当前位置： SCI文献检索 > NEUROIMAGE期刊下所有文献 > Problem solving, working memory, and motor correlates of association and commissural fiber bundles in normal aging: a quantitative fiber tracking study.

Problem solving, working memory, and motor correlates of association and commissural fiber bundles in normal aging: a quantitative fiber tracking study.

Abstract：

:Normal aging is accompanied by decline in selective cognitive and motor functions. A concurrent decline in regional white matter integrity, detectable with diffusion tensor imaging (DTI), potentially contributes to waning function. DTI analysis of white matter loci indicates an anterior-to-posterior gradient distribution of declining fractional anisotropy (FA) and increasing diffusivity with age. Quantitative fiber tracking can be used to determine regional patterns of normal aging of fiber systems and test the functional ramifications of the DTI metrics. Here, we used quantitative fiber tracking to examine age effects on commissural (genu and splenium), bilateral association (cingulate, inferior longitudinal fasciculus and uncinate), and fornix fibers in 12 young and 12 elderly healthy men and women and tested functional correlates with concurrent assessment of a wide range of neuropsychological abilities. Principal component analysis of cognitive and motor tests on which the elderly achieved significantly lower scores than the young group was used for data reduction and yielded three factors: Problem Solving, Working Memory, and Motor. Age effects--lower FA or higher diffusivity--in the elderly were prominent in anterior tracts, specifically, genu, fornix, and uncinate fibers. Differential correlations between FA or diffusivity in fiber tracts and scores on Problem Solving, Working Memory, or Motor factors provide convergent validity to the biological meaningfulness of the integrity of the fibers tracked. The observed pattern of relations supports the possibility that regional degradation of white matter fiber integrity is a biological source of age-related functional compromise and may have the potential to limit accessibility to alternative neural systems to compensate for compromised function.

journal_name

Neuroimage

journal_title

NeuroImage

authors

Zahr NM,Rohlfing T,Pfefferbaum A,Sullivan EV

doi

10.1016/j.neuroimage.2008.09.046

subject

Has Abstract

pub_date

2009-02-01 00:00:00

pages

1050-62

issue

3

eissn

1053-8119

issn

1095-9572

pii

S1053-8119(08)01039-2

journal_volume

44

pub_type

杂志文章

相关文献

NEUROIMAGE文献大全
  • Double dissociation between action-driven and perception-driven conflict resolution invoking anterior versus posterior brain systems.

    abstract：:The ability to select and integrate relevant information in the presence of competing irrelevant information can be enhanced by advance information to direct attention and guide response selection. Attentional preparation can reduce perceptual and response conflict, yet little is known about the neural source of confl...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2009.06.058

    authors： Schulte T,Müller-Oehring EM,Vinco S,Hoeft F,Pfefferbaum A,Sullivan EV

    更新日期：2009-11-01 00:00:00

  • Sex-specific, postpuberty changes in mouse brain structures revealed by three-dimensional magnetic resonance microscopy.

    abstract：:Sexual dimorphism of brain structures has been reported in some species. We report that sex-dependent developmental structure changes exist in the C57Bl/6(J) mouse, a common model for the genetic analysis of brain function. High resolution, three-dimensional (3D) magnetic resonance microscopy (MRM) images were obtaine...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2004.03.051

    authors： Koshibu K,Levitt P,Ahrens ET

    更新日期：2004-08-01 00:00:00

  • Differential spatial representation of precision and power grasps in the human motor system.

    abstract：:Power and precision grasps are two interrelated, kinematically distinct types of finger movements. We examined whether these types of motor actions may be spatially differently represented in the human central nervous system. In healthy participants representations of finger movements were mapped by delivering single ...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2017.06.080

    authors： Fricke C,Gentner R,Rumpf JJ,Weise D,Saur D,Classen J

    更新日期：2017-09-01 00:00:00

  • Oxytocin reduces neural activity in the pain circuitry when seeing pain in others.

    abstract：:Our empathetic abilities allow us to feel the pain of others. This phenomenon of vicarious feeling arises because the neural circuitry of feeling pain and seeing pain in others is shared. The neuropeptide oxytocin (OXT) is considered a robust facilitator of empathy, as intranasal OXT studies have repeatedly been shown...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2015.03.049

    authors： Bos PA,Montoya ER,Hermans EJ,Keysers C,van Honk J

    更新日期：2015-06-01 00:00:00

  • Active fibers: matching deformable tract templates to diffusion tensor images.

    abstract：:Reliable quantitative analysis of white matter connectivity in the brain is an open problem in neuroimaging, with common solutions requiring tools for fiber tracking, tractography segmentation and estimation of intersubject correspondence. This paper proposes a novel, template matching approach to the problem. In the ...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2009.01.065

    authors： Eckstein I,Shattuck DW,Stein JL,McMahon KL,de Zubicaray G,Wright MJ,Thompson PM,Toga AW

    更新日期：2009-08-01 00:00:00

  • Joint prediction of longitudinal development of cortical surfaces and white matter fibers from neonatal MRI.

    abstract：:The human brain can be modeled as multiple interrelated shapes (or a multishape), each for characterizing one aspect of the brain, such as the cortex and white matter pathways. Predicting the developing multishape is a very challenging task due to the contrasting nature of the developmental trajectories of the constit...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2017.03.012

    authors： Rekik I,Li G,Yap PT,Chen G,Lin W,Shen D

    更新日期：2017-05-15 00:00:00

  • Synchronization facilitates removal of MRI artefacts from concurrent EEG recordings and increases usable bandwidth.

    abstract：:Investigating human brain function non-invasively by simultaneous EEG and fMRI measurements is gaining in popularity as more and better solutions to the inherent technical challenges emerge. We demonstrate the use of a commercially available frequency divider and phase-locking device for the purpose of synchronizing a...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2006.04.231

    authors： Mandelkow H,Halder P,Boesiger P,Brandeis D

    更新日期：2006-09-01 00:00:00

  • Understanding the functional neuroanatomy of acquired prosopagnosia.

    abstract：:One of the most remarkable disorders following brain damage is prosopagnosia, the inability to recognize faces. While a number of cases of prosopagnosia have been described at the behavioral level, the functional neuroanatomy of this face recognition impairment, and thus the brain regions critically involved in normal...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2006.09.051

    authors： Sorger B,Goebel R,Schiltz C,Rossion B

    更新日期：2007-04-01 00:00:00

  • Interacting sources of interference during sensorimotor integration processes.

    abstract：:Every day, a multitude of interfering sensory inputs needs to be integrated and adequately processed using response selection processes. Interference effects are typically investigated using classical paradigms like the Flanker and Simon task. The sources of interference for Flanker and Simon effect are known to be di...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2015.09.075

    authors： Mückschel M,Stock AK,Dippel G,Chmielewski W,Beste C

    更新日期：2016-01-15 00:00:00

  • Audio-visual synchrony and spatial attention enhance processing of dynamic visual stimulation independently and in parallel: A frequency-tagging study.

    abstract：:The neural processing of a visual stimulus can be facilitated by attending to its position or by a co-occurring auditory tone. Using frequency-tagging, we investigated whether facilitation by spatial attention and audio-visual synchrony rely on similar neural processes. Participants attended to one of two flickering G...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2017.08.022

    authors： Covic A,Keitel C,Porcu E,Schröger E,Müller MM

    更新日期：2017-11-01 00:00:00

  • Imaging brain hemodynamic changes during rat forepaw electrical stimulation using functional photoacoustic microscopy.

    abstract：:The present study reported the development of a novel functional photoacoustic microscopy (fPAM) system for investigating hemodynamic changes in rat cortical vessels associated with electrical forepaw stimulation. Imaging of blood optical absorption by fPAM at multiple appropriately-selected and distinct wavelengths c...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2010.03.065

    authors： Liao LD,Li ML,Lai HY,Shih YY,Lo YC,Tsang S,Chao PC,Lin CT,Jaw FS,Chen YY

    更新日期：2010-08-15 00:00:00

  • Voxel-based morphometry and automated lobar volumetry: the trade-off between spatial scale and statistical correction.

    abstract：:Voxel-based morphometry (VBM) and automated lobar region of interest (ROI) volumetry are comprehensive and fast methods to detect differences in overall brain anatomy on magnetic resonance images. However, VBM and automated lobar ROI volumetry have detected dissimilar gray matter differences within identical image set...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2009.07.018

    authors： Voormolen EH,Wei C,Chow EW,Bassett AS,Mikulis DJ,Crawley AP

    更新日期：2010-01-01 00:00:00

  • Cultural differences in human brain activity: a quantitative meta-analysis.

    abstract：:Psychologists have been trying to understand differences in cognition and behavior between East Asian and Western cultures within a single cognitive framework such as holistic versus analytic or interdependent versus independent processes. However, it remains unclear whether cultural differences in multiple psychologi...

    journal_title：NeuroImage

    pub_type： 杂志文章,meta分析,评审

    doi：10.1016/j.neuroimage.2014.05.062

    authors： Han S,Ma Y

    更新日期：2014-10-01 00:00:00

  • Robust automated constellation-based landmark detection in human brain imaging.

    abstract：:A robust fully automated algorithm for identifying an arbitrary number of landmark points in the human brain is described and validated. The proposed method combines statistical shape models with trained brain morphometric measures to estimate midbrain landmark positions reliably and accurately. Gross morphometric con...

    journal_title：NeuroImage

    pub_type： 杂志文章,评审

    doi：10.1016/j.neuroimage.2017.04.012

    authors： Ghayoor A,Vaidya JG,Johnson HJ

    更新日期：2018-04-15 00:00:00

  • Overlapping brain activity between episodic memory encoding and retrieval: roles of the task-positive and task-negative networks.

    abstract：:The notion that the brain is organized into two complementary networks, one that is task-positive and supports externally-oriented processing, and the other that is task-negative and supports internally-oriented processing, has recently attracted increasing attention. The goal of the present study was to investigate i...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2009.07.058

    authors： Kim H,Daselaar SM,Cabeza R

    更新日期：2010-01-01 00:00:00

  • Temporal decomposition of EEG during a simple reaction time task into stimulus- and response-locked components.

    abstract：:Brain activity during reaction time tasks has been reported to consist of stimulus- and response-locked components. The aim of this study is to apply a method for temporally extracting these components from human scalp electroencephalography (EEG) during an auditory simple reaction time task (SR-task). The stimulus- a...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2007.09.003

    authors： Takeda Y,Yamanaka K,Yamamoto Y

    更新日期：2008-01-15 00:00:00

  • The impact of prior risk experiences on subsequent risky decision-making: the role of the insula.

    abstract：:Risky decision-making is significantly affected by homeostatic states associated with different prior risk experiences, yet the neural mechanisms have not been well understood. Using functional MRI, we examined how gambling decisions and their underlying neural responses were modulated by prior risk experiences, with ...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2009.12.097

    authors： Xue G,Lu Z,Levin IP,Bechara A

    更新日期：2010-04-01 00:00:00

  • Neuroanatomy of adult strabismus: a voxel-based morphometric analysis of magnetic resonance structural scans.

    abstract：:Cerebral deficit has been implicated in the genesis of strabismus and in the mechanisms adopted to compensate for the visual disorder. Voxel-based morphometry (VBM) was applied to magnetic resonance images of strabismic adults to detect any abnormal brain anatomy, which could not be easily identified by simple inspect...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2004.02.021

    authors： Chan ST,Tang KW,Lam KC,Chan LK,Mendola JD,Kwong KK

    更新日期：2004-06-01 00:00:00

  • Anatomically-distinct genetic associations of APOE epsilon4 allele load with regional cortical atrophy in Alzheimer's disease.

    abstract：:APOE epsilon4 is the best-established genetic risk factor for sporadic Alzheimer's disease (AD). However, while homozygotes show greater disease susceptibility and earlier age of onset than heterozygotes, they may not show faster rates of clinical progression. We hypothesize that there are differential APOE epsilon4 a...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2008.10.003

    authors： Filippini N,Rao A,Wetten S,Gibson RA,Borrie M,Guzman D,Kertesz A,Loy-English I,Williams J,Nichols T,Whitcher B,Matthews PM

    更新日期：2009-02-01 00:00:00

  • Expertise for conspecific face individuation in the human brain.

    abstract：:Humans exhibit a marked specialization to process the most experienced facial morphologies. In particular, nonhuman primate faces are poorly discriminated compared to human faces in behavioral tasks. So far however, a clear and consistent marker that quantifies our expertise in human over monkey face discrimination di...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2019.116218

    authors： Damon F,Leleu A,Rekow D,Poncet F,Baudouin JY

    更新日期：2020-01-01 00:00:00

  • Neural circuitry underlying sentence-level linguistic prosody.

    abstract：:This study investigates the neural substrates underlying the perception of two sentence-level prosodic phenomena in Mandarin Chinese: contrastive stress (initial vs. final emphasis position) and intonation (declarative vs. interrogative modality). In an fMRI experiment, Chinese and English listeners were asked to sele...

    journal_title：NeuroImage

    pub_type： 临床试验,杂志文章

    doi：10.1016/j.neuroimage.2005.06.002

    authors： Tong Y,Gandour J,Talavage T,Wong D,Dzemidzic M,Xu Y,Li X,Lowe M

    更新日期：2005-11-01 00:00:00

  • Occipital, parietal, and frontal cortices selectively maintain task-relevant features of multi-feature objects in visual working memory.

    abstract：:Previous studies have shown that information held in visual working memory is represented in the occipital, parietal, and frontal cortices. However, less is known about whether the mnemonic information of multi-feature objects is modulated by task demand in the parietal and frontal regions. To address this question, w...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2017.05.055

    authors： Yu Q,Shim WM

    更新日期：2017-08-15 00:00:00

  • Common neural substrates support speech and non-speech vocal tract gestures.

    abstract：:The issue of whether speech is supported by the same neural substrates as non-speech vocal tract gestures has been contentious. In this fMRI study we tested whether producing non-speech vocal tract gestures in humans shares the same functional neuroanatomy as non-sense speech syllables. Production of non-speech vocal ...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2009.03.032

    authors： Chang SE,Kenney MK,Loucks TM,Poletto CJ,Ludlow CL

    更新日期：2009-08-01 00:00:00

  • Characteristics of respiratory measures in young adults scanned at rest, including systematic changes and "missed" deep breaths.

    abstract：:Breathing rate and depth influence the concentration of carbon dioxide in the blood, altering cerebral blood flow and thus functional magnetic resonance imaging (fMRI) signals. Such respiratory fluctuations can have substantial influence in studies of fMRI signal covariance in subjects at rest, the so-called "resting ...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2019.116234

    authors： Power JD,Lynch CJ,Dubin MJ,Silver BM,Martin A,Jones RM

    更新日期：2020-01-01 00:00:00

  • Optimal spatial regularisation of autocorrelation estimates in fMRI analysis.

    abstract：:In the General Linear Model (GLM) framework for the statistical analysis of fMRI data, the problem of temporal autocorrelations in the residual signal (after regression) has been frequently addressed in the open literature. There exist various methods for correcting the ensuing bias in the statistical testing, among w...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2004.07.048

    authors： Gautama T,Van Hulle MM

    更新日期：2004-11-01 00:00:00

  • Improved determination of the myelin water fraction in human brain using magnetic resonance imaging through Bayesian analysis of mcDESPOT.

    abstract：:Myelin water fraction (MWF) mapping with magnetic resonance imaging has led to the ability to directly observe myelination and demyelination in both the developing brain and in disease. Multicomponent driven equilibrium single pulse observation of T1 and T2 (mcDESPOT) has been proposed as a rapid approach for multicom...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2015.10.034

    authors： Bouhrara M,Spencer RG

    更新日期：2016-02-15 00:00:00

  • Movement-related phase locking in the delta-theta frequency band.

    abstract：:Movements result from a complex interplay of multiple brain regions. These regions are assembled into distinct functional networks depending on the specific properties of the action. However, the nature and details of the dynamics of this complex assembly process are unknown. In this study, we sought to identify key m...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2016.06.052

    authors： Popovych S,Rosjat N,Toth TI,Wang BA,Liu L,Abdollahi RO,Viswanathan S,Grefkes C,Fink GR,Daun S

    更新日期：2016-10-01 00:00:00

  • Widespread affections of large fiber tracts in postoperative temporal lobe epilepsy.

    abstract：:Temporal lobe epilepsy with hippocampus sclerosis (HS) is the most frequent focal epilepsy and often refractory to anticonvulsant therapy. Secondary structural damage has been reported in several studies of temporal lobe epilepsy and unilateral hippocampal sclerosis. Applying diffusion tensor imaging (DTI) we investig...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2009.03.013

    authors： Schoene-Bake JC,Faber J,Trautner P,Kaaden S,Tittgemeyer M,Elger CE,Weber B

    更新日期：2009-07-01 00:00:00

  • How reliable are fMRI-EEG studies of epilepsy? A nonparametric approach to analysis validation and optimization.

    abstract：:Simultaneously acquired functional magnetic resonance imaging (fMRI) and electroencephalography (EEG) data hold great promise for localizing the spatial source of epileptiform events detected in the EEG trace. Despite a number of studies applying this method, there has been no independent and systematic validation of ...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2004.09.005

    authors： Waites AB,Shaw ME,Briellmann RS,Labate A,Abbott DF,Jackson GD

    更新日期：2005-01-01 00:00:00

  • Event-related fMRI of the auditory cortex.

    abstract：:An event-related protocol was designed to permit auditory fMRI studies minimally affected by the echo-planar noise artifact; a long time interval (TR = 10 s) between each cerebral volume acquisition was combined with stroboscopic data acquisition, and event-related curves were reconstructed with a 1-s resolution. The ...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1006/nimg.1999.0480

    authors： Belin P,Zatorre RJ,Hoge R,Evans AC,Pike B

    更新日期：1999-10-01 00:00:00