Structural brain variation and general intelligence.

Abstract:

:Total brain volume accounts for about 16% of the variance in general intelligence scores (IQ), but how volumes of specific regions-of-interest (ROIs) relate to IQ is not known. We used voxel-based morphometry (VBM) in two independent samples to identify substantial gray matter (GM) correlates of IQ. Based on statistical conjunction of both samples (N = 47; P < 0.05 corrected for multiple comparisons), more gray matter is associated with higher IQ in discrete Brodmann areas (BA) including frontal (BA 10, 46, 9), temporal (BA 21, 37, 22, 42), parietal (BA 43 and 3), and occipital (BA 19) lobes and near BA 39 for white matter (WM). These results underscore the distributed neural basis of intelligence and suggest a developmental course for volume--IQ relationships in adulthood.

journal_name

Neuroimage

journal_title

NeuroImage

authors

Haier RJ,Jung RE,Yeo RA,Head K,Alkire MT

doi

10.1016/j.neuroimage.2004.04.025

keywords:

subject

Has Abstract

pub_date

2004-09-01 00:00:00

pages

425-33

issue

1

eissn

1053-8119

issn

1095-9572

pii

S1053811904002332

journal_volume

23

pub_type

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