Abstract:
:Reliable quantitative analysis of white matter connectivity in the brain is an open problem in neuroimaging, with common solutions requiring tools for fiber tracking, tractography segmentation and estimation of intersubject correspondence. This paper proposes a novel, template matching approach to the problem. In the proposed method, a deformable fiber-bundle model is aligned directly with the subject tensor field, skipping the fiber tracking step. Furthermore, the use of a common template eliminates the need for tractography segmentation and defines intersubject shape correspondence. The method is validated using phantom DTI data and applications are presented, including automatic fiber-bundle reconstruction and tract-based morphometry.
journal_name
Neuroimagejournal_title
NeuroImageauthors
Eckstein I,Shattuck DW,Stein JL,McMahon KL,de Zubicaray G,Wright MJ,Thompson PM,Toga AWdoi
10.1016/j.neuroimage.2009.01.065subject
Has Abstractpub_date
2009-08-01 00:00:00pages
T82-9eissn
1053-8119issn
1095-9572pii
S1053-8119(09)00113-Xjournal_volume
47 Suppl 2pub_type
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