphism tunes frontolimbic circuitry during affective contextual learning.

    abstract：:Adaptive learning impairments are common in cognitive and behavioral disorders, but the neurogenetic mechanisms supporting human affective learning are poorly understood. We designed a higher-order contextual learning task in which healthy participants genotyped for the Val66Met polymorphism of the brain derived neuro...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2017.08.080

    authors： Jabbi M,Cropp B,Nash T,Kohn P,Kippenhan JS,Masdeu JC,Mattay R,Kolachana B,Berman KF

    更新日期：2017-11-15 00:00:00

  • Spatial heterogeneity of the nonlinear dynamics in the FMRI BOLD response.

    abstract：:Recent studies of blood oxygenation level dependent (BOLD) signal responses averaged over a region of interest have demonstrated that the response is nonlinear with respect to stimulus duration. Specifically, shorter duration stimuli produce signal changes larger than expected from a linear system. The focus of this s...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1006/nimg.2001.0873

    authors： Birn RM,Saad ZS,Bandettini PA

    更新日期：2001-10-01 00:00:00

  • Functional plasticity associated with language learning in adults.

    abstract：:Learning a new language in adulthood is increasingly common and among the most difficult tasks attempted by adults. Adult language learners thus offer an excellent window into the nature of learning-dependent plasticity. The present functional magnetic resonance imaging (fMRI) study was aimed at characterising functio...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2019.116040

    authors： Gurunandan K,Carreiras M,Paz-Alonso PM

    更新日期：2019-11-01 00:00:00

  • Sleep sharpens sensory stimulus coding in human visual cortex after fear conditioning.

    abstract：:Efficient perceptual identification of emotionally-relevant stimuli requires optimized neural coding. Because sleep contributes to neural plasticity mechanisms, we asked whether the perceptual representation of emotionally-relevant stimuli within sensory cortices is modified after a period of sleep. We show combined e...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2014.06.003

    authors： Sterpenich V,Piguet C,Desseilles M,Ceravolo L,Gschwind M,Van De Ville D,Vuilleumier P,Schwartz S

    更新日期：2014-10-15 00:00:00

  • Improved determination of the myelin water fraction in human brain using magnetic resonance imaging through Bayesian analysis of mcDESPOT.

    abstract：:Myelin water fraction (MWF) mapping with magnetic resonance imaging has led to the ability to directly observe myelination and demyelination in both the developing brain and in disease. Multicomponent driven equilibrium single pulse observation of T1 and T2 (mcDESPOT) has been proposed as a rapid approach for multicom...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2015.10.034

    authors： Bouhrara M,Spencer RG

    更新日期：2016-02-15 00:00:00

  • Controlling for the effect of arterial-CO2 fluctuations in resting-state fMRI: Comparing end-tidal CO2 clamping and retroactive CO2 correction.

    abstract：:The BOLD signal, as the basis of functional MRI, arises from both neuronal and vascular factors, with their respective contributions to resting state-fMRI still unknown. Among the factors contributing to "physiological noise", dynamic arterial CO2 fluctuations constitutes the strongest and the most widespread modulato...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2020.116874

    authors： Golestani AM,Chen JJ

    更新日期：2020-08-01 00:00:00

  • Event-related fMRI of the auditory cortex.

    abstract：:An event-related protocol was designed to permit auditory fMRI studies minimally affected by the echo-planar noise artifact; a long time interval (TR = 10 s) between each cerebral volume acquisition was combined with stroboscopic data acquisition, and event-related curves were reconstructed with a 1-s resolution. The ...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1006/nimg.1999.0480

    authors： Belin P,Zatorre RJ,Hoge R,Evans AC,Pike B

    更新日期：1999-10-01 00:00:00

  • Age-related changes in reappraisal of appetitive cravings during adolescence.

    abstract：:The ability to regulate temptation and manage appetitive cravings is an important aspect of healthy adolescent development, but the neural systems underlying this process are understudied. In the present study, 60 healthy females evenly distributed from 10 to 23years of age used reappraisal to regulate the desire to c...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2014.12.037

    authors： Giuliani NR,Pfeifer JH

    更新日期：2015-03-01 00:00:00

  • The functional anatomy of single-digit arithmetic in children with developmental dyslexia.

    abstract：:Some arithmetic procedures, such as addition of small numbers, rely on fact retrieval mechanisms supported by left hemisphere perisylvian language areas, while others, such as subtraction, rely on procedural-based mechanisms subserved by bilateral parietal cortices. Previous work suggests that developmental dyslexia, ...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2014.07.028

    authors： Evans TM,Flowers DL,Napoliello EM,Olulade OA,Eden GF

    更新日期：2014-11-01 00:00:00

  • A 4D neonatal head model for diffuse optical imaging of pre-term to term infants.

    abstract：:Diffuse optical tomography is most accurate when an individual's MRI data can be used as a spatial prior for image reconstruction and for visualization of the resulting images of changes in oxy- and deoxy-hemoglobin concentration. As this necessitates an MRI scan to be performed for each study, which undermines many o...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2014.06.028

    authors： Brigadoi S,Aljabar P,Kuklisova-Murgasova M,Arridge SR,Cooper RJ

    更新日期：2014-10-15 00:00:00

  • Gamma-band activity over early sensory areas predicts detection of changes in audiovisual speech stimuli.

    abstract：:Oscillatory activity in the gamma-band range in human magneto- and electroencephalogram is thought to reflect the oscillatory synchronization of cortical networks. Findings of enhanced gamma-band activity (GBA) during cognitive processes like gestalt perception, attention and memory have led to the notion that GBA may...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2005.10.042

    authors： Kaiser J,Hertrich I,Ackermann H,Lutzenberger W

    更新日期：2006-05-01 00:00:00

  • Resting state network estimation in individual subjects.

    abstract：:Resting state functional magnetic resonance imaging (fMRI) has been used to study brain networks associated with both normal and pathological cognitive functions. The objective of this work is to reliably compute resting state network (RSN) topography in single participants. We trained a supervised classifier (multi-l...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2013.05.108

    authors： Hacker CD,Laumann TO,Szrama NP,Baldassarre A,Snyder AZ,Leuthardt EC,Corbetta M

    更新日期：2013-11-15 00:00:00

  • Promise and pitfalls of g-ratio estimation with MRI.

    abstract：:The fiber g-ratio is the ratio of the inner to the outer diameter of the myelin sheath of a myelinated axon. It has a limited dynamic range in healthy white matter, as it is optimized for speed of signal conduction, cellular energetics, and spatial constraints. In vivo imaging of the g-ratio in health and disease woul...

    journal_title：NeuroImage

    pub_type： 杂志文章,评审

    doi：10.1016/j.neuroimage.2017.08.038

    authors： Campbell JSW,Leppert IR,Narayanan S,Boudreau M,Duval T,Cohen-Adad J,Pike GB,Stikov N

    更新日期：2018-11-15 00:00:00

  • Neural mechanisms involved in mental imagery and observation of gait.

    abstract：:Brain activity during observation and imagery of gait was investigated. Sixteen subjects were scanned with a 3-Tesla MRI scanner while viewing six types of video clips: observation of gait movement (GO) from the third-person perspective, observation of stepping movement, observation of standing posture, "virtual walki...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2008.03.010

    authors： Iseki K,Hanakawa T,Shinozaki J,Nankaku M,Fukuyama H

    更新日期：2008-07-01 00:00:00

  • Neuroimaging reveals automatic speech coding during perception of written word meaning.

    abstract：:The extent to which visual word perception engages speech codes (i.e., phonological recoding) remains a crucial question in understanding mechanisms of reading. In this study, we used functional magnetic resonance imaging techniques combined with behavioral response measures to examine neural responses to focused vers...

    journal_title：NeuroImage

    pub_type： 临床试验,杂志文章

    doi：

    authors： Xu B,Grafman J,Gaillard WD,Spanaki M,Ishii K,Balsamo L,Makale M,Theodore WH

    更新日期：2002-10-01 00:00:00

  • Anxiolytic-like effect of pregabalin on unconditioned fear in the rat: an autoradiographic brain perfusion mapping and functional connectivity study.

    abstract：:Clinical and preclinical evidence suggests anxiolytic-like efficacy of pregabalin (PGB, Lyrica). However, its mechanism of action remains under investigation. The current study applied [(14)C]-iodoantipyrine cerebral blood flow (CBF) mapping to examine the effect of PGB on neural substrates underlying unconditioned fe...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2011.11.047

    authors： Wang Z,Pang RD,Hernandez M,Ocampo MA,Holschneider DP

    更新日期：2012-02-15 00:00:00

  • Print-specific multimodal brain activation in kindergarten improves prediction of reading skills in second grade.

    abstract：:Children who are poor readers usually experience troublesome school careers and consequently often suffer from secondary emotional and behavioural problems. Early identification and prediction of later reading problems thus are critical in order to start targeted interventions for those children with an elevated risk ...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2013.05.062

    authors： Bach S,Richardson U,Brandeis D,Martin E,Brem S

    更新日期：2013-11-15 00:00:00

  • Sex-linked association between cortical scene selectivity and navigational ability.

    abstract：:Spatial navigation is a crucial ability for living. Previous studies have shown that males are better at navigation than females, but little is known about the neural basis underlying the sex differences. In this study, we investigated whether cortical scene processing in three well-established scene-selective regions...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2017.07.031

    authors： Kong XZ,Huang Y,Hao X,Hu S,Liu J

    更新日期：2017-09-01 00:00:00

  • Integrating VBM into the General Linear Model with voxelwise anatomical covariates.

    abstract：:A current limitation for imaging of brain function is the potential confound of anatomical differences or registration error, which may manifest via apparent functional "activation" for between-subject analyses. With respect to functional activations, underlying tissue mismatches can be regarded as a nuisance variable...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2006.10.007

    authors： Oakes TR,Fox AS,Johnstone T,Chung MK,Kalin N,Davidson RJ

    更新日期：2007-01-15 00:00:00

  • One season of head-to-ball impact exposure alters functional connectivity in a central autonomic network.

    abstract：:Repetitive head impacts represent a risk factor for neurological impairment in team-sport athletes. In the absence of symptoms, a physiological basis for acute injury has not been elucidated. A basic brain function that is disrupted after mild traumatic brain injury is the regulation of homeostasis, instantiated by ac...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2020.117306

    authors： Monroe DC,Blumenfeld RS,Keator DB,Solodkin A,Small SL

    更新日期：2020-12-01 00:00:00

  • Congruence of happy and sad emotion in music and faces modifies cortical audiovisual activation.

    abstract：BACKGROUND:The powerful emotion inducing properties of music are well-known, yet music may convey differing emotional responses depending on environmental factors. We hypothesized that neural mechanisms involved in listening to music may differ when presented together with visual stimuli that conveyed the same emotion ...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2010.11.017

    authors： Jeong JW,Diwadkar VA,Chugani CD,Sinsoongsud P,Muzik O,Behen ME,Chugani HT,Chugani DC

    更新日期：2011-02-14 00:00:00

  • Contribution of chronic pain and neuroticism to abnormal forebrain gray matter in patients with temporomandibular disorder.

    abstract：:Cortical plasticity is thought to occur following continuous barrage of nociceptive afferent signals to the brain. Hence, chronic pain is presumed to induce anatomical and physiological changes in the brain over time. Inherent factors, some pre-dating the onset of chronic pain, may also contribute to brain abnormaliti...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2010.12.013

    authors： Moayedi M,Weissman-Fogel I,Crawley AP,Goldberg MB,Freeman BV,Tenenbaum HC,Davis KD

    更新日期：2011-03-01 00:00:00

  • ENIGMA and the individual: Predicting factors that affect the brain in 35 countries worldwide.

    abstract：:In this review, we discuss recent work by the ENIGMA Consortium (http://enigma.ini.usc.edu) - a global alliance of over 500 scientists spread across 200 institutions in 35 countries collectively analyzing brain imaging, clinical, and genetic data. Initially formed to detect genetic influences on brain measures, ENIGMA...

    journal_title：NeuroImage

    pub_type： 杂志文章,评审

    doi：10.1016/j.neuroimage.2015.11.057

    authors： Thompson PM,Andreassen OA,Arias-Vasquez A,Bearden CE,Boedhoe PS,Brouwer RM,Buckner RL,Buitelaar JK,Bulayeva KB,Cannon DM,Cohen RA,Conrod PJ,Dale AM,Deary IJ,Dennis EL,de Reus MA,Desrivieres S,Dima D,Donohoe G,Fisher

    更新日期：2017-01-15 00:00:00

  • Caffeine's effects on cerebrovascular reactivity and coupling between cerebral blood flow and oxygen metabolism.

    abstract：:The blood-oxygenation-level-dependent (BOLD) signal is dependent on multiple physiological factors such as cerebral blood flow (CBF), local oxygen metabolism (CMRO(2)) and cerebral blood volume (CBV). Since caffeine affects both CBF and neural activity, its effects on BOLD remain controversial. The calibrated BOLD app...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2008.09.057

    authors： Chen Y,Parrish TB

    更新日期：2009-02-01 00:00:00

  • Functional specialization of the male insula during taste perception.

    abstract：:The primary gustatory area is located in the insular cortex. Although the insular cortex has been the topic of multiple parcellation studies, its functional specialization regarding taste processing received relatively little attention. Studies investigating the brain response to taste suggested that the insular corte...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2015.06.062

    authors： Dalenberg JR,Hoogeveen HR,Renken RJ,Langers DR,ter Horst GJ

    更新日期：2015-10-01 00:00:00