Abstract：
:The temporal characteristics of the BOLD response in sensorimotor and auditory cortices were measured in subjects performing finger tapping while listening to metronome pacing tones. A repeated trial paradigm was used with stimulus durations of 167 ms to 16 s and intertrial times of 30 s. Both cortical systems were found to be nonlinear in that the response to a long stimulus could not be predicted by convolving the 1-s response with a rectangular function. In the short-time regime, the amplitude of the response varied only slowly with stimulus duration. It was found that this character was predicted with a modification to Buxton's balloon model. Wiener deconvolution was used to deblur the response to concatenated short episodes of finger tapping at different temporal separations and at rates from 1 to 4 Hz. While the measured response curves were distorted by overlap between the individual episodes, the deconvolved response at each rate was found to agree well with separate scans at each of the individual rates. Thus, although the impulse response cannot predict the response to fully overlapping stimuli, linear deconvolution is effective when the stimuli are separated by at least 4 s. The deconvolution filter must be measured for each subject using a short-stimulus paradigm. It is concluded that deconvolution may be effective in diminishing the hemodynamically imposed temporal blurring and may have potential applications in quantitating responses in eventrelated fMRI.
journal_name
Neuroimagejournal_title
NeuroImageauthors
Glover GHdoi
10.1006/nimg.1998.0419keywords:
subject
Has Abstractpub_date
1999-04-01 00:00:00pages
416-29issue
4eissn
1053-8119issn
1095-9572pii
S1053811998904190journal_volume
9pub_type
临床试验,杂志文章相关文献
NEUROIMAGE文献大全abstract：:The "language-ready" brain theory suggests that the infant brain is pre-wired for language acquisition prior to language exposure. As a potential brain marker of such a language readiness, a leftward structural brain asymmetry was found in human infants for the Planum Temporale (PT), which overlaps with Wernicke's are...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2020.117575
更新日期：2020-12-04 00:00:00
abstract：:Functional MRI (fMRI) is an important tool for pre-surgical localization of eloquent cortex prior to resection of brain lesions. To increase the inherently low activation signal to noise ratio, fMRI pre-processing steps often include spatial smoothing. However, the effects of smoothing in the presence of brain lesions...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2006.06.051
更新日期：2006-11-01 00:00:00
abstract：:Many vertebrates communicate with ultrahigh frequency (UHF) vocalizations to limit auditory detection by predators. The mechanisms underlying the neural encoding of such UHF sounds may provide important insights for understanding neural processing of other complex sounds (e.g. human speeches). In the auditory system, ...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2015.04.007
更新日期：2015-07-01 00:00:00
abstract：:Using the intrinsic signal optical recording technique, we reconstructed the two-dimensional pattern of stimulus-evoked neuronal activities in the auditory cortex of anesthetized and paralyzed cats. The average magnitude of intrinsic signal in response to a pure tone stimulus increased steadily as the sound pressure l...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2004.08.021
更新日期：2004-12-01 00:00:00
abstract：:Whole brain extraction is an important pre-processing step in neuroimage analysis. Manual or semi-automated brain delineations are labour-intensive and thus not desirable in large studies, meaning that automated techniques are preferable. The accuracy and robustness of automated methods are crucial because human exper...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2010.12.067
更新日期：2011-04-01 00:00:00
abstract：:Myelin water imaging (MWI) promises to be invaluable in understanding neurological diseases like MS. However, a limitation of MWI is signal to noise ratio. Recently, a number of investigators have performed MWI at field strengths higher than 1.5 T. Our goal was to determine if myelin water imaging at increased SNR, ar...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2007.12.008
更新日期：2008-05-01 00:00:00
abstract：:Some eighty years after the discovery of the human electroencephalogram (EEG) and its dominant rhythm, alpha (~10Hz), the neurophysiological functions and behavioral correlates of alpha oscillations are still under debate. Similarly, the biological mechanisms contributing to the general factor of intelligence, or g, h...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2013.04.059
更新日期：2013-10-01 00:00:00
abstract：:Human communication and survival depend on effective social information processing. Abundant behavioral evidence has shown that humans efficiently judge preferences for other individuals, a critical task in social interaction, yet the neural mechanism of this basic social evaluation, remains less than clear. Using a s...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2010.02.044
更新日期：2010-06-01 00:00:00
abstract：:Temporal connectives (before/after) give us the freedom to describe a sequence of events in different orders. Studies have suggested that 'before-initiating' sentences, in which events are expressed in an order inconsistent with their actual order of occurrence, might need additional computation(s) during comprehensio...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2011.11.039
更新日期：2012-02-15 00:00:00
abstract：:Multi-echo fMRI, particularly the multi-echo independent component analysis (ME-ICA) algorithm, has previously proven useful for increasing the sensitivity and reducing false positives for functional MRI (fMRI) based resting state connectivity studies. Less is known about its efficacy for task-based fMRI, especially a...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2016.07.049
更新日期：2016-11-01 00:00:00
abstract：:This paper presents the conjecture that functional integration may be mediated by the mutual induction and maintenance of stereotyped spatiotemporal patterns of activity (i.e., transients) in different neuronal populations. In contradistinction to temporal and rate coding models of neuronal interactions, transient cod...
journal_title：NeuroImage
pub_type： 杂志文章,评审
doi：10.1006/nimg.1997.0260
更新日期：1997-04-01 00:00:00
abstract：:Large amounts of multimodal neuroimaging data are acquired every year worldwide. In order to extract high-dimensional information for computational neuroscience applications standardized data fusion and efficient reduction into integrative data structures are required. Such self-consistent multimodal data sets can be ...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2015.03.055
更新日期：2015-08-15 00:00:00
abstract：:Although East Asia harbors the largest number of aging adults in the world, there is currently little data clarifying the longitudinal brain-cognition relationships in this group. Here, we report structural MRI and neuropsychological findings from relatively healthy Chinese older adults of the Singapore-Longitudinal A...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2016.10.016
更新日期：2017-02-15 00:00:00
abstract：:The current paper focuses on a relatively new and promising area of the study of EEG transformations during brain information processing based on the reduction of the signal to the discrete quasi-stationary segment sequences which may reflect individual brain microstates or discrete operations. In this framework, the ...
journal_title：NeuroImage
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/j.neuroimage.2004.03.013
更新日期：2004-07-01 00:00:00
abstract：:Noise usually affects the reliability of quantitative analysis in diffusion-weighted (DW) magnetic resonance imaging (MRI), especially at high b-values and/or high spatial resolution. Higher-order singular value decomposition (HOSVD) has recently emerged as a simple, effective, and adaptive transform to exploit sparse...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2017.04.017
更新日期：2017-08-01 00:00:00
abstract：:The degree of interhemispheric synchrony in the neonatal EEG assessment refers to the co-occurrence of activity bouts during quiet sleep or burst suppression, and it has been widely considered as a key component in assessing background activity. However, no objective measures have been published for measuring it, and ...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2012.12.017
更新日期：2013-04-01 00:00:00
abstract：:Understanding the neurocognitive basis of risk-taking behavior is an important issue, especially in economic decision-making. Classical behavioral studies have shown that risk-attitude changes across different contexts, but little is so far known about the brain correlates of processing of outcomes across such context...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2009.08.068
更新日期：2010-01-15 00:00:00
abstract：:The extent to which visual word perception engages speech codes (i.e., phonological recoding) remains a crucial question in understanding mechanisms of reading. In this study, we used functional magnetic resonance imaging techniques combined with behavioral response measures to examine neural responses to focused vers...
journal_title：NeuroImage
pub_type： 临床试验,杂志文章
doi：
更新日期：2002-10-01 00:00:00
abstract：:Electrophysiological and neuroimaging evidence suggest the existence of common mechanisms for monitoring erroneous events, independent of the source of errors. Previous works have described modulations of theta activity in the medial frontal cortex elicited by either self-generated errors or erroneous feedback. In tur...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2015.07.012
更新日期：2015-10-15 00:00:00
abstract：:Development of working memory (WM) aptitude parallels structural changes in the frontal-parietal association cortices important for performance within this cognitive domain. The cerebellum has been proposed to function in support of the postulated phonological loop component of verbal WM, and along with frontal and pa...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2008.05.057
更新日期：2008-10-01 00:00:00
abstract：:The recording of electrophysiological data during BOLD fMRI is highly challenging but provides the opportunity to develop a more thorough account of brain function than either modality alone. To develop new techniques in this area has often required the study of pathological electrophysiological measures because such ...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2006.04.183
更新日期：2006-08-15 00:00:00
abstract：:Diseases involving the medial temporal lobes (MTL) such as Alzheimer's disease and mesial temporal sclerosis pose an ongoing diagnostic challenge because of the difficulty in identifying conclusive imaging features, particularly in pre-clinical states. Abnormal neuronal connectivity may be present in the circuitry of ...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2012.05.065
更新日期：2012-09-01 00:00:00
abstract：:Cognitive control processes refer to the ability to flexibly adapt one's thoughts and actions in the pursuit of an internal goal. Task preparation is a central aspect of cognitive control and has generally been studied using explicitly cued task-switching paradigms. Over the last decade, numerous fMRI studies have ide...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2013.03.057
更新日期：2013-08-15 00:00:00
abstract：:Many cognitive theories of semantic organization stem from reports of patients with selective, category-specific deficits for particular classes of objects (e.g., fruit). The anatomical assumptions underlying the competing claims can be evaluated with functional neuroimaging but the findings to date have been inconsis...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1006/nimg.2001.1002
更新日期：2002-03-01 00:00:00
abstract：:Neuropathological events featuring early stages of Alzheimer's disease (AD) appear in the entorhinal cortex (EC), subiculum (SB) and cornu ammonis 1 (CA1) of hippocampus, which may account for associative memory deficits in non-demented people with mild cognitive impairment (MCI). To test this hypothesis in vivo, we i...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2011.05.047
更新日期：2011-08-15 00:00:00
abstract：:Our visual system readily groups dynamic fragmented input into global objects. How the brain represents global object perception remains however unclear. To address this question, we recorded brain responses using functional magnetic resonance imaging whilst observers viewed a dynamic bistable stimulus that could eith...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2020.116926
更新日期：2020-10-15 00:00:00
abstract：:Model-based analysis methods for fMRI data assume a priori knowledge of the time course of the hemodynamic response (HR) in reaction to experimental stimuli or events. This knowledge is incorporated into the hemodynamic response function (HRF), which is a common model of the HR. Although it is already known that the H...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2006.06.003
更新日期：2006-09-01 00:00:00
abstract：:We present a new framework for prior-constrained sparse decomposition of matrices derived from the neuroimaging data and apply this method to functional network analysis of a clinically relevant population. Matrix decomposition methods are powerful dimensionality reduction tools that have found widespread use in neuro...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2014.05.026
更新日期：2014-10-01 00:00:00
abstract：:Modern neuroimaging technologies afford a non-invasive view into the functions of the human brain with great spatial (fMRI) and temporal resolution (EEG). However, common signal analytic methods require averaging over many trials, which limits the potential for practical application of these technologies. In this pape...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2008.03.031
更新日期：2008-08-15 00:00:00
abstract：:Magnetic susceptibility based (T(2)* weighted) contrast in MRI at high magnetic field strength is of great value in research on brain structure and cortical architecture, but its use is hampered by the low signal-to-noise ratio (SNR) efficiency of the conventional spoiled gradient echo sequence (GRE) leading to long s...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2011.03.046
更新日期：2011-06-15 00:00:00
