Abstract:
:Life requires monitoring and adjusting behavior in the face of conflicts. The conflict monitoring theory implicates the anterior cingulate cortex (ACC) in these processes; its ventral aspect (vACC) specializes in emotional conflict. To elucidate the underpinning neural mechanism, we recorded vACC extracellular activity from 12 patients with mood disorders or epilepsy who performed the face-emotional Stroop task. Behaviorally, both conflict detection and adaptation to conflict were evident. The firing rate of neurons in the vACC represented current conflict, i.e., current-congruency. The late onset of the effect is compatible with a role in monitoring. Additionally, early responses of some neurons represented the immediate history of conflicts, i.e., previous-trial-congruency. Finally, in some neurons the response to the current-trial was modulated by previous-trial-congruency, laying the ground for adjusting-to-conflicts. Our results uncover a single neuron level mechanism in the vACC that encodes and integrates past and present emotional conflicts, allowing humans to accommodate their responses accordingly.
journal_name
Neuroimagejournal_title
NeuroImageauthors
Shapira-Lichter I,Strauss I,Oren N,Gazit T,Sammartino F,Giacobbe P,Kennedy S,Hutchison WD,Fried I,Hendler T,Lozano AMdoi
10.1016/j.neuroimage.2018.03.028subject
Has Abstractpub_date
2018-07-15 00:00:00pages
45-55eissn
1053-8119issn
1095-9572pii
S1053-8119(18)30238-6journal_volume
175pub_type
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