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Event-related fMRI: characterizing differential responses.

Abstract：

:We present an approach to characterizing the differences among event-related hemodynamic responses in functional magnetic resonance imaging that are evoked by different sorts of stimuli. This approach is predicated on a linear convolution model and standard inferential statistics as employed by statistical parametric mapping. In particular we model evoked responses, and their differences, in terms of basis functions of the peri-stimulus time. This facilitates a characterization of the temporal response profiles that has a high effective temporal resolution relative to the repetition time. To demonstrate the technique we examined differential responses to visually presented words that had been seen prior to scanning or that were novel. The form of these differences involved both the magnitude and the latency of the response components. In this paper we focus on bilateral ventrolateral prefrontal responses that show deactivations for previously seen words and activations for novel words.

journal_name

Neuroimage

journal_title

NeuroImage

authors

Friston KJ,Fletcher P,Josephs O,Holmes A,Rugg MD,Turner R

doi

10.1006/nimg.1997.0306

subject

Has Abstract

pub_date

1998-01-01 00:00:00

pages

30-40

issue

1

eissn

1053-8119

issn

1095-9572

pii

S1053-8119(97)90306-2

journal_volume

7

pub_type

杂志文章

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